체성분이 폐경 전후 여성의 골밀도에 미치는 여향

배성욱,남철현,신두만,차경미,서인선 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

Objectives : To evaluate the degree of bone mineral density and prevalence rate of osteoporosis according to age and to search the preventive strategy for osteoporosis, the factors that affect on bone density were studied in Physical Characteristics of pre- and postmenopausal women in korea. Methods : The subjects were 961 premenopausal and 1,167 postmenopausal women who have examined in health promotion center of Yeungnam University Hospital in Daegu city from January, 1999 to January, 2001. The test for bone mineral density, biochemical factors, and body composition were done. Results : 1) The prevalence rates of reduced bone mineral density and osteoporosis in premenopausal women were 23.8% and 1.6%, respectively. However, these values were increased to 46.1% and 28.1% in postmenopausal women. 2) The body weight and height were important predictive factors for bone mineral density. The effects of age, body weight, and height on bone mineral density were 39%. The body weight was correlated statistically significantly with bone mineral density in pre- and postmenopausal women. The higher body mass index (BMI), the greater value of bone mineral density was revealed in pre- and postmenopausal women. 3) The correlation between body composition adjusted for body weight and bone mineral density revealed similar pattern between pre- and postmenopausal women. The height, lean body mass, muscle mass, mineral content, and mineral fraction were positively correlated with bone mineral density, however, body fat mass, percent body fat, waist/hip ratio, and BMI were correlated negatively with bone mineral density. 4) There was no direct correlation between cardiovascular risk factor and bone mineral density in this study, however, further study is needed because cardiovascular disease and osteoporosis have common risk factor and the prevention of osteoporosis can help to prevent cardiovascular disease. 5) In multiple regression analysis among bone mineral density as a dependent variable and independent variables (age, body weight, height, Ca/creatinine ratio, and alkaline phosphatase (ALP)), ALP revealed statistically significant inverse correlation with bone mineral density. Conclusions : These results suggested that to prevent osteoporosis, the systemized program including physical condition for promoting anti-osteoporotic factor have to be developed and apply from the thirties whom have maximal bone mineral density.

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

지식관리시스템의 설계 및 구축

배재학,김영권,남철기,신필순 울산대학교 2000 공학연구논문집 Vol.31 No.1

기업의 지적자산을 직접적인 경영 대상으로 보는 새로운 인식이, 최근 지식경영이라는 이름으로 확산되고 있다. 이에 본 논문에서는, 실제 중소기업에서 지식관리와 재사용에 활용할 정보시스템의 설계 및 구축을 시도하였다. 구체적으로는, 지식관리 시스템 개발시 고려해야 할 사항, 개발방향 설정, 그리고 개발 방법론 등을 검토하였다. 이를 토대로 지식관리 시스템의 원형을 구현하였다. There is growing recognition by the name of knowlege management that tintellectual assets are the management objects that should be directly managed. In this paper, we try to design and implement an information system for knowledge management and reuse in small-to-medium-sized enterprises. In doing this, we study initial considerations, development directions ans methodology for knowledge management systems. Based on the study, a prototype of the knowledge management system is constructed and described here.

일부농촌 지역노인들의 유병상태와 일상생활 능력

신철호,이태용,이동배 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1

This study was conducted to investigate the prevalence rate, activity of daily living of rural elderly. The study group was composed of 820 old people aged 65 or more, living in Chungnam provincial area. The results obtained were as follows: 1. The prevalence rate rise rapidly with increasing age and that of male was 65.9%, and female was 70.8%. The prevalence rate of chronic diaseses were the highest in muscular disease and arthropathy as 51.5%, 16.8% in cerebrovascular disease and 12.6% in respiratory disease. 2. The ability score of daily living of male as 76.3% was similar that of female as 74.7%. The ability score of daily living went down with increasing age and statistically significant(P<0.01). The ability score of daily living of those who were not ill were higher than that of those who were ill. The ADL of those who have been a spouse was higher than that of those who were single. The number of family member and alcohol drinking influenced to the score of ADL, but level of education and smoking didn't influenced to that. The diseases that influenced to the score of ADL were cerebrovascular disease, cancer, and diabetes mellitus. The factors that influenced to the ADL were age, the presence of chronic disease, alcohol drinking, and the number of family members. 3. The score of cognitive function of male as 89.3% was higher than that of female as 86.1%. The score of cognitive function was the highest in 65-69 years of age. The presence of ill didn't influence the score of cognitive function. The score of cognitive function of those who have been a spouse was higher than that of those who were single. The number of family member, alcohol drinking, level of education, and smoking didn't influence the score of cognitive function. The score of cognitive function were high in renal disease, hepatic disease, and cancer, but that were low in cerebrovascular disease, muscular disease and arthropathy, and respiratory disease. The factors that influenced to the cognitive function were age, marital status.

푸드뱅크 기탁식품의 안전성 확보를 위한 HACCP 제도 적용

김철재,박현신,배현주,이지해,양일선,강혜승 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.3

The purpose of this study was to analyze the problems arising from the actual conditions of the Foodbank, and to implement the HACCP system as a solution in terms of increasing the safety of donated food within the Foodbank. In order to apply HACCP system, the entire Foodbank working process such as preparation, collection, transportation, division, and distribution was considered and analyzed to decide the application point for CCPs. Donated foods mainly consisted of processed foods, raw materials, lunch boxes, and cooked foods from mass catering establishments, which dominated over the others in terms of quantity. Cooked foods were divided into three groups based on menu-types and processing methods. Temperature, pH, and aw were measured on cooked foods, and Total Plate Count, Coliforms, E. coli, Salmonella spp., Staphylococcus aureus, Listeria monocytogenes, and E. coli O157:H7 were conducted in order to apply a HACCP plan. Form these experiments, temperature, pH, and aw of donated food were likely contributed to microbial growth. Donated foods before HACCP implementation showed high numbers in terms of total plate count and Coliforms, both well over the acceptable standard levels. By setting the CCPs on maintenance of donated food below 10℃ and using a 75 ℃ reheating method, microbiological hazard levels were able to be controlled and lowered. From these results, it is concluded that in order to guarantee food safety, foods donated to the Foodbank must not only maintain a reasonable level of initial microbiological growth, but also must be handled properly through time and temperature controls within the Foodbank system. Furthermore, in terms of implementing the HACCP plan within the Foodbank management structure, basic food safety and sanitation measures, such as reheating facilities and various cold chain systmes such as refrigerated vehicle for food transportation are importantly needed. The training and education of Foodbank personnel and management in areas such as awareness of hygiene and safe food handling and practice are also required and necessary.

에어로빅스 운동시 부상 유발 동작의 운동 역학적 분석

정철수,신인식,현무성,배성제,김복영,이기청 한국운동역학회 1995 한국운동역학회지 Vol.5 No.1

One of the reason that the aerobic dance is popular for korean women is that it is considered as a moderate aerobic exercise. However, high rate of aerobic dance related injuries have been reported among the participants. The purpose of this study was to estimate the impulsive load to the body while performing certain aerobic dance movement. Based on the preliminary questionairs on aerobic dance injury for 210 replyees, two aerobic dance movements including Run and High Kick were identified as high injury induced movements. The impulsive loads during aerobic dance estimated were joint angular acceleration and the vertical ground reaction force. The joint angular acceleration was determined using a 3-D cinematography technique, and the ground reaction force was measured with using an AMTI force platform system. It was founded that : the peak vertical ground reaction force 1738.7±171.2N, 1990.9±134.9N for Run, High Kick respectively. The peak vertical ground reaction force during High kick movement reached 3.7 body weight, which exceeded 3 body weight of force that can be experienced during jogging. These results indicates that although the aerobic dance movements look moderate means of exercise, certain movement ca produce highly impulsive look to the body and can aggravate injury when the movement is, kept repeated faster than the speed of healing process.

Cd²+ 投與에 의한 腎臟 Naf, Kf-ATPase의 抑制

李神雄,李正秀,裵基哲 嶺南大學校 環境問題硏究所 1989 環境硏究 Vol.9 No.1

Weekly intraperitoneal injections of 2mg per kilogram of cadmium acetate for 2 weeks induced persistent hypertension in rats. Body and kidney weights of cadmium hypertensive rats did not differ from those of control normotensive rats. Cadmium concentration in control and ??-treated rat kidney was 1.35㎍/g wet Wt, and 52.6㎍/g wet Wt, respectively. ??,??-ATPase activity of microsomal fractions or tissue homogenate of ?? treated rat kidney was significantly lower than of control. ?? and ouabain inhibited ??, ??-ATPase of control microsome in vitro with ?? value of about ?? and ?? , respectively. These results suggest that cadmium accumulated in kidney inhibits renal ??, ??-ATPase.

멀리뛰기 발구름 동작시 아킬레스건각이 도약속도와 도약각도에 미치는 영향

김복영,배성제,신인식,정철수,임규찬 師範大學 體育硏究所 1992 서울大學校 體育硏究所論集 Vol.13 No.2

The purpose of this study was to investigate the effect of lower leg planting angle an on take-off motion of the long jump. The Achilles tendon angle defined as the angle between shank and calcaneus with projection to XY plane was introduced to interprete lower leg motion uring last foot touch for the flight phase of long jump. A typical high speed film analysis technique including DLT method was adapted to record and analyze total of nineteen long jumps performed by elite athletes at two different track and field events. The following were found that: 1. The relationship between touch-down velocity, take-off velocity, range of vertical velocity and flight length were significantly related each others as r=0.6383, 0.6395 respectively at t=0.01 level. 2. It was not possible to reveal the relationship between take-off angle and flight length. Due to highly consistent take-off angles shown between the long jumpers. 3. The angular displacement of the shank during the last foot contact just before flight phase was negatively related to the flight length(r= -0.6149). However, it was not possible to find the relationship between the aehilles tendon angle and flight length. 4. As the range of the body C.O.G lean angle increased the last step foot contact time significantly increased(r=0.8625). 5. The foot contact time of Korean elite long jumpers was somewhat longer than that shown by foreign Athletes. It is concluded that maintaining touch-down velocity during initial phase of foot touch and increasing take-off velocity would result optimal take-off angle and good record. Decrease in the angular displacement of the shank, foot contact duration, and the range of body C.O.G lean angle were found to be important to improve the flight length.

Tourette 장애 소년에서 자기공명영상을 이용한 기저핵의 용적 분석

선우영경,신용범,이명지,김지영,배재남,강민희,김철응,이정섭 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.4

Objectives : The purpose of this study was to investigate the regional differences of the basal ganglia volume between the boy subjects who have Tourette's disorder and the control group who don't have this disorder by using Brain MRI. Methods : Sixteen subjects who were diagnosed as Tourette's disorder using DSM-IV criteria, and sixteen healthy subjects were selected. For analysis the coronal slice images of the basal ganglia were collected and collected MR images were analyzed with NIH Image (version 6.1 ppc). Resuls : The total brain volume in the subjects with Tourette's disorder were smaller than control group by 6.2% (F=6.2, d.f.=1, P=0.019). The right putamen volume in boys with Tourette's disorder were significant smaller than control group statistically (F=3.2, d.f.=3, P=0.040). The asymmetry (1eft>right) in the globus pallidus decreased significantly in the boys with Tourette's disorder (p=0.06) were found from this experiment. Conclusion : These findings suggest that boys with Tourette's disorder may have neuropathological abnormalities in the basal ganglia. Moreover, the present findings point out the important role of basal ganglia, especially putamen, in Patho-physiology of Tourette's disorder. More studies about the structural and functional analysis of the basal ganglia in Tourette's disorder are highly required.

하지 절단자 보행의 운동역학적 분석

임규찬,박윤서,배성제,정철수,신인식,김복영 師範大學 體育硏究所 1994 서울大學校 體育硏究所論集 Vol.15 No.2

This study was conducted to investigate the biomechanical characteristics of the gait pattern in an amputee for the purpose of improving the proper gait posture and designing the prosthetic. The subjects were six males amputees and one normal person. The ground reaction force was measured using AMTI force platform. The conclusions were as follows; 1. In case of amputee group, the ground reaction force was revealed in specific figure according to position in which they used the prosthetic, whereas in case of normal person the ground reaction force was revealed in the figure of two humps in regard of vertical axis. 2. In case of amputee group, the ground reaction force in time between fight foot contact and left foot contact was deviated from a figure of rectangle, whereas in case of normal person the ground reaction force was revealed in the figure of rectangle. 3. In case of amputee group, the ground reaction force referred to both feet angle point of view was revealed in irregular figure, whereas in case of normal person the ground reaction force was revealed about 47。