개구리 皮膚의 伸張度와 X線 全身照射가 이에 미치는 影響

李基錫,朱永恩 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.1

개구리皮膚의 伸張度와 X-線照射가 이에 미치는 影響을 알기 爲하여 腹部 및 背部皮膚에서 各各 矢狀 및 橫斷切片을 作成하여 길이-張力曲線中 彈性의 限界內에서 Hooke의 法則에 따르는 部位에서 Young率을 求 하고 1,000R의 X-線全身照射를 한 後 1,3,5,7 및 10日에서 各各 皮膚切片의 伸張度를 求하여 서로 比較 하였던 바 다음과 같은 結果를 얻었다. 1. 正常개구리의 腹部皮膚의 矢狀 및 橫斷切片의 Young率은 各各 4.09×10 exp (7) dyne/㎠ 및 3.99×10 exp (7) dyne/㎠이었다. 背部皮膚에서 얻은 矢狀 및 橫斷切片의 Young率은 各各 3.69×10 exp (7) dyne/㎠ 및 5.81×10 exp (7) dyne/㎠이었다. 2. X-線 全身照射를 한 群에서 腹部皮膚에서는 그 矢狀切片의 Young率은 照射 3日에서 5.38×10 exp (7) dyne/㎠으로서 가장 높고 그 後는 漸次 낮아지는 傾向을 나타내었고 照射 10日에서는 4.20×10 exp (7) dyne/㎠으로서 正常値에 가까워지는 傾向을 나타내었다. 橫斷切片에서는 照射 3日 및 5日에서 Young率이 各各 4.55×10 exp (7) dyne/㎠ 및 4.50×10 exp (7) dyne/㎠으로서 가장 높고 그後는 第10日까지 次次 낮아진듯하나 그 傾向이 矢狀切片에서 처럼 뚜렷하지 않았다. 3. X-線 全身照射로서 背部皮膚에서는 그 矢狀切片의 Young率은 照射 第3日 및 5日에서 各各 4.25×10 exp (7) dyne/㎠ 및 4.30×10 exp (7) dyne/㎠으로서 높아지는 傾向을 나타내고 그後는 漸次 낮아져서 第10日에서는 正常値와 비슷하게 되는 傾向을 나타내었다. 橫斷切片에서의 Young率도 照射後 第3日 및 5日에서 各各 6.02×10 exp (7) dyne/㎠및 6.00×10 exp (7) dyne/㎠으로서 正常値보다 若干 높은듯 하고 그後는 낮아지는 傾向을 보이나 그 程度가 矢狀切片에서 처 럼 뚜렷하지 못하였다. In an attempt to observe the changes of the distensibility of the frog skin by whole body X-irradiation, the sagittal and transverse strips were excised from the abdominal and back skin of the frog (Rana nigromaculata) following whole body X-irradiation with 1,000R. Young Modulus of the strip was calculated from the length-tension curve of each sample, and a comparison was made with the non-irradiated control group. Experiments were performed on 1,3,5,7 and 10 days after the irradiation, and the results thus obtained are summarized as follows: 1. Young Modulus of the sagittal and transverse strips of the abdominal skin of the normal frog was 4.09×10 exp (7) dyne/㎠ and 3.99×10 exp (7) dyne/㎠, respectively. Young Modulus of the back skin of the normal frog was 3.69×10 exp (7) dyne/㎠ in the sagittal strip, and 5.81×10 exp (7) dyne/㎠ in the transverse strip. 2. Young Modulus of the sagittal strip of the abdominal skin in the irradiated group was the highest (5.38×10 exp (7) dyne/㎠) on the 3rd post-irradiation day, and a tendency of gradual decrease to the normal value on the 10th post-irradiation day was observed. In the transverse strip of the abdominal skin in the irradiated group, the highest values of Young Modulus were observed on the 3rd(4.55×10 exp (7) dyne/㎠) and 5th(4.50×10 exp (7) dyne/㎠) post-irradiation day, and a tendency of gradual decrease till 10th day was observed, but the tendency was not as prominent as in the sagittal strip. 3. A tendency of the elevated values of Young Modulus on the 3rd(4.25×10 exp (7) dyne/㎠) and 5th(4.30×10 exp (7) dyne/㎠) post-irradiation day with the decreasing values to the normal value on the 10th day was observed in the sagittal strip of the back skin of the irradiated frog. In the transverse strip of the irradiated frog, Young Modulus showed a slight increase on the 3rd(6.02×10 exp (7) dyne/㎠) and 5th(6.00×10 exp (7) dyne/㎠) day after the irradiation, but a tendency of decrease was observed thereafter.

생명과학 수업이 유아의 자연친화지능과 과학적 탐구능력에 미치는 영향

이희수,오영희 培材大學校 人文科學硏究所 2011 人文論叢 Vol.28 No.-

The purpose of the study was to provide the basic materials of scientific educational program suitable to young children by showing the effects of life science teaching on young children's naturalist intelligence and scientific inquiring ability. Research issue 1. What are the effects of life science teaching on young children's naturalist intelligence? Research issue 2. What are the effects of life science teaching on young children's scientific inquiring ability? 2-1. What are the effects of life science teaching on the children's ability to predict of the children's scientific investigation? 2-2. What are the effects of life science teaching on the children's ability to observe of the children's scientific investigation? 2-3. What are the effects of life science teaching on the children's ability to classify of the children's scientific investigation? 2-4. What are the effects of life science teaching on the children's ability to measure of the children's scientific investigation? 2-5. What are the effects of life science teaching on the children's ability to discuss of the children's scientific investigation? The target groups of the study are a class of twelve children of 4 years old who are total 24 students of two different day care centers in Daejeon City. The children of the experimental group, A, in one daycare center have been instructed with the life science teaching for the science activity for 16 weeks, while the control group, B, in a different day care center, have been instructed the standard of child care process for the science activity. The measurement of young children's naturalist intelligence and scientific inquiring ability had been used 'the multiple intelligence test (PMIT-E) for preschoolers' and 'the testing instrument of scientific inquiring ability'. To know the difference of their naturalist intelligence between the experimental group and the control group, the research material collected through such a testing instrument had been verified the corresponding sample, t and to know the difference of their scientific inquiring ability, the significance had been verified through the application of ANCOVA. The crucial result on the study is as follows. Firstly, the children who were instructed with the life science teaching statistically significantly improved the young children's naturalist intelligence more than the children who were not instructed with the life science teaching. Therefore, life science teaching has a positive effect on improving young children's naturalist intelligence. Secondly, the result after the study is that the life science teaching has a considerable effect on scientific inquiring ability. The experimental child group experienced a significantly noticeable point increase statistically compared to that of the opposing group. Therefore, life science teaching has a positive effect on improving young children's scientific inquiring ability. Therefore, life science teaching has an effective class on young children's naturalist intelligence and scientific inquiring ability.

“영자의 전성시대”, 1970년대와 ‘청년문화’의 복화술

이민영 ( Lee Min-young ) 우리어문학회 2019 우리어문연구 Vol.63 No.-

In the 1970s, popular culture developed and produced a number of popular films and novels. Contemporary Literature and films are attracting the attention of young people and they got the name of “cheongnyeon munhwa”(Youth Culture) There was clear material symbols in the youth culture, which was represented by acoustic guitar, jeans, and draft beer. However it was difficult to find a unified system of ideas or ideology that tied them together. The contemporary society recognizes the ambiguity of Youth Culture and engages in various controversies to define their cultural identity. In the process of disputation, real youth literature is often criticized. It is because the actual texts of youth literature were regarded as low and unwholesomeness. While the decadent and adaptive attitudes of Youth literature centered on intellectuals were criticized, The Yushin regime regards the youth culture as unhealthy and strengthens the censorship for them. In this paper, it is presupposed that the critical gaze on youth culture is based on the imagined identity of youth in each discourse structure. What I have focused in this article is the novel “The Heydays of Young-ja” (Young-jaui Jeonseongsidae) and the movie “The Heydays of Young-ja” (Young-jaui Jeonseongsidae). These two works are close to the realities of ‘the youth culture without youth people” in that the Hostess appears as the main character in the narrative instead of imagined young man. In addition, the two works show an entirely different narrative structure by applying the media’s specificity precisely. This reveals the development of popular culture since the 1970s when the media characteristics are used precisely, at the same time, it can be said that it embodies the identity of various youth culture that cannot be identified by one name. In this paper, based on the fact that the novel focuses on the narration of the ‘I’ and the movie focuses on the story of ‘Young-ja’, I analyzed the contradictory perception of each work. The narrative of the novel reveals that the voice and the view of the male worker, who were regarded as objects of enlightenment, cannot be coincided with intellectuals. And the narrative of the film represented the passion of the women with the delightful mood, adapting to the censorship process of the authorities, and maximizing the gap between the tragic reality and the cheerful voices. This has led to the discovery of new ways of talking about things that are forbidden.

Comparison of trophic factors changes in the hippocampal CA1 region between the young and adult gerbil induced by transient cerebral ischemia.

Yan, Bing Chun,Park, Joon Ha,Kim, Sung Koo,Choi, Jung Hoon,Lee, Choong Hyun,Yoo, Ki-Yeon,Kwon, Young-Geun,Kim, Young-Myeong,Kim, Jong-Dai,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2012 Cellular and molecular neurobiology Vol.32 No.8

<P>In the present study, we investigated neuronal death/damage in the gerbil hippocampal CA1 region (CA1) and compared changes in some trophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), in the CA1 between the adult and young gerbils after 5 min of transient cerebral ischemia. Most of pyramidal neurons (89%) were damaged 4 days after ischemia-reperfusion (I-R) in the adult; however, in the young, about 59% of pyramidal neurons were damaged 7 days after I-R. The immunoreactivity and levels of BDNF and VEGF, not GDNF, in the CA1 of the normal young were lower than those in the normal adult. Four days after I-R in the adult group, the immunoreactivity and levels of BDNF and VEGF were distinctively decreased, and the immunoreactivity and level of GDNF were increased. However, in the young group, all of their immunoreactivities and levels were much higher than those in the normal young group. From 7 days after I-R, all the immunoreactivities and levels were apparently decreased compared to those of the normal adult and young. In brief, we confirmed our recent finding: more delayed and less neuronal death occurred in the young following I-R, and we newly found that the immunoreactivities of trophic factors, such as BDNF, GDNF, and VEGF, in the stratum pyramidale of the CA1 in the young gerbil were much higher than those in the adult gerbil 4 days after transient cerebral ischemia.</P>

젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality

임정훈,Lee Ga Young,Jeon Yena,Jung Hee-Yeon,Choi Ji Young,CHO, JANG-HEE,Park Sun Hee,김용림,Kim Hyung-Kee,Huh Seung,유은상,Won Dong Il,Kim Chan-Duck 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.3

Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-toold and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14– 7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51–6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients.

수학자 이상설이 소개한 근대자연과학: <식물학(植物學)>

박영민 ( Young Min Park ),김채식 ( Chae Sik Kim ),이상구 ( Sang Gu Lee ),이재화 ( Jae Hwa Lee ) 한국수학교육학회 2011 수학교육논문집 Vol.25 No.2

This paper deals with contents that Sang-Seol Lee contributed to the natural science in the 19th century Korea. Prof. Sung-Rae Park, the science historian, called Sang-Seol Lee Father of the Modern Mathematics education of Korea. Sang-Seol Lee wrote a manuscript Botany with a brush in late 19th century. Botany was transcribed from Science Primers: Botany (written by J. D. Hooker), which is translated into Chinese by Joseph Edkins in 1886. The existence of Sang-Seol Lee`s book Botany was not known to Korean scientists before. In this paper, we study the contents of Botany and its original text. Also we analyze people`s level of understanding Western sciences, especially botany at that time. In addition, we study authors of 16 Primers for Western Knowledge. We study the contribution of mathematician Sang-Seol Lee to science education in the 19th century Korea.

이규보(李奎報) 배율연구(排律硏究)(2) -관인활동(官人活動) 시기(時期)를 중심(中心)으로-

이희영 ( Lee Hee Young ) 한국어문학국제학술포럼 2020 Journal of Korean Culture Vol.48 No.-

This study set out to investigate the creative patterns of Baeyul by Lee Gyu-bo during the years of his positions in the government under the goal of understanding his Baeyul creations throughout his life. During the period, Lee created Baeyul works of Bongjeung to escape from the formal situations happening in exchanges with government officials in a high rank and his unfavorable condition of demotion, thus taking advantage of Baeyul's merits in the poetic style, which allow one to deliver his or her intention respectfully while keeping the formality in a situation of clear objects and goals. During the period, Lee also sought after the diversification of his topics, making use of Baeyul in Jeyeong, Yeongmul, and Heejak, which indicates that Baeyul was free in its operation from an environment of limited topics and certain environments. This shows that Lee's maturity in poetic creation reached a certain level. Finally, he also used Baeyul in various aspects of his daily life during the period, which shows that he regarded Baeyul as a poetic style that he could choose in every aspect of his life whenever it was required. At the root of his creations was his faithful acquisition of the flow among the poets of the previous generations from Du Fu to Bai Juyi who grew out of the old framework of court literature and used Baeyul as a daily poetic style.

이규보(李奎報) 배율연구(排律硏究)(3) - 치사(致仕) 이후(以後)를 중심(中心)으로

이희영 ( Lee¸ Hee-young ) 한국어문학국제학술포럼 2021 Journal of Korean Culture Vol.54 No.-

This study set out to examine the patterns of Lee Gyu-bo(1168-1241)'s creative world in his metrical poems after his resignation. After resigning from office, Lee showed a tendency of creating metrical poems as a means of seeking social intercourse rather than expressing his feelings. He wrote metrical poems at gatherings of Jwajus and Munsaengs, events such as Nakseongsik, and ceremonial situations demanding Bongjeung, trying to reveal solemn emotions and convey his respect for others. Next, he also created metrical poems in the process of Chawoonsangsu with his colleague literary men and fellows that he worked with at the royal court, trying to share honest feelings with them. He exhibited his long relationships, closeness and situations with others in various forms of Daejang. Finally, Lee had a tendency of using metrical poetry as a means of intellectual play. Since the poetic style of metric poems uses Daejang consecutively, they become prolonged in Pyeonpok or impose a huge burden on others through the addition of Hoimunche. Lee continued to write long Hoimuns and metrical poems and even series of metrical poems in old age, which indicates that he found enough joy in the process of writing a poem to forget about his physical difficulties. The findings of the study confirm Lee's tendency of getting the vitality of life and enjoying intellectual play as entertainment by exchanging poems with his colleagues.

<포의교집(布衣交集)>의 ‘초옥(楚玉) 서사’ 구성 과정 연구

이주영(Lee Ju young) 한국고전연구학회 2017 한국고전연구 Vol.0 No.36

이 논문은 <포의교집>의 서사를 ‘초옥에 관한 서사’라고 규정하고, 그것이 구성되는 과정을 탐색하였다. 초옥은 적극적으로 자신의 욕망을 표출하고 실현하고자 하는 인물이다. 그녀는 진정한 선비와 포의지교(布衣之交)를 맺고 자신의 시재(詩才)를 인정받기를 열망한다. 이 열망은 역사서와 유교 경전(經典), 시집, 전기(傳奇)소설 등 한문(漢文) 교양에 의해 형성된 것이다. 궁녀로서의 이력과 허난설헌(許蘭雪軒) 같은 여성 시인에 대한 선망이 그녀의 내면에 영향을 끼치고 정체성을 형성했다. 초옥과 이생의 사귐에는 주변인들의 전언(傳言)과 풍문(風聞)이 개입한다. 이를 통해 초옥의 시재(詩才), 초옥의 언행, 초옥을 둘러싼 사건의 전말이 드러난다. 외모와 재주가 빼어난 초옥은 사람들의 시선과 말 속에서 이미지가 규정되고 구성되며, 이를 통해 ‘초옥에 관한 이야기’가 만들어진다. 그런데 전언과 풍문에는 진실과 거짓이 섞여 있으며, 이생은 초옥에 대한 거짓말을 믿어버리기도 한다. 주변인들은 주인공들이 어떤 선택을 하도록 부추기기도 하고 이들의 관계에 직접 개입하여 사건을 일으키기도 한다. 장사선(張士先)은 이 중 가장 큰 역할을 하는 인물이다. 초옥은 유부녀의 처지로 이생과는 거리낌없이 사귀었으면서도 젊고 부유한 중약의 구애는 거절하고 남편에게 항거해 자살까지 시도한다. 초옥에 대한 소문은 서울 시정(市井)에서 유명한 이야기가 된다. 이생과 초옥은 고종(高宗)과 민비(閔妃)의 가례(嘉禮)를 준비하던 예조(禮曺)의 뜰에서 재회한다. 유부녀임에도 불구하고 여령(女伶)으로 뽑혀와 정절을 빼앗길 처지에 놓인 초옥을 이생이 구해준다. 초옥은 많은 사람들 앞에서 기생들과의 문답을 통해 이생과의 만남에 대한 자신의 입장을 밝힌다. 사람들은 초옥의 외모와 재주, 태도를 칭찬하고 감화(感化)된다. 그러나 이 직후 서양 오랑캐의 침입, 즉 병인양요(丙寅洋擾)의 혼란 속에 초옥의 소식이 끊기게 된다. 이러한 특징은 1864년 6월부터 1866년 6월 사이의 서울이라는 독특한 시공간적 배경과 관련이 있다. 이 시기는 500년을 이어온 조선이 내부의 체제 정비와 서구(西歐)의 침략에 의해 변화를 겪던 시기이다. ‘초옥 서사’는 이러한 변화와 맞물려 지난 시기 조선을 지탱해오던 가치관에 균열이 생긴 것을 드러내는데, 이 작품의 창작은 ‘초옥 이야기’의 또 다른 형식으로의 전언과 풍문에 해당하는 것이다. This study defines the narration of <Po-eui-gyo-jip(布衣交集)> as that about Cho-ok(楚玉) and investigated the process to compose it. Cho-ok is the character who tries to actively expose and achieve her desire. She has been aspiring to have ‘Po-eui-ji-gyo(布衣之交)’ with a true classical scholar and hoped that her materials of poetry will be recognized. This aspiration has been formed by the Chinese classics such as histories, Confucian scriptures, collections of poems and romance novel(傳奇小說). Her envy for female poets such - for example, Heo Nan-seol-heon(許蘭雪軒) - as well as her history as a maid of honor influenced her inner world and formed her identity. The friendship between Cho-ok and Lee-Saeng(李生) is intervened by messages and rumors of surrounding people. Through this, her materials of poetry, the characters words and behaviors and whole story about Cho-ok are disclosed. The images of Cho-ok, who is outstanding for appearance and talent, are defined and composed by the perspectives and words of people. However, both the message and rumor include the truth and falsehood, and Lee-Saeng sometimes believes falsehoods about Cho-ok. The surrounding people incites the characters to make a selection, directly intervenes their relationship, and cause incidents. Jang Sa-Seon(張士先) plays the biggest role among them. Even though Cho-ok dates Lee-Saeng as a married woman, she rejects the courtship of Jung-Yak(仲約) and attempts to commit a suicide, resisting against her husband. The rumor about Cho-ok becomes a famous story in the Seoul. Lee-Saeng and Cho-ok meet again at the garden of the Ministry of Rites(禮曺) preparing for the wedding ceremony of Emperor Gojong(高宗) and Queen Min(閔). In spite of her status as a married woman, Lee-Saeng, whose standing is raised, saves Cho-ok, who is about to lose her chastity after being selected as a Yeonyeong(女伶) . In front of many people, Cho-ok makes her position clearly related to Lee-Saeng through questions and answers with giseng(妓生)s. But in the invasion of the Western barbarians , namely the chaos of Byengin Yangyo(丙寅洋擾), only unproved rumors about Cho-ok circulate. This is related to the unique spatiotemporal background of Seoul between Jun. 1864 and Jun. 1866. This period is in the changes by the Western invasion as well as the interior system maintenance of Chosŏn Dynasty with the history of 500 years. The Cho-ok narration in compliance with these changes reveals the crack of the values that supported Chosŏn Dynasty, and the creation of this work as a novel style of story about Cho-ok corresponds to messages and rumors.