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오지수,김수관,김학균,윤정훈,Oh, Ji-Su,Kim, Su-Gwan,Kim, Hak-Kyun,Yoon, Jung-Hoon 대한악안면성형재건외과학회 2007 Maxillofacial Plastic Reconstructive Surgery Vol.29 No.5
The glandular odontogenic cyst is an uncommon odontogenic cyst as a distinct entity. We reviewed a series of 7 glandular odontogenic cysts of the jaws experienced between 2003 and 2006 at the department of Oral and Maxillofacial surgery, Chosun university. The study group consisted of 3 females (42.9%) and 4 males (57.1%), with an age range of 31 to 75 years and mean age was 58.6 years. The maxilla was involved in 5 cases (71.4%) and the mandible in 2 cases (28.6%). Three cases involved impacted tooth. Clinically 6 cases showed swelling and tenderness. All the lesion presented well-defined unilocular radiolucent lesion radiographically. Provisional clinical diagnosis was varied, incisional biopsy was done in 1 case. Histopathologically, those were lined by non-keratinized stratified epithelium and thickened epithelial segments (plaques) are seen within the lining epithelium. And epithelial lining contains eosinophilic cuboidal type cells, mucous cells and mucin pools in microcystic areas are identified. All cysts were treated by enucleation. All cases are not recurred during follow up period.
2급 치근 이개부 치료 시 합성골 이식 및 혈소판 농축 혈장의 골재생 효과에 대한 디지털 공제술의 정량적 분석
오지수,임성빈,정진형,Oh, Ji-Soo,Lim, Sung-Bin,Chung, Chin-Hyung 대한치주과학회 2001 Journal of Periodontal & Implant Science Vol.31 No.2
The purpose of this study was to evaluate effect of platelet rich plasma on the treatment of Grade II furcation involvement, with and without porous resorbable calcium carbonate($Biocoral^{(R)}$)in humans by digital subtraction radiography. 15 teeth(control group) were treated with porous resorbable calcium carbonate($Biocoral^{\(R)}$), and 15 teeth(test group) were treated with porous resorbable calcium carbonate($Biocoral^{(R)}$) and Platelet Rich Plasma. The change of bone density was assessed by digital subtraction radiography in this study. The change of mineral content by as much as 5%(vol) could be perceived in the subtracted images. The change of mineral content was assessed in the method that two radiographs are put into computer program to be overlapped and the previous image is subtracted by the later one. Both groups were statistically analyzed by Wilcoxon signed Ranks Test and Mann-whitney Test using SPSS program(5% significance level). The results were as follows: 1. In test group, the radiolucency in 3 months after surgry were significantly increased than 1 month after surgery(p<0.05). 2. In test group, there were no significant difference between 1 month after surgery and 6 months after surgery(p>0.05). 3. In test group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 4. In control group, the radiolucency in 3 months and 6 months after surgery were significantly increased than 1 month after surgery(p<0.05). 5. In control group, the radiopacity in 6 months after surgery were significantly increased than 3 months after surgery(p<0.05). 6. There were no significant difference between test group and control group at 1 month, 3 months after surgery, but radiopacity in test group were significantly increased than control group at 6 months after surgery(p<0.05). In conclusion, Platelet Rich Plasma can enhance bone density.
Leigh Syndrome Mimicking Wernicke’s Encephalopathy: A Case Report
오지수,최진옥,김수정,유은애 대한영상의학회 2020 대한영상의학회지 Vol.81 No.6
Leigh syndrome or subacute necrotizing encephalomyelopathy is a rare, rapidly progressive neurodegenerative disorder. In general, symptoms such as shortness of breath and decreased cardiac function usually occur within 1 year of life. It is a serious disease with a mortality rate of 75% in 2–3 years. The cause of Leigh syndrome is DNA mutation. Approximately 75% of patients have nuclear DNA mutations while 25% have mitochondrial DNA mutations. Clinical symptoms vary depending on the affected brain area. Neuroimaging plays an important role in diagnosing patients with Leigh syndrome. Late-onset Leigh syndrome is rarer and progresses more slowly compared to the classic form. Here, we report a case of late-onset Leigh’s syndrome mimicking Wernicke’s encephalopathy.
오지수,심승배,정봉주 대한산업공학회 2010 대한산업공학회 춘계학술대회논문집 Vol.2010 No.6
본 연구는 기업의 변동을 발생시키는 위험에 대해 위험 프레임워크를 구성하고 위험 간 관계와 영향력을 평가하는 위험 네트워크를 개발한다. 개발된 위험 프레임워크를 통해 발생가능한 모든 위험을 포함하고, 위험 네트워크로 영향력과 방향성을 평가한다. 본 연구에서 기업의 변동을 유발하는 것을 위험이라 정의하고, 발생 가능한 위험을 고려한다. 이를 통제여부, 관리수준, 위험 발생 지점을 중심으로 분류하여 위험 프레임워크를 개발해 속성을 부여한다. 이러한 속성을 이용하여 위험을 정량화하고, 각 위험간 영향력과 방향을 측정한 위험흐름을 관리하는 위험 네트워크 모델을 개발한다. 개발된 네트워크는 위험발생노드와 기업의 구성요소노드, 그리고 위험의 이동에 따른 아크로 구성되고 이를 통해 위험탐지 및 노출수준을 결정 가능하다.
Characterization of anti-factor VIII antibody in a patient with acquired hemophilia A
오지수,임영민,장문주,허지영,Midori Shima,오도연 대한혈액학회 2013 Blood Research Vol.48 No.1
Acquired hemophilia A (AHA) is a bleeding disorder caused by the development of an autoantibody against endogenous factor VIII (FVIII). In this study, the epitope of the autoantibody was identified in a 67-year-old female patient with AHA. A prolonged activated partial thromboplastin time (77.4 s) that failed to correct in an incubation mixing test (68.2 s), a decreased FVIII activity, and a high FVIII inhibitor (14.6 Bethesda units/mL) were observed. Enzyme-linked immunosorbent assay demonstrated that the antibody belonged to the immunoglobulin G4 subclass. An immunoblotting assay revealed the light chain (A3/C1/C2 domain) of FVIII as the binding region of the antibody. The bleeding experienced by our patient resulted from the interference of FVIII binding to both FIX by anti-A3 antibodies and phospholipids and von Willebrand factor by anti-C2 antibodies. To the best of our knowledge, this is the first study in Korea characterizing an autoantibody in the context of AHA.
섬유․의류 산업에서의 Quick Response를 위한 지연모델에 관한 연구
오지수,최재형,변태상,정봉주 한국경영과학회 2009 한국경영과학회 학술대회논문집 Vol.2009 No.5
섬유·의류 산업은 제품의 종류가 다양하고 순환주기가 빠르며 고객의 요구 변화가 예측하기 어렵다. 따라서 고객의 수요에 빠르게 대응하는 것이 매우 중요하다. 이를 위해 섬유·의류산업에서는 QR(Quick Response)시스템을 도입하여 고객의 다양한 수요를 충족함과 동시에 생산리드타임과 비용을 최소화하려는 노력을 하고 있다. 이에 본 연구에서는 섬유·의류산업에서 리드타임과 비용을 최소로 하는 지연생산수준(Decoupling Point)을 산출할 수 있는 비용모델을 수립·제안한다. 제안된 비용모델은 섬유·의류산업의 생산관련 비용요소들을 분석하고, 분석된 비용요소들을 Little" Law의 세 가지 생산 시스템 요인들(공정품 재고: WIP, 생산율: TH, 싸이클 타임: CT)로 구성시킨다. 제안된 비용모델은 이론적 검증을 통해 총 비용을 최소로 하는 최적 생산리드타임 즉, 최적지연생산 수준이 존재함을 증명하고, 제품별 최적WIP, CT 등을 제시하도록 한다.