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      • 가미귀비탕의 미백효과에 관한 연구

        박호순,김혜정,김윤범,Park, Ho-Soon,Kim,Hye-Jung,Kim, Yoon-Bum 대한한의진단학회 2004 大韓韓醫診斷學會誌 Vol.17 No.2

        Objective: This study was performed to investigate the depigmentation effects of the extracts of Kamikwibi-Tang. Methods Inhibition of tyrosinase activity, melanin production & cell viability in cultured B16 melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide were measured. Results: The extracts of Kamikwibi-Tang did not have any inhibitory effects on tyrosinase activity and did not show any inhibitory effects on melanin production in melanoma cells and also did not have any inhibitory effects on UV screen. But the extracts showed high cytoprotective effects on PC12 cells injured by hydrogen peroxide. Conclusion : These results suggest that Kamikwibi-Tang indrectly inhibits melanin biosynthesis which is involved in hyperpigmentation and could be used as a whitening agent for the skin.

      • KCI등재

        침술요법과 부항요법을 사용한 안면경련 치험 3례 -근막동통증후군(Myofascial syndrome: MPS)을 위주로 하여 치료함-

        박호순,김윤범,Park, Ho-soon,Kim, Yoon-bum 대한한방안이비인후피부과학회 2003 한방안이비인후피부과학회지 Vol.16 No.3

        In the treatment of hemifacial spasm, the operative methods, such as neurovascular decompression, rhizotomy etc. are the most efficacious therapy on its control. But, due to some side effects and complication, pharmacotherapy has been the first attempted by first intention of hemifacial spasm. The carbamazepine is the most commonly used agent, however it is often inefficacious in some cases, and attenuates as the time passes, engages in some symptoms, such as dizziness, nausea, vomiting, and causes an aplastic anemia, it has many deficiencies in becoming the first intention. Acupuncture is a simple, effective and conservative spasm control modality. It is so simple to use in hemifacial spasm. We had observed 3 cases of hemifacial spasm which were treated by acupuncture in Oriental clinic recently. We reported these cases and reviewed related literatures briefly. The results of treatment are as follows; The clinical conditions of spasm intensity was improved after the therapy. These results suggest that acupuncture and negative therapy be effective as the first intention in healing hemifacial spasm.

      • KCI등재

        六味地黃湯加味方으로 치료한 소아기 아토피 피부염의 한방 치험 5례

        박호순,김윤범,Park, Ho-soon,Kim, Yoon-bum 대한한방안이비인후피부과학회 2003 한방안이비인후피부과학회지 Vol.16 No.2

        Introduction: Atopic dermatitis is chronic eczematous recurrent disease of skin and till now its mechanism is not cleary known. It is related to a family history of atopic disease. It has severe itching and it causes eczema secondarily. Atopic dermatitis has mostly severe symptoms and progresses to chronic relapsing. Objectives: The purpose of this study was to estimate the efficacy of herb- medicine treatment on atopic dermatitis. Subjects: 1 treated 5 patients who visited Chungbalsan Kyunghee oriental medical clinic with atopic dermatitis from September, 2001 to October, 2002 partiticipated in the study and were observed for over 2 months. Methods: I treated them with herb-medication and external application. (Atopione)

      • KCI등재SCOPUS

        MODIS 적외 자료를 이용한 동아시아 지역의 총가강수량 산출

        박호순 ( Ho Sun Park ),손병주 ( Byung Ju Sohn ),정의석 ( Eul Seok Chung ) 대한원격탐사학회 2008 대한원격탐사학회지 Vol.24 No.4

        In this study the retrieval algorithms have been developed to retrieve total precipitable water (TPW) from Terra/Aqua Moderate Resolution Imaging Spectroradiometer (MODIS) infrared measurements using a physical iterative retrieval method and a split-window technique over East Asia. Retrieved results from these algorithms were validated against Defense Meteorological Satellite Program (DMSP) Special Sensor Microwave/Imager (SSM/I) over ocean and radiosonde observation over land and were analyzed for investigating the key factors affecting the accuracy of results and physical processes of retrieval methods. Atmospheric profiles from Regional Data Assimilation and Prediction System (RDAPS), which produces analysis and prediction field of atmospheric variables over East Asia, were used as first-guess profiles for the physical retrieval algorithm. We used RTTOV-7 radiative transfer model to calculate the upwelling radiance at the top of the atmosphere. For the split-window technique, regression coefficients were obtained by relating the calculated brightness temperature to the paired radiosonde-estimated TPW. Physically retrieved TPWs were validated against SSM/I and radiosonde observations for 14 cases in August and December 2004 and results showed that the physical method improves the accuracy of TPW with smaller bias in comparison to TPWs of RDAPS data, MODIS products, and TPWs from split-window technique. Although physical iterative retrieval can reduce the bias of first-guess profiles and bring in more accurate TPWs, the retrieved results show the dependency upon initial guess fields. It is thought that the dependency is due to the fact that the water vapor absorption channels used in this study may not reflect moisture features in particular near surface.

      • KCI등재

        의약분업 전,후 병원재무구조 평가

        박호순 ( Park Ho Sun ),류규수 ( Lyu Gyu Su ),이창은 ( Lee Chang Eun ) 한국병원경영학회 2003 병원경영학회지 Vol.8 No.3

        This study is aimed at evaluating the financial structure of hospitals before and after the separation of prescription and drug dispensing policy started to be implemented in July 2000 and at making a suitable hospital managerial strategy through the verification of the factors which have effect on their profitability. This study investigated the hospitals which have passed the accredition review to be designated as a accredited training hospital each year for three years from 1999 to 2001. Those hospitals were selected from members of the Korea Hospital Association. 106 hospitals were targeted for analysis except for the hospitals whose financial statements and managerial performance were not reported faithfully. The financial indicators used in this study were stability indicators(liability to total assets, ratio of debt to fund balance, fixed ratio), liquidity indicators(current ratio, quick ratio), activity indicators(total assets turnover, fixed assets turnover), profitability indicators (net profit to total assets, net profit to net worth, operating margin), and operating expenses to patient revenues indicators( (drug and supplies costs/payroll/ overhead expenses 1. The result of this study are as follows: First, the analysis of the increase of loss-malung hospitals before and after The separation of prescription and drug dispensing policy shows that the number of loss-malung hospitals increase after the separation(22.6% before the separation; 31.1% after the separation). However, there was no significant statistical difference. Second, the analysis of operating expenses to patient revenues indicators showed that the ratio of drug and supplies cost became lower in all hospitals but the ratio of payroll/overhead expenses became higher. Additionally, the factor which have the greatest effect on profitability was operating expenses to patient revenues indicators (drug and supplies costs/payroll/overhead expenses). Third, the analysis of managerial performance by four types of loss-loss, loss-profit, profit-loss and profit-profit compared the results before the separation with those after the separation revealed as follows: Reliance on liability to total assets became higher in the profit-loss type(56.2%→66.4%), lower in the loss-profit type(82.7%→74.5%). Total assets turnover became higher in the profit-profit type(1.3->1.5), but lower in the loss-profit type(0.8→0.7). Operating margin decreased to minus 5.9% from 4.3% in the profit-loss type, but increased to 7.2% from minus 7.804 in the loss-profit type. Forth, operating expenses to revenues indicators showed that the increase of payroll was the biggest in the profit-loss type(39.25%→49.9%) and that overhead cost decreased in the loss-profit type but that rather increased in other types.

      • KCI등재

        디지털 트윈 기반 문화재 건축물 3D 모델링 및 UAV 아카이브 구축에 관한 연구

        손혜연,박호순 한국기초조형학회 2024 기초조형학연구 Vol.25 No.2

        The purpose of this study is to prepare a digital archive plan of buildings through 3D modeling of cultural properties based on the digital twin. The concept of digital archives was examined, and recent cases of archives applying 3D digital technology were analyzed. In addition, examples of digital cultural heritage contents in domestic museums and digital cultural heritage policies and directions abroad were examined. This summarizes the contents for the construction of the cultural heritage building archive. First, it is necessary to acquire high-quality 3D data to secure good data as it is. Second, the process of digitization for preserving and restoring existing cultural properties should be made possible through various win-win cooperation such as public-private cooperation, and should be produced to ensure continuous compatibility and storage. Third, active participation of local administration and continuous participation of experts and citizens to bring out the resources of storytelling should be possible. Fourth, applications to digitization and ultra-realistic technology by applying the geographic information system are being made.As a strategy for building a digital archive of cultural properties, 3D modeling was implemented for the construction of a digital archive using UAV. The conclusion is as follows. 1) It was confirmed that most of the development policies and projects for the digitization of architectural cultural heritage included buildings. 2) Digitalization is in progress in recording cultural heritage around the world, and it can be seen that strategy development is taking place at the national level. 3) Digitalization technology follows a contactless digital data acquisition method such as photogrammetry, and it was found that the implementation of 3D modeling based on PCD data is a strategy to maintain the completeness of the digital twin as a method for acquiring high-resolution data. 4) Digital techniques are currently being explored for shared experiences and dissemination, ranging from immersive experiences to media art, with expectations for their widespread adoption in the emerging metaverse world in the future.

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