지중내 공동 탐지를 위한 비파괴 검사 기법에 대한 실험적 연구

유정동(Jund Dong?Yoo),양학모(Hak Mo?Yang),장기창(Ki Chang?Jang),강승민(Seung Min?Kang),조소현(So Hyun?Cho),김현기(Hyun-Ki?Kim),Seung Soo?Kim,Da Bin?Jin 대한토목학회 2018 대한토목학회 학술대회 Vol.2018 No.10

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

이면성 및 도플러 심초음파도를 이용하여 진단한 선천성 거대 좌회선지-좌심실 관동맥루

진승원,박준철,이영중,유병현,박현옥,김용주,윤호중,김재형,홍순조,최규보,권종범,원용순,박건 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

모래다짐말뚝의 원심모델링

유남재,정길수,김상진,채승호 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

This paper is results of extensive centrifuge model experiments about design factors influencing the bearing capacity and the settlement behaviors of SCP (Sand Compaction Pile). Centrifuge model tests were carried out changing design factors for SCP method such as replacement area ratio (as= 20, 40, 70%), improvement ratio to footing width (W/B = 1, 2, 3), and amount of fines in sand pile (#200 = 5, 10, 15). Therefore, the effects of these design factors on the bearing capacity and the settlement behavior of SCP were investigated and changes of stress concentratio rato due to such an design factors were also investigated. Centrifuge model testing technique for preparing and installing centrifuge model of sand compaction pile, using freezing them, was also developed. As results of centrifuge model tests, more fines in sand compaction pile increases the bearing capacity of SCP. Optimum improvement ratio to footing width was found to be 2. Values of stress concentration ratio was in the ranges of 1.5 - 3.5. The depth of bulging in sand piles was found in the range of 2.0 - 2.5 times of pile diameter.

비만 청소년의 심폐기능과 혈중지질에 관한 연구

유승희,김성진 慶熙大學校 1997 論文集 Vol.26 No.-

The purpose of this study was to investigate how exercise affect the cardiorespiratory function and level of serum lipids in adolescent obesity. The test subjects were twenty obesity men(obesity group) and twenty general men(general group) enrolled at N.S junior high school in March, 1997. The age of subjects were distributed between thirteen and fifteen. The heart rate(HR), VO_2max, systolic blood pressure, and serum lipids were measured before and after the Ergometer exercise for 12 minutes. All data were processed by IBM package SPSS-PC^+ for statistical analysis. The results obtained in this study were summarized as follows; 1. The %fat were 13.9±1.86% in general group and 24.5±1.68% in obesity group. 2. The Heart Rate at resting were 75.4±7.02beats/min in general group and 85.8±5.53beats/min in obesity group. And the HR after twelve minutes ergometer exercise were 163.2±4.52beats/min in general group, 175.5±5.13beats/min in obesity group. 3. The Systolic Blood Pressure at resting were 117.0±7.32mmHg in general group and 121.0±6.41mmHg in obesity group. And the Systolic Blood Pressure after twelve minutes ergometer exercise were 160.3±6.58mmHg in general group, 169.0±8.67mmHg in obesity group. 4. The VO_2max were 45.38±6.22㎖/㎏/min in obesity group. 5. The serum Total-Cholesterol level at resting were 133.3±16.01㎎/㎗ in general group and 179.9±30.82㎎/㎗ in obesity group. And the serum Total-Cholesterol level after twelve minutes ergometer exercise were 136.5±15.04㎎/㎗ in general group and 184.5±33.14㎎/㎗ in obesity group. 6. The serum Triglyceride level at resting were 61.8±11.77㎎/㎗ in general group and 112,3±22.55㎎/㎗ in obesity group. And the serum Triglyceride level after twelve minutes ergometer exercise were 69.7±12.08㎎/㎗ in general group and 120.9±20.09㎎/㎗ in obesity group. 7. The serum HDL-C level at resting were 48.4±4.97㎎/㎗ in general group and 36.9± 4.69㎎/㎗ in obesity group. And the serum HDL-C level after twelve minutes ergometer exercise were 49.2±4.49㎎/㎗ in general group and 38.9±5.79㎎/㎗ in obesity group. 8. The serum FFA level at resting were 565.1±125.09㎎/㎗ in general group and 679.2 ±179.76㎎/㎗ in obesity group. And the serum FFA level after twelve minutes ergometer exercise were 720.1±131.59㎎/㎗ in general group and 882.9±191.57㎎/㎗ in obesity group.

비소세포암에서 C-erbB-2와 COX-2 발현의 면역조직화학적 관련성

유승진 외 중앙대학교 의과대학 의과학연구소 2010 中央醫大誌 Vol.35 No.1/2

Background & Purpose: The study for inhibitors of gene products participating in multistep carcinogenetic event of human cancer is important target relevant to chemoprevention or adjuvant therapy of cancer. This study was performed to search basic data for chemoprevention or adjuvant therapy of human non-small cell lung cancer and to evaluate coexpression of each gene product, the relationship between the expression of each gene product and clinicopathologic factor or prognosis. Method: The following formalin-fixed paraffin embedded surgical specimen was immunohistochemically stained by avidin-biotin complex method for C-erbB-2 and COX-2; 55 cases of squamous cell carcinoma and 29 cases of adenocarcinoma of lung. Results: Positive C-erbB-2 and COX-2 expression is more often seen in adenocarcinoma compared with squamous cell carcinoma. Correlation between early and advanced cancer was insignificant. Coexpression of C-erbB-2 and COX-2 expression is more often seen in adenocarcinoma compared with squamous cell carcinoma. Conclusion: These results suggested that degree of C-erbB-2 and COX-2 expression depended upon histologic type of non-small cell lung cancer. However, further studies are required for the determination of significant relationship in coexpression of two gene products and clinicopathologic indices.

뇌졸중으로 인한 여성 편마비 환자와 일반인의 고관절 등속성 근력 비교분석

김홍진,유승희,이문규 경희대학교 체육대학 한국체육과학연구소 2002 體育學論文集 Vol.30 No.-

The purpose this study was to compare the difference of isokinetic muscle strength between general people and hemiplegia. Also, the experimental instruments used were Martin's anthropometer(PKS-100, Japan), weight meter(TBF-202, Japan), and isokinetic equipment(CYBEX NORM, USA). To analyze the data, the statistical method used in this study were mean, standard deviation, and t-test using SPSS for Windows(Version 10.0). Based on aforementioned research method, the results of this study are as follows. 1. Peak torque, pear torque % body weight. There is a marked difference on the left. On the case of the concentric contraction extension, there is also a marked difference on the right. 2. Angle of Peak torque. There is a marked difference in concentric contraction flexion 180°/sec of both sides and eccentric contraction flexion 60°/sec, extension 180°/sec of the left. 3. Total work, total work % body weight. There is a marked difference on the hip except concentric contraction flexion. 4. Average power, average power % body weight. There is a marked difference on the hip except concentric contraction flexion. 5. Peak torque in antagonists. There is a marked difference in concentric contraction left 120·180°/sec and eccentric contraction left 180°/sec.

Cellulose 생합성 세균의 분리 및 특성

이승진,유주순,정수열,최용락 東亞大學校附設遺傳工學硏究所 1998 遺傳工學硏究 Vol.- No.5

발효시켜서 만드는 감식초에서 시료를 채취하여 배양하고, pellicle을 형성하는 single colony를 cellulose생합성균으로 분리하였다. 분리된 균주는 형태적 특성, 알콜의 재산화 등의 생리, 생화학적 특성 등에 의하여 Acetobacter속으로 분류되었으며, Acetobacter CBI-2라고 명명하였다. Acetobacter CBI-2는 정지배양 시에 기존의 생합성 균주로 알려진 Acetobacter xylinum과 대등한 cellulose생합성 능력을 나타내었다. Acetobacter CBI-2이 생성한 고분자물질의 분해산물을 TLC법으로 확인한 결과 기존 cellulose의 것과 일치하였다. Acetobacter CBI-2에서 genomic DNA를 분리 정제하여 cel A 영역을 probe로 하여 hybridization시킨 결과, 상동성을 나타내어 분리 균주에는 cellulose 생합성 관련 유전자가 존재함을 나타내었다.(1997년 1월 7일 접수, 1997년 2월 24일 수리). A screening was performed to isolate the cellulose-producing microorganisms from vinegar in Korea. The isolated strain was identified as Acetobacter sp. with respect to physiological and biochemical characteristics and designated as Acetobacter CBI-2. Cellulose production of Acetobacter CBI-2 was equal with the well known cellulose-producing bacteria, A.xylinum. The result of separation on thin layer chromatography (TLC) was consistent with the degradation product of native cellulose. The presence of genes required for the cellulose biosynthesis in Acetobacter CBI-2 was confirmed by Southern hybrization.

소아에서의 급성 파종성 뇌척수염의 임상적 고찰

조수진,박은애,유은선,김혜순,손세정,서정완,이승주,한후재 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

목적: 급성 파종성 뇌척수염은 감염이나 예방 접종 후 발생하는 중추 신경계의 급성 자가 면역 염증성 질환으로 탈수초를 일으킨다. 신경학적인 증상으로 발현되고 대부분 환전히 회복되지만 신경학적 후유증을 남기거나 사망 할 수도 있다. 이에 저자들은 본원에서 발생 한 14명을 분석하여 조기 진단과 치료에 도움을 주고자 하였다. 대상과 방법: 1998년 3월부터 2003년 8월까지 이대목동병원에서 급성 파종성 뇌척수염으로 진단 받은 14명의 의무기록을 후향적으로 조사하였다. 결과: 환자들의 평균 발생 연령은 5±7.8개월이였고, 특정계절이나 연도에 집중되어서 나타나지는 않았다. 선행질환은 주로 비특이적인 상기도 감염이 가장 많았고, 초기증상으로는 경련이 가장 많았다. 그 외에 의식저하나 운동장애도 있었다. 뇌척수액 검사에서 백혈구 증가증이 발견된 경우는 있었으나 단백이 증가된 경우는 없었다. 뇌 자기공명 촬영에서 T2 증강시 뇌백질과 기저핵에 고음영의 다발성 병소가 발견되었고 추적 촬영에서 대부분에서 소실되었다. 뇌파 검사가 시행되었던 경우 전반적인 서파가 가장 많았고 국소적인 극파가 나온 경우도 한 명 있었다. 환자들은 정맥 면역 글로블린과 메틸프레드니졸론으로 치료하였고 치료 시작 후 3~7일내 증상이 호전되었다. 모든 환자를 2달 이상 추적 관찰하였고 항경련제가 지속적으로 필요한 정도의 경련성 질환이 두 명, 신경아교증이 남아잇는 경우가 한 명, 외래에서 다발성 경화증이 의심되는 경우가 한 명 있었다. 결론: 급성 파종성 뇌척수염은 침범 부위에 따라서 다양한 임상 상으로 나타나며 면역 글로블린과 메틸프레드니졸론이 치료에 효과적이였다. 본 연구에서는 대상 환자수가 적어 신경학적 후유증의 위험요소는 밝힐 수는 없으나, 예후는 검사소견과 연관되어 있지는 않았고, 대부분에서 양호하여 완전히 회복되었으나, 신경학적 후유증이 남은 경우도 있었다. Objective:Acute disseminated encephalomyelitis(ADEM) is an acute demyelinating autoimmune inflammatory disease of the central nervous system which develops after infection of vaccination. It may be fatal, and produce a permanent residual static disability or fully recover. We retrospec-tively studied 14 cases to investigate the clinical findings and outcome of ADEM. Methods : 14cases of ADEM diagnosed at Ewha Womans University Mokdong Hospital from 1998 to 2003 were retrospectively reviewed. Results : The age of onset was 5years±7.8 months and no seasonal clustering was found. The time of onset of symptoms was between 3 to 30 days. The preceding events were nonspecific upper respiratory infections in 9 cases, aseptic meningitis in 4 cases, and gastroenteritis in one case..The initial symptoms were seizure, altered consciousness, hemiparesis, fever, headache, and vomiting. Brain MRI showed multifocal high signal intensity lesions on T2 weighted image mainly in the cerebral whith matter, basal ganglia and periventricular white matter. EEG was performed in some cases and showed generalized or focal slow waves and only one case showed focal spikes. Patients were treated with IV globulin and methylprednisolone and the symptoms improved within 3-7 days after treatment. All patients were followed up for more than 2 months and most of them fully recovered except two. Conclusion : ADEM presents in various clinical manifestations depending on its involvement of the brain lesions. Most cases recovered fully but in some cases, residual permanent neurologic sequelae remained.

Cellulose 생합성균주 Acetobacter sp. CBⅡ의 분리 및 특성

이승진,유주순,최용락 동아대학교 환경문제연구소 2000 硏究報告 Vol.23 No.1

The strain of cellulose-producing CBⅡ was isolated from the traditionally fermented persimmon vinegar, and identified as Acetobacter sp. CBⅡ with respect to physiological and biochemical characteristics. The isolated strain was cultivated statically in broth culture, a thick cellulose pellicle was formed. It was found that the strain was fluorecenced with UV light when the strain was cultivated agar medium contained Tinopal. The strain produced acetic acid from ethanol, and then decomposed acetate to CO₂ and H₂O. Capacity of cellulose biosynthesis from isolated strain was compared with Acetobacter xylinum ATCC 53582. The cellulose produced by the isolated strain was purified and cegraded by HCl. The released sugar was separated on thin layer chromatograpy(TLC) consistent with the degradation product of native cellulose.