원행을묘정리의궤 중 조리면에서 본 죽상 . 미음상 및 현륭원에서의 상차림고

김상보,이성우,한복진 한국식생활문화학회 1989 韓國食生活文化學會誌 Vol.4 No.4

To analyze dialy meal of royal meal, studied Jook Soora Sang (Rice Gruel), Mieum Sang (Thin Gruel) and Bankwa Sang, Soora Sang in Hyun Neung Won were on record Wonheng Ulmyo Jungri Euigwae (1795). Historic book "Jungri Euigwae" described the king's visit to his father's royal tomb "Hyun Neung Won", during the domain of Cheung Jo, the 22nd king of Choson Dynasty. The results obtained from this study are as follows. Rice Gruel (Jook Soora Sang), taken before breakfast, was arranged the same as the Soora Sang. The table for thin gruel (Mieum) was arranged in three kinds of sets; one for thin gruel, the others for stewed meat (Goem) and sugared fruit (Jeong Kwa). The diet seems to have been quit scientific and restorative. Bankwa Sang and Soora Sang in Hyun Neung Won was arranged the same as the other Bankwa Sang and Soora Sang. Therefore setting the table of royal meal had a rule.

골다공증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이남수,이상건,이상범,이상우,이선정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : As the average lifespan of human increases, osteoporosis and osteoporosis-related fractures have become major health care problems. Despite recent advances in medical treatment, few studies have assessed the recognition of osteoporosis in general adults. This study examined the recognition of osteoporosis and analyzed the relating factors. Method : A population-based sample of 1086 adults in Asan-city, Korea was investigated with questionnaires and height, weight, Information regarding the general characteristics(gender, age, economic state), lifestylef exercise, smoking, alcohol),medical history(progestin, GH, steroid, calcitonin, PTH), demographic parameter, obesity, stress, and family history was collected through an interview using a structural questionnaire. The level of obesity was measured by the body mass index(BMI). BMD(Bone mineral density) at the lumbar spine and femoral neck was measured by dual energy X-ray absorptiometry. Osteoporosis was considered to be T-score below -2.5. Results : The prevalence of osteoporosis increased progressively with age, decreased with BMI and predominant in women by the result of x^(2) -test, T-test. Age, weight, BMI were significantly correlated with osteoporosis by the result of Pearson correlation ana1ysis(P<0.05). And age, gender, BMI, family history of osteoporosis were proved to be significant risk factors of osteoporosis by the result of multiple logistic regression(P<0.05). Conclusion : These results suggest that age, gender, BMI might be the most important risk factors of osteoporosis. And the history taking about family history of osteoporosis is helpful for diagnosing osteoporosis.

서울시 지하철 역사내부의 음향특성평가에 관한 연구

이상우,정대업,이수열,차상곤,심명석 대한건축학회 2003 대한건축학회논문집 Vol.19 No.4

This study aims at providing useful data for the design of underground stations through an extensive survey of acoustic properties in underground stations in Seoul. In order to improve the sound efficiency at the underground station, sound characteristics in the space of the underground station were studied. Architectural features of underground stations located in Seoul were examined by visiting every site and analyzing drawings. The distinction in architectural features of this study resulted in the line-side section, the shape of under-platform section and ceiling material. Number of underground stations was selected and categorized based on architectural features, such as line-side section, the shape of platform section and ceiling material. Each selected station was revisited and the noise levels were measured and compared with the architectural features. The study found that the Sum-Sik type is more efficient than the one of the Sang-Dae-Sik type, which can be used for subway stations. The semi-circular section for the railway-side seems to contribute on the attenuation of noise transmitting from trains to the platform. In addition, the aluminum absorbing panel, net luber and zinc plate (panel 40% and net 60%) as ceiling meterial are more efficient than the horizontal aluminum spendral panel, vertical aluminum spendral panel with line and zinc plate (panel 40% and net 60%), respectively.

韓國産 자작나무科의 系統分類學的 硏究(序論)

李相泰,蘇雄永,田寬培,李愚喆 全北大學校 生物學硏究所 1981 生物學硏究年報 Vol.2 No.-

The present paper is an introduction to the whole project of "The systematic studies on Korean Betulaceae". Three studies under the project were performed this year and presented in this report : a review of taxonomic literatures and the construction of distribution maps by Woo-Tchul Lee, pollen morphology by Sang-Tae Lee and Moo-Yeol Kim, and wood anatomy by Woong-Young Soh and Kwan-Bae Jeon.

하지 수술을 위한 경막외 마취시 Ropivacaine 과 Bupivacaine 의 비교

이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

Comparison of Epidural Ropivacaine and Bupivacaine in Patients Undergoing Lower Extremity Surgery Chul-Jun Mun, M.D., Sang-Gon Lee, M.D., Jong-Suk Ban, M.D. and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea Background: Ropivacaine is an amide local anesthetic structurally related to bupivacaine. A ran-domized, double-blind study was performed to compare the clinical effectiveness of ropivacaine and bupivacaine in patients undergoing lower-extremity surgery. Methods: Forty-nine patients (ASA Ⅰ-Ⅱ) were randomized to receive 15 ml of 0.5% ropivacaine or bupivacaine. Twenty patients received 15 ml of ropivacaine and 20 patients received 15 ml of bupiva-caine at the L3,4 or L4,5 interspace. Parameters measured were the onset time, duration and spread of sensory block, the onset time, duration and degree of motor block, the quality of anesthesia and the heart rate and blood pressure profile during the block onset. Results: Demographic characteristics were similar among the groups. Seven patients were excluded from the study due to technical failure of the block, two patients were excluded due to insufficient data. The onset and duration of analgesia at T10 dermatome (mean ?? SD) was 18.9 ?? 7.0 minutes and 187.5 ?? 34.6 minutes respectively for ropivacaine, and was 15.2 ?? 8.8 minutes and 187.8 ?? 40.0 minutes respectively for bupivacaine. Maximum block height (mean ?? SD) was T6.5 ?? 2.0 for ropivacaine and T6.4 ?? 2.0 for bupivacaine. The incidence of complete motor block (Bromage scale 3) was low in the ropivacaine group, being 3/20 for ropivacaine and 12.20 for bupivacaine. Conclusions: The sensory blockade profile of ropivacaine, administered epidurally, is similar to that obtained with an equal dose of bupivacaine. However motor blockade with ropivacaine is less intense, less frequent, and of shorter duration than with bupivacaine. (Korean J Anesthesiol 2001; 41: 434~438)

동종골수이식 후의 이식편대숙주 질환의 빈도와 임상양상 : 단일 병원 치료 경험 A Single Institution Experience

이규형,이제환,이정신,서철원,김상위,김성배,김정균,김신,김우건,김상희 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1

배경: 이식편대숙주 질환은 동종골수 이식후 발생할 수 있는 가장 중요한 합병증의 하나이다. 일반적으로 이식편대숙주 질환이 서구에 비하여 한국을 비롯한 아시아 국가에서 드물다고 알려져 있다. 방법: 저자들은 1993년 12월부터 1997년 6월까지 동종골수이식을 받은 전체 44명의 환자를 대상으로 급성 및 만성 이식편대숙주 질환의 빈도와 임상 양상을 조사하여 분석하였다. 대상환자중 남자가 27명 (61%) 이었고, 여자가 17명 (39%)이었다. 중앙연령은 33.5세 (범위, 16-47세)였다. 17명은 급성골수성 백혈병, 6명은 급성림프구성백혈병, 11명은 만성골수성백혈병, 8명은 중증재생불량성빈혈, 1명은 골수이형성증후군, 그리고 나머지 1명은 신경아세포종(neuroblastoma) 환자였다. 이식편대숙주 질환 예방으로 methodtrexate와 cyclosporine복합요법을 시행하였다. 결과: 3명에서 급성 이식편대숙주 질환이 이식후 18일에서 48일 사이에 관찰되었다(빈도, 7%). 급성 이식편대숙주 질환정도는 3도, 2도 그리고 1도가 각 한명씩이었다. 4도 급성 이식편대숙주 질환은 관찰되지 않았다. 13명의 환자가 만성 이식편대숙주 질환을 경험하였다(30%). 이들 중 10예는 제한성 병변이었고 3예는 전신성 병변이었다. 만성 이식편대숙주 질환의 주된 발병 증상 또는 징후는 황달/간기능 이상(8예)과 구강점막병변(4예)이었다. 한 명의 환자가 이식 후 107일에 간 이식편대숙주 질환에 의한 간부전으로 사망하였다. 결론: 한국인 환자에서는 동종골수이식 후 급성 및 만성 이식편대숙주 질환의 빈도가 구미의 환자에 비하여 상대적으로 낮고 그 정도도 덜한 것으로 보인다. 한국인 환자에 가장 적합한 이식편대숙주 질환 예방 방법의 정립을 위한 계속적인 연구가 필요하다고 사료된다. Background: Graft-versus-host (GVHD) disease is one of the most important complications after allogeneic bone marrow transplantation (BMT). Generally, it has been known that graft-versus-host disease is less frequent after allogeneic BMT in Asian countries including Korea when compared to western countries. Methods: We investigated the frequency and clinical pattern of acute and chronic GVHD in 44 consecutive patients who underwent allogeneic BMT between December 1993 and June 1997. There were 27 male (61%) and 17 female (39%) patients with median age of 33.5 years (range, 16-47). Seventeen patients had acute myelocytic leukemia (AML), 6 acute lymphocytic leukemia (ALL), 11 chronic myelocytic leukemia (CML), 8 severe aplastic anemia (SAA), 1 myelodysplastic syndrome, and 1 neuroblastoma. Methotrexate/cyclosporine combination was given for acute GVHD prophylaxis. Results: There patients (7%) developed acute GVHD median 31 days (range, 18-48) after BMT. There were one grade 3 acute GVHD involving the liver. There was no patient with grade 4 acute GVHD. Thirteen patients (30%) developed chronic GVHD median 100 day (range, 53-266) after BMT. Ten cases were limited stage and 3 were extensive stage. Frequent initial manifestations of chronic GVHD were jaundice/liver function abnormality in 8 cases and oral mucosal lesion in 4 cases. One patient died due to liver failure which were felt to be seconday to chronic GVHD 107 days after BMT. Conclusion: Acute and chronic GVHD are less frequent in Korean patients after allogeneic BMT when compared to historical data from patients from western Europe or United States. In cases of chronic GVHD, mild forms of disease predominate. Optimal strategy for GVHD prophylaxis in Korean patients remains to be defined.

Adult Patients with Congenital Muscular Torticollis Treated with Bipolar Release : Report of 31 Cases

Lee, Gun Sang,Lee, Myung Ki,Kim, Woo Jae,Kim, Ho Sang,Kim, Jeong Ho,Kim, Yun-Suk The Korean Neurosurgical Society 2017 Journal of Korean neurosurgical society Vol.60 No.1

Objective : We assessed the surgical results of bipolar release in 31 adult patients with uncorrected congenital muscular torticollis (CMT) and more than 12 months of follow-up. Methods : Thirty-one patients underwent a bipolar release of the sternocleidomastoid muscle (SCM) and were retrospectively analyzed. The mean follow-up period was 14.9 months (range, 12-30). The mean age at time of surgery was 30.3 years (range, 20-54). Patients were evaluated with a modified Lee's scoring system, cervicomandibular angle (CMA) measurement, and a global satisfaction rating scale using patient self-reporting. Results : The modified Lee's scoring system indicated excellent results in 4 (12.9%) patients, good in 18 (58.1%), and fair in 9 (29.0%) at the last follow-up after surgery. The improvements in neck movement and head tilt were statistically significant (p<0.05). The preoperative mean CMA was $15.4^{\circ}$ (range, 5.4-29.0), which was reduced to a mean of CMA of $6.3^{\circ}$ (range, 0-25) after surgery (p<0.05). The global satisfaction rating scale was 93.7% (range, 90-100). A transient sensory deficit on the ipsilateral lower ear lobe was noted in three cases. No significant permanent complications occurred. Conclusion : Bipolar release of the SCM is a safe and reliable technique for the treatment of CMT in adults.

인터페론 치료에 반응이 없었던 예들을 포함한 만성 B형 간염 환자에서 lamivudine의 단기 치료 효과

이상우,이엄석,김선문,서승원,양현웅,성재규,이승민,이병석,김남재,이헌영 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

The efficacy and safety of lamivudine administration according to the presence or abscence of past history of interferon treatment were studied in 22 patients with chronic active hepatitis B who were diagnosed at ChungNam National Univerity Hospital. Nine of these patiens were no responders to interferon treatment. The change of HBV DNA, serum ALT and HBeAg values was analyzed during 12 weeks of lamivudine treatment. The results were as follow : 1. The mean values of HBV DNA and serum ALT were significantly reduced from 1793 9 to 2.0 pg/ml and from 202.5 to 36.3 IU/L after lamivudine treatment (p<0.001). The mean reduction rates of serum HBV DNA and serum ALT were 99.7% and 70.4%. 2. HBV DNA was undetectable in 18 patierits(81.8%) and serum ALT was normalized in 16 patients(68.2%%) after 12 weeks of lamivudine treatment. But there were temporary elevations of serum ALT value comparing to pretreatment value in 5 patients. 3. HBeAg was undetectable in 4 patients(18.1%) and in these 4 patients, anti-HBe was detected after 12 weeks treatment. 4. There was no significant difference of HBV DNA clearance rate and normalization rate of serum ALT between above and below 200 pg/mI group according to pretreatment HBV DNA values(p=0.74, p=0.08). 5. Each clearance rates of HBV DNA in patients without previous interferon treatment and patients with previous interferon treatment were 84.6% and 77.8%(p=0.68). Each clearance rates of HBeAg in patients without previous interferon treatment and with previous interferon treatment were 15.5% and 22.2%(p=0.683). 6. During the treatment periods, adverse effects of lamivudine were negligible in most patients except temporary leukopenia in one patient. Conclusively, lamivudine treatment over the short term period for patients with chronic active hepatitis B was effective in suppression of viral replication and improvement of abnormal serum ALT. Also the efficacy of lamivudine treatment was out of all relation to previous interferon treatment and adverse effects of this drug were negliable. But further study for the efficacy of long term period-lamivudine treatment and appearance of mutant shoud be necessary.

비혈연간 동종 골수이식의 임상적 고찰 : 단일병원 임상 경험 A Single Institution Experience

이기현,이규형,이제환,이정신,박건욱,김상희,김우건 대한조혈모세포이식학회 1999 대한조혈모세포이식학회지 Vol.4 No.2

연구배경: 급만성 백혈병이나 재생불량성 빈혈을 포함한 혈액종양 질환 및 기타 악성 조양 질환에서의 동종 골수이식은 관해요법 후의 완치 및 재발방지와 장기 생존 효과를 가져와 최근 그 시행 빈도가 증가하고 있으며, 이에 따라 HLA가 일치하는 비혈연간의 동종골수이식 횟수도 늘어나고 있는 추세이다. 저자들은 본원에서 비혈연 동종 골수이식을 시행받은 13명의 환자들을 대상으로 그 성적을 분석하였고, 이것을 형제간 골수이식과 비교해 보고자 하였다. 방법: 1996년11월부터 1999년 6월까지 울산의대 서울중앙병원에서 타인 동종 골수이식을 시행받았던 환자 13명을 대상으로 골수이식 후의 생착정도와 합병증, 생존여부 등을 살펴보았으며, 이들의 성적을 1993년 12월부터 1999년 6월까지 본원에서 형제간 동종골수이식을 시행한 92명의 환자의 성적과 비교 분석하였다. 결과: 총 13명의 대상환자들의 중앙 연령치는 23세 (15-41세)이었고 이중 남자가 7명이었다. 일차관해 상태인 급성 골수성백혈병 환자가 2명이었고, 6명이 급성림프구성백혈병이었으며 이들 중 일차관해 상태는 3명 이차관해 상태인 환자는 2명이었다. 중증 재생불량성 빈혈이 1명이었고, 만성시기에 있는 만성 골수성 백혈병 환자가 1명이었고, blastic crisis에 있는 환자가 3명이었다. 주입된 골수의 단핵구수는 중앙값이 0.53×10^(8)/kg이었고, CD34+ 세포의 수는 1.2×10^(6)/kg 이었다. 모든 환자의 골수는 생착에 성공하였고 절대과립구가 500㎕ 이상을 보인 중앙 생착기는 18일(11-28일)이었다. 백혈구와 혈소판의 생착 시기는 형제간 골수이식과 비교하여 별다른 차이가 없었다. 적혈구와 혈소판의 수혈을 필요로 하였던 경우는 비혈연 동종 골수이식군에서 형제간 이식의 경우보다 의미있게 더 많았다. 급성 이식편대숙주반응의 빈도는 비혈연간에서 의미 있게 많았으며 (53.8% vs 10.9% p<0.001). , 급성 이식편대숙주반응이 나타나는 시기도 이른 경향을 보였다. (12일 vs 34일 , p=0.063). 만성 이식편대숙주반응과 간정맥폐쇄질환은 비혈연 동종 골수이식을 시행한 경우나 형제간 이식을 시행한 경우나 그 빈도에서는 유사함을 보여주었다. 13명의 환자중 6명이 생존하고 있었고, 이들의 중앙 추적기간은 275일(115-691일)이었다. 이들 13명의 2년 생존율은 42%였고, 전체생존기간(overall survival)은 130일이었다. 이것은 형제간 이식군에서 보인 전체 생존기간 529일과 의미있는 차이를 보였다,(p=0.0008) 결론: 비혈연간 동종 골수이식의 경우 형제간 골수이식에 비해 급성 이식편대숙주반응이 의미있게 심하였다. 비혈연 동종 골수이식의 전체 생존율은 형제간 이식에 낮음을 볼 수 있었으나 1년 이상 생존하고 있는 환자의 경우 장기적인 생존을 기대할 수 있겠다. Thirteen patients with various hematologic disorders underwent allogeneic bone marrow trnasplantation from HLA-matched unrelated donors (mud-BMT) at University of Ulsan, Asan Medical Center between November, 1996 and June, 1999. Their clinical characteristics and outcome after mud-BMT were compared to those of silbling donor allogeneic bone marrow transplantation (allo-BMT). The median age of thirteen patients who underwent mud-BMT were 23 years (range, 15-41) with seven male patients. Underlying disease were 2 patients with AML (all 1st CR), 6 with ALL(1st CR:3. 2nd CR:2 more advanced:1) 4 with CML(chonic phase:1, 1st blast crisis:3) and one with severe aplastic anemia. The median cell count of transplanted mononuclear cell and CD34+ stem cells were 0.53×10^(8)/kg and 1.2×10^(6)/kg, respectively. All patient engrafted with ANC over 500㎕ on median day 18 (range 11-28). The days of leukocyte and platelet engraftment were similar to those of ninety-two patients who underwent sibling donor allo-BMT. The amount of transfusion requirement in patients who underwent mud-BMT was significantly higher than that of patients who underwent sibling donor allo-BMT. The actuarial incidened of acute GVHD in mud-BMT was singificantly higher than that of sibling donor allo-BMT (53.8% vs 10.9% p<0.001). The median day of onset of acute GVHD was shorter in mud-BMT than sibling donor allo-BMT (day 12 vs day 34, P=0.063). Frequencies of VOD were similar between the two group (61.5% vs 52.2%). Among 13 patients who underwent mud-BMT, 6 patients were alive for median 275 days (range, 115-691 days). Overall median survival time is 130 days. Our study showed patients who underwent mud-BMT showed higher frequency of aGVHD. A fraction of patients are surviving longer than a year and likely to be long term survivors.

임상 검체에서 분리된 nontyphoid Salmonella에서의 integron의 빈도와 특징

이정은,박수진,김성한,김미나,이남용,이복권,이상오,김양수,우준희,최상호 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

Background : Nontyphoid Salmonella (NTS) is a leading cause of human food-borne enteritis, It has been known that integron, a naturally occurring gene capture and expression element, Plays an important role in the development and dissemination of multidrug-resistance. In this study, we investigated the prevalences and molecular characteristics of integrons in NTS clinical strains. Materials and Methods : Between 1995-96 and 2000-03, a total 261 NTS clinical strains comprising 39 serotypes were collected from clinical specimens. All strains were serotyped, and the MICs of ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, tetracycline, and trimethoprim were determined by agar dilution method. Integrons were detected by PCR amplification of integrase genes, and gene cassettes were determined by PCR and sequencing, Conjugation experiments were performed using E. coli J53 as a recipient. The clonal relationship was analyzed by pulsed-field gel electrophoresls (PFGE). Results : Of the 261 strains tested, class 1 integrons were present in 21 strains (8.0%). Class 2 and class 3 integrons were not found. The integron-positive rate was higher in S. Typhimurium (24.2% [8/33]) than in S. Enteritidis (2.0% [3/153]). Overall rates of antimicrobial resistance were higher in integron-positive strains. dhfr12-orfF-aadA2gene cassette was detected in 5 strains, aadA2in 4 strains, dhfr17-orfF-aadA5 in 2 strains, and addA1 in 1 strain. Ten integron-positive transconjugants were successfully selected. Among 8 integron-positive strains of S. Typhimurium, 7 had similar PFGE patterns. Conclusion: This study suggests that integrons are already playing a significant role in antimicrobial resistance in NTS. Continuous monitoring is needed to detect the emergence and spread of integron-mediated antimicrobial resistance.