잠재프로파일분석을 활용한 세대집단별 가족가치관 유형화 연구

김유나,박애리 한국거버넌스학회 2022 한국거버넌스학회보 Vol.29 No.2

우리 사회는 오랜 시간에 걸쳐 전통적 가족에 대한 가치 변화가 일어나고 있는 현상을 인식하고 있고, 이러한 현상이 우리 사회에 미치는 영향에 대한 논의를 활발하게 이어가고 있다. 그러나 이러한 현상이 세대집단별로 어떠한 양상으로 일어나고 있는지 실증적으로 규명한 연구는 매우 부족한 상황이다. 이에 본 연구는 여성가족부의 「2020년 가족실태조사」 데이터를 활용하여 결혼관, 가족의례 및 문화, 성역할 인식 및 부모 부양과 자녀양육에 대한 인식을 중심으로 20대부터 70대 이상까지 세대별 가족가치가 유형화 되는지살펴보았다. Mplus를 이용하여 잠재프로파일분석(Latent Profile Analysis, LPA)을 실시한 결과, 20대와 30대가 다른 세대에 비해 비전통적인 성향이 강한 유형화를 보였다. 결혼관과 가족의례 및 문화에 있어개방적이고 자유로우며, 성평등적이고, 부모부양과 자녀관에 있어 의무와 당위성이 약화된 개인주의적 성향으로 나타났다. 다만, 성평등에 있어서는 20대가 30대보다 좀 더 강한 성평등적 속성을 보였다. 40대와50대에서는 가족가치관에 있어 전통적인 성향과 비전통적인 성향이 동시에 나타났으며, 50대가 전통적인성향이 좀 더 강했다. 결혼관과 가족의례 및 문화에 있어 40대 대다수는 자유주의적 성향으로 나타난 반면, 50대는 대다수가 전통적인 성향으로 나타났다. 부양관과 자녀관에 있어서도 비슷한 패턴을 보였다. 다만, 성역할에 있어서는 40대와 50대 모두에서 성평등적인 유형화가 우세하게 나타났다. 마지막으로, 60대와70대에서는 전반적으로 전통적인 유형화가 우세하게 나타났다. 특히, 결혼관과 가족의례 및 문화에서 전통적인 가치를 강하게 유지하는 것을 알 수 있었다. 부양관과 자녀관에 있어서는 여전히 대다수가 전통적인성향으로 유형화 되었지만, 소수가 개인주의적 성향으로 유형화 되었다. 그러나, 성역할에 있어서는 60대의 상당수가 성평등한 유형화에 속했고, 70대에서도 성평등한 유형화가 나타났다. 이와 같은 연구 결과를토대로 세대별 가족에 대한 가치관을 반영한 가족정책 개발에 관한 정책적 함의를 논하였다.

Hydrophobic Coated ACF with High Surface Area for EnhancedWarfare Agents Protection Efficiency

김유나,홍진기 한국고분자학회 2023 한국고분자학회 학술대회 연구논문 초록집 Vol.48 No.1

The Effect of Non-Payment, Optional Treatment, and Hospitalization Decision on the Payment of Medical Expenses

김유나,이현지,김재현 융합연구학회 2022 융합연구학회지 Vol.6 No.3

The purpose of this study is to provide the basic data for related policies by analyzing the relationship between the non-payment, optional treatment, hospitalization decision, and the payment of medical expenses. A total of 7,317 inpatients were selected as the final subjects using the 2011-2015 data of the Korea Medical Panel. It was analyzed using the chi-square test and the generalized estimating equation (GEE), and the demographic variables affecting payment of medical expenses and use of medical treatment variables were included as the correction variables. As a result of the analysis performed, compared to the inpatients with non-payment expenditures less than 250,000 won, 250,000 won to 500,000 won (OR: 1.19 95% CI: 1.01-1.39, P-value: 0.0319), 500,000 won to less than 1 million won (OR: 1.75 95% CI: 1.46-2.09, P-value: <.0001), over 1 million won (OR: 1.58 95% CI: 1.27-1.96, P-value: <.0001), there was a burden on the expenditure of medical expenses. Furthermore, while there was no recommendation for optional treatment, the inpatients who received optional treatment had a higher payment of medical expenses compared to the inpatients who did not (OR: 1.20 95% CI: 1.00-1.45, P-value: 0.0490). The patients who decided to be hospitalized had a higher payment of medical expenses than those who decided to be hospitalized by themselves (OR: 1.14 95% CI: 1.03-1.27, P-value: 0.0149). As a result of this study, the non-payment, optional treatment, and the hospitalization decision had an effect on the payment of medical expenses. Optional treatment was closed after 2018, but the payment of medical expenses due to the non-payment and the hospitalization decisions still exists, and hence, there is a need for the policy improvement to reduce them.

Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis

김유나,최소라,조경화,조도연,강재구,박창교,이회영 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Hippo/YAP signaling is implicated in tumorigenesis and progression of various cancers. By inhibiting a plethora signaling cascades, resveratrol has strong anti-tumorigenic and anti-metastatic activity. In the present study, we demonstrate that resveratrol decreases the expression of YAP target genes. In addition, our data showed that resveratrol attenuates breast cancer cell invasion through the activation of Lats1 and consequent inactivation of YAP. Strikingly, we also demonstrate that resveratrol inactivates RhoA, leading to the activation of Lats1 and induction of YAP phosphorylation. Further, resveratrol in combination with other agents that inactivate RhoA or YAP showed more marked suppression of breast cancer cell invasion compared with single treatment. Collectively, these findings indicate the beneficial effects of resveratrol on breast cancer patients by suppressing the RhoA/Lats1/YAP signaling axis and subsequently inhibiting breast cancer cell invasion.

Comparison between weekly versus 3-weekly paclitaxel in combination with carboplatin as neoadjuvant chemotherapy in advanced ovarian cancer

김유나,이용재,이정윤,남은지,김상운,김성훈,김영태 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.2

Objective: To compare the efficacy and toxicity of dose-dense weekly paclitaxel and 3-weekly carboplatin (ddPC) as neoadjuvant chemotherapy (NAC) with the standard 3-weekly regimen. Methods: A retrospective study of patients diagnosed with stage IIIc and IV ovarian cancer who received at least one cycle of NAC followed by interval debulking surgery between August 2015 and January 2018 was conducted. Patient characteristics, clinical and pathological response to NAC, surgical and survival outcome, and adverse event were compared. Results: A total of 23 patients in the ddPC group and 50 patients in the standard group received a median of 3 cycles of NAC. Rate of grade ≥3 neutropenia was significantly higher in the ddPC group than the standard (82.6% vs. 22.0%, p<0.001). Patients in the ddPC group underwent dose-reduction more frequently (34.8% vs. 4.00%, p=0.001). Normalization of cancer antigen-125 post-NAC occurred more frequently in the ddPC group (73.9% vs. 46.0%, p=0.030). No residual disease rate (43.5% vs. 60.0%, p=0.188) and chemotherapy response score of 3 (34.8% vs. 26.0%, p=0.441) were not statistically different between two groups. There was no statistical difference in progression free survival (PFS) at 2 years (36.3% vs. 28.4%, p=0.454). Cox proportional hazard model showed that ddPC was not a significant determinant of PFS (p=0.816). Conclusion: There was no difference between both regimens in terms of NAC response and survival outcomes. However, ddPC group showed higher hematologic toxicity requiring dose reduction.

Microstructural Modification of NiAl Layered Double Hydroxide Electrodes by Adding Graphene Nanosheets and Their Capacitative Property

김유나,김석 대한화학회 2015 Bulletin of the Korean Chemical Society Vol.36 No.2

NiAl layered double hydroxide (LDH) composite electrodes containing various contents of graphene nanosheets (GNS) were prepared by a hydrothermal method. The micro-structure and morphological properties were examined by FE-SEM, FE-TEM, XRD, and FTIR. Electrochemical analysis was also carried out by cyclic voltammetry, impedance, and cycle life measurement. The as-prepared composite that contained 500 mg of graphene (denoted as NiAl/G-50) achieved the highest specific capacitance of 1147 F/g among the various NiAl LDH/GNS composites. Besides, the NiAl LDH/GNS composite exhibited the lower diffusion resistance, improved rate capability, and good cyclic stability (83% of initial capacitance after 2000 cycles). Considering the morphological data and the improved capacitative properties together, we concluded the synthesized NiAl LDH/GNS composites would be a promising electrode material for supercapacitors.

고령층 디지털 정보 역량과 디지털 정보 활용 영향요인에 관한 연구

김유나,변은지 한국디지털정책학회 2021 디지털융복합연구 Vol.19 No.3

헬스헬퍼

김유나,오미화,김치수 한국정보기술학회 2018 Proceedings of KIIT Conference Vol.2018 No.11

Factors Associated with Cheyne-Stokes Respiration in Acute Ischemic Stroke

김유나,김성헌,류동열,이서영,임경빈 대한신경과학회 2018 Journal of Clinical Neurology Vol.14 No.4

Background and Purpose Cheyne-Stokes respiration (CSR) is frequently observed in patients with acute stroke. There have been conflicting opinions about the associations of CSR with the location and size of the lesion. We aimed to better define the clinical relevance and pathogenesis of CSR in acute stroke. Methods We investigated patients who had been admitted with acute ischemic stroke and received an overnight sleep apnea test. We collected data on demographics, risk factors, etiologic subtypes, initial vital signs, clinical course of the stroke, and parameters associated with respiratory events during the sleep apnea test. We performed a multivariate logistic regression analysis to determine the factors associated with CSR. Results Among 182 patients, 35 patients showed CSR in sleep apnea testing. Large-artery atherosclerosis or cardioembolism, bilateral hemispheric involvement, atrial fibrillation, low left-ventricle ejection fraction (LVEF), and left atrium (LA) enlargement were all associated with the presence of CSR. Multivariate analysis revealed that the previous modified Rankin Scale (mRS) score, bilateral hemispheric involvement, low LVEF, and LA enlargement were significantly associated with CSR. Subgroup analysis with large-artery atherosclerosis without cardiac disease revealed that the previous mRS score is the only independent factor associated with CSR. Conclusions CSR frequently occurs in strokes involving large arteries or due to cardioembolism, regardless of the location and severity of the stroke. Predisposing conditions such as preexisting neurologic disability, low LVEF, and LA enlargement are associated with CSR in acute stroke.

잠재프로파일분석을 활용한 Z세대 10대 청소년 가족가치관 유형분석 및 영향요인 탐색

김유나,이민영 한국가족학회 2023 가족과 문화 Vol.35 No.4

The study focused on understanding the changing family values among Generation Z teenagers and aimed to predict future changes in social families by analyzing these values. To this end, the family values of teenagers in Generation Z were categorized, focusing on perspective of marriage, child, and family support, and family rituals, various family acceptance and the characteristics of each family value type were analyzed. The study used data from 5,734 middle and high school students in South Korea and employed Latent Profile Analysis (LPA) and logistic regression analysis as its analytical methods. The key findings were that the family values of Generation Z teenagers were categorized into two groups: “family-centered group” and “individualistic group.” The family-centered group comprised 39.2% of the participants, while the individualistic group made up 60.8%. Several factors including gender, the importance of family, social fairness, and social gender equality predicted the type of family values in Generation Z. These findings informed family policies to adapt them to the evolving needs and preferences of younger generations, and contributed to a deeper understanding of the changing dynamics of family and society. 본 연구는 우리 사회 가족의 변화와 함께 가족가치관이 변화하고 있는 현상에 주목하고, 기성세대와 구별되는 Z세대 10대 청소년의 가족가치관을 이해함으로써 미래 사회 가족의 변화 양상을 예측하는 하는데 목적이 있다. 이를 위해 가족가치관을 구성하는 결혼관, 자녀관, 부양관, 가족의례, 다양한 가족 수용성을 중심으로 Z세대 10대 청소년들의 가족가치관을 유형화하고, 각 유형별 특성을 분석하였다. 또한 이 같은 유형을 구분짓는 영향요인들을 탐색해봄으로써 가족가치관의 변화 양상에 대한 이해의 폭을 넓히고자 하였다. 실증적 분석을 위해한국청소년정책연구원의 「Z세대 10대 청소년의 가치관 변화 연구」에서 전국 중고등학생을대상으로 층화다단계집락표집을 통해 구축한 5,734명의 데이터를 활용하였다. 분석방법으로는 잠재프로파일분석(Latent Profile Analysis, LPA)과 로지스틱회귀분석을 실시하였다. 분석결과 Z세대 10대 청소년의 가족가치관은 ‘가족중심주의 집단’과 ‘개인주의 집단’ 2개 집단으로 유형화 되었고, 가족중심주의 집단은 39.2%, 개인주의 집단은 60.8%로 개인주의 집단이더 많은 것으로 나타났다. 가족가치관 유형을 예측하는 요인으로는 성별, 가족중요도 인식, 사회 공정성에 대한 인식, 사회 성평등성에 대한 인식이 통계적으로 유의한 수준에서 영향을미치는 것으로 확인되었다. 본 연구는 Z세대 10대 청소년의 가족가치관 유형과 특성 이해에기반하여 미래 사회 가족의 변화를 예측함과 동시에 가족정책 방향의 시사점을 제시했다는점에서 의미가 있다.