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      • 젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

        이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

        Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

      • KCI등재

        1930년대 후반 장편소설론 및 로만 개조론 연구

        주지영(Joo, Ji?young) 한국비평문학회 2012 批評文學 Vol.- No.46

        Study on full?length novel in the late 1930"s is not free from the influence of the socialist realism and the imperialism of the time. They have a difficult problem that is impossible to recognize of the real objectivity and totality. Although discussion of full?length novel reinforced the quality of literary of the time. Besides, "alteration of novel" is not conscious discussion. Discussion of full?length novel are summarized four level. First, there are launched a bitter diatribe against that the serial story in a newspaper has be inclinable to its popularization. Second, there are discussion that make a comparative study on the Joseon during Japanese colonial era full?length novel and the Western full?length novel. Third, there are discussion that make a comparative study on short story and full?length novel. Fourth, there are discussion that full?length navel are now facing a serious crisis through a defunct newspaper. And there are discussion about coming up with a remedy. The alteration of novel appertain to second level. That is a kind of literary creative methodology. Im?hwa insist on "a serious novel" that have the creation character being the result of its behavior and harmony between the subject and the object. He insist that overcome contradiction caused by feudalism at the same time Imperialism. Kim?Namchoen insist on "novel of cultural landscape" and "novel of family history", "novel of chronicle". His argument is fluctuated with debating with Im?Hwa. First time, he intent to reconstruction the subject through accusing oneself. Second time, he intent to confluence the subject and the object. In conclusion, it is a significant fact that the debate on full?length novel and alteration of novel is considered with autochthonism and particularity literary theories in the late 1930"s.

      • 서울의 PPNG 발생 빈도(1991-1992)

        김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1

        The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.

      • KCI등재

        식품영양학 전공자를 위한 인턴십 교육 프로그램 개선방안

        주나미,윤지영,김옥선,정현아,박상현,고영주,조기원 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1

        This study was conducted to evaluate the effect of current dietetic internship program. The survey sample was dietetic practitioners who were charged with a training for dietetic students. The questionnaire requested information about demographic information, experience of guidance for the dietetic student, self evaluation as trainer, fortification items in university education, and difficulties of the internship program. Data was analyzed using SAS for windows(version 6.12), Descriptive statistics were used such as means. standard deviations. frequency distribution and percentages. Comparison of mean differences was analyzed using t-test and ANOVA. Participants identified how effective the current internship program was. Result indicated that the effectiveness was not high(2.81), and under 29 years old age group, under 6 years work experience group. and contracted foodservice group had positive opinion of the program significantly. Under 29 years old age group, evaluated themselves as a good trainer. The results revealed that respondents wanted to be fortified the practical training courses in school curriculum.

      • KCI등재
      • KCI등재후보

        발육중인 생쥐 하악 과두에서 연골 및 골의 특이 유전자 발현

        지국섭,윤영주,박주철,김광원 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.2

        하악과두 연골이 발생하고 분화하는 과정에서 나타내는 특성을 규명하기 위하여, 발생 16, 18일과 출생 1일, 5일, 10일, 20일 및 30일 후의 ICR생쥐의 하악과두를 형태학적으로 분석하고, 생쥐 Ⅰ형, Ⅱ형, X형 교원질, Indian hedgehog(IHH) 및 BMP-4 등의 mRNA 발현을 in-situ hybridization 방법으로 연구하였다. 1. 생쥐 Ⅰ형 및 Ⅱ형 교원질 mRNA는 하악과두의 발생 및 성장과정에서 모두 발현되었다. Ⅰ형 교원질 mRNA는 휴지층과 증식층의 상부에서 관찰된 반면 Ⅱ형 교원질은 휴지층과 증식층 그리고 비대연골층의 상부에서 관찰되었다. 2. 하악과두 연골은 성장에 따라 비대연골층이 계속 증가하는 소견을 보였으며, 비대 연골층의 세포들은 특징적으로 X형 교원질 mRNA의 발현을 보였다. 3. BMP-4 mRNA는 하악과두 연골 원기와 골화중인 하악골체에서 모두 발현되었다. 4. IHH mRNA는 하악과두의 발생과정에서 증식 연골층의 하부와 비대연골층의 상부에서 선택적으로 관찰되었다. It has not been elucidated whether the initiation of condylar development of the mandible is related with the periosteum of the mandible, or if it derives from a separate programmed blastema not related with the mandible. Also, although the mandibular condylar cartilage is known to promote growth, few studies have dealt with molecular-biologic mechanisms such as the expression of specific genes according to the differentiation of the mandibular condyle. To elucidate the unique cellular characteristics, development, and differentiation process of the mandibular condyle, an examination of expressions of genes characteristic of cartilage and bone were carried out using RT-PCR and mRNA in situ hybridization. 1. Type?collagen mRNA was detected with type Ⅱ collagen mRNA in the differentiation and growth process of the cartilage of the mandibular condyle. Type Ⅱ collagen mRNA was demonstrated in the whole resting and upper part of the proliferative zone, whereas type Ⅱ collgen mRNA was observed in the resting, proliferative and upper hypertrophic cartilage zone of the mandibular condyle. 2. The condylar cartilage rapidly increased in size due to the accumulation of hypertrophic chondrocytes as characterized by the expression of type Ⅱ collagen mRNA during postnatal development. 3. BMP-4 mRNA was present in the anlage of the future condylar process and also in the ossifying mandibular body. 4. IHH mRNA was limited exclusively to the lower part of the proliferative zone and the upper part of the hypertrophic cartilage zone during condylar development. These findings were different from those in the growth-plate cartilage of the long bone, indicating a characteristic feature of the differentiation of the chondrocytes in the condylar cartilage present in prenatal and postnatal development. Furthermore, it was also suggested that chondroblasts of condylar cartilage rapidly differentiate into hypertrophic chondrocytes with increased functional Load force such as muscle activity and mastication.

      • KCI등재

        소금 종류 및 농도에 따른 김치 효모균의 생육특성

        한영숙,권민경,현영희,송주은,오지영 동아시아식생활학회 2001 동아시아식생활학회지 Vol.11 No.5

        Effects of various types of salts (commercial low salt, sea salt, refined salt, and bamboo salt) and concentrations (0, 3.0 and 5.0%) on the growth of yeasts isolated from Kimchi were investigated. The isolated yeasts used in the study are as follows: Saccharomyces cerevisiae. Sporobolomyces albo-rubescens, Issatchenkia orientalis, Cryptococcus luteolous, Ustilago maydis. Candida humilis, Pichia onychis, Cadida nitratophila, and Pichia jadinii. The growths of the yeasts were inhibited against each salt concentration. The growths of Candida sp. isolated from the later stage of fermentation was strongly inhibited against 5% concentration of salt. On the other hand the induction phase of Issatchenkia orientalis isolated at the early stage of fermentation was the quickest among all the tested yeasts. Among the salts. bamoo salt was found to be strongest inhibitor of, the growth of yeasts.

      • 무용전공 여대생들의 체중조절 관심도와 섭취식품 기호도 조사연구

        황지영,신호주 명지대학교 교육대학원 1998 敎育大學院 論叢 Vol.1 No.-

        The objective of the current study consists in inquiring into how Korean traditional dance and ballet majors are interested in their weight control and what preference they have for ingestion, to articulately elucidate physical management for weight control and dietary habits in those college students who major in dance. Analysis of differences between the two groups revealed findings, as follows; 1. Both the Korean traditional dance majors group and ballet majors group take the time of physical weight control fifteen days ahead of the date of their exhibition or performance, by 64.5%. The Korean traditional dance group show the period of the most interest in weight control while studying in senior high school by 61.0%, whereas the ballet major group by 51.0%. Concurrently with this they were most affected by school lessons by 45.0% or mass communication by 30.0%, and it was carried out by their own judgment by 76.5%. The number of students who think they are 'fat' wish a loss of weight by 55.0% in the Korean traditional dance majors group, and by 43.0% in the ballet majors group. For the techiques of physical weight reduction, the employ 'reduction of the quantity of food intake' by 54.5%, and 'an increase of the quantity of motion' by 20.0%, which indicates that diet and exercise are considered the most effective method. 2. They generally prefer two meals a day, one meal less than the normal number of meals, three time. The lenth of mealtime reveals '10 to 20 minute', by 64.0% in Korean traditional dance group, and by '20 to 30' by 60.0% in the ballet majors gorup, which indicates a longer time in the former group than in the latter. Almost all the dance majors eat snacks by 98.5%, and the reason for that gives the highest responses in 'habitually' by 37.0%. Most of dance majors represent irregularity in taking meals, and the reason for going without a meal is ascribed to 'no time to eat' or 'weight control'. Furthermore, mooted points on dietary habits are most reflected from 'irregular mealtime' by 39.0%, and 'the ingestion of finished food and instant food' by 30.5%. From these, they are well aware of the need to improve. 3. The highest preference for food is put on the generalized food, whereas food on a low level of recognition gives a low level of preference for that food. In general, fruit gives a high preference, for the foods that dance majors abhor include animal liver, bacon, dried slices of seasoned white bait, margarine, soybean milk, jam, etc. But a great preference is shown from yofle(yogurt) by forming 83.0%.

      • 수술로 호전되지 않은 췌장 농양을 내시경 치료로 완치한 1 예

        서희영;전태주;김선영;강미선;허란;박지영;서동대;오태훈 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-

        Necrotizing pancreatitis develops in about 10-20% of patients with acute pancreatitis, and pancreatic abscesses develop in 3% of them. The mortality of pancreatic abscess has been reported up to 40% in one study. Recently, there are several reports that show good results with n on-surgical therapy, such as percutaneous drainage and endoscopic drainage, but if the non-surgical drainage fails, surgical therapy are recommended. However, there is no definite therapeutic method which is suggested yet so far after the failure of the surgical drainage. So we report the case in which we experienced successful treatment of pancreatic abscess by endoscopic removal of necrotic tissue through the gastrocystostomy, after the failure of the surgical debridement and internal drainage through gastrocystostomy.

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