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      • KCI등재

        Effects of Edta on the Electronic Properties of Passive Film Formed on Fe-20Cr In pH 8.5 Buffer Solution

        Cho, EunAe,Kwon, HyukSang,Bernard, Frederic 한국부식방식학회 2003 Corrosion Science and Technology Vol.2 No.4

        The electronic properties of the passive film formed on Fe-20Cr ferritic stainless steel in pH 8.5 buffer solution containing 0.05 M EDTA (ethylene diammine tetraacetic acid) were examined by the photocurrent measurements and Mott-Schottky analysis for the film. XPS depth profile for the film demonstrated that Cr content in the outermost layer of the passive film was higher in the solution with EDTA than that in the solution without EDTA, due to selective dissolution of Fe by EDTA. In the solution with EDTA, the passive film showed characteristics of an amorphous or highly disordered n-type semiconductor. The band gap energies of the passive film are estimated to be ∼ 3.0 eV, irrespective of film formation potential from 0 to 700 mV_(SCE) and of presence of EDTA. However, the donor density of the passive film formed in the solution with EDTA is much higher than that formed in the solution without EDTA, due to an increase in oxygen vacancy resulted ti-om the dissolution of Fe-oxide in the outermost layer of the passive film. These results support the proposed model that the passive film formed on Fe-20Cr in pH 8.5 buffer solution mainly consists of Cr-substituted γ-Fe₂0₃.

      • Ab initio study on the carbon nanotube with various degrees of functionalization

        Cho, Eunae,Kim, Hanchul,Kim, Changwook,Han, Seungwu Elsevier 2006 Chemical physics letters Vol.419 No.1

        <P><B>Abstract</B></P><P>We present our ab initio results on carbon nanotubes functionalized with dichlorocarbene (CCl<SUB>2</SUB>). We find that the electronic properties of carbon nanotubes are significantly modified depending on the site of [2+1] cycloaddition. The random addition of dichlorocarbene is found to reduce the band gap of semiconducting nanotubes while those of metallic nanotubes are increased. This is related to the quasi-bound states within the energy gap originated from dichlorocarbene, which are revealed at the large supercell calculation.</P>

      • Properties and current applications of bacterial cyclic β-glucans and their derivatives

        Cho, Eunae,Jeong, Daham,Choi, Youngjin,Jung, Seunho KLUWER ACADEMIC PUBLISHERS 2016 JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHE Vol. No.

        <P>Cyclic beta-glucans are unique constituents that are found in the periplasmic space and extracellular media of Agrobacterium, Rhizobium, Bradyrhizobium, Rhodobacter, Xanthomonas, and Ralstonia species. Based on their glycosidic linkages, they are classified into three groups composed of cyclic beta-(1,2), beta-(1,3)-beta-(1,6), and beta-(1,2)-alpha-(1,6) linked glucans. Their degrees of polymerization vary ranging from 10 to 40 glucose residues, and the backbone structure can be modified with non-sugar moieties. Since the macrocyclic oligosaccharides possess their own characteristics such as inherent three-dimensional structures, hydrogen bonding, and complex-forming abilities, various possible applications would be of interest in the field of green chemistry, separation science, pharmaceutical, and food industries. In this review, we have addressed the properties and current applications of bio-sourced cyclic beta-glucans and their derivatives.</P>

      • Endoscopic Variceal Ligation Induced Ulcer Bleeding: What Are the Risk Factors and Treatment Strategies?

        ( Eunae Cho ),( Chung Hwan Jun ),( Sang Woo Park ),( Min Kee Han ),( Chang Hwan Park ),( Hyun Soo Kim ),( Sung Kyu Choi ),( Jong Sun Rew ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: To determine the risk factors of endoscopic variceal ligation (EVL) induced ulcer bleeding Methods: A total of 430 patients who had undergone EVL in Chonnam National University Hospital from January 2014 to October 2016 were reviewed. EVL was performed for prophylaxis or acute hemorrhage. The patients were classified into two groups: a bleeding group (n=33) and a non-bleeding group (n=397). The patients who had endoscopically confirmed EVL induced ulcer bleeding were included in the bleeding group. The patients without any bleeding sign after the EVL were included in the non-bleeding group. Data including baseline clinical characteristics, endoscopic findings, treatment methods for EVL induced ulcer bleeding, and clinical outcomes were collected and analyzed. Results: EVL induced ulcer bleeding occurred in 7.7% (n=33) of the patients. There were more patients with hepatitis C virus infection (21.3% vs. 13.1%, P=0.005), Child-Pugh classification C (36.4% vs. 13.9%, P=0.008), and concomitant gastric varix form 3 (GV F3) (30.3% vs. 11.8%, P=0.012) in the bleeding group. Initial prothrombin time (PT index, %), Child-Pugh score, Model for end-stage liver disease (MELD) score were associated with EVL induced ulcer bleeding (P=0.026, P< 0.05, and P=0.022, respectively). More bleeding related death was observed in the bleeding group (27.3% vs. 3.6%, P=0.005). In multivariate analysis, MELD score > 10 [OR: 3.42, 95% CI: 1.10-10.64], concomitant GV F3 [OR: 14.1, 95% CI: 2.84-71.43], and detachment of o-ring bands on follow-up endoscopy [OR: 8.06, 95% CI: 2.55-25.64] were independent predictive factors of EVL induced ulcer bleeding. In regarding to treatment methods of EVL induced ulcer, various endoscopic modalities were tried for hemostasis [EVL in eight cases (24.2%), endoscopic variceal obturation (EVO) with cyanoacrylate in 6 cases (18.2%), argon plasma coagulation (APC) in one case (3%), Sengstaken-Blakemore (SB) tube in 3 cases (9.1%), and proton pump inhibitor (PPI) only in 15 case (45.5%)]. Conclusions: MELD score> 10, concomitant gastric varices F3, and detachment of o-ring bands on follow-up endoscopy are risk factors for EVL induced ulcer bleeding.

      • A dimyristoyl phosphatidylcholine/polydiacetylene biomimetic assembly for the selective screening of progesterone

        Cho, Eunae,Hu, Yiluo,Choi, Youngjin,Jung, Seunho Elsevier 2018 Journal of industrial and engineering chemistry Vol.63 No.-

        <P><B>Abstract</B></P> <P>We have reported a hybrid polymer composite, consisting of a supramolecular assembly of polydiacetylene (PDA) and phospholipid, that undergoes chromatic and fluorogenic changes after specific interactions with progesterone, the pregnancy hormone. Progesterone was selectively detected among 10 steroids by the mixed polymer of 1,2-dimyristoyl-sn-glycero-3-phosphocholine and PDA at an optimized ratio of 1:9. The triggering effect of progesterone on the membrane mimetic system were investigated using UV–vis, fluorescence, circular dichroism spectroscopy, Raman scattering, dynamic light scattering, transmission electron microscopy, and computational method. These results offer insight into self-assembly disruption and membrane targeting antibiotics as well as PDA-based sensing technology.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A DMPC/PDA biomimetic assembly is reported as a colorimetric and fluorescent sensory platform for progesterone. </LI> <LI> Progesterone was detected exclusively among 10 different steroid compounds using the biomimetic membrane interface. </LI> <LI> The triggering effect of progesterone on DMPC/PDA membrane mimetic system was evaluated using various analytical tools. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재
      • KCI등재

        Repassivation Kinetics of Fe-20Cr-xNi Alloys (x=0∼80 wt%) and its Relation to Stress Corrosion Susceptibility

        Cho, EunAe,Kwon, HyukSang 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.6

        Repassivation kinetics of rapidly scratched scars on the surface of Fe-20Cr-xNi alloys (x=0∼80 wt%) in a chloride solution was examined using an ampero-chronometric method, and its relationship to stress corrosion cracking (SCC) susceptibility was explored. During the repassivation, passive film initially (0∼10 ms) nucleated and grew according to the place exchange model, and then grew according to the high field ion conduction model. Based on the high field ion conduction model, a new parameter was proposed as a quantitative measure of repassivation rate and hence SCC resistance. Influences of Ni on the repassivation kinetics of Fe-20Cr-xNi (x=0∼80 %) alloys were evaluated in terms of the new parameter, and the results were in good agreement with the influence of Ni on the SCC resistance of the alloys measured in a hot chloride solution.

      • Poster Session : PS 1003 ; Lactulose Breath Test as Prognostic Factor in Irritable Bowel Syndrome

        ( Eunae Cho ),( Jong Sun Rew ),( Hyun Soo Kim ),( Chang Hwan Park ),( Seon Young Park ),( Sung Kyu Choi ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Traditional symptom-based therapies of irritable bowel syndrome (IBS) are directed at the relief of individual IBS symptoms. However, prognostic factors for responses to these treatments have not yet been well studied. The purpose of this study was to evaluate predictors for treatment response in patients with IBS. Methods: A total of 183 patients diagnosed with IBS according to Rome III criteria and underwent lactulose breath test (LBT) from October 2010 to June 2014 were reviewed retrospectively. All participants had checked global IBS symptom questionnaire on the day of the LBT. Overall improvement of global IBS symptoms was reassessed after 4 weeks of treatment. Results: Sixty-one subjects (33.3%) were classified as diarrhea-predominant IBS (IBS-D), 38 (20.8%) as constipation-predominant IBS (IBS-C), 17 (9.3%) as mixed-symptoms IBS (IBS-M), and 67 (36.6%) as unspecifi ed type IBS (IBS-U). LBT results were not signifi cantly different in relation to IBS subtypes. One hundred and nineteen patients (65%) had positive LBT, while 64 patients (35%) had negative LBT. Among the 119 patients with positive LBT, overall symptom improvement was observed in 91 patients (76.5%). Subjects with underlying psychological problems were less likely to have symptom improvement (4/28 vs. 3/91 p=0.031). High basal hydrogen level (>20 ppm) was more frequent in the subjects without symptom improvement (6/28 vs. 6/91, p=0.023). However, underlying psychological problems and high basal hydrogen level were not signifi cantly associated with poor treatment response in patients with negative LBT. Conclusions: High basal hydrogen production correlates with poor treatment response in patients with IBS and positive LBT. This result suggests that LBT can be used as a tool for prediction of treatment response in patients with IBS and positive LBT.

      • Ferrous iron chelating property of low-molecular weight succinoglycans isolated from Sinorhizobium meliloti.

        Cho, Eunae,Choi, Jae Min,Kim, Hwanhee,Tahir, Muhammad Nazir,Choi, Youngjin,Jung, Seunho Rapid Communications of Oxford ; Kluwer Academic P 2013 Biometals Vol.26 No.2

        <P>Iron is an essential nutrient for nitrogen-fixing legume root nodules, and the chelation of ferrous iron plays an important role in the mobility and availability of iron to the legume. In the present study, we investigated the iron-binding properties of low-molecular weight succinoglycans isolated from the nitrogen-fixing bacterium, Sinorhizobium meliloti. The low-molecular weight succinoglycans comprising three monomers (M1-M3), four dimers (D1-D4), and six trimers (T1-T6) of the succinoglycan repeating unit were purified by various chromatographic techniques. Interestingly, the colorimetric ferrozine method showed that the succinoglycans T6, M3, and D3 demonstrated a ferrous iron chelating ability of 83, 63, and 38 % per mg, respectively. The individual binding constants were determined as 43703, 2313, and 760 M(-1) for succinoglycans T6, M3, and D3 using ultraviolet-visible spectroscopy. The complexation of succinoglycan and ferrous iron can cause structural changes, which were analyzed by circular dichroism spectroscopy. Furthermore, the complex could provide antioxidant activity through an anti-Fenton reaction. These results demonstrate that the low-molecular weight succinoglycans can effectively modulate iron biochemistry as a novel ferrous iron-acquisition system of S. meliloti.</P>

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