슬관절 전치환술시 경골 결절부 절골술 및 강선 고정술

김택선,윤정로,하권익,심재익,이성종,김영배,김학준,안국환 대한정형외과학회 2003 대한정형외과학회지 Vol.38 No.6

무지외반증에서 근위 갈매기형 절골술 후 고정 방법에 따른 차이: K-강선, 유관나사, 금속판

김택선,김학준,박영환,임형태,Kim, Taik-Seon,Kim, Hak-Jun,Park, Young-Hwan,Lim, Hyung-Tae 대한족부족관절학회 2011 대한족부족관절학회지 Vol.15 No.2

Purpose: The authors evaluated the differences between K-wires and Cannulated screw, plate for fixing the proximal metatarsal chevron osteotomy of moderate and severe hallux valgus. Materials and Methods: There were 62 patients (79 feetz) who were moderate and severe degree hallux valgus according to the classification of Mann. They all got the proximal chevron osteotomy when correcting the deformity. We divided the patients into 4 groups, Two K-wire fixed group as A, one cannulated screw fixed group as B. Two cannulated screw fixed group as C, Plate fixed group as D, Group A were patients (26 feet) and Group B were patients z(9 feet), Group C were patients (31 feet) and Group D were patients (13 feet). Preoperative, postoperative and follow-up hallux valgus angle (HVA) and intermetatarsal angle (IMA) were measured for each patient. ANOVA test and Student t-test were done for statistical analysis. Results: Mean follow up period was 43.8 months (range: 12~82 months). Preoperative mean IMA was $16.4{\pm}3.5$, $17.7{\pm}11.3$, $17.3{\pm}5.9$ and $16.6{\pm}2.3$ degrees in respectively group A, B, C, D. Immediate postoperative mean IMA was $5.6{\pm}3.4$, $7.3{\pm}4.4$, $7.6{\pm}4.4$ and $6.7{\pm}2.8$ degrees in respectively group A, B, C, D. The final mean IMA was $8.9{\pm}4.5$, $15.2{\pm}7.5$, $10.3{\pm}4.4$ and D $7.7{\pm}3.5$ degrees in respectively group A, B, C, D. There were significant statistical increase in final mean IMA of group B and C (p<0.05). Conclusion: The IMA was significantly increased in the group which used one or two cannulated screw for fixation on follow up, therefore more caution should be needed when using one or two cannulated screw fixation technique after proximal chevron osteotomy.

Yersinia enterocolitica O:1,2,3 군과 O:3 군의 균체응집항원과 침강항원의 특이성

김택선,최철순,양용태 중앙대학교 의과대학 의과학연구소 1989 中央醫大誌 Vol.14 No.1

By means of bacterial agglutination, agar gel-diffusion, rocket and two-dimentional immunoelectrophoresis, antigenic relationships of bacterial agglutinogens and precipitinogens between three strains of serogroup 0: 1,2,3 and two strains of serogroup 0:3 of Yersinia enterocolitica were studied. The results were summarized as follows: 1. Crossed bacterial agglutination reactions between strains of 0:1,2,3 and 0:3 to homologous and heterologous rabbit immune sera showed so close relations that strains of two serogroups were not differentiated one another by agglutination test using rabbit anti -0:1, -0:2 and -0:3 sera. 2. Bacterial antigens of 0:1, 2 ,3 cross-reacted with both anti-0:1 serum absorbed with 0:2 and 0:3 groups and anti -0:2 serum absorbed with 0:1 and 0:3 groups, whereas the bacterial antigens of 0:3 group reacted with only absorbed anti-0:1 serum. 3. Out of three bacterial soluble antigens extracted with 0.3% phenol-phosphate buffered saline (PBS), 0.1% Triton X-100-phosphate buffer and 10% trichloroacetic acid solution, the precipitinogen of PBS extract was most highly reactive and stable up to 121˚C for 30 min. The precipitinogen, however, heated at 60˚C for 30 min was more reactive. The heat-stable surface antigen of 0:1,2,3 group was antigenically identical with the antigen of 0:3 group. 4. Fused rocket immunoelectrophoresis revealed that the antigens of 0:1,2,3 and 0:3 groups had one to two common antigens which had a rapider mobility than group specific antigens. 5. By crossed immunoelectrophoresis, the precipitinogens of 0:1,2,3 group had four to five antigens having the relative electrophoretic mobility of 0, 0.15 - 0.18, 0.41, 0.47 -0.5 and 0.58, whereas the precipitinogens of 0:3 group had three antigens having the relative electrophoretic mobility of 0, 0.15 - 0.18 and 0.47 - 0.5. These results indicated that although the strains of 0:1,2,3, group would differ in their subagglutinogens from those of 0:3 group they belonged to 0:3 group by their common 0 group-specific precipitinogens.

하퇴부에 발생한 고립성 퇴행성 신경초종 -증례 보고-

김택선,김학준,김완태,김윤정,윤재은,Kim, Taek-Seon,Kim, Hak-Jun,Kim, Wan-Tae,Kim, Yoon-Jung,Yoon, Jae-Eun 대한근골격종양학회 2006 대한골관절종양학회지 Vol.12 No.1

신경초종이 오래되어서 퇴행성 변화를 일으키면 이를 퇴행성 신경초종이라고 명칭하며, 드물게 보고되고 있다. 혈관주변의 초자화, 출혈, 석회화, 낭성 괴사, Antoni A 구역의 축소, 핵의 변형 등의 퇴행성 변화가 나타날 수 있으며, 이러한 퇴행성 변화로 인해 육종 등으로 잘못 진단되기 쉽다. 본원에서는 75세 남자 환자의 하퇴부에서 광범위한 출혈과 혈종, 낭성 변화, 석회화, Antoni A 구역의 축소 등의 퇴행성 변화가 진행된 퇴행성 신경초종을 경험하였기에 문헌적 고찰과 함께 이를 보고하는 바이다. When the old schwannoma has the degenerative changes, it is named as the ancient schwannoma which was rarely reported. The degenerative changes are perivascular hyalinization, calcification, cystic necrosis, marked decrease of Antoni type A area, and degenerative nuclei and the ancient schwannoma may be misinterpreted as sarcomatous pleomorphisms. We experienced the ancient schwannoma which has massive hemorrhage and hematoma, cystic change, calcification, and marked decrease of Antoni A area in leg on 75 year old male patient, and report it.

Bis-Diazotized Benzidine에 의한 연속 및 동시흡착법에 의하여 Tuberculin PPD로 감작된 적혈구를 이용한 혈구응집반응의 민감성

김택선,정상인,최철순,양용태 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.3

Passive haemagglutination test(PHA) using sheep red blood cells(SRBC) sensitized with soluble antigens by means of coupling agents, i.e., tannic acid, bis-diazotized benzidine(BDB), chromic chloride, glutaraldehyde, and so on, provide an extremely sensitive technique to detect a minute quantity of serum antibody as low as 0.01㎍. It also has advantage over agglutination and precipitation tests in that if it is transferred either to hemolysis test(PHL) or to inhibition test(PHI), soluble antigen-antibody complexes and incomplete or hapten antigen-nonprecipitating antibody complexes that are not detectable by other tests can be demonstrated. This study was undertaken to determine the optimum amount of BDB and tuberculin PPD antigen for consecutive and simultaneous coupling of SRBC in conjunction with the sensitivity of the PHA test. In addition, the sensitivities of PHA and PHL test were compared and the PHA units of antibody and diluents for tuberculin PPD antigen for PHI test were discussed. The results are summarized as follows: 1. The optimum amount of BDB for consecutive and simultaneous coupling of 0.2ml of 2.5% SRBC were 20㎍ and 13㎍, respectively, and the optimum amount of tuberculin PPD antigen were about 125㎍ and 250㎍ respectively. The optimum ratios between BDB and tuberculin PPD antigen for consecutive and simultaneous coupling were 1:6.3 and 1:19.2, respectively. 2. In the consecutive coupling, the PHA titre was linear to both BDB and tuberculin PPD concentrations, whereas in simultaneous coupling it was affected by the level of tuberculin PPD but not by that of BDB from 5㎍ to 13㎍. 3. Using SRBC sensitized consecutively with tuberculin PPD or sensitins prepared from four species of mycobacteria the homologous PHL tests were sensitive than the PHA tests by 1:2 to 1:4 dilutions, and the end-point of PHL test was more clear-cut than that of PHA test.

고령에서 발생한 제1 요추의 호산구 육아종 : 1례 보고 1 Case Report

김택선,이석하,이동기,성낙훈 대한척추외과학회 1999 대한척추외과학회지 Vol.6 No.3

호산구 육아종은 청소년기에 특징적으로 발생사는 양성 종양이다. Histiocytosis의 아분류로 취급 되다가 조직학적 소견이 동일하여 현재는 Langerhans 세포 조직구증으로 불려진다. 골겨계 어디나 침범하지만 두개골에 가장 호발하며, 척추 병소는 10~15%정도이다. Birbeck granules를 세포질내 함유한 Langerhans 세포가 특징적이고 조직구 및 호산구의 증식을 보인다. 저자들은 고령에서 발생한 요추의 호산구 육아종 1예을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Eosinophillic granuloma of bone is a self-limited ondition, characteristically a disease of children and young adults. It is the nost benign variant of histiocytosis X. It is most common in skull, but any bone may be affected. Vertebral involvement occurs in about 10 to 15%. This benign bone destructive lesion is characterized by the presence of Langerhans cells contain Birbeck granules, infilitration of histiocytes and eosinophilic leukocytes unknown origin. We report a eosinophilic ggranuloma in lumbar spine of old patient.

제 14 차 대한골절학회 학술대회 (주연제) : 2. 견봉쇄골관절 분리의 수술적 치료에 대한 임상적 고찰

김택선,심재익,안택근,김종오,임용찬 대한골절학회 1991 대한골절학회 학술대회 및 초록집 Vol.- No.-

Comparison of adhesion and dissolution of fentanyl patches: FentadurⓇ and Durogesic DTransⓇ

김택선,진수언,선보경,김민수,황성주 한국약제학회 2015 Journal of Pharmaceutical Investigation Vol.45 No.5

Fentanyl is a potent opioid used as an analgesic for pain therapy. Fentanyl patches have been developed using patch design technologies that use the transdermal route. The aim of this study was to compare the adhesion and dissolution properties of two fentanyl patches, Fentadur Ⓡ (Pfizer Inc., USA) and Durogesic DTransⓇ (Janssen- Cilag, Inc., USA), which were designed as a reservoir and a matrix, respectively. For the characterization of fentanyl patches, a 180 peel adhesion test and a dissolution test were performed at 12 and 100 lg/h of fentanyl patches. Specifically, the dissolution of fentanyl patches was tested at 32 and 40 ˚C using the USP apparatus 6 and the released fentanyl was analyzed using LC–MS/MS. FentadurⓇ and Durogesic DTransⓇ had acceptable adhesion forces over 150 gf using 12 mm of fentanyl patches. Comparing adhesion forces of FentadurⓇ and Durogesic DTransⓇ, FentadurⓇ had lower adhesion force values than Durogesic DTransⓇ. The release of fentanyl in FentadurⓇ was lower than that in Durogesic DTransⓇ, except for 100 lg/h FentadurⓇ at 40 ˚C over 12–48 h. The results show that FentadurⓇ and Durogesic DTransⓇ had the different properties of adhesion and dissolution, which could be critical factors for the prediction of clinical use.

광류를 이용한 마커리스 증강현실에서의 강인한 카메라 자세추적 알고리즘

김택선,김지훈 제어로봇시스템학회 2013 제어로봇시스템학회 국내학술대회 논문집 Vol.2013 No.5

당뇨병성 족부 질환에 의한 하지 절단 후 임상적 분석과 결과

김택선,강종우,이상준,허영재,김학준,Kim, Taik-Seon,Kang, Jong-Woo,Lee, Sang-Jun,Huh, Young-Jae,Kim, Hak-Jun 대한족부족관절학회 2009 대한족부족관절학회지 Vol.13 No.1

Purpose: The authors evaluated the clinical results and prognosis after amputating the lower extremity due to diabetic foot. Materials and Methods: From 1991 to 2003, the patients who had suffered amputation of his lower extremity due to diabetic foot ulcer were evaluated retrospectively. 79 patients were male and 6 patients were female. The author evaluated the patient who had the ipsilateral additional surgery, contralateral amputation, level of blood sugar, combined disease and mortality rate within 5 years from medical record. Statistical analysis was done by Chi-square test and Kaplan-Meier survival test. Results: Mean age of patients who had first experienced amputation was 63.4 years old. The mean duration of diabetes until amputation was $14.5{\pm}7.5$ years. Major amputations were 50 cases and minor amputations 35 cases. 20 patients (23.5%) were suffered ipsilateral secondary surgery including revised stump. Overall 5-year mortality rate was 18.8% (16 cases). Death rate within 1 year was 8.2% (7 cases), mortality rate within 3 years was 14.1% (12 cases). 5-year mortality rate after major amputation was 20% (10 cases) and after minor amputation was 17.1% (6 cases). It was statistically significant (p<0.05). Patient who underwent more than 2 combined vascular related disease had higher mortality rate than diabetic amputee without combined disease (p<0.05). Conclusion: Mortality rate after major amputation was significant higher than amputation after minor amputation in diabetic patients from our data.