The Korea Herald Headline 분석 : Aspect를 중심으로

이지윤,이치명 이화여자대학교 인문과학대학 영어영문학과 2001 Minerva Vol.- No.28

Lazertinib: on the Way to Its Throne

이지윤,홍민희,조병철 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.9

Lazertinib is an oral, irreversible, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) thatforms an irreversible covalent bond to the Cys797 residue in the ATP-binding site of the EGFR kinase domain and exhibits a highselectivity for sensitizing and T790M EGFR mutations. In January 2021, it was first approved for the treatment of advanced ormetastatic non-small cell lung cancer (NSCLC) patients with EGFR T790M who had previously received EGFR TKI therapy basedon LASER201, a phase I/II trial. At a recommended dose of 240 mg, lazertinib achieved an encouraging anti-tumor activity in bothextra- and intracranial lesions. With a high half-maximal inhibitory concentration for EGFR wildtype tumors, it is anticipated topose a lower risk of skin and cardiac adverse events compared to osimertinib. Lazertinib is currently being investigated as a mono-therapy in first-line treatment and in combination with amivantamab under various settings. In this review, we systematically sum-marize the preclinical and clinical data of lazertinib and discuss future perspectives on the treatment of EGFR-mutant NSCLC.

소크라테스 대화법 관련 교육연구 현황 분석: 2015년-2022년까지

이지윤,정대련 학습자중심교과교육학회 2024 학습자중심교과교육연구 Vol.24 No.4

Objectives This study aims to analyze the current state of educational research related to the Socratic Dialogue method, particularly in the context of the upcoming implementation of the revised 2022 curriculum. Methods The study involved analyzing 130 scholarly articles and thesis related to the Socratic method in education, published between 2015 and December 2022. Initially, the research classified by the types of studies according to school grades and research methods to analyze their current state. For a more comprehensive analysis, the study further categorized research types based on content, examining the status of applied subjects, research topics, and the use of literature and models. Results Firstly, the research types were predominantly literature studies. In particular, literature studies were prevalent in joint or elementary and high school-targeted research, while quantitative studies were common for early childhood and qualitative studies for middle school. Secondly, out of 130 studies related to the Socratic method, 72 were classified as basic research, mainly focusing on ‘general education’ and ‘moral’ subjects. In practical research, ‘moral’ and ‘philosophy’ subjects were commonly applied, especially ‘philosophical (community of inquiry activities)’ for early childhood education. Thirdly, upon reviewing the literature and models used in the research, basic research most frequently utilized ‘Dialogues’, focusing on educational implications like ‘teaching methods’⋅’teacher's role’⋅‘educational objectives’⋅‘content’. They emphasized educational objectives such as ‘truth-seeking’⋅‘knowledge’⋅‘unity of knowledge and action’⋅‘wisdom’, using key concepts from the ‘Dialogues’ and frequently analyzing the Elenchos method of Socratic dialogue. In practical research, over 50% reported results from conducting philosophical inquiry community activities. Conclusions This study is significant as it reviews the current state of educational research related to the Socratic method since the 2015 curriculum revision, in anticipation of the implementation of the revised 2022 curriculum (in 2024). It provides foundational research material for the qualitative improvement of subsequent studies and suggests future directions.

제올라이트 이산화탄소 흡착제의 개질 방안 연구

이지윤,조영민,권순박,박덕신 한국대기환경학회 2010 한국대기환경학회 학술대회논문집 Vol.2010 No.10월

전북지역 대학생의 소셜미디어 이용동기 유형에 따른 체중조절 행태 연구

이지윤,정성석,노정옥 한국영양학회 2023 Journal of Nutrition and Health Vol.56 No.2

Purpose: This study examines the weight control behavior depending on university students’ motives of using social media. Methods: The participants were 447 university students in the Jeonbuk area. Collected data were analyzed using factor analysis, cluster analysis, analysis of variance, and χ2 tests with SPSS v. 26.0. Considering the motives of using social media, we investigated the usage of social media, dietary behavior related to social media, and weight control behavior. Results: Using the K-clustering method, the motives to use social media were categorized into three clusters: cluster 1 was the interest-centered group, cluster 2 was the multipurpose information-seeking group, and cluster 3 was the relationship-centered group. Among the various social media sites, YouTube (86.8%), Instagram (76.1%), and Facebook (61.1%) were the most visited by the subjects. The dietary behavior related to social media in cluster 2 was significantly higher than clusters 1 and 3 (p < 0.001). Clusters 1 and 2 showed a significantly higher dissatisfaction with one’s weight (p < 0.05) and consequent interest in weight control than cluster 3 (p < 0.001). Cluster 2 used weight control-related information from social media significantly more than other clusters (p < 0.05). Weight control experiences in cluster 1 and 2 were significantly higher than in cluster 3 (p < 0.001). Conclusion: Differences in dietary behavior related to social media and weight control behavior were observed between cluster types of motivation to use social media. Based on the usage motives of university students and their behaviors, we propose that educational programs should be conducted for weight control using social media.

티몬․위메프 사태의 재무관리적 분석: 유동성 관리 실패와 도덕적 해이

이지윤 한국재무관리학회 2024 재무관리연구 Vol.41 No.5

본 연구는 최근 이커머스 업계에서 발생한 대규모 미정산 사태인 티몬․위메프 사건을 재무관리적 관점에서 분석하고 그 대책을 모색한다. 본 사태의 주요 원인으로 유동성 관리 실패와 경영진의 도덕적 해이를 제시한다. 이러한 문제는 이커머스 업계만의 특수한 문제가 아니기 때문에 대책의 마련에 있어 이커머스 업계 전반에 대한 규제 강화보다는 재무관리적 접근이 효율적일 것임을 강조한다. 유동성 관리 실패로 인한 피해 확산 및 도덕적 해이 문제를 방지하기 위한 대책을 제안하나, 규제는 재무 건정성이 취약한 곳에 집중할 것을 권장한다. 본 연구는 이커머스 업계의 신뢰성 확보를 위한 규제가 필요할 수 있으나 업계의 혁신을 저해하지 않는 유연한 경영 환경 마련의 필요성을 강조하며, 해외 기반 이커머스 기업에 대한 법적 책임 문제에도 주의를 기울여야 함을 지적한다.

초단시간 기상 예측을 위한 역학 모델의 도입 및 개선 계획

이지윤,정성훈,한상옥,이희상 한국기상학회 2008 한국기상학회 학술대회 논문집 Vol.2008 No.-

A New Approach for Glutinous Rice Breeding through Dull Genes Pyramiding

이지윤,강주원,조수민,권영호,이소명,신동진,송유천,박동수,이종희,고종민,조준현 한국육종학회 2020 Plant Breeding and Biotechnology Vol.8 No.4

Glutinous rice is a key grain quality trait occupying an important part during rice processing in most rice growing areas. In this study, a gene pyramiding approach was used to introduce two dull genes, responsible for low amylose content, for glutinous ricebreeding using marker assisted selection (MAS). The genotyping results revealed that rice cultivar Milyang319 carries both dull geneson chromosome 6, derived from cv. Milky-queen (Wx-mq) and cv. LGS-soft (du12(t)), respectively. Milyang319 had a significantlylow amylose content (9.0%) compared to those observed in donor parents Milky-queen (15.7%) and LGS-soft (14.5%). In addition, theamylogram analysis of Milyang319 showed a similar pattern of glutinous rice. Originally, Milyang319 had a low hardness and morestickiness compared to those recorded in cooked rice of both dull parental lines. Therefore, Milyang319 is proposed as a promisingcandidate rice cultivar that could be used as a new source of waxy germplasms with same physicochemical features of glutinous rice infurther breeding programs.

항공 산업의 ESG 활동 체계화를 위한 토픽모델링 분석

이지윤 한국항공경영학회 2024 한국항공경영학회지 Vol.22 No.5

This study aims to conduct a systematic analysis of Environmental, Social, and Governance (ESG) activities in the aviation industry and elucidate the common ESG elements prioritized by major airlines. Employing text mining techniques, we examined ESG and sustainability reports from 21 major airlines selected from the world’s top 100 carriers. The analytical corpus consisted of 294,308 English texts, systematically categorized into environmental (90,903), social (130,949), and governance (72,456) domains. The methodological framework incorporated Term Frequency-Inverse Document Frequency (TF-IDF) analysis and Latent Dirichlet Allocation (LDA) topic modeling to extract latent themes. The LDA analysis revealed distinct thematic clusters within each ESG domain. The environmental sphere yielded ‘energy conservation’, ‘carbon emission reduction’, and ‘carbon emission policies’ as predominant topics. The social domain exhibited ‘human resource management’ and ‘customer safety’ as primary themes, while the governance sector demonstrated ‘risk management’, ‘risk management systems’, ‘governance transparency’ and ‘operational efficiency’ as salient features. These empirical findings suggest that the ESG initiatives of the examined airlines are fundamentally structured around carbon emission management in environmental policies, human capital and safety protocols in social dimensions, and risk management frameworks in governance structures. A significant observation is the conspicuous absence of Corporate Social Responsibility (CSR) elements, particularly philanthropic activities, within the social domain. This research contributes to the academic literature in several dimensions: it advances methodological frameworks through the implementation of text mining techniques in ESG research, underscores the imperative for establishing standardized ESG evaluation criteria specific to the aviation sector, and documents the strategic evolution and integration of ESG practices in the airline industry. Furthermore, the study provides actionable implications across environmental (carbon emission management), social (human resource and safety management), and governance (risk management system implementation) dimensions, thereby facilitating the development of comprehensive ESG strategies in the aviation sector.

전통 노리개에 사용된 보석의 현대적 변용 연구

이지윤,정양희 한국귀금속보석학회 2013 한국귀금속보석학회지 Vol.7 No.4

인류의 역사와 함께 성장해온 장신구는 단순히 몸을 아름답게 치장하기 위해서 뿐 아니라 자신의 사회적 지위와 신분을 나타내기 위해서 또는 간절한 염원이나 신앙을 담은 도구로 사용되었다. 그렇기 때문에 장신구에는 그 민족의 미의식과 생활관, 문화, 사회성이 내재되어 있다고 해도 과언이 아니다. 선사시대, 삼국시대를 지나면서 우리 선조들은 화려하면서도 다양한 종류의 장신구들을 제작ㆍ착용하였다. 특히 조선시대에는 노리개, 떨잠, 비녀 등의 장신구가 발전하였고 금ㆍ은 등의 금속류와 함께 옥, 산호, 호박 등의 보패류를 사용하여 장신구를 제작하였다. 궁중 왕실에서부터 평민에게까지 전 계층의 여인네들이 즐겨 착용했던 전통 장신구는 외국의 복식ㆍ장식문화의 유입과 함께 큰 변화를 겪게 된다. 즉, 일상에서 늘 착용하던 장신구에서 박물관 전시물, TV사극 속 소품 그리고 장인들의 재연품으로 그 의미가 바뀌게 되었다. 또한 맹목적인 서구형 장신구의 제작과 사용은 우리 고유의 독창성이 담긴 전통 장신구의 발전을 저해하는 요소가 되고 있다. 현대 장신구의 특징은 독특한 재료와 제작기법을 사용하여 제작자와 착용자간의 소통과 착용자의 개성과 미적 감각을 보여주는 수단으로 인식되어 하나의 예술분야로 자리잡고 있는 것이다. 본 연구에서는 전통 장신구 중 노리개를 응용하여 개성과 감성을 중시하는 현대적 장신구로의 변용 가능성과 활용방안을 제시하고자 한다. 노리개는 여성의 가슴을 장식한다는 점에서 현대 여성들이 즐겨 착용하는 브로치, 목걸이와 그 용도가 유사하여 현대적 변용의 활용도가 높을 것으로 간주된다. 또한 노리개에 사용된 보석을 살펴봄으로써 그 속에 담긴 의미와 조형성을 현대 장신구에 접목시켜 장신구 제작 시 보석선택의 폭을 넓힐 수 있는 계기를 마련하고자 한다.