상명대학교 공과대학 수학교육 강화방안 연구

홍대기(Hong, Dae-Ki),조태경(Cho Tae-kyung),박병수(Park Byoung-soo) 한국산학기술학회 2008 한국산학기술학회논문지 Vol.9 No.5

최근 국내대학 전반에 걸쳐서 공과대학의 우수 지원자가 점차로 감소되고 있는 상황이며 고등학교 수학 교육과정의 부실화에 따른 신입생의 학력저하에 대한 우려 또한 제기되고 있다. 이러한 위기상황에 대응하여 상명대학교에서는 공학교육의 발전 및 혁신을 위해 공학교육 혁신센터를 운영하고 있다. 공학교육 혁신센터는 공학교육 혁신을 위한 장가계획의 일환으로 수학 분야의 교육 강화를 위한 여러 가지 방안을 논의하여 노출하고 있다. 본 논문에서는 상명대학교에서 논의하여 도출한 수학 교육 강화방안을 제시한다. 이러한 결과들은 상명대학교 공과대학과 유사한 환경에 처해있는 다른 학교들의 수학 교육 강화를 위한 참고자료로 활용될 수 있을 것이다. Recently, the number of applicants for the engineering college is gradually decreased all over the nation. Additionally, the concerns of fall of freshman mathematical ability are raised due to the incomplete high school education. Therefore, the local universities endeavor in order to improve the quality of mathematics education, and study the countermeasure against the crisis. As part of these efforts, Sang-Myung University founds the innovation center for engineering education. The center derives several ideas in order to enhance the mathematics education quality. In this paper, the enhancement plans for the mathematics education in Sang-Myung University are proposed. Results in this paper will be helpful for other university to enhance the mathematics education as reference materials.

소화효소가 Helicobacter pylori의 증식과 공포화독소 생성에 미치는 영향

홍대식,강경희,장명웅 고신대학교(의대) 고신대학교 의과대학 학술지 2001 고신대학교 의과대학 학술지 Vol.16 No.1

Background : Global high prevalence rate of Helicobacter pylori infection is well-known fact. However, a large discrepancies exist between the diagnostic data obtained by the PCR and culture method, because the coccoid form of H.pylori which represent the majority form in the biological samples are not viable in the standard BHI broth with 5% horse serum. The component parts of saliva and gastric juice acted as neither stimulator nor inhibitor to the growth of H.pylori remain unclear. Objective : The purpose of this study was to evaluate the influence of amylase, pepsin, mucin, and lysozyme on the growth and vacuolating toxin production and titer of H.pylori in vitro. Materials and Methods : H.pylori 13,39,46,59,72,94,98 and 125 strains were isolated from patients with gastric disease. The digestive enzymes were inoculated in the 5% horse serum-BHI broth following final concentration of amylase (A; 0.20ug/ml), pepsin (P; 0.25ug/ml), mucin (M; 2,5ug/ml), and lysozyme (L; 1.5ug/ml). The vacuolating toxin titers of the culture supernatant were evaluated in the monolayer culture of RK-13 cells. Results : The morphologic conversion from bacillary to horse-shoe to coccoid forms of H.pylori was observed in the BHI broth containing 5% horse serum on day 5 culture. Half of H.pylori was changed from bacillary to coccoidal form on day 7 culture, most population of H.pylori was changed to coccoidal form on day 10 culture, and almost all H.pylori was changed to coccoidal form on day 14 culture. The growth of H.pylori 72, and 94 strains was increased in BHI broth containing each enzyme such as amylase, pepsin, mucin and mixture of two or three enzymes on day 5 and 7 culture. The growth of H.pylori 94 strains was increased in BHI broth containing each enzyme such as amylase, pepsin, mucin, and mixture of two or three enzymes on day 10 and 14 culture. The vacuolating toxin production of H.pylori strains was not influenced by the addition of amylase, pepsin, mucin, and lysozye or mixture of two or three enzymes. The neutralization of vacuolating toxin of H.pylori was not affected by the addition of amylase, pepsin, mucin, and lysozyme or mixture of two or three enzymes. Conclusion : We found that coccoid forms of H.pylori were viable in the standard 5% horse serum BHI media in the presence of amylase, pepsin, mucin, and lysozyme. The present study demonstrates that gastric juice of the stomach supports the viability of H.pylori and that oral route of infection is a plausible hypothesis. This work also demonstrates that gastric environment may not provide a selective advantage for the toxigenic strains of H.pylori.

장기계류선박의 해양오염예방 대책에 관한 고찰

홍대환,강병용,최현규,이승환 해양환경안전학회 2023 해양환경안전학회 학술발표대회 논문집 Vol.2023 No.04

전기통신사업법상 금지행위에 대한 과징금 산정기준 개선방안

홍대식 경북대학교 IT와 법연구소 2011 IT와 법 연구 Vol.0 No.5

This article aims to suggest the improvement scheme of criteria for calculating administrative fines for prohibited activities under the Telecommunications Business Act of Korea by improving the components of the relevant turnover-based method or considering alternatives for it based on the economics-based idea. From the economic perspective, the main objective of the legal enforcement through administrative fines lies in deterring the violation of law by altering the economic incentives of the violators in a way that induces them to refrain from the prohibited activities comparing the expected profits with the expected costs to be imposed through monetary sanctions. Since harm-based method by which the amount of administrative fines is adjusted to a decline of social welfare caused by the violation seems to be more accurate method in establishing the optimal level of deterrence, it is recommended to revise the components of the relevant turnover-based method by incorporating such elements as corresponding to harm-based method rather than act-based method. In addition, the introduction of calculation formula developed through harm-based economic idea could be contemplated as a supplement to the relevant turnover-based method. Against this background, this article proposes concrete alternatives to improve the components of the relevant turnover-based method. Particularly, various ways of defining the concept and scope of the relevant service which has the effect of violation as its integral element are suggested with some comments. As for supplementary methods, the ways of introducing the formula for calculating a decline of other enterprises' profits as well as a decline of users' surplus based on the harm-based economic idea and taking practical account of the size of illegal gains are also provided. The table contrasting the current relevant part of the regulation with the suggestion will be illustrated as a conclusion.

Vitamin D3의 합성유도체인 Calcipotriol ( MC 903 ) 이 배양된 인체 각질형성세포 및 멜라닌세포의 성장에 미치는 영향에 관한 연구

홍대광(Dae Kwang Hong),윤태진(Tae Jin Yoon),김낙인(Nack In Kim),박재경(Jai Kyung Park),허충림(Choong Rim Haw) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.6

The cutaneous synthesis of vitamin D in response to ultraviolet radiation exposure is the most important factor in maintaining vitamin D balance in Man. The skin is not only the site of vitamin D synthesis, but also a target organ for calcitriol(1, 25-dihydroxy-vitamin D) which is naturally occuriag, hormonally active form of vitamin E. It is now known that calcitriol inhibits the proliferation of epidermal cells and induces her differentiation. In this study, epidermal keratinocytes and melanocytes were isilated from the neonatal foreskin, and were culturod using a MCDB 153 and modified TIC media, respectively. And then various concentratioris of calcipotriol(MC 903), a synthetic aralogue of calcitriol, were added to each culture. The effects of calcipotriol on the growth of human keratinocytes and melanocytes were investigated. The results were as follows : 1. The addition of calopotriol to human keratinocyte and melalocyte cultures inhibited their proliferation in a dosdependent manner. 2. Calcipotriol had no effects on the melanization process of the melanocyte. 3. Calcipotriol was found to inhibit the proliferation, however it induced the terminal differentiation of cultured keratinocytes, as judged by morphologicai changes. The decreased density of kerationcytes, The formation of cornified cells, and the cellular destruction in a concentration of 10 M of calcipotriol were observed. 4. By using the light atid the electron microscope, we observed that the epidermal thickness was decreased and terminal differentiation was facilitateir. Living Skin Equivalent (LSE) according to the increasing concentration of calcipotriol. A]i)parent cytotoxic effects were observed in 10 M, 10 M of calcipotriol. In summary, the above results indicate that the addition of calcipotriol to the in vitro culture system of human keratinocyte and melanocyte induces the biologic process of terminal differentiation of keratinocytes and inhibits proliferation of keratinoytes and melanocytes in a dose-dependent manner. (Kor J Dermatol 1992;30(6):811-823)

전기통신사업법상 금지행위에 대한 과징금 산정기준

홍대식(Dae Sik Hong) 서강대학교 법학연구소 2006 서강법학 Vol.8 No.-

대구경 관로 노후도평가 신뢰성 향상에 관한 연구

홍대성(Hong Dael Seong),김중훈(Kim Joong Hoon),유철상(Yoo Chul Sang),김응석(Kim Eung Seok),최병습(Choi Byung Sub) 대한토목학회 2009 대한토목학회 학술대회 Vol.2009 No.10

TiO2 광촉매와 UV LED를 이용한 접촉연소식 수소센서

홍대웅 ( Dae Ung Hong ),한치환 ( Chi Hwan Han ),한상도 ( Sang Do Han ),곽지혜 ( Ji Hye Gwak ),이상렬 ( Sang Yeol Lee ) 한국센서학회 2007 센서학회지 Vol.16 No.1

統一新羅 石佛臺座의 造形硏究 Ⅱ

洪大韓(Hong Dae Han) 한국문화사학회 2004 文化史學 Vol.0 No.21

Phase Plane상의 안정경계 및 횡력 포화경계를 이용한 차량 안정성 해석

홍대건(Daegun Hong),허건수(Kunsoo Huh),박장현(Jahng-hyon Park),조동일(Dong-il Cho) 한국자동차공학회 2004 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

It is known that the instability of a vehicle is caused by nonlinear characteristics of a tire and depends heavily on the rear tire force saturation. In this paper, the vehicle stability is analyzed using this phase plane method and this analysis is expanded to the 3-dimension including the steering angle. As a result, the 3-D stable boundary is constructed with respect to side slip angle, rate of side slip angle and steering angle. In the lane change maneuvers of a vehicle, the stable margin is monitored by comparing the trajectory of vehicle's side slip angle and steering angle with the 3-D stable boundary. This stable margin can be utilized as an index in order to estimate a vehicles' stability. Also, the lateral tire force saturation is analyzed and the saturation boundary is determined in the phase plane. It is confirmed that this saturation boundary is located inside of the stable boundary and the non-saturation region of the lateral tire force is smaller than the vehicle stable region.