대구 의류상설할인타운 이용 소비자 구매행동 분석

金貞援,李盛根 慶一大學校 1999 論文集 Vol.16 No.4

The purpose of this study was to analyze the purchasing behavior related factors of clothing outlet store user. The sample consisted of 160 of clothing outlet store user in Daegu. Frequency, X2-test, cluster Analysis, MANOVA, ANOVA and multiple range test were used to analyze the sample. The results of this study were as follows : 1) The largest sample were as follows : unmarried female, college and highschool student of twenties, 101-200 thousand won for salaries. 2) The factors of purchasing behavior were classified into 7 factors, value orientaion via price, store image orientation, information seeking, low price orientation serivce, advertising. 3) There were significant differences found between Attitude on fashion sense, salesperson, display, price, satisfaction of outlet store in their purchasing behavior factors : service, value orientaton via price, information seeking, low price orientation. 4) There were significant differences found between demorgraphy characteristics(sex, age, education, job, income, transportation) in their purchasing behavior factors : ( store image, service, information seeking, low price orientation).

단방성 법랑모세포증 환아에 대한 증례 보고

최서정,박호원,김성민 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.3

단방성 법랑모세포종(Unicystic ameloblastoma)은 임상적, 방사선적 및 병리학적 소견과 치료방법 등이 법랑모세포종과 구별되어 따로 분류된 질환이다. 임상적, 방사선적으로는 치성낭종의 소견을 보이는 단방성 병소이며 조직학적으로 낭종의 소견과 함께 법랑모세포종의 소견을 보인다. 하악 구치부에 호발하며 악골에 무통성 종창을 야기할 수 있으나 대개는 무증상인 경우가 많고 대부분 미맹출치 치관을 둘러싼 방사선 투과성 병소로 나타나며 방사선적으로 함치성낭(dentigerous cyst)이나 잔류낭(residual cyst)과 유사하다. 조직학적으로 낭종상피의 법랑모세포종성 변화(luminal type), 낭종강 내 종양결절의 돌출(intraluminal type), 결합조직 내로 법랑모세포종 세포의 증식(mural type)등의 소견을 보인다. 본 증례는 좌측 안면부 종창을 주소로 내원한 8세 남자 환아에서 임상적, 방사선적 검사 후 낭종의 완전 적출술(enucle-ation)및 장골이식(iliac bone graft)을 시행하였으며 생검을 통해 단방성 법랑모세포종이라 확진되었고 양호한 치료 결과를 얻었기에 이에 보고하는 바이다. The unicystic ameloblastoma deserves separate consideration on the basis if its clinical, radiologic, and patho-logic features and its response to treatment. It refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst, but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity. The lesion is most commonly found on the mandible posterior area, and often asympto-matic, although large lesions may cause a painless swelling of the jaws. The lesion typically appears as a cir-cumscribed radiolucency that surrounds the crown of an unerupted molar. These are usually considered to be a dentigerous, residual cyst on the relationship of the lesion to teeth in the area. These are usually considered to be a dentigerous, residual cyst on the relationship of the lesion to teeth in the area. Three histopathologic variants of unicystic ameloblastoma may be seen. 1) Luminal type, 2) Intraluminal type, 3) Mural type. In this case, these tumor was treated as cysts by enucleation with iliac bone graft, and the diagnosis of ameloblastoma is made after microscopic examination of the presumed cyst.

지역사회에서 형성된 사회적 지지와 근로자의 사회심리적 스트레스간의 관련성

임화영,김형수,최영환,장성훈,이건세,정최경희,오원기,최재욱,정춘화 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4

Objective: This study was performed to examine the relationship between community-based social support and psychosocial distress in workers. Methods: The study subjects were 596 workers recruited from 11 companies in Chungju city. A structured questionnaire was used to assess sociodemographics, health-related behaviors, job characteristics, job stress, work-based social support, community-based social support and level of psychosocial distress. Results: Hierarchical multiple regression analysis showed that workers with no chronic disease, exercise and sufficient sleep had a higher score of psychosocial distress than those with chronic disease, no exercise, and not enough sleep. Coworker's work-based social support and community-based social support were negatively associated with psychosocial distress. The R square value of total independent variables on psychosocial distress was 0.409, and that of community-based social support on psychosocial distress was 0.052. Conclusion: This study showed that community-based social support served as a protective factor against psychosocial distress in some workers. We recommend the establishment of a worksite stress reduction program in occupational level as well as community-based social support.

소규모 제조업에서 재해발생과 사업장 특성간의 관련성 분석

이건세,김형수,,장성훈,정최경희,오원기,최재욱,이관형,오지영 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 소규모 제조업 사업장의 재해 발생 유무에 따른 사업장 조직 특성을 비교하여 재해 발생과 관련된 요인을 사업장 수준에서 파악하고자 하였다. 방법: 한국산업안전공단이 실시한 2004년도 산업안전 보건 동향조사 자료 중 5인 이상 50인 미만 제조업 1,886개 사업장(가중치를 부여하여 추정한 모집단 사업장은 65,921개)의 재해(산재 및 공상, 경상 포함) 발생 여부와 사업장의 조직 특성(일반적 특성, 고용특성 및 산업안전보건 특성)간 다변량 분석을, 사업장의 일반적 특성은 지역, 산업형태, 업종 등이며, 고용특성은 전체 근로자중에서 생산직 근로자의 분포, 여성근로자의 분포, 1주일 평균 근로시간, 교대근무 등이며, 산업안전보건 특성은 안전관리자/보건관리자의 선임형태, 산업안전보건위원회, 노동조합, 매월 정기안전보건교육시간, 안전보건관리 규정, 안전보건활동 점수, 안전문화 점수 등이다. 결과: 다변량 분석결과 재해가 발생한 사업장이 갖는 특성은 다음과 같았다. 첫째, 사업장의 일반적 특성에서 지역별로는 경인권에 비해 전라권, 산업형태 면에서 원청에 비해 사외협력업체, 업종별로는 전자부품/통신에 비해 코크스/석유정제업, 목재/나무제품업, 음식료품, 조립 금속제품에서 위험도가 높았다. 둘째, 사업장의 고용 특성에서는 전체 구성원 중에서 생산직 근로자가 증가할수록 재해발생 사업장이 유의하게 증가하였으며, 여성근로자의 증가할수록 재해발생 사업장이 유의하게 감소하였다. 주당 근무시간이 증가할수록 재해 발생 사업장이 유의하게 증가하였으며, 교대 근무와 사업장의 재해발생과는 유의한 관련성이 없었다. 셋째, 사업장의 산업안전보건 특성에서는 안전관리자가 전임으로 근무할수록, 산안전보건위원회가 활발히 활동할수록, 노동조합이 설립될수록, 안전보건규정이 갖추어지지 않을수록, 정기보건교육시간이 많을수록, 안전문화수준이 낮을수록 재해발생 사업장이 유의하게 증가하였다. 결론: 소규모제조업에서 사업장의 조직 특성에 따라 사업장 재해율이 다름을 확인할 수 있었으며, 이는 산업재해의 예방을 위해서는 근로자 요인이외에도 사업장 수준에서의 관련요인에 대한 접근이 필요함을 의미한다. Objective: This study evaluated the relationship between injury occurrence and workplace organization in small-sized, manufacturing factories in Korea. Methods: Using data from the 2004 Occupational Safety and Health Survey in Korea, this study compared workplace organizational factors (general characteristics, employee characteristics and health and safety characteristics) with injury occurrence of 1,866 small-sized, manufacturing factories (65,921 population factories after weighting). General characteristics of factories comprised location, type and classification of industry. Employee characteristics comprised proportion of manual workers and female workers, average working hours per week and shiftwork. Health and safety characteristics comprised type of safety and health manager, committee for occupational safety and health, labor union, health and safety regulation, monthly health and safety training time, score of health and safety activity and score of safety culture. Results: The following characteristics of injury-occurrence in small-sized, manufacturing factories were determined by multivariate analysis. In terms of general characteristics, the risk of injury-occurrence was higher in Jeolla area than Gyeongin area in outside associate than other enterprises and in coke, refined petroleum products and nuclear fuel, wood and products of wood, food products and beverages and fabricated metal products, except machinery and furniture industries than television and communication equipment and apparatus industries. In terms of employee characteristics, injury-occurrence significantly increased in factories with greater proportion of manual worker and with a higher rate of working hours per week. But significantly decreased in factories with a higher proportion of female workers. In terms of health and safety characteristics, injury-occurrence significantly increased in factories with a self-appointed safety manager, with unorganized union, with a more active committee for occupational safety and health, with unimplemented health and safety regulation, with longer monthly safety and health training time, and with a lower score of safety culture. Conclusions: This study demonstrated that several factors of workplace organization were significantly related with injury-occurrence in factories. These findings are supposed to raise the need for making effort in workplace organization to improve injury prevention.

급성 진행형 국소 신경학적 증상을 보인 쯔쯔가무시병 1예에서 고용량 스테로이드의 사용

최현철,위성헌,이소연,김상일,박성경,정연주,정소령,전정수,강문원 대한감염학회 2002 감염 Vol.34 No.6

Level of Alcohol Consumption and Risk of Liver Cirrhosis Incidence among Men: A Meta-Analysis

( Soung Won Jeong ),( Ki Tae Suk ),( Jung Han Kim ),( Hye Kyung Jung ),( Yeong Sook Yoon ),( Seong Ho Yoo ),( Da Sol Kim ),( Ein Soon Shin ),( June Sung Lee ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Aims: The amount and duration of alcohol consumption are closely associated with cirrhosis. The aim of this study is to identify the incidence risk of liver cirrhosis according to the level of alcohol consumption Methods: We searched 4 Korean (KoreaMed, Kmbase, RISS, NDSL) and 5 global databases (Cochrane, Embase, PubMed, PsycINFO, NDSL). 240 studies assessed for full-text eligibility and data from 3 community based cohort studies were included in the meta-analysis. 2 studies did not provide any appropriate data for meta-analysis. A meta-analysis (generic inverse variance method and fixed model) include sub-group analysis and sensitivity analysis performed using Cochrane’s RevMan5.3 software. The Newcastle-Ottawa scale was used to evaluate the methodologic quality. Level of alcohol consumption was defined such as Low or Light (0.01-10.0 g/day), Light to Moderate (10.1-20.0 g/day), Moderate (20.1-40.0 g/day), Moderate to High (40.1-60.0 g/day), High or Heavy (60.1-120.0 g/day), Very High (>120.0 g/day). Results: Compared to light drinkers, the relative risks (RR) for liver cirrhosis incidence were as follows: 1.57 (95% CI: 1.17-2.09) I2=84% and 2.33(1.62-3.35) I2=0% sensitivity analysis for light to moderate, 3.23 (95% CI: 2.43-4.31) for moderate, 10.58 (95% CI: 7.75-14.44) moderate to high, 22.29 (95% CI: 16.15-30.77) high or heavy and 35.03 (95% CI: 23.27-52.74) very high drinkers. Age group 41-65 years showed a significant risk (RR 2.33, 95% CI: 1.52-3.57) while all age group did not show a significant risk (RR 1.13, 95% CI: 0.77-1.66) under sub-group analysis. Conclusions: There was significant association between incidence of liver cirrhosis and amount of alcohol consumption among men. Also, older age group showed higher incidence of liver cirrhosis comparing with all age group.

The Impact of Kidney Dysfunction on Mortality in Cirrhotic Patients with Acute Deterioration

( Soung Won Jeong ),( Tae Yeob Kim ),( Eileen L. Yoon ),( Do Seon Song ),( Hee Yeon Kim ),( Chang Wook Kim ),( Young Kul Jung ),( Dong Hyun Sinn ),( Sang Gyune Kim ),( Jae Young Jang ),( Won Kim ),( H 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

Aims: This study aimed to investigate short-term mortality and associated factors in cirrhotic patients with kidney dysfunction and acute deterioration. Methods: Of the 1204 cirrhotic patients experienced acute deterioration without kidney failure (defined as serum creatinine level of 2 mg/dL or above), 1094 patients (male 815, mean age 55.8 years) were retrospective consecutively collected during 2013. Kidney dysfunction was defined by serum creatinine levels from 1.2 to 1.9 mg/dL at admission based on retrospective KACLiF [Korean Acute-on-Chronic Liver Failure (ACLF)] study. Baseline characteristics and short-term mortality according to the presence of kidney dysfucntion were analyzed. Independent risk factors for 90-day mortality in patients with kidney dysfunction were obtained by multiple logistic regression. Results: The prevalence of kidney dysfunction was 19.2% (210/1094). The 28-day and 90-day mortality were higher in patients with kidney dysfunction than in those without kidney dysfunction (12.4% vs. 4.4%, P < 0.001; 19.0% vs. 8.5%, P < 0.001, respectively). Eighty percent (32/40) of non-survivor was associated with the presence of ACLF and 18 out of 32 patients (56.2%) were ACLF development after admission. In multiple logistic regression, low albumin level (0.1 mg/dL increase, OR 0.90, 95% CI 0.81-0.99, P = 0.033) and the presence of ACLF (at admission, HR 11.4, 95% CI 3.8-33.6, P < 0.001; after admission, HR 30.8, 95% CI 9.9-95.8, P < 0.001) had independent factors of 90-day mortality. Especially, ACLF experience of grade 2 or above had higher mortality than grade 1 ACLF (P < 0.001). Conclusions: In cirrhotic patients without kidney failure, kidney dysfunction with acute deterioration had a substantial mortality. To improve the mortality, it is necessary to endeavor to recognize the early renal dysfunction and to prevent additional organ failure and the progression of ACLF.

만성 C형간염에서 페그인터페론과 리바비린의 병합치료 시 지속바이러스반응에 대한 순응도의 효과

정승원 ( Soung Won Jeong ),김진동 ( Jin Dong Kim ),우현영 ( Hyun Young Woo ),유찬란 ( Chan Ran You ),이승원 ( Sung Won Lee ),송명준 ( Myeong Jun Song ),장정원 ( Jung Won Jang ),배시현 ( Si Hyun Bae ),최종영 ( Jong Young Choi ) 대한간학회 2009 Clinical and Molecular Hepatology(대한간학회지) Vol.15 No.3

목적: 만성 C형간염에서 페그인터페론과 리바비린 병합요법 치료 시 지속바이러스반응에 영향을 미치는 다양한 예측인자들이 알려져 있지만, 치료 순응도의 효과에 대해서는 구체적으로 밝혀져 있지 않다. 본 연구에서는 지속바이러스반응에 대한 치료순응도의 효과를 조사하였다. 대상과 방법: 페그인터페론 또는 리바비린 치료를 받은 만성 C형 간염 환자 122명 중에서 페그인터페론과 리바비린 병합치료를 받은 92명의 환자를 후향적으로 분석하였다. 환자들은 유전자 1형과 비1형을 치료 프로토콜에 따라서 각각 3그룹으로 분류하였다. 그룹 1은 80% 이상의 페그인터페론 및 리바비린 용량으로 80% 이상의 치료 기간 동안 치료받은 환자들이고, 그룹 2는 60% 미만의 페그인터페론 및 리바비린의 용량으로 60%미만의 기간 동안 치료받은 환자들이며 그리고 그룹 3은 이 두 그룹에 포함되지 않은 모든 환자들로 분류하였다. 결과: 치료 순응도가 달랐던 세 그룹 사이에 초기바이러스반응(early virologic response: EVR), 치료종료반응(end of treatment response: ETR) 그리고 지속바이러스반응(sustained virologic response: SVR)이 각각 의미있는 차이를 보였다. 유전자 1형 그룹들의 SVR률은 그룹 1이 86.7%, 그룹 2가 26.7% 그리고 그룹 3이 66.7%였다(P=0.003). 유전자 비1형 그룹들의 SVR은 그룹 1이 100%, 그룹 2가 16.7% 그리고 그룹 3이 88.9%였다(P<0.001). 결론: 치료 순응도는 SVR에 도달하는 데 있어서 결정적인 역할을 하며, 치료 순응도를 높이기 위한 여러 가지 지지요법들이 전체적인 SVR률을 높일 것이다. Background/Aims: Various predictive factors for peginterferon alpha and ribavirin therapy in chronic hepatitis C have been reported, but the effect of adherence to therapy has not been established. We investigated how adherence affects the sustained virologic response (SVR). Methods: We analyzed 92 chronic hepatitis C patients receiving peginterferon alpha and ribavirin combination therapy. Patients were first identified as having either genotype 1 or genotype non-1 infection and then categorized into three groups according to their adherence to the treatment protocol: (1) patients who received ≥80% of the recommended dosage of both peginterferon alpha and ribavirin for ≥80% of the intended duration of therapy, (2) patients who received <60% of the recommended dosage of both peginterferon alpha and ribavirin for <60% of the intended duration of therapy, and (3) patients who were not included in either group 1 or 2. Results: The rates of early virologic response, end of treatment response, and SVR differed significantly with the degree of adherence to the treatment. The SVRs of genotype 1 patients were 86.7%, 26.7%, and 66.7% in groups 1, 2, and 3, respectively (P=0.003), and those of genotype non-1 were 100%, 16.7%, and 88.9%, respectively (P<0.001). Conclusions: Adherence to therapy is a key factor in achieving an SVR. Supportive strategies to improve adherence will increase overall SVR rates. (Korean J Hepatol 2009;15:338-349)

사례보고 : 간절제술 후 원발병소인 간내 재발 없이 간외전이를 일으킨 간상피모양혈관내피종 1예

정승원 ( Soung Won Jeong ),우현영 ( Hyun Young Woo ),유찬란 ( Chan Ran You ),허원행 ( Won Hang Huh ),배시현 ( Si Hyun Bae ),최종영 ( Jong Young Choi ),윤승규 ( Seung Kew Yoon ),정찬권 ( Chan Kwon Jung ),정은선 ( Eun Sun Jung ) 대한간학회 2008 Clinical and Molecular Hepatology(대한간학회지) Vol.14 No.4

간상피모양혈관내피종은 혈관에서 기원하는 종양으로 간에서 발생하는 가장 드문 육종 중의 하나로서 저등도에서 중등도의 악성도를 가지고 있다. 아직까지 원인은 알려져 있지 않으며 예후 또한 예측하기 어렵다. 발생빈도가 낮고, 불균일한 특성, 다양한 임상경과 등으로 현재까지 정해져 있는 치료지침은 없다. 저자들은 64세 여자 환자에서 우엽에 발생한 간상피모양혈관내피종을 간절제술을 시행하고 22개월 후에, 원발병소인 간내 재발은 없이 골, 흉막, 복강 등으로 간외전이를 보인 사례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Epithelioid hemangioendothelioma is a neoplasm of vascular origin with a low-to-intermediate malignant potential and is one of the rare sarcomas arising from the liver. Its etiology is unknown and its clinical outcome is unpredictable. There is no generally accepted therapeutic strategy because of its rarity and the variable natural course between hemangioma and angiosarcoma. We report a case of a 64-year old woman who underwent hepatic resection due to epithelioid hemangioendothelioma in the right lobe that progressed to extrahepatic metastases of the bone, pleura, and peritoneum 22 months later. However, after resection there was no primary hepatic recurrence. (Korean J Hepatol 2008;14:525-531)

Somatic mutations of the <i>ERBB4</i> kinase domain in human cancers

Soung, Young Hwa,Lee, Jong Woo,Kim, Su Young,Wang, Young Pil,Jo, Keon Hyun,Moon, Seok Whan,Park, Won Sang,Nam, Suk Woo,Lee, Jung Young,Yoo, Nam Jin,Lee, Sug Hyung Wiley Subscription Services, Inc., A Wiley Company 2006 International journal of cancer: Journal internati Vol.118 No.6

<P><B>Abstract</B></P><P>The EGFR family consists of 4 receptor tyrosine kinases, EGFR (ERBB1), ERBB2 (HER2), ERBB3 (HER3) and ERBB4 (HER4). Recent reports revealed that the kinase domains of both <I>EGFR</I> (<I>ERBB1</I>) and <I>ERBB2</I> gene were somatically mutated in human cancers, raising the possibility that the other ERBB members possess somatic mutations in human cancers. Here, we performed mutational analysis of the <I>ERBB4</I> kinase domain by polymerase chain reaction–single‐strand conformation polymorphism assay in 595 cancer tissues from stomach, lung, colon and breast. We detected the <I>ERBB4</I> somatic mutations in 3 of 180 gastric carcinomas (1.7%), 3 of 104 colorectal carcinomas (2.9%), 5 of 217 nonsmall cell lung cancers (2.3%) and 1 of 94 breast carcinomas (1.1%). The 12 <I>ERBB4</I> mutations consisted of 1 in‐frame duplication mutation and 8 missense mutations in the exons, and 3 mutations in the introns. We simultaneously analyzed the somatic mutations of <I>EGFR</I>, <I>ERBB2, K‐RAS</I>, <I>PIK3CA</I> and <I>BRAF</I> genes in the 12 samples with the <I>ERBB4</I> mutations and found that 1 gastric carcinoma with <I>ERBB4</I> mutation also harbored <I>K‐RAS</I> gene mutation. Our study demonstrated that in addition to <I>EGFR</I> and <I>ERBB2</I>, somatic mutation of the kinase domain of <I>ERBB4</I> occurs in the common human cancers, and suggested that alterations of ERBB4‐mediated signaling pathway by <I>ERBB4</I> mutations may contribute to the development of human cancers. © 2005 Wiley‐Liss, Inc.</P>