고려인삼이 흰쥐의 악하선 조직 핵산 함유량에 미치는 영향

김승훈 최신의학사 1971 最新醫學 Vol.14 No.5

A study was planned to see if administration of ginseng extract has any influence upon the nucleic acid content of the mandibular gland of rats, and to estimate the effect of ACTH administration upon the nucleic acid content of rats previously primed with ginseng. Ninety male rats (body weight: 150-200 gm) were divided into the ginseng, the saline, and the normal groups, which received for 5 days 0.5 ml /100 gm body weight of ginseng extract solution (4 mg of ginseng alcohol extract in 1 ml of saline), same amount of saline, or no medication, respectively. On the 5th experimental day, each of the 3 groups was further divided into 2 subgroups yielding the ginseng, the ginseng-ACTH, the saline, the saline?ACTH, the normal, and the normal-ACTH subgroups. The ginseng, the saline, and the normal subgroups were sacrificed 2 hours after the last medication, while the ginseng-ACTH, the saline-ACTH, and the normal-ACTH subgroups received ACTH (0.1 unit/subject) 1 hour after the last medication and were sacrificed after 1 more hour. The mandibular gland was measured for RNA and DNA contents using the chemical method of Schmidt-Thanhauser-Schneider. Following results were obtained 1. RNA content of the mandibular gland and RNA/DNA ratio were significantly higher in the ginseng group than they were in the normal and the saline groups. The DNA content was significantly reduced in the ginseng group. 2. Administration of ACTH reduced nucleic acid contents of the mandibular gland. In the ginseng group the rate of decrease ((value of ginseng-ACTH subgroup-value of ginseng subgroup) X 100/value of ginseng subgroup) in RNA and RNA/DNA ratio were more conspicuous than they were in the normal and the saline groups. The rate of decrease in DNA after ACI'II was less conspicuous in the ginseng group. Thus under the influence of ginseng the mandibular glandular RNA content and RNA/DNA ratio increased significantly and DNA content decreased conspicuously while under additional influence of ACTH the rate of decrease was conspicuous in RNA content and RNA/DNA ratio but it was less so in DNA content.

보로노이 다이어그램을 이용한 지문정합 알고리즘

김승훈,최태영 대한전자공학회 2004 電子工學會論文誌-SP (Signal processing) Vol.41 No.6

This paper proposes a matching algorithm using Voronoi diagram for rotation and translation invariant fingerprint identification. The proposed algorithm extracts geometrical structures that are derived from Voronoi diagram of a fingerprint image. Then two features, distances and angles are extracted from the geometrical structures and saved as indexing form for fingerprint matching. This matching algerian has a lower error rate than indexing based methods of old times. 본 논문에서는 검출된 특징점에 대해 보로노이 다이어그램을 사용하여 이동과 회전에 불변인 정합 알고리즘을 제안한다. 보로노이 다이어그램에 의해서 검출되는 각각의 특징점과 그에 인접한 특징점들 사이의 거리와 각도를 데이터베이스에 저장하고 인증을 요청한 지문의 정보를 같은 방법으로 변환 후 데이터베이스 내의 정보들과의 비교를 통해서 결과를 출력한다. 이는 기존의 인덱싱 기반 알고리즘에 비해 더욱 정확한 알고리즘이다.

검인정 교과서 김사 체제의 문제와 발전 방향

김승훈 中央大學校 韓國敎育問題硏究所 2002 韓國敎育問題硏究所論文集 Vol.- No.17

류마티스 관절염 환자에서 Conserved T 세포 수용체의 CDR3 motif를 표현하는 제2형 콜라겐 특이 T세포주의 형성과 유지

김승훈,조미라,윤지희,박성환,조철수,황수연,김호연,Kim, Seung-Hoon,Cho, Mi-La,Youn, Jeehee,Park, Sung-Hwan,Hwang, Sue-Yun,Cho, Chul-Soo,Kim, Ho-Youn 대한면역학회 2001 Immune Network Vol.1 No.1

Background: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). Methods: We generated CII-specific T-cell lines of 8 RA patients by prolonged in vitro culture with bovine CII (bCII) and the immunogenic peptide (256-270) of human CII. The proliferation response towards CII stimulation was measured from the uptake of 3H-thymidine. Changes in the secretion of Th 1 and Th2 cytokines in the culture supernatent were measured by ELISA. The TCR clonotypes of these T-cells were examined by RT-PCR/SSCP analyses of all 22 $V_{\beta}$ chains. Results: T-cells from patients' tissue exhibited strong proliferation index upon CII stimulation, which was maintained up to 6 months in the culture. The secretion of INF-$\gamma$from these T-cells increased along with the duration of culture time, while the amount of IL-4 production did not show significant changes. The SSCP band patterns of patients' T-cells appear as discrete bands unlike the smeary streak produced from normal samples. Some SSCP bands, each representing selected expansion of a TCR containing certain subtype of $V_{\beta}$ peptides, appeared to be identical in more than one patients. Among these, the expansion of SSCP band representing the $V_{\beta}$ 14 CDR3 region persisted after switching the antigen to the immunogenic human peptide (256-270). Conclusion: CII-reactive T-cells expressing distinct CDR3 motifs are selectively expanded in the peripheral blood and synovial fluid of RA patients, and their persistent proliferation upon CII stimulation, as well as the production Th 1-type cytokines, may play pivotal roles in RA pathogenesis.

영남대학교 의과대학 부속병원 외래환자에 대한 약물처방 동향의 분석

이광윤,김원준,김승훈 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1

대구 및 그 인접지역의 질병 발생 경향을 추정하고, 영남대학교 의과대학 부속병원의 약제수급 계획을 위한 참고자료를 얻기 위하여 1985년 3월부터 동년 8월까지 당 병원 외래에 내원한 환자들을 위하여 내려진 약물 처방을 전산 집계하여 다음과 같은 결과를 얻었다. 가장 빈번히 처방된 약물로 부터 100종의 약물을 처방빈도 순으로 나열하였던 바, diazepam, aluminum compound, acetaminophen, isoniazid,metoclopramide,?????????, carboxymethylcystien, ephedrine, codeine, caroverine(이하 생략) 등의 순으로 나타났으며, 이와 같이 선정된 100종의 약물을 임상용도별로 분류하여 총 처방회수 521,855회에 대한 백분율을 조사한 결과는 다음과 같다. 중추신경계약물(20.57%)이 가장 많았고, 다음은 위장관 및 평활근에 작용하는 약물(18.64%), 호흡기계약물(16.11%), 항균제(15.12%), 심혈관계약물(5.64%)의 순으로 많았으며, 그 다음은 소염제(4.33%), 단독비타민제(3.76%), 호르몬 및 항호르몬제(3.29%), 감기치료제(3.12%), 이뇨제(2.81%), 간기능이상치료제(2.02%), 자율신경계약물(1.89%), 항히스타민제(1.02%) 및 소독약(0.74%) 등의 순으로 나타났다. This report offers descriptive data about the drugs utilized in out patient department (OPD) of Yeungnam University Hospital (YUH) in the period of march to august in 1985. The data in this report were produced by the computerized totalization of the number of mentions of individual drugs included in the prescriptions. The 100 drug entries that were most frequently recorded are listed in rank order. The listing is arbiturarily restricted to the drugs that were prescribed as single preparations, the drugs of basis of compound preparations and the drugs of adjuvent or corrective of compound preparations that have significant therapeutic effects-either by generic names. And in addition, the listing also involves the compound preparations used in relatively large frequency, and the individual components of which have the unique pharmacologial actions each other by proprietary names. And all routes of administrations were allowed. The 10 drugs most frequently named are diazepam, aluminum compounds, acetaminophen, isoniazid, metoclopramide, ?????????, carboxymethylcystein, ephedrine, codeine and caroverine in order. The 521, 855 drug mentions listed as above are described by the chief therapeutic usage that each is intended to apply generally. The drugs which account the largest proportion of total mentions were those acting on the central nervous system(20.57%), including tranquillizers and sedative hypnotics(11.71%), analgesic antipyretics(5.55%), antidepressants(2.15%) etc. Gastrointestinal drugs and smooth muscle preparations(18.64%) included antacids and anti-ulcerdrugs(9.24%), antiemetics(3.57%), spasmolytics(3.14%) and others. Respiratory drugs (16.11%) included expectorants and cough preparation(10.99%) and bronchodilators(5.12%).Cardiovascular drugs (5.64%) included cardiac drugs and coronary vasodilator(4.12%) and antihypertensives and vasodilators(1.06%). And anti-inflammatory drugs(4.33%), vitamins of single preparations (3.76%), hormones and their antagonists(3.29%), common cold preparations(3.12%), diuretics(2.81%), drugs supporting liver function(2.02%), drugs affecting autonomic nervous system(1.89%) including anti-glaucomas, atropine and cerebral vasodilators, antihistamine drugs(1.02%) and disinfectants(0.74%) were following in order. The data in this report were compared to those reported by H. Koch, et al. in United States(US), 1981 as "Drugs Most Frequently Used in Office Practice: National Ambulatory Medical Case Survey, 1981." Cardiovascular drugs prescribed in YUH were much less in proportion than in US(10.56),but gastrointestinal drugs accounted the larger proportion than in US(3.72%). Expectorants and cough preparations in YUH also accounted the larger proportion than in US(2.74%). In conclusion, in the period of march to august, 1985, OPD of YUH prescribed the CNS drugs including diazepam most frequently, and gastrointestinal, repiratory and chemotherapeutic drugs in next orders. It is supposed that the eating habits of Koreans and a unique atmospheric condition in Taegu as a basin were some important factors that affected the proportions of drugs acting on gastrointestinal and repiratory tracts.

철근의 수직 비접촉 겹침에 대한 이음 성능

김승훈,문정호,이리형,이호진,하상수 대한건축학회 2006 大韓建築學會論文集 : 構造系 Vol.22 No.9

Recently, new moment-resisting precast concrete beam-column joint was proposed for moderate seismic regions. It has the connection reinforcing bars, penetrated the joint and lap-spliced with the bottom bars of precast U-beam. In this study, to evaluate the performance for noncontact lapped splice, experimental and analytical works were conducted. Major variables for tests and FEM analysis were the length of lap(0.8lb, 1.0lb, 1.2lb, 14lb) and the diameter of connection reinforcing bars(D19, D22, D25). Results of experimental and analytical works show that the these variables has much influence on strength and ductility, and deformation of lapped joint. Particularly, the size of splice bars had an effect on the splice performance of the vertical noncontact lapped bars.

지하구조물에 사용되는 합성 중공 슬래브의 휨 성능에 관한 실험적 연구

김승훈,강원석,김혜민,이리형 한밭대학교 2006 한밭대학교 논문집 Vol.23 No.-

Recently, many engineers have used Hollow Core Slab(HCS) system on buildings. However, they couldn't apply this system to underground level, because the axial force effect hasn't yet been clearly investigated. This paper presents the test results for structrual behaviors of composite HCS under axial and bending force. Variables are the thickness of topping concrete and the magnitude of axial forces. The topping thicknesses are 70mm and 100mm. The axial forces are OkN, 911.4kN, 1313.2kN. Test results showed that composite HCS had more strength capacity as the axial forces increase, and that HCS system could be applied to the underground structures with attention to the joint crack of cast-in-place concrete and HCS.

보로노이 다이어그램을 이용한 지문정합 알고리즘

김승훈,최태영 대한전자공학회 2004 電子工學會論文誌-SP (Signal processing) Vol.41 No.06

This paper proposes a matching algorithm using Voronoi diagram for rotation and translation invariant fingerprint identification. The proposed algorithm extracts geometrical structures that are derived from Voronoi diagram of a fingerprint image. Then two features, distances and angles are extracted from the geometrical structures and saved as indexing form for fingerprint matching. This matching algorithm has a lower error rate than indexing based methods of old times.

무상보육은 '복지 포퓰지즘' ?

김승훈 한국노동조합총연맹 2012 월간 한국노총 Vol.486 No.-

학생 죽음 앞에서도 경쟁 강조하는 한국사회의 자화상, KAIST

김승훈 한국노동조합총연맹 2011 월간 한국노총 Vol.471 No.-