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      • KCI등재

        Capsaicin 약침(藥鍼)이 흰쥐의 급성(急性) 염좌(捻挫)에 마치는 효과

        박상연,최윤영,전인숙,구성태,김경식,손인철,김재효,Park, Sang-Yeon,Choi, Yoon-Young,Jeon, In-Sook,Koo, Sung-Tae,Kim, Kyoung-Sik,Sohn, In-Chul,Kim, Jae-Hyo 경락경혈학회 2006 Korean Journal of Acupuncture Vol.24 No.2

        Objectives: Pharmacopuncture which is a combination of acupuncture and herbal medicine helps to prevent and treat the diseases and symptoms including various pains. However, little was known about the therapeutic effects and its mechanisms on acute pain, although pharmacopuncture has been used frequently in acupuncture clinics. Acupuncture is known for producing analgesia for persistent ankle sprain pain in human. Furthermore, it also produces analgesia in a rat model of ankle sprain pain. Methods: To illuminate the underlying mechanisms of capsaicin pharmacopuncture-induced analgesia, weight bearing force (WBF) was observed on the acute ankle sprained rat model. Ankle sprain was induced in the rat by manually hyper-extending ligaments of the right ankle. Capsaicin pharmacopuncture was applied to SI6 (Yanglo) on the left forelimb (contralateral to the sprained ankle). Results: In behavioral test, capsaicin pharmacopuncture produced marked analgesic effects on acute ankle sprained animals as measured by WBF of the affected limb similar to manual acupuncture. Capsaicin pharmacopuncture was also suppressed by serotonin (5-HT) receptor antagonist methysergide (2 mg/kg, Lp.), but not by opioids receptor antagonist naltrexone (10 mg/kg, Lp.) and alpha adrenoceptor antagonist phentolamine (5 mg/kg, Lp.). Conclusion: The data suggest that capsaicin pharmacopuncture-induced analgesia is accomplished by activating the descending serotonergic inhibitory systems.

      • KCI등재

        Korea's 6th industrial case and competitiveness plan through Japan and China

        박상연,김현준,송덕영,박형호 국제문화기술진흥원 2018 International Journal of Advanced Culture Technolo Vol.6 No.2

        The types of sixth industry to aim of boosting agriculture and rural areas and Korea's sixth industrial cases(Local community, production-centric, distribution-centric, dine out-centric, treatment-centric, exportcentric) and competitiveness measures through Japan and China. Specifically, the competitiveness through the sixth industrial case is to maximize added value through cooperation between communities and to coexist among local residents. Efforts are needed not only to create jobs for the elderly but also to gain consumer confidence, and various measures should be sought to establish a cooperative system. In addition, as customers ' needs change rapidly in the smart age, the life cycle of goods and services is getting extremely faster. Therefore, the sixth industry is expected to be able to predict changes in customer and market trends quickly and accurately, thus making efforts to bring new products and services to market more necessary and contributing to achieving rural activation.

      • KCI등재후보

        Analysis of Actual Consumption Patterns of China's Infant Food Market for 6th Industrial Management System Export Activation

        박상연,송득영,박형호,이남겸,황일영 국제문화기술진흥원 2017 International Journal of Advanced Culture Technolo Vol.5 No.4

        With the increased economic profit in China, people tend to give more attention to the nurturing of children. The change in the food markets directly connected to the infants’ health seem to have brought various consumption patterns different than before. Based on the actual condition survey operated by this research, the expansion in the scale of consumption and preference to the imported food for infants appeared in the Chinese food markets for infants. The rapidly increased amount of the online purchases of the food for Chinese infants was checked through the condition survey. Based on the analysis results, with the purpose of increasing the purchase opportunities of the Korean food for infants to the Chinese consumers, it should not only perform the promotion activities such as the promotion for the product’s superiority and various promotional event, but also establish the pricing strategy for each entry step to the Chinese market. Because the purchase experience of the Korean food for infant plays the important role for the additional payments decision, it is estimated that there is a need to expand the opportunities for the Chinese consumers to approach the Korean food for infants both directly and indirectly.

      • SCOPUSKCI등재

        노인환자에 대한 가족지지와 무력감, 우울과의 관계

        박상연 성인간호학회 1999 성인간호학회지 Vol.11 No.3

        This study was a descriptive correlationstudy. It tried to test the relationships between family support, powerlessness and depression in the elderly patient to develop basic data for nursing intervention. The subjects of this study were 61 patients, over the age of 60, who were admitted in one university hospital in Daegue. The data were analyzed by percentage, ANOVA and Pearson correlation coefficient. The results were as follows : 1. The mean score for family support was 3.52(maximum score : 4). The mean score for powerlessness was 2.51 (maximum score : 4). The mean score for depression was 2.35(maximum score : 4). 2. In general characteristics, educational level and number of children were significantly related to the level of depression 3. The correlations between family support and powerlessness, or family support and depression were negative. The correlation between power- lessness and depression was positive. This study revealed that powerlessness and depression were correlated with family support. Consequently, the implication for nursing is that there is a need to develop an intervention program for the patient's family in order to improve family support.

      • KCI등재

        조산아의 발육성 법랑질 결함의 위험 요인 평가

        박상연,이제호,최형준,강정민 대한소아치과학회 2023 大韓小兒齒科學會誌 Vol.50 No.2

        This study aimed to determine the criteria for quantifying developmental defects of enamel in primary teeth in premature babies and to investigate the severity of developmental defects according to the gestational age, birth weight, systemic complications, and treatments received after preterm birth. Birth information, a history of complications, the duration of parenteral nutrition, and endotracheal intubation were investigated by retrospectively reviewing the admission and discharge records of premature babies in the neonatal intensive care unit. The Preterm Developmental Defects of Enamel (PDDE) index was designed by modifying the existing developmental defects of enamel index. Based on PDDE index, the evaluator scored developmental defects of enamel by classifying them as enamel hypomineralization and hypoplasia. The PDDE scores in the extremely preterm and extremely low birth weight groups were significantly higher than those in other groups. Furthermore, PDDE scores of premature babies with bronchopulmonary dysplasia, rickets, intraventricular hemorrhage, or necrotizing colitis were significantly higher than those in the control group. In addition, more than 50 days of endotracheal intubation and more than 20 days of parenteral nutrition were associated with significantly higher PDDE scores than those in the control group and were risk factors for developmental defects of enamel. This study provides basic information for identifying risk factors for developmental defects of enamel in premature babies. 본 연구는 조산아 유치의 발육성 법랑질 결함을 정량화하는 평가 기준을 제시하고, 조산아의 재태기간, 출생 시 체중, 다양한 합병증 및 치료 이력에 따른 발육성 법랑질 결함의심각도를 조사하고자 하였다. 조산아의 신생아집중치료실 입원 및 퇴원 기록을 후향적으로 평가하여 출생 정보, 합병증 진단 여부, 비경구 영양 및 기관내 삽관 기간을 조사하였다. 기존의 발육성 법랑질 결함 평가지표를 수정하여 Preterm Developmental Defects of Enamel (PDDE) index를 고안하였으며, 평가자는 기준에 맞추어 조산아 유치의 발육성법랑질 결함을 법랑질 저광화와 저형성으로 구분하여 점수화하였다. 재태기간 28주 미만, 출산 시 체중 1000 g 미만인 군의 PDDE score는 유의하게 증가하였다. 기관지폐이형성증, 구루병, 뇌실내출혈, 괴사성 대장염 진단 이력이 있는 군, 기관내 삽관 일수가 50일 이상인군, 비경구영양 일수가 20일 이상인 군 역시 PDDE score를 유의하게 증가시켜 발육성 법랑질 결함의 위험인자임을 확인하였다. 본 연구는 조산아 발육성 법랑질 결함 위험인자를파악하여 조산아의 구강 상태를 예측하고 설명하기 위한 기초 정보를 제공할 수 있을 것이다.

      • KCI등재후보

        두개내압 감압을 위한 Propofol 혼수 치료를 받는 성인 환자에서 발생한 Propofol 정주 증후군

        박상연,김유진,박희평 대한중환자의학회 2013 Acute and Critical Care Vol.28 No.3

        Propofol-related infusion syndrome (PRIS) is a rare but fatal complication. Unexplained metabolic acidosis, rhabdomyolysis, hyperkalemia, myocardial dysfunction, cardiovascular collapse and acute kidney injury are the main characteristics of PRIS. Herein, we report a case of PRIS in a neurosurgical adult patient, who had received high-dose propofol continuous infusion in order to control intracranial pressure in an intensive care unit. She manifested severe metabolic acidosis, rhabdomyolysis, acute kidney injury and myocardial dysfunction. As soon as PRIS was diagnosed, propofol infusion was stopped. Conservative treatments, such as vasopressors and inotropics, continuous renal replacement therapy and extracorporeal membrane oxygenation were used to treat PRIS. However, she finally expired. This case report suggests that a great caution to PRIS is needed in a situation with high-dose propofol continuous infusion.

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