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실무자 인터뷰를 통한 청주시 아동 그룹홈의 주거 개선 요구 조사
이상우,이민서,우자강,이현정,Lee, Sang Woo,Yi, Minseo,You, Zikang,Lee, Hyun-Jeong 인천대학교 도시과학연구원 2020 도시과학 Vol.9 No.2
The purpose of this study was to assess needs for housing improvement of children group homes in Cheongju-si through interviews with the group home directors and staffs. From April 6, 2018, to April 25, 2018, a series of face-to-face interviews with four directors and three staffs working in four children group homes was conducted. The results were analyzed using thematic analysis technique. Highlights of major findings and implications were as follow: (1) Bedroom: Needs for independent bedrooms and desks for each child were dominant. (2) Common activity space: Interviewees showed somewhat different opinions on common activity spaces according to group home types and/or between directors and staffs. (3) Between "a big and good-quality house" and "a house in good location", interviewees were found to prefer "a big and good-quality house" in order for children to have enough space to run and play. (4) Interviewees insisted that to provide proper group home services and protection similar to a real family, current policy to accommodate up to eight children in one group home should be improved.
Crystal Structures of the Two Isomorphous A-DNA Decamers d(GTACGCGTAC) and d(GGCCGCGGCC)
김태균,권택훈,정혜선,구자강,Muttaiya Sundaralingam,반창일 대한화학회 2006 Bulletin of the Korean Chemical Society Vol.27 No.4
To study the effect of sequence on DNA structure, the two decamer crystal structures one alternating, d(GTACGCGTAC), and the other non-alternating, d(GGCCGCGGCC), were solved. Crystals of both decamers belong to the hexagonal space group P6122, with one strand in the asymmetric unit. The unit cell constants of the alternating decamer are a = b = 39.26 Å, c = 77.70 Å. The structure was refined with 1,828 reflections from 8.0 to 2.0 Å resolution to an R value of 21.3% with all DNA atoms and 63 water molecules. The isomorphous non-alternating decamer had unit cell dimensions of a = b = 39.05 Å, c = 82.15 Å. The structure was refined with 2,423 reflections from 8.0 to 2.0 Å resolution to a final R value of 22.2% for all DNA atoms and 65 water molecules. Although the average helical parameters of the decamers are typical of A-DNAs, there are some minor differences between them. The helical twist, rise, x-displacement, inclination and roll alternate in the alternating decamer, but do not in the non-alternating decamer. The backbone conformations in both structures show some differences; the residue G(7) of the alternating decamer is trans for a and g while the trans conformations are observed at the residue G(8) of the non-alternating decamer.
H.S.Son,구자강 대한화학회 2002 Bulletin of the Korean Chemical Society Vol.23 No.2
Unsaturated Cr(CO) x (1 ? x ? 5) molecules were generated in the gas phase from photolysis of Cr(CO) 6 vapor in He using an unfocussed weak UV laser pulse and their reactions with O 2 and N 2 O have been studied. The formation and disappearance of the ground state CrO molecules were identified by monitoring laser-induced fluorescence(LIF) intensities vs delay time between the photolysis and probe pulses. The photolysis laser power dependence as well as the delay time dependence of LIF intensities from the CrO orange system showed different behavior as those from ground state Cr atoms, suggesting that the ground state CrO molecules were generated from the reaction between O 2 /N 2 O and photo- fragments of Cr(CO) 6 by one photon absorption. The depletion rate constants for the ground state CrO by O 2 and N 2 O are 5.4 ± 0.2 × 10 −11 and 6.5 ± 0.4 × 10 −12 cm 3 molecule −1 s −1 , respectively.
An Eurpium(III) Hydrolytic Catalyst Favoring Anionic Phosphate Esters over Phosphate Triester'
윤창원,오순진,전영진,최영서,손윤경,황보석,구자강,박준원,Yun, Chang Won,O, Sun Jin,Jeon, Yeong Jin,Choe, Yeong Seo,Son, Yun Gyeong,HwangBo, Seok,Gu, Ja Gang,Park, Jun Won Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.2
A Cryptate (221) having a short alcohol pendant (2) was metallated with europium(Ⅲ) in anhydrous condition, and its hydrolytic activity for phosphate esters at neutral pH was examined. While the activity for the phosphate diester and monoester is comparable to that of the parent metal complex [1Eu]3+, its hydrolytic activity towards a phosphate triester is significantly suppressed. Potentiometric titration and luminescence spectroscopic studies for the equilibrium behavior of the complex in solution suggest that a dimer formation through the metal hydroxides as well as the pendant alcohol is likely to happen. The low hydrolytic activity for the triester seems to be associated with the dimer formation.
Simple Screening Method for Double-strand DNA Binders Using Hairpin DNA-modified Magnetic Beads
Hunho Jo,Kyoungin Min,Kyung-mi Song,구자강,한민수,반창일 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.1
We designed an effective screening method for double strand DNA (dsDNA) binders using DNA-modified magnetic particles. Hairpin DNA was immobilized on the surface of magnetic particle for a simple screening of dsDNA binding materials in a solution containing various compounds. Through several magnetic separation and incubation processes,four DNA-binding materials, DAPI, 9AA, AQ2A, and DNR, were successfully screened from among five candidates. Efficiency of screening was demonstrated by HPLC analysis using a C2/18 reverse-phase column. In addition, their relative binding strengths were verified by measuring the melting temperature (T_m). If hairpin DNA sequence is modified for other uses, this magnetic bead-based approach can be applied as a high-throughput screening method for various functional materials such as anti-cancer drugs.