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정진혁,김기태,정승규 대한비과학회 2008 Journal of rhinology Vol.15 No.2
In recent years, dental implants have become a frequently performed procedure in most dental clinics. The edentulous posterior maxilla provides a limited amount of bony volume due to atrophy of the alveolar ridge and pneumatization of the maxillary sinus. Consequently, dental implant placement in the posterior maxilla can be complicated and it becomes a matter for the otolaryngology field. However, for most otolaryngologists, knowledge of dental implantation is scarce. Therefore, consensus on the diagnosis and treatment associated with dental implants is needed. During consultation, before a dental implant, a nasal endoscope and paranasal sinus CT scan should be taken and any mucosal thickening, incidental polyps, acute sinusitis, chronic sinusitis, or malignancy should be differentiated and treated as needed. After the dental implant, acute sinusitis and migration of the dental implant into the maxillary sinus can occur because of damage to sinus mucosa or a foreign body reaction. These complications can be evaluated and treated more easily by an otolaryngologist than by a dentist. Nasal endoscopy and endoscopic sinus surgery can be applied to problems associated with dental implants. In recent years, dental implants have become a frequently performed procedure in most dental clinics. The edentulous posterior maxilla provides a limited amount of bony volume due to atrophy of the alveolar ridge and pneumatization of the maxillary sinus. Consequently, dental implant placement in the posterior maxilla can be complicated and it becomes a matter for the otolaryngology field. However, for most otolaryngologists, knowledge of dental implantation is scarce. Therefore, consensus on the diagnosis and treatment associated with dental implants is needed. During consultation, before a dental implant, a nasal endoscope and paranasal sinus CT scan should be taken and any mucosal thickening, incidental polyps, acute sinusitis, chronic sinusitis, or malignancy should be differentiated and treated as needed. After the dental implant, acute sinusitis and migration of the dental implant into the maxillary sinus can occur because of damage to sinus mucosa or a foreign body reaction. These complications can be evaluated and treated more easily by an otolaryngologist than by a dentist. Nasal endoscopy and endoscopic sinus surgery can be applied to problems associated with dental implants.
정진혁,공혜영(Gong, Hye-Yeong) 대한교통학회 2007 대한교통학회 학술대회지 Vol.57 No.-
개인이 여러 가지 활동에 어떠한 방식으로 시간을 배분하는가를 규명하기 위하여 많은 연구가 이루어졌다. 그 중 가장 주목할 만한 것은 효용이론에 바탕을 두고 개인은 사용가능한 시간을 모든 활동으로부터 창출되는 효용이 극대화하는 방향으로 배분한다는 가정을 한 것이었다.(Kitamura,1983) 그에 따라 목적지 선택 모형이나 활동시간예측모형에서 각 목적지별, 활동별, 개인별 효용을 미리 정의하고 제약조건하에서 개인이 활동을 통해 얻는 효용을 극대화시키는 해를 찾고자 하였다. 그러나 효용은 해당일의 상황과 필요에 의해 달라질 수 있으며 개인의 사회경제적 속성으로 그룹을 지어 효용을 정의할 경우 활동자체의 특성이나 같은 날 발생한 다른 활동들의 영향을 고려하지 못할 수 있다.
정진혁,김영훈,송태준,안효선,Kyu Dae Kim,In Bo Kim,윤택준,김종배 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.3
To determine Korean mistletoe lectin (KML-C)functions as a mucosal adjuvant, we monitored its ability to modulate the immune response after intranasal immunization with hemagglutinin (HA) as an antigen. Mucosal and systemic immune responses with KML-C were compared to responses with cholera toxin B subunit (CTB) as an adjuvant. Intranasal co-administration of HA and KML-C in mice resulted in increased anti-HA antibody titers in both vaginal wash and serum. Isotyping analysis revealed that KML-C augmented HA-specific antibody titers of IgG1, IgG2a, and IgG2b isotypes. More than 5-fold of interleukin 2 (IL-2), 3-fold of interferon-γ (IFN-γ) , and 4-fold of granulocyte macrophage colony-stimulating factor (GM-CSF) mRNA were detected using real time PCR in splenocytes of mice immunized with HA plus KML-C. Fluorescence activated cell sorting (FACS) analysis indicated that co-administration of KML-C increased the subpopulation of CD3/CD8 double positive T cells (16.4%)than control (10%). Taken together, these data demonstrate that KML-C has the ability to serve as a mucosal adjuvant.