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- 저자 : ( Sang Lin Kim ) (검색결과 442 건)
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Park, Jinbong,Jeon, Yong-Deok,Kim, Hye-Lin,Lim, Hara,Jung, Yunu,Youn, Dong-Hyun,Jeong, Mi-Young,Kim, Hyun-Ju,Kim, Sung-Hoon,Kim, Su-Jin,Hong, Seung-Heon,Um, Jae-Young Hindawi Publishing Corporation 2013 Evidence-based Complementary and Alternative Medic Vol.2013 No.-
<P>Obesity has become a major health threat in developed countries. However, current medications for obesity are limited because of their adverse effects. Interest in natural products for the treatment of obesity is thus rapidly growing. Korean Medicine (KM) is characterized by the wide use of herbal formulas. However, the combination rule of herbal formulas in KM lacks experimental evidence. According to <I>Shennong's Classic of Materia Medica</I>, the earliest book of herbal medicine, <I>Veratrum nigrum</I> (VN) has antagonistic features against <I>Panax ginseng</I> (PG), and the PG-VN pair is strictly forbidden. In this study, we have shown the effects of PG, VN, and their combination on obesity in high-fat (HF) diet-induced obese mice and in 3T3-L1 cells. PG, VN, and PG-VN combination significantly reduced weight gain and the fat pad weight in HF diet-induced obese mice. They also significantly decreased lipid accumulation and the expressions of two major adipogenesis factors, PPAR<I><I>γ</I></I> and C/EBP<I><I>α</I></I>, in 3T3-L1 cells. In addition, the PG-VN combination had synergistic effects compared with the mixture of extracts of PG and VN on inhibition of PPAR<I><I>γ</I></I> and C/EBP<I><I>α</I></I> expressions at lower doses. These results indicate a new potential anti-obese pharmacotherapy and also provide scientific evidence supporting the usage of herbal combinations instead of mixtures in KM.</P>
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요양병원과 병원에 입원한 노인의 기능상태수준의 차이에 관한 연구
김정인,이지전,이상욱,박웅섭,송재석 關東大學校 醫科大學 醫科學硏究所 2003 關東醫大學術誌 Vol.7 No.2
In Korea, the proportion of 65-year-old elderly population were gradually increased and over 7 percentage in 2000. To care elderly properly, various type of healthcare institutions is needed. There is general hospital and long-term care hospital among medical institution. In this study, difference of functional status and severity between elderly inpatients in general hospital and those in long-term care hospital was investigated. Comprehensive functional status of 577 patients that were hospitalized in 3 long-term care hospitals and 2 general hospitals was examined. On the contrary to our expectation, patients in long-term care hospital had lower activities of daily livings and more severe medical conditions than those in hospital. These results suggested that healthcare system and healthcare resource distribution for elderly patients are not worked efficiently.
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韓國人에서 HumFIBRA/FGA와 D21S11 遺傳座의 對立遺傳子 頻度와 遺傳的 變異의 分析
김윤신,황적준,이혜린,구태완,한길로,김성민,이혜승 大韓法醫學會 1998 대한법의학회지 Vol.22 No.1
Allele-and genotype frequencies of the two short tandem repeat (STR) loci, HumFGA and D21S11, were determined in Korean population(n=196). DNA typing was accomplished by applying fluorescence-labeled PCR products and a differently labeled sequenced allelic ladders, followed by automated analysis using ABI 377 automatic sequencer and GeneScan 2.02 software. Prior to typing, allelic ladder of each locus was constructed with a combination of all alleles occuring from the population sample. A total of 15 alleles and 48 genotypes with the heterozygosity of 0.854 for HumFGA, and 12 alleles and 33 genotypes with the heterozygosity of 0.787 for D21S11 are observed in a population of 196 genetically unrelated individuals. No deviations from Hardy-Weinberg equilibrium were observed(p=0.753 for HumFGA, p=0.262 for D21S11). The data presented here (power of discrimination and average power of exclusion) show that both STR Loci, HumFGA and D21S11, are very informative for individualization from criminal evidences, and are also useful for parentage testing.
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임용호,김상홍 啓明大學校 生活科學硏究所 1998 科學論集 Vol.24 No.-
The purpose of this study was to examine the concept, the idea, the development of theoretical research of 'sports for all' and the problems in its practice. The major findings obtained from this study were following: First, it was found that research products in the field of sports for all were in an infant stage and the concept was used confusedly and, that problems with the scope, nature, viewpoint of sports for all were appeared. Second, It was summaried that it was emphosized as the proliferation and integration of educational function through the all of the social-life and the lifelong time, and as the public policy of preparation of the sports for all in the literatural review the theory of sports for all,. Third, it was lack of the disciplinary and scientific research methods. Based upon these findings, it was suggested that it should be taken sports for all as a social phenomena, and the scientific method should be applied more for the better understanding of human leisure and sport behavior.
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大學敎育計劃과 經營의 效果的 方案 : 慶北大學校 敎養敎育을 中心으로 Problems and Suggestions
李相魯,陳渭敎,金慶麟 慶北大學校 師範大學 1982 敎育硏究誌 Vol.24 No.-
This study examined major objectives, the scope and content of curricular, instructional and evaluational procedures for general education, and some issues related with guidance services for college freshmen. Three hundred students and one hundred and thirty-seven professors in K.N.U. were sampled and their responses to current issues on general education were analyzed by means of interviews, questionnaire, and need assessment techniques. Syllabuses, courses of studies, and college bulletins of major universities in Korea were also reviewed. The major findings and suggestions of the present study were as follows: (1) It is necessary to maintain the division of general education which plans and administers curricular activities and academic affairs for college freshmen. But it seems advisable for each college to take primary responsibility for student guidance and student affairs for the college to which the freshmen belong. The division of general education should have cooperative and functional relationships with each college. (2) The organization of staff in the division of general education consists of a dean, an associate dean, a sectional chief of academic affairs, and eight assistants to the sectional chief (one per college or academic field). (3) The major objectives of general education identified are citizenship education emphasizing acquisition of general and profound knowledge and personality development, professional education of prerequisite learning for advanced and major study, and nationality education concerned with value clarification and development of morality and sociability. (4) In order to realize effectively the above objectives, college students should be required to take more than 42 credit hours in the area of general education curricular: 20-24 credit hours for prerequisite courses (national ethics, Korean history, philosophy, Korean, English, second foreign language, physical education, and military training); 12 credit hours for major-related optional courses; 6-10 credit hours for optional courses. (5) A provisional model of teaching for general education should include a systematic arrangement of the specification of instructional objectives, diagnosis of the entry behavior and remedial teaching, active participation on the part of students in instructional procedures, and the formative and summative evaluation. (6) Size or structure of classroom and class size for general education should be flexible and adjustable to the nature and instructional obectives of each subject-matter. Educational media and references for general education should be developed and provided, and special plan for system development and educational environment should be also considered for the enhancement of general education.
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이성현,장숙진,최상준,김영숙,한호림,문대수,박영진 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1
Background and Objectives : Microbial invasion of the amniotic cavity is a significant clinical problem in obstetrics leading to infectious morbidity of both the mother and the newborn. So rapid and reliable test to detect bacteria in amniotic fluid is urgently needed. The purpose of this investigation was to determine the feasibility of using the 16S rDNA PCR to detect bacteria in amniotic fluid. Material and Method : Amniotic fluid samples from 15 pregnant women with hydramnios, preterm labor, or old age pregnancy were analysed with universal bacterial PCR. We used universal primers which amplify a DNA fragment of 16s rDNA from all known bacteria and sequenced the positive samples to identify the bacterial species, In some cases, routine bacterial culture, WBC, and CRP were studied also. Result : Three of 15 pregnant women were positive in the PCR. DNA sequencing of the PCR product detected Staphylococcus epidermidis in one case, and Streptococcus anginosus in two cases. Conclusion : The broad-spectrum bacterial 16S rDNA PCR assay, in properly controlled conditions, may provide a fast and reliable means for the detection of bacteria in amniotic fluid. 배경 및 목적 : 양수강의 미생물 침습은 산모와 신생아 양자에게 감염성 질환을 야기할 수 있어 산과학에 있어 중요한 임상적 문제이다. 따라서 양수에서 세균을 검출할 수 있는 신속하고 믿을 만한 검사가 절실히 필요하다. 이 연구의 목적은 16S rDNA PCR을 이용하여 양수에서 세균을 검출할 수 있는지 그 실행가능성을 검사하는데 있다. 대상 및 방법 : 양수과다증이나 조기 분만, 노산 등이 있는 임산부 15인의 양수 검체를 16S rDNA PCR로 분석하였다. 모든 알려진 세균의 16S rDNA 분절을 중폭할 수 있는 보편적인 시동물질을 사용하여 증폭하였고, 양성 검체를 염기순서분석하여 세균 균종을 동정하였다. 일부 환자들에서는 세균 배양검사와 WBC, CRP 검사도 함께 시행하였다. 결과 : 15명중 3명의 임산부가 PCR에 양성이었고 PCR 산물을 DNA 염기순서분석한 결과 한 환자에서 Staphylococcus edidermidis가 다른 두 환자에서 Streptococcus anginosus가 검출되었다. 결론 : 광범위 세균 16S rDNA PCR 분석은 적절히 관리된 조건 하에서 양수내 세균 검출을 위한 신속하고 믿을 만한 방법을 제공해 줄 수도 있다고 생각되었다.
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임한혁,최득린,고은석,이혜경,임철완,이상진,홍현숙,최교창,김영화,박재성 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2
Purpose : To evaluate the utility of mammography and ultrasonography in study of morphologic differential diagnosis between malignant and benign mass. Materials and Methods : Average age of patients with breast cancer was 48.4 year-old, and that of fibroadenoma was 29.4 year-old. The equipments used for examination were MF-159 high frequency mammography(Bennet Co.) and Acoustic image 5200S. We evaluated mammographic findings about breast parenchymal pattern, calcification, margin and size of the mass associated tumor nature, and ultrasonographic findings about shape, height and width, internal homogenicity and echo pattern, wall contour, boundary echo, and posterior shadow in breast mass. Thirty-seven of mammographic findings and 34 cases of ultrasonogreaphic findings in pathologically proven breast cancer and 34 case of mammographic findings and 71 cases of ultrasonographic findings in breast fibroadenoma were reviewed retrospectively. Results : In mammographic study, the parenchymal patterns of breast cancer according to Wolfe classification were NI(16.2%), PI(24.3%), P@(37.8%), and DY(21.6%) and those in fibroadenoma were NI(3.1%), Pl(11.7%), P2(35.2%),and DY(50%). Mammographic findings about presence of calcification were as follows; only calcification(16.2%), only mass(51.3%), and mass with calcification(32.5%) in breast cancer, and only mass(91.2%), mass with calcification(8.8%) in fibroadenoma. The features of mass margins were classified as ill-defined margin(45.9%), well-defined(5.4%), and well-defined with partial spiculation(48.6%) in breast cancer and ill-defined(20.5%), well-defined(73.5%), and well-defined with partial spiculation(5.8%) in fibroadenoma. The mass were grouped by size; 1-2cm(37.8%), 2-4cm(45.9%), and 4-6cm(16.3%) in breast cancer and 1-2cm(79.4%), 2-4cm(17.6%), and 4-6cm (3.0%) in fibroadenoma. On ultrasonographic study, the shape of masses in breast cancer were lobulated(82.3%),oval(14.7%), and round(3.0%),and those in fibroadenoma were lobulated(14.0%), oval(57.7%), and round(18.3%). The cases that the height was longer than width were 32.3% in breast cancer and 0% in fibroadenoma. The findings about homogenecity and echo patterns were as follows; hypoechoic(52.9%) and mixed(47.1%) in breast cancer and hypoechoic(2.8%), hypoechoic(63.4%), and mixed(33.8%) in fibroadenoma. The margin of masses were smooth in 85.9% of fibroadenoma, and irregular in 73.6% of breast cancer. The boundary echoes of masses and decreased posterior echo shadow were seen only in 61.8% and 55.9% of breast cancer, respectively. Conclusion: The margin and calcifications are more clearly delineated on mammography but breast cancer and fibroadenoma, both are more commonly developed in dense parenchymal pattern(P2+DY),and there findings are easily obscured in mammography. So ultrasoography is very useful in these masses evaluation, especially amoung young patients.
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강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2
Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.
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