탈지분유 함유 식이를 섭취하는 흰쥐에서 칼슘과 비타민 D 수준이 무기질 대사에 미치는 영향

이경민,이연주,원은숙,이상선,Lee, Kyung-Min,Lee, Yeon Joo,Won, Eun-Sook,Lee, Sang Sun 한국식품영양학회 2014 韓國食品營養學會誌 Vol.27 No.4

The purpose of this study was to investigate the effect of calcium (Ca) and vitamin D (vit. D) levels on metabolism of various minerals such as Ca, P, Mg, Fe, Zn, Cu, and Cr. The comparison was made on the rats that were placed on diet containing powdered skim milk with different Ca and vit. D levels for 5 weeks. A total of 42 5-week-old Sprague-Dawley rats were divided into 7 groups as follows: Control group consisted of normal Ca and normal vit. D (0.5% Ca, 1,000 IU vit. D); Experimental groups were divided into low (0.25%) and high (1.0%) calcium levels; and vit. D group was divided into low (10 IU), normal (1,000 IU), and high (5,000 IU) subgroups. The weight gain and food efficiency ratios of the rats were not significantly different with increasing dietary Ca levels. The absorption rates of 7 minerals (Ca, P, Mg, Fe, Zn, Cu, and Cr) were significantly decreased with increasing dietary Ca levels. Also, fecal excretion of P significantly increased with increasing dietary vit. D levels (p<0.05), and urine excretion of Fe was significantly increased with increasing dietary vit. D levels (p<0.001). The result indicated that higher Ca intake affected on bioavailability of other minerals, due to interactions among minerals in the process of intestinal absorption. However, vitamin D intake had no effect on bioavailability of several minerals. Therefore, it could be suggested that adequate Ca intake is important for balance of the minerals.

위화(胃火) 1호(號)로 호전(好轉)된 만성위염(慢性胃炎) 환자(患者) 치험(治驗) 2례(例)

이경민,이세연,임성철,서정철,한상원,Lee, Kyung-min,Lee, Se-yun,Im, Sung-chul,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6

Objective: This study was designed to investigate the effect of Wihwa herbal-acupuncture on chronic gastritis. Methods: Wihwa herbal-acupuncture was administered two times a week. The following points were selected: CV12(中脘), CV13(上脘), S36(足三里), Liv3(太衝). We checked pain rating score(P.R.S.), visual analogue scale (V.A.S.) and Gastroscopy. Results: After 6 weeks of treatment, the patient showed that clinical symtoms was disappeared, Lee's P.R.S. changed from 77 to 8 and Park's P.R.S. from 55 to 0 and gastric erosion disappeared on gastroscopy. Conclusions: These results suggest that and Wihwa herbal-acupuncture has good effect on chronic gastritis. But further studies are required to concretely prove the effectiveness of Wihwa herbal-acupuncture for treating chronic gastritis.

Proteomic Analysis기법을 이용한 홍화자약침액(紅花子藥鍼液)이 간암세포주(肝巖細胞柱)의 유전자(遺傳子) 발현(發顯)에 미치는 영향(影響)

이경민,임성철,정태영,서정철,한상원,Lee, Kyung-Min,Lim, Seong-Chul,Jeong, Tae-Young,Seo, Jung-Chul,Han, Sang-Won 대한약침학회 2005 Journal of pharmacopuncture Vol.8 No.2

Objective : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as HepG2 hepatoma cells lines. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. For proteomic analysis, total protein was analyzed by 2D gel electrophoresis and Q-TOF mass spectrometer. Results : In proteomic analysis, three spots were identified by 2D-gel electrophoresis and Q-TOF analysis. One down-regulated protein was heat shock 70kDa protein 5 and up-regulated proteins were chaperonin and 2-phospho -pyruvate-hydratase ${\alpha}-enolase$ by 1.5mg/ml of CTF-HAS. Discussion : Proteomic analysis approach were performed to screen the differential expression genes. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.

국립대학도서관 상호대차의 활성화 요인에 관한 연구

이경민,Lee Kyung-Min 한국문헌정보학회 1997 한국문헌정보학회지 Vol.31 No.1

본 연구는 대학도서관 상호대차의 활성화에 영향을 미치는 요인을 맞힐 목적으로 수행되었다. 자료는 (국립대학도서관보)와 질문지를 통하여 수집하였고. 상호대차 활성화 요인의 분석 방법으로는 분석 자료의 형태에 따라 t-test와 회귀분석방법을 사용하여, 21개 국립대학도서관의 구성요소와 상호대차건수와의 관계를 밝혔다. 연구의 결과 상호대차 담당자의 주제 배경이 문헌정보학인 도서관군이 그렇지 않은 도서관군보다 상호대차가 활발하고, 자료는 접수건수에 많은 영향을 미치지만, 의뢰건수에는 접수건수에 비해 비교적 적게 영향을 미치고 있으며, 상호대차시 팩시밀리나 PC를 사용하는 도서관군이 그렇지 않은 도서관군보다 상호대차가 활발하다는 점등이 밝혀졌다. The purpose of this study is to Investigate the factors haying an Influence on activating the Interlibrary loan between national university libraries. Data were collected by <Bulletin of National College & University Libraries> and questionnaires. To analyze the factors activating the Interlibrary loan, 1-test and regression analysis method Is adopted depending on the type of data collected. The findings of the study shows that the interlibrary loan can be more actively performed in the group of libraries to focus the subject background on library and Information science than the other group the number of lending cases is highly affected by collection size. the number of periodical titles, annually increased number of collections and periodical titles. Otherwise the number of borrowing cases is much less affected than the number of lending cases by the above factors : the interlibrary loan can be more actively conducted in the group of libraries using facsimile or PC than the other group.

통비음(通痺飮)과 건요음(健腰飮)의 선호도에 대한 임상연구

이경민,서정철,한상원,임성철,정태영,하일도,변성희,Lee, Kyung-min,Seo, Jung-chul,Han, Sang-won,Leem, Sung-chul,Jeong, Tae-young,Ha, Il-do,Byun, Sung-Hee 대한침구의학회 2004 대한침구의학회지 Vol.21 No.1

Objective: In oriental medicine, development of new formulations has been demanded. But, there are few reports about the improvement of formulations of herbal medicine in Korea. Nowadays soft Ex has been exploited and used comparing with retort pouch. This study was designed to study on preference on TongBiEum(通痺飮)/GunYoEum(健腰飮) and to investigate which OMD(oriental medical doctor) and non-OMD prefer soft Ex or retort pouch. Methods: As pilot study we administerd TongBiEum(通痺飮) once to 30 persons who serviced Gumi Oriental Medical hospital, Daegu Haany University from April 1, 2003 to April 10, 2003. And then we administerd GunYoEum(健腰飮) once to final test group(73 persons) who serviced Daegu, Gumi, Pohang Oriental Medical hospital, Daegu Haany University from April 20, 2003 to May 10, 2003. We made up questionaires about feeling during and after taking medicine, convenience and preference ect. Results: Convenience and preference of soft Ex is significantly different between OMD and non-OMD and in age bracket, but there is no significance between men and women group. Portable state of soft Ex is very convenient, dose of soft Ex is a little amount, color of soft Ex is regular in OMD & non-OMD, men & Women and an age bracket. Conclusions: From above study it was revealed that preference of herbal medicine formulations was significantly different between OMD and non-OMD. So development of new herbal medicine formulations is needed for consumers such as non-OMD.

옻에 대한 문헌적 고찰

이경민,권기록,최성모,김태희,Lee, Kyoung-Min,Kwon, Ki-Rok,Choi, Sung-Mo,Kim, Tae-Hee 대한약침학회 2002 Journal of pharmacopuncture Vol.5 No.1

Objective: It will be examined in this research whether Lacquer poison can be used as an distinguished treatment to cure incurable diseases by considering literature existing and various papers. Method: I studies origin, alias, species, toxicity, effect, treatment, component, medical action and contraindication of Rhus vemiciflua stokes through various kinds literatures. Results: Sap of Rhus vemiciflua stokes that is used for medical purposes, has an effect on anti-tumor, anti-oxidation, hangover cure, and gastritis suppression. Even though urushiol and fIavonoids, the main ingredient of lacquer, has medical cure effects. but urushiol results in a dermatropic allergy. Sincc xylem of a Rhus vemiciflua stokes, however. does not induce the allergy but has medical efficacy, research on this topic is needed.

Oligonucleotide chip를 이용한 홍화자약침액(紅花子藥鍼液)이 간암세포주(肝癌細胞柱)의 유전자(遺傳子) 발현(發顯)에 미치는 영향(影響)

이경민,임성철,정태영,서정철,한상원,Lee, Kyung-min,Lim, Seong-chul,Jung, Tae-young,Seo, Jung-chul,Han, Sang-won 대한침구의학회 2005 대한침구의학회지 Vol.22 No.3

Objective : It has long been known about the osteogenic effect of CTF-HAS on bone tissues. However, it has not been determined the effect of CTF-HAS on cancer cells. The purpose of this study is to screen the CTF-HAS mediated differentially expressed genes in cancer cells such as HepG2 hepatoma cells lines. Oligonucleotide microarray approach were employed to screen the differential expression genes. Methods : CTF-HAS was prepared by boiling and stored at $-70^{\circ}C$ until use. Cells were treated with various concentrations of CTF-HAS(0.1, 0.5, 1.5, 10, $20mg/m{\ell}$) for 24 h. Cytotoxicity was tested by MTT assay. To screen the differentially expressed genes in cancer cells, cells were treated with $1.5mg/m{\ell}$ of CTF-HAS. For oligonucleotide microarray assay, total RNA was used for gene expression analysis using oligonucleotide genechip (Human genome U133 Plus 2.0., Affimatrix Co.). ResuIts : It has no cytotoxic effects on HepG2 cells in all concentrations (0.1, 0.5, 1.5, 10, $20mg/m{\ell}$). More than twofold up-regulated genes were 19 genes. The number of more than twofold down-regulated genes was 13. Discussion : This study showed the screening of CTF-HAS mediated differentially regulated genes using combined approaches of oligonucleotide microarray. The screened genes will be used for the better understanding in therapeutic effect of CTF-HAS on cancer field.

메쉬 직물의 밀도 및 위치변화에 따른 흡음특성

이경민,전두환,전상후,Lee, Kyoung Min,Chun, Du Hwan,Chun, Sang Hoo 한국섬유공학회 2015 한국섬유공학회지 Vol.52 No.3

Sound absorbing materials are generally categorized as porous-type absorbers and panel-type absorbers. In addition, their absorbing mechanism is typically described as a conversion of sound energy into heat energy through the dynamic behavior of the material. Thus one of the important parameters influencing the sound absorption characteristics is the density of the material. This study investigated the sound absorption characteristics of a mesh fabric based on the mesh density and fabric layering structure. Four different mesh densities (130, 180, 200, and 230 T) combined with five different layering structures were investigated to help understand the mechanism and effect of the sound absorption characteristics. The results indicate that a panel-type absorber has better sound absorption characteristics within a lower frequency range, whereas a porous-type absorber performs better at a higher frequency. In addition, the increased fabric density of the mesh fabric shows a better performance in terms of sound absorption. An empirical equation between the sound absorption coefficient and the fabric density was also derived for further design applications.

도서관의 전자정보실 서비스 개선을 위한 이용사례 분석

이경민,Lee, Kyung-Min 한국도서관정보학회 2009 한국도서관정보학회지 Vol.40 No.4

국내 도서관은 정보화 시대에 적응하기 위하여 이용자에게 컴퓨터 사용환경을 일찍부터 제공하였다. 하지만 오늘날은 컴퓨터 사용환경이 일반화되어 전자정보실에 대한 변화가 필요한 시점이다. 이에 문헌정보학과 학생 78명으로 하여금 직접 전자정보실을 이용해 보게 하여 이용에 편리한 점과 불편했던 점을 기술하게 하였다. 이용사례 결과를 분석하여 전자정보실의 바람직한 변화 방향을 찾고자 하였다. 그 결과 사서에 의해 제공되는 정보서비스에서 불만이 가장 많았고, 그 이외에 시설과 장비 그리고 공간 순으로 많았다. 이를 개선하기 위한 방안으로는 도서관에서 전자정보실의 기능을 명확히 하는 미션과 서비스 방향을 정확히 제시하여야 하고, 사서는 전자정보실이 디지털 자료와 아날로그 자료 그리고 정보통신 기술지원이 동시에 제공되는 현대화된 레퍼런스 룸으로 인식해야 할 것이다. The domestic libraries offered users computer environment early to adapt in information age. However, the computer environment is generalized today, so it is needed to change about the role of electronic information room in this point. The author investigated use experience by 78 students who are student in library and information science. They experienced electronic information room and wrote their experience. As a result, they felt most inconvenience in information service of librarians, facilities and equipment and space. To improve the service of electronic information room, it is needed to develop the mission and service policy of electronic information room. And also the librarian must think the room as modern reference room that has digital and analog materials and information technology.

JPEG2000 CODEC을 위한 Entropy 코딩 알고리즘의 VLSI 설계

이경민,오경호,정일환,김영민,Lee, Kyoung-Min,Oh, Kyoung-Ho,Jung, Il-Hwan,Kim, Young-Min 한국통신학회 2004 韓國通信學會論文誌 Vol.29 No.1C

본 논문은 차세대 정지영상 압축방식인 JPEG2000 코덱의 엔트로피 코딩 알고리즘의 하드웨어적 구조를 제안하고, 설계하였다. 구현된 엔트로피 코더는 컨텍스트 기반의 산술부호화기로서 컨텍스트 추출부(CE)와 산술부호화기(AC)로 구성된다. CE는 각 코팅패스에서 코딩에 참여하지 않는 샘플은 skipping 함으로써 동작속도를 향상시켰으며, AC는 MQ coder에 기반을 둔 산술부호화기로서, 곱셈과 나눗셈 연산대신 단순 가감산과 shift 연산망을 이용하여 구조를 단순화하고 연산량을 줄임으로써 동작속도를 향상시켰다. 설계된 엔트로피 코더는 VHDL 모델링후 Xilinx FPGA technology를 이용하여 합성한 후 동작을 검증하였으며, 30MHz의 동작속도를 보인다. In this paper, we design an efficient VLSI architecture of entropy coding algorithm in JPEG2000. Entropy coder is a context-based binary arithmetic encoder, and composed of a Context Extractor(CE) and an Arithmetic Coder(AC). We speed-up CE by skipping no-operation bits in coding passes, and AC is to be performed based on MQ coder. Because of using Qe value associated with each allowed context and probability estimation, MQ coder is a multiplication free coder that reduces computation loads and makes simple the structure of arithmetic coder. We have developed and synthesized the VHDL models of CE and AC pairs using Xilinx FPGA technology. The proposed architecture operates up to 30MHz.