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성인 아토피 피부염 환자의 삶의 질과 중증도에 대한 상관 연구
김남권,이동효,조가원,문효,서은성,Kim, Nam-Kwen,Lee, Dong-Hyo,Jo, Ga-Won,Moon, Hyo,Seo, Eun-Sung 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.3
Objective : The purpose of this clinical research was to analyze the correlation between disease severity and disease specific quality of life adjusted by general quality of life measure in adult patients with atopic dermatitis attending Wonkwang Univ. Sanbon Oriental Medical Center. Methods : A total of 35 patients participated in atopic dermatitis clinical trial from June 1st, 2010 to June 30th, 2011 were included in this study. SCORing Atopic Dermatitis(SCORAD) index, Dermatologic Life Quality Index(DLQI), Health Utility Index III(HUI-III) and EuroQoL 5-Dimension(EQ-5D) have been estimatied. Baseline statistical analysis and normality test were done by using Student t-test, Shapiro-Wilk test and ladder test. Pearson analysis and Spearman analysis were conducted to examined the correlation of each variables. Hierachial regression analysis was performed using related variables. Statistical significance was achieved if the probability was less than 5%. Results : There were statistically significance between DLQI and SCORAD index, and also between DLQI and EQ-5D. However there was no significant between DLQI and HUI-III. In the hierachial regression analysis, after adjusting for demographic variables (gender, age) and general quality of life (EQ-5D), SCORAD index significantly predict the intensity of disease specific quality of life (DLQI). Conclusions : We confirmed the correlation between SCORAD index and DLQI, and developed the inference for regression equation of DLQI using SCORAD index, EQ-5D and demographic variables.
김남권 대한영상의학회 1989 대한영상의학회지 Vol.25 No.6
With the development of software program and special accessory devices affixed to the moving table the technique of multiplanar direct coronal and sagittal CT became available. Multiplanar direct coronal and sagittal images were compared with transaxial images in 70 cases of abdominal and pelvic tumors. The stages were changed in 7 cases and the remainders were shown more exactly cra-niocaudal extensions. As the results these techniques can be more informative to the physician and patients in the preoperative evaluation and the decision of therapeutic plans.
Global existence for 3D Navier-Stokes equations in a long periodic domain
김남권,곽민규 대한수학회 2012 대한수학회지 Vol.49 No.2
We consider the global existence of strong solutions of the 3D incompressible Navier-Stokes equations in a long periodic domain. We show by a simple argument that a strong solution exists globally in time when the initial velocity in H1 and the forcing function in Lp([0; T);L2),T > 0, 2 p +1 satisfy a certain condition. This condition commonly appears for the global existence in thin non-periodic domains. Larger and larger initial data and forcing functions satisfy this condition as the thickness of the domain ϵ tends to zero.
2005년 심사평가원 질의를 근거한 향후 학회의 역할 고찰
김남권,Kim, Nam-Kuon 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3
I reviewed some offical documents from Health Insurance Review Agency(HIRA) asked expert opinions of our society about some controversy between doctors and HIRA The results are as followed : 1. We must compensate the details of textbook about general treatment of frequent1y occurred disease. 2. We mush verify the obstinate disease and write papers consequently. 3. We must educate and use the special techniques of our societic area. 4. We must write papers about the recently developed intervention equipments.
龍膽瀉肝湯의 抗바이러스 活性 및 免疫反應에 對한 實驗的 考察
김남권,김종한,임규상,황충연,Kim, Nam-Kwen,Kim, Jong-han,Lim, Gyu-sang,Hwang, Choong-yeon 대한한방안이비인후피부과학회 1998 한방안이비인후피부과학회지 Vol.11 No.1
During the last few years, nitric oxide(NO) as a potent macrophage-derived effector molecule against a variety of bacteria, parasites, and tumors has received increasing attention. More recent studies suggest that NO also has antiviral effects in both murine and human cells. The objective of the current study was to determine the effect of Yongdamsagantang(YST) on the production of NO. Stimulation of mouse peritoneal macrophages with YST after the treatment of recombinant $interferon-{\gammer}(rlFN-{\gammer})$ resulted in the increased NO synthesis. YST had no effect on NO synthesis by itself. When YST was used in combination with $rIFN-{\gammer}$, there was a marked cooperative induction of NO synthesis in a dose-dependent manner. The optimal effect of YST on NO synthesis was shown 6 hour after treatment with $rIFN-{\gammer}$. This increase in NO synthesis was reflected as increased amount of inducible NO synthase(iNOS) protein. NO production was inhibited by $N^G-monomethyl-L-arginine$. The increased production of NO from $rIFN-{\gammer}$ plus YST-stimulated cells was decreased by the treatment with staurosporin. In addition, synergy between $rIFN-{\gammer}$ and YST was mainly dependent on YST-induced tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ secretion. These results suggest that the capacity of YST to increase NO production from $rIFN-{\alpha}-primed$ mouse peritoneal macrophages is the result of YST-induced $TNF-{\alpha}$ secretion.