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還魂散(內消散) 물 엑스 및 20% 에탄올 엑스의 消炎, 鎭痛, 抗菌作用에 관한 硏究
金鍾翰,黃忠演,林圭庠 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1
These experiments were conducted to investigate the anti-inflammatory, analgesic and anti-bacterial activity of Hwanhonsan(HHS) water ext. and 20% EtOH ext. The results were summarized as follows ; The inhibitory effect on the leakage of evans blue into peritoneal cavity was significantly increased by HHS water ext. and EtOH ext, respectively. The paper disk granuloma formation displayed more potent effcet than the control group in EtOH ext. Mouse paw edema induced by histamine was significantly decreased by HHS water ext. and EtOH ext. HHS water ext. and EtOH ext. inhibited the protein exudation in rats. The analgesic activity on 0.7% acetic acid induced writhing syndrome was significantly shown by EtOH ext. Anti-bacterial activity was shown by HHS water ext. and EtOH ext., respectively.
최경순,황연숙,정지영 신라대학교 자연과학연구소 1999 自然科學論文集 Vol.6 No.-
This study aims to grasp the present condition of nurseries, to investigate and analyse case studies, to suggest standards and reform measures, and based on these, to produce basic information for the formation of an architectural spatial model. Data were collected through questionnaire survey including observations and interviews. The sample consisted of 82 Child Care Centers. The data were analized by using SPSS-PC program. The major findings were as follows : (1) The facility and equipments in the child care centers were insufficient for children's development. (2) Most of child care centers are not in the desirable Interior environment. To enhance the quality of child care centers, the physical interior environment of child care centers should be influence on the development of child. (3) Functional spaces should be organized to support the child' behavior. Multi-purposed room should be provide to encourage and adapt to variety of large-muscle activities. (4) Interior findings looks too monotonous and do not have characteristics. Natural materials, various colors and patterns are recommendable. Furniture should be designed to meet the functions of flexibility, mobility, and security.
Hwang, Chung Yeon,Cho, Byung Cheol Society for General Microbiology 2008 International journal of systematic and evolutiona Vol.58 No.1
<P>Two novel Gram-negative bacterial strains, designated CL-GR15(T) and CL-GR35, were isolated from coastal seawater of the east coast of Korea. Identical 16S rRNA gene sequences were found in the two strains, and it was found that the strains represented a distinct and deep evolutionary lineage of descent in the order Rhizobiales, and clustered with yet-uncultured marine bacteria. This lineage could not be associated with any of 12 known families in the order Rhizobiales. The most closely related established genus was Ochrobactrum (90.7-92.5% sequence similarity) in the family Brucellaceae. Cells of the strains were facultatively anaerobic, weakly motile rods which occasionally exhibited cohesion with each other. The strains were catalase-, oxidase- and gelatinase-positive, and accumulated intracellular poly-beta-hydroxybutyrate granules. Ubiquinone 10 was the major quinone. The major polar lipids comprised phosphatidylcholine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylmonomethylethanolamine, an unidentified aminolipid and an unidentified glycolipid. The cellular fatty acids mainly consisted of C(18:1)omega7c, summed feature 3 (C(15:0) iso 2-OH and/or C(16:1)omega7c) and C(20:1)omega7c. The DNA G+C content was 52.8-53.0 mol%. DNA-DNA hybridization experiments revealed high values (>97%) for relatedness between strains CL-GR15(T) and CL-GR35 and suggested that these two strains constituted a single species. The distinct phylogenetic position and combinations of genotypic, phenotypic and chemotaxonomic characteristics support the proposal of Cohaesibacter gen. nov., with the type species Cohaesibacter gelatinilyticus sp. nov. (type strain, CL-GR15(T)=KCCM 42319(T)=DSM 18289(T)). Cohaesibacteraceae fam. nov. is also proposed.</P>
Distribution of Antimicrobial Resistant Gram-Negative Bacteria Among the Four Major Rivers in Korea
Yeon Soo Chung,Jae Won Song,Hye Rim Park,Joo Yeon Park,Eun Kang,Sun Young Hwang,Young Kyung Park,Ka Hee Kwon,Seong Han Bae,Sook Shin,Yong Ho Park,Jang Won Yoon 대한수의학회 2012 대한수의학회 학술대회발표집 Vol.2012 No.-
Hwang, Chung Yeon,Lee, Inae,Cho, Yirang,Lee, Yung Mi,Jung, You-Jung,Baek, Kiwoon,Nam, Seung-Il,Lee, Hong Kum International Union of Microbiological Societies 2015 International journal of systematic and evolutiona Vol.65 No.5
<P>A Gram-stain-negative, rod-shaped and non-motile strain, designated PAMC 27266<SUP>T</SUP>, was isolated from deep-sea sediment of the Arctic Ocean. Analysis of the 16S rRNA gene sequence of strain PAMC 27266<SUP>T</SUP> showed closest affiliation with the genus <I>Sediminicola</I> . Phylogenetic analyses revealed that strain PAMC 27266<SUP>T</SUP> formed a robust clade with <I>Sediminicola luteus</I> CNI-3<SUP>T</SUP>, with which it shared 98.9 % 16S rRNA gene sequence similarity. Genomic relatedness analyses based on the average nucleotide identity and genome-to-genome distance showed that strain PAMC 27266<SUP>T</SUP> is clearly distinguished from <I>S. luteus</I> . Cells of strain PAMC 27266<SUP>T</SUP> grew optimally at 15 °C and pH 6.5–7.5 in the presence of 3.5 % (w/v) sea salts. The major polar lipids were phosphatidylethanolamine, two unidentified aminophospholipids and two unidentified lipids. The only respiratory quinone was menaquinone-6. The major cellular fatty acids (>10 %) were C<SUB>16 : 1</SUB>ω6<I>c</I> and/or C<SUB>16 : 1</SUB>ω7<I>c</I> and C<SUB>15 : 0</SUB>. The genomic DNA G+C content was 37.9 mol%. Based on the phylogenetic, genomic, chemotaxonomic and phenotypic data presented, we propose strain PAMC 27266<SUP>T</SUP> ( = KCCM 43038<SUP>T</SUP> = JCM 19894<SUP>T</SUP>) as the type strain of a novel species, with the name <I>Sediminicola arcticus</I> sp. nov.</P>
( Mi Yeon Chung ),( Dae Won Jun ),( Young Hwan Hwang ),( Yeon Hwa Yu ),( Byoung Kwan Son ),( Seong Hwan Kim ),( Yun Ju Jo ),( Young Sook Park ),( Oh Young Lee ) 대한소화기기능성질환·운동학회 2009 Journal of Neurogastroenterology and Motility (JNM Vol.15 No.2
Background/Aims: Delayed orocecal transit time (OCTT) and presence of small intestinal bacterial overgrowth (SIBO) may contribute to the common gastrointestinal symptoms in patient with cirrhosis. However, not much is known how SIBO and OCTT would affect gastrointestinal symptoms in cirrhotic patients. The objective of this study was to investigate the correlation of SIBO, OCTT and gastrointestinal symptoms in cirrhotic patients. Methods: The lactulose breath test was used to measure SIBO and OCTT on 40 cirrhotic patients and 40 healthy volunteers. A questionnaire was completed in 40 cirrhotic patients. Results: SIBO was diagnosed on 23 (57.7%) of 40 cirrhotic patients and on 11 (27.5%) of 40 controls (p=0.012). SIBO positive patients showed higher constipation score (1.30 vs. 0.47, p=0.05) and hard stool score (0.87 vs. 0.18, p=0.02) than SIBO negative patients. OCTT was slower in cirrhotic patients compared to healthy controls (140±29 min vs. 116±20 min, p=0.001) and slower in SIBO positive group compared to SIBO negative group (136±25 min vs. 120±28 min, p=0.035). Delayed OCTT was associated with hard stool score (r=0.44, p=0.02). Conclusions: Delayed OCTT and higher prevalence of SIBO were noted in cirrhotic patients. SIBO positive cirrhotic patients showed higher constipation score and hard stool score than SIBO negative patients.(Korean J Neurogastroenterol Motil 2009;15:116-123)