http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Ki Seol Yang ) (검색결과 85 건)
- 무료
- 기관 내 무료
- 유료
-
부검으로 확진된 알쯔하이머병 1예 : An Autopsy Report
한설희,이건국,양기화,장순환 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.1
While the clinical diagnostic accuracy of probable Alzheimer′s disease (AD) is 87-96% with a diagnostic sensitivity/specificity of 0 81-0 87, the unequivocal diagnosis of AD rests on histopathological evidence at brain autopsy and/or biopsy We report here a 92-year-old woman whose clinical presentation suggested a far advanced Alzheimer′s disease Formal neuropsychological evaluations were not applicable due to severe cognitive impairments With a relatively good general physical condition she could walk with aid during her last days no focal neurological signs were noted on a detailed examination Brain MRI revealed a diffuse cortical atrophy with a marked reduction in the hippocampal volume The brain obtained weighted 780g The cerebral hemispheres examined after fixation disclosed moderately severe atrophy in prefrontal and temporal lobes on coronal section, the hippocampus was likewise severely atrophied the lateral ventricles were moderately dilated On microscope examination, there were numerous senile plaques and neurofibrillary tangles in the neocortices. hippocampus and amyglada, compatible with advanced Alzheimer′s disease In summary we report the first Korean autopsy-proven case with advanced Alzheimer′s disease.
-
제2형 당뇨병 남성 환자에서 유리 테스토스테론과 성호르몬 결합 글로블린 농도
남기덕,김영설,박철영,오승준,김덕윤,우정택,김성운,양인명,김진우,최영길 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.24 No.6
연구배경:인슐린저항성은 제2형 당뇨병과 심혈관질환의 주요한 위험 인자로 성호르몬과 상호 관계가 있다고 알려져 있다. 그러나 여성과는 달리 남성에서는 연령과 인슐린저항성에 따른 유리 테스토스테론과 성호르몬 결합 글로블린 농도의 변화에 대한 연구가 부족한 실정이다. 그러므로, 본 저자등은 제2형 당뇨병 남성 환자에서 정산인과 비교해서 유리 테스토스테론과 성호르몬 결합 글로블린 농도를 측정하고 연령에 따른 변화 정도를 알아보고자 하였다. 방법:대상 환자 모두에서 연령과 체질량지수, 총 콜레스테롤, 중성지방, 공복혈당과 인슐린 농도를 측정하였다. 혈중 유리 테스토스테론 농도는 방사면역측정법(radioimmunoassay)을 이용해서 측정하였고, 혈중 성호르몬 결합글로불린은 면역방사계측측정법(immunoradiometric assay)을 이용해서 측정하였다(Diagnostic System Laoratories, Wbster, TX, USA). 결과:1)제2형 당뇨병 남성 환자에서 정상 대조군 남성에 비해 성호르몬 결합글로불린은 104.1±35.0 vs 25.7±3.5 mole×10??로 의미 있게 높았으나(p<0.001), 유리 테스토스테론은 13.7±9.5 vs 13.6±6.5 ng/dL로 차이가 없었다. 2)연령과 성호르몬 결합 글로블린 사이의 상관 계수는 제2형 당뇨병 남성 환자에서 0.40로 중등고의 양의 상관 관계를 보였고(p<0.001), 정상 대조군 남성에서 0.11로 유의한 상관 관계를 보이지 않았다. 연령과 유리 테스토스테론 사이의 상관 계수는 제2형 당뇨병 남성 환자에서 0.08, 정상 대조군 남성에서-0.17로 모두에서 유의한 상관 관계를 보이지 않았다. 3)연령과 체질량지수를 보정한 후에 제2형 당뇨병 남성 환자와 정상 대조군 남성에서 혈중 인슐린 농도, 유리 테스토스테론과 성호르몬 결합 글로블린 사이에는 상관 관계가 없었다. 결론:제2형 당뇨병 남성 환자에서 정상 남성에 비해 성호르몬 결합 글로블린 농도가 증가되어 있었으며, 유리 테스토스테론은 차이가 없었다. 연령이 증가함에 따라 성호르몬 결합 글로블린이 제2형 당뇨병 남성 환자에서 정상 남성에 비해 증가 폭이 의미있게 컸으며, 유리 테스토스테론은 변화가 없었다. Background: Insulin resistance is a risk factor for cardiovascular disease and type 2 diabetes mellitus. There are many previous studies indicating that insulin lowers serum sex hormone-binding globulin levels, and there is inverse correlation between insulin resistance and serum sex hormone-binding globulin levels in women. However, in men, a limited number of studies are available to explain the effect of sex hormone on age and insulin. Therefore, the present study was undertaken to investigate the relationship among free testosterone, hormone-binding globulin and age in type 2 diabetic men and control subjects. Method: Age, body mass index, total cholesterol, triglyceride, fasting blood sugar, and insulin concentrations were examined on 89 type 2 diabetic men and 47 control subjects. The free testosterone level was measured by commercially available double-antibody system (Radioimmunoassay). The sex hormone-binding globulin level was also measured by commercially available double-antibody system(Immunoradiometric assay). Results: 1) Sex hormone-binding globulin level was significantly increased in patients with type 2 diabetes. However, there was no significantly difference in free testosterone level between the two groups. 2) Sex hormone-binding globulin was positively correlated with age (r=0.4, p <0.001) in patients with type 2 diabetes. Sex hormone-binding globulin and free testosterone were not correlated with age in control sujects. 3) Free testosterone and sex hormone-binding globulin concentrations were not significantly related to serum insulin concentration after adjusting for age and body mass index. Conclusions: We observed increased sex hormone-binding globulin concentration in diabetes man, and was a positively related to age. Further studies are needed to understand the relationships between age, insulin resistance, testosterone, and sex hormone-binding globulin concentrations(J Kor Diabetes Asso 24:699~707,2000).
-
Preterm labor and cervical colonization with Mycoplasma, Ureaplasma and Chlamydia trachomatis
( Ki Yeol Yang ),( Eun Young Jung ),( Seo Yun Tong ),( Hyun Joo Seol ),( Bo Yon Lee ),( Eui Jung ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-
To evaluate the association of preterm labor and cervical colonization with Mycoplasma, Ureaplasma and Chlamydia trachomatis to know whether their infection are related to the outcome of preterm labor. We studied 83 singleton pregnancy between 24 and 36 weeks of gestation with preterm labor who delivered Kyunghee university medical center. The patients were divided into 2 groups. One group (n=36) presented preterm labor and the other group (n=47) presented preterm labor and preterm premature rupture of membrane. We evaluated whether detection of Mycoplasma, Ureaplasma and C. trachomatis affect gestational age at preterm labor and delivery, cervical length, Bishop score, CRP, WBC, pain regularity at admission day, pregnancy prolongation and preterm history in each group. Cervical swab was obtained for detection of Ureaplasma, Mycoplasma and Chlamydia trachomatis, using selective culture media. Pregnancy outcomes were reviewed and the test results were compared. Ureaplasma, Mycoplasma and C. trachomatis were detected in 13%, 59% and 6% respectively from 83 patients. In Preterm labor group, birth weight was lower when positive result of Mycoplasma, Ureaplsama and C.trachomatis was founded, respectively. Mycoplasma positive group and C.trachomatis positive group had shorter pregnancy prolongation and lower CRP at the time of admission. In preterm labor and PPROM group, Mycoplasma positive result showed higher 5 minute apgar score and C. trachomatis positive result revealed higher gestational age at preterm labor and lower CRP level. In the present study, we were not able to determine association of preterm labor outcome and detection of Mycoplasma, Ureaplsma and C.trachomatis.
-
-
-
양현석(Yang, Hyeon-Seok),설용수(Seol, Yong-Soo),김동주(Kim Dong-Joo),김한우(Kim Han-Woo),박정기(Park Jung-Ki) 한국IT서비스학회 2011 한국IT서비스학회 학술대회 논문집 Vol.2011 No.9
본 논문에서는 실버로봇을 위한 지능형 대화시스템을 제시한다. 논문에서 제시하는 대화시스템은 사용자 발화와 이전 대화, 도메인 정보를 사용하여 사용자의 의도 및 대화 문맥을 파악한다. 또한 사용자의 한국어 발화를 분석하여 화행을 파악하고 문장 내의 정보를 추출한다. 오류 발화를 고려한 문장 이해와 추출된 정보를 활용하여 더 적절하고 정확한 발화를 유도함으로써 보다 지능적인 서비스를 제공한다. 인식할 수 있는 발화와 생성할 수있는 발화들을 살펴보고 감정과 관련된 문장을 고려하여 구현된 대화시스템의 성능을 실험을 통하여 확인하였다.
-
Koo, Ki-Tae,Park, Jang-Yeol,Park, Jun-Seok,Kim, Tae-Il,Seol, Yang-Jo,Lee, Yong-Moo,Ku, Young,Rhyu, In-Chul,Chung, Chong-Pyoung Korean Academy of Periodontology 2009 Journal of Periodontal & Implant Science Vol.39 No.2
Purpose: The objective of this clinical presentation was to present a clinical case series report of socket preservation, sinus augmentation, and bone grafting using a horse-derived biomaterial. Methods: A horse-derived biomaterial was used in 8 patients for different indications including socket preservation following tooth extraction, osseous bone grafting, and sinus augementation procedures. Surgeries were performed by a well trained specialist and clinical radiographs were obtained at designated intervals. Biopsy cores of 2 ${\times}$ 8 mm prior to implant placement was obtained following a healing interval of 4 - 6 months. A clinical and histologic evaluation was performed to evaluate the clinical effectiveness and biocompatibility of the biomaterial. Results: All surgeries in 8 patients were successful with uneventful healing except for one case with membrane exposure that eventually resulted with a positive outcome. Radiographic display of the healing phase during different intervals showed increased radiopacity of granular nature as the healing time increased. No signs of adverse effect or infection was observed clinically and the tissues surrounding the biomaterial seemed well-tolerated with good intentional healing. The augmented sinuses healed uneventfully suggesting in part, good biocompatibility of the biomaterial. Dental implants placed following socket preservation were inserted with high initial torque suggesting good initial stability and bone quality. Conclusions: Our results show that at least on a tentative level, a horse-derived biomaterial may be used clinically in socket preservation, sinus augmentation, bone grafting techniques with good intentional healing and positive results.
-
-
Kim, Ki Chan,Cho, Kyu Suk,Yang, Sung Min,Gonzales, Edson Luck,Valencia, Schley,Eun, Pyeong Hwa,Choi, Chang Soon,Mabunga, Darine Froy,Kim, Ji-Woon,Noh, Judy Kyoungju,Kim, Hee Jin,Jeon, Se Jin,Han, Seol The Korean Society of Applied Pharmacology 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.4
Autism spectrum disorder (ASD) remains unexplained and untreated despite the high attention of research in recent years. Aside from its various characteristics is the baffling male preponderance over the female population. Using a validated animal model of ASD which is the telomerase reverse transcriptase overexpressing mice (TERT-tg), we conducted ASD-related behavioral assessments and protein expression experiments to mark the difference between male and females of this animal model. After statistically analyzing the results, we found significant effects of TERT overexpression in sociability, social novelty preference, anxiety, nest building, and electroseizure threshold in the males but not their female littermates. Along these differences are the male-specific increased expressions of postsynaptic proteins which are the NMDA and AMPA receptors in the prefrontal cortex. The vGluT1 presynaptic proteins, but not GAD, were upregulated in both sexes of TERT-tg mice, although it is more significantly pronounced in the male group. Here, we confirmed that the behavioral effect of TERT overexpression in mice was male-specific, suggesting that the aberration of this gene and its downstream pathways preferentially affect the functional development of the male brain, consistent with the male preponderance in ASD.
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
