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      • KCI등재

        뇌성마비 아동의 한의치료 양상 분석

        정현우,윤영주,허영진 대한한의학회 2019 대한한의학회지 Vol.40 No.1

        with cerebral palsy (CP) according to the disease characteristics. Methods: In a prospective observational multicenter study for children with CP, we analyzed 78 baseline questionnaires of children having experience of KM treatments such as acupuncture and Korean herbal medicine and 43 follow-up data of children who have received KM during the one observation year. Results: Of all the 182 participants, 38 children were currently getting KM treatment and 40 children have discontinued KM treatment. Children with non-spastic CP and more health problems tended to use KM. The most frequent reason for quitting acupuncture therapy was ‘suffering of children’ and the highest reason of stopping herbal medicine was ‘rejection of children’. Among the 133 participants finished one year follow-up, 43 children have received at least one KM treatment. The average number of acupuncture therapy was twice a week and the average monthly cost of acupuncture therapy and herbal medicine were 65,922 won and 476,003 won, respectively. Children under 32 month old have received significantly more acupuncture and children with non-spastic CP have taken significantly more herbal medicine. Conclusions: Further study will be required to confirm the effectiveness of KM and increase the utilization of KM among the children with CP. More efforts should be made to increase the convenience of acupuncture therapy and herbal medicine and to expand the insurance coverage of KM for children with CP.

      • KCI등재

        수종(數種)의 한약재(韓藥材)가 인체(人體) 암세포주(癌細胞柱)에 미치는 세포(細胞) 독성(毒性)

        정현우,Jeong, Hyeon-U 대한한방내과학회 1997 大韓韓方內科學會誌 Vol.18 No.1

        The purpose of this research was to investigate effect of water extract of Euphorbiae Pekinensis Radix and Moutan Cortex Radicis on the proliferation of human cancer cell-lines. The effects of Euphorbiae Pekinensis Radix and Moutan Cortex Radicis on the proliferation of A431, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay. The results were as follows; 1. In proliferation of A431, HeLa, MOLT-4 and K562 cell-lines, Euphorbiae Pekinensis Radix and Moutan Cortex Radicis inhibited the proliferation of K562 cells. 2. In the combined effect of Euphorbiae Pekinensis Radix and mitomycin C, Moutan Cortex Radicis and mitomycin C, all herbs stimulated the proliferation of MOL T-4 cells. 3. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis did not inhibited the proliferation of Balb/c 3T3 cells. 4. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of mouse thymocytes. 5. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of mouse splenocytes. 6. Euphorbiae Pekinensis Radix and Moutan Cortex Radicis stimulated the proliferation of human lymphocytes.

      • KCI등재

        재난적의료비, 의료비만의 문제인가 -중장기 입원으로 인한 근로소득 감소의 매개효과를 중심으로-

        정현우,양정연,차선화,이준협 한국보건경제정책학회 2019 보건경제와 정책연구 Vol.25 No.4

        The main focus of this study is to show that Catastrophic Health Expenditure (CHE) is not caused only by high copayments, but also the income reduced by the deterioration of health. This study examined the impact of mid-to-long-term hospitalization (MLTH) on the incidence of catastrophic medical expenses through the mediating effect on the reduction of earnings. The results of the analysis were as follows: First, the MLTH itself had a positive impact on the occurrence of CHE. Second, MLTH had a negative effect on earned income. Third, earned income was mediated by the effects of MLTH on CHE outbreaks. Although CHE is an indicator defined as the ratio between household income and health care costs, the critical minds of previous studies have focused on health care costs only. It is also important to note that the characteristics of CHE have serious health consequences, which can affect household incomes. As a policy, the view of expanding medical security should be extended to that of income security.

      • KCI등재

        죽력(竹瀝)이 T-lymphocytes 및 복강(腹腔) Macrophage에 미치는 영향(影響)

        정현우,강성용,한종현,이원석,오찬호,은재순,Jeong, Hyun-Woo,Kang, Sung-Yong,Han, Jong-Hyun,Lee, Won-Suk,Oh, Chan-Ho,Eun, Jae-Soon 대한한방내과학회 1997 大韓韓方內科學會誌 Vol.18 No.2

        The purpose of this research was to investigate effects of Bambusae Caulis in Liquamen(BCL) on T-lymphocytes and peritoneal macrophages in mice. The apoptosis and subpopulation of T-lymphocytes were tested using a flow cytometer. The phagocytic activity of mouse peritoneal macrophage was tested using a luminometer. Nitric oxide production was tested using a Griess reagents. BCL induced T-lymphocytes apoptosis. BCL increased $T_H$ cells population and decreased $T_C$ cells population of T-lymphocyte, but did not affect splenocytes subpopulation. BCL increased nitric oxide production and phagocytic activity of peritoneal macrophage in mice. These results suggest that BCL regulates the immune system in consequence of an increase in helper T cell population and macrophages activation.

      • KCI등재

        淸暈化痰湯加味方이 局所腦血流量 및 평균혈압에 미치는 실험적 연구(Ⅲ)

        정현우,노영호,김천중 대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.3

        Cheonghunhwadam-tang have been used in oriental medicine for many centuries as a therapeutic agent of vertigo by wind, fire and phlegm. CHT Gamypang(CTG) was CHT adding Aurantii Fructus(AF). The effects of CTG on the regional cerebral blood flow(rCBF) and mean arterial blood pressure(MABP) is not known. The mechanical Study of CTG on the cerebral hemodynamics is not known too. Therefore, purpose of this Study was to investigate effects of CTG on the rCBF and MABP, mechanism of CTG on the cerebral hemodynamics in rats. The changes of rCBF and BP was determinated by Laser-Doppler Flowmetry(LDF). The results were as follows ; CTG extract was significantly decreased rCBF in a dose-dependent, but the change of MABP was not shown. Pretreatment with propranolol(3㎎/㎏, i.v.) was significantly increased CTG(10 ㎎/㎏, i.v.) induced decrease of rCBF. Pretreatment with indomethacin(3㎎/㎏, i.v.) and methylene blue(10㎍/㎏, i.v.) were increased CTG induced of rCBF too. This results suggest that the mechanism of CTG is mediated by adrenergic β-receptor, guanylate cyclase and cyclooxygenase.

      • KCI등재

        Green Tea Encourages Growth of Akkermansia muciniphila

        정현우,김정기,김아영,조동현,이지혜,최진규,박미영,김완기 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.8

        Trillions of microorganisms reside in the hosts' gut. Since diverse activities of gut microbiota affect the hosts' health status, maintenance of gut microbiota is important for maintaining human health. Green tea (GT) has multiple beneficial effects on energy metabolism with antiobesity, antidiabetic, and hypolipidemic properties. As GT contains a large amount of bioactive ingredients (e.g., catechins), which can be metabolized by microorganisms, it would be feasible that consumption of GT may cause compositional changes in gut microbiota, and that the changes in gut microbiota would be associated with the beneficial effects of GT. In this study, we demonstrated that consumption of GT extract relieves high-fat diet-induced metabolic abnormalities. Interestingly, GT administration significantly encouraged the growth of Akkermansia muciniphila (Akkermansia), a beneficial microorganism to relieve obesity and related metabolic disorders. Finally, we found that epigallocatechin gallate is the component of GT that stimulates the growth of Akkermansia. According to these data, we propose that GT could be a prebiotic agent for Akkermansia to treat metabolic syndromes.

      • 信用狀 統一規則의 4次 改正

        鄭賢宇 釜山水産大學校 1985 論文集 Vol.35 No.-

        Uniform Customs and Practice for Documentary Credits (UCP) operated world-widely has been revised four times and the recent revision made in June, 1983 which came into effect on October 1, 1984. International Chamber of Commerce (I.C.C.; funded in 1919) draws up the rules on the documentary credits which are used to effect payment for goods, keeping up with major changes which affects international trade. UCP was established in 1933 with the support of United States. The position of America in international trade has become greater since World War 1 and they faced various disputes on credits over 1930s world depression. That's why U.S. welcomed the idea of uniforming the rules on credits. UCP, made up of General Rule, 5 parts, 49 articles, was not adopted at first by U.s. and U.K. They made some reservation for adoption. The reservations were made about charter party B/L, received B/L, Insurance Certificate, partial shipment. And so the established rule was mostly based on European principle. * * * UCP was revised first in 1951(effective January 1, 1952). This revision covered American references and made harmoney with the existing European principle. The countries adopting this rule increased to 77 countries and standard from of letter of credit was adopted. UCP was revised again in 1962(effective July 1, 1963) with UK adoption of this rule. The language of UCP was changed from French into English and UCP became world-wide except some communist countries (Red China). UK principle affected this rule, making it stricter, comprehensive, abstract. For example, the governing clause should be contained in L/C and UK contended that option clause(may) should be abolished. For the third time UCP was revised in 1974 (effective ON October 1, 1975) to keep up with the development of combined transport. The definition of combined transport and the acceptability of received B/L were made and clauses (except clause 41) were abolished. * * * The fourth and l test revision, adopted in June 1983 and become effective on October 1, 1984, supplemented the third revision mainly in the field of combined transport, also covering the change of payment method-stand-by L/C and deferred payment L/C. and more or less clause(±3%→±5%). The structure has been changed into 6 chapters, 55 articles. And the shipping documents are now called transport documents. The summing-up of the fourth revision in case of transport documents is as follows: -Copies are treated as originals. -Transport documents are divided into three kinds: 1) Transport documents excluding marine B/L, post certificate 2) Marine B/L 3) postCertificate -Division of the acceptability has been made: 1) will accept 2) will not reject, 3) will reject -Post certificate: accept and partial shipment possible with same certificate -In case of marine B/L: almost the same as the old rule: Combined Transport Documents: much change; Refer to the follwing table for the chaange and comparision between old rule and new rule: oldrule newrule form specify or accept as presented short from, blank endorsement issuer " " carrier or his agent freight forwarder and person locally qualified " indication of on-board on board or not indicated dispatch taking in charge, or on board "intended"(vessel,port) none not reject transhipment:definition reloading of the goods reloading of good and the conveyance(vessel) acceptability B/L for entire voyage B/L for the course of carriage Revision trend can be concluded as follows: 1) Keeping with the development of means of transportation and communication and other technologya; Clearer definition of combined transport and its document; accepting copies as originals 2) Realization of new types of transaction: stand-by L/C, deferred payment L/C, BWT, more er less clause 3)Compliance with other international rules: CIP, expected profit 4) Strict interpretation: option clause abolished; insertion of governing clauseRevision trends 1) 3) are desirable for the rules to be living and interlinking with other rules, but strict interpretation draws our attention because stricter interpretation will make L/C transaction strict, which will cause decrease in international trade. Therefore, clear guideline of rules and cooperation of the parties concerned are more desirable. If not, more service of the banks is required. And clearer definition of stand-by L/C is also required in terms of form, revocability, ect.

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