The Clinical Usefulness of IgE Antibodies Against Egg White and Its Components in Korean Children

민택기,전유훈,편복양 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.3

Purpose: Egg (egg white) allergies are among the most common food allergies in infants and young children. Serum egg white-specific IgE (sIgE)levels have been shown to be correlated with clinical symptoms, and the predictive decision point of sIgE levels has been proposed and used widelyin the clinical setting. However, some patients whose sIgE levels to egg white are higher than the predictive decision point value show no clinicalsymptoms, and vice versa. This study was conducted to evaluate the clinical usefulness of sIgE antibodies to egg white and its components in thediagnosis of egg allergies. Methods: Forty-one patients younger than 2 years of age with no experience of egg intake due to concerns regardingallergies or a non-specific clinical response to eggs were enrolled. Total IgE levels and the levels of IgE antibodies specific for egg white and its components(ovomucoid, ovalbumin, and conalbumin) were measured by ImmunoCAP testing. The clinical response of the subjects was confirmed by anopen oral food challenge (OFC). Results: Fifteen (71.4%) out of 21 patients in the egg white-sIgE ≥2 kU/L group showed a positive response,while 10 (50.0%) out of 20 patients in the egg white-sIgE <2 kU/L group showed a negative response to the OFC. There were no statistically significantdifferences in the levels of sIgE antibodies against egg white and its components between the positive and negative open OFC groups. In addition,there were no statistically significant differences in the levels of sIgE antibodies against egg white and its components based on an intra-groupanalysis. Conclusions: Our results show that the sensitivity and specificity of the predictive decision point values for egg white-sIgE antibodies byImmunoCAP were relatively low in Korean children. In addition, no egg white component predicted the clinical reactivity of the subjects. We suggestthat the predictive decision point value for a positive egg oral challenge test by ImmunoCAP should be re-evaluated. Moreover, we suggest thatcareful personal history recording and challenge tests are necessary for the correct diagnosis of an egg allergy.

旋盤을 利用한 炭素鋼 麻擦熔接의 機械的 性質에 關한 硏究

閔宅基,남궁척 충남대학교 공업교육연구소 1980 論文集 Vol.3 No.1

In this study, hardness, tensile strength and bending strength of carbon steel in friction welding by use of lathe were observed as follows; 1. The optimum revolution of lathe was found at 1,860 r.p.m. in the fixed conditions of 15kg/cm²of heating pressure, 25kg/cm²of upset pressure and 3.5 seconds of upset time. 2. The hardness of test pieces were increased in weld interface and were decreased in the boundary of 2∼4mm distance from weld interface. 3. Tensile strength and bending strength were increased as compared with original materials.

국내 소아 식품알레르기의 역학

민택기,편복양,김현희,박용민,장광천,김혜영,염혜영,김지현,안강모,이수영,김경원,김윤희,이정민,김우경,송태원,김정희,이용주,전유훈,이소연,대한 소아알레르기 호흡기학회 식품알레르기 아토피피부염 연구회 대한 소아알레르기 호흡기학회 2018 Allergy Asthma & Respiratory Disease Vol.6 No.1

Food allergy has emerged as an important public health problem affecting people of all ages in many countries. The prevalence varies according to age, geographic regions, and ethnicity. For several years, many studies have suggested that the prevalence of food allergy is increasing at an alarming rate, for unclear reasons. Conversely, some studies have also provided findings that sensitization to common food allergens did not increase. Increased recognition rather than an actual increase in patients with IgE-mediated food allergy might lead to the increases in the prevalence of self-reported or physician-diagnosed food allergy. It is also noted that the prevalence of food allergy differs even in the same region according to the study design, i.e., hospital-based or community-based studies. Despite these limitations, epidemiologic data are important because they provide useful information on diagnosis, treatment, and prevention of food allergy. This review focuses on advances in the epidemiology of food allergy in Korean children.

제품개발 프로젝트관리 프로세스 개발

민택기 한국산업경영시스템학회 2010 한국산업경영시스템학회 학술대회 Vol.2010 No.춘계

Regarding project management, many organizations have developed and distributed general project management knowledge systems, and application fields use the knowledge systems to apply the process suitable for characteristics of a project. This study suggests project management process models to apply to product development projects and introduces the application cases. This product development project management process model is composed of five top processes of initiation and preparation, planning, implementation management, control, and termination and transfer. The five processes are re-divided into 18 bottom processes. These processes are expressed as input, control, output, and mechanism by using the IDEF0 model. This model is applied to the new car development project of a Korean automobile company and introduces the cases, which shows a project charter, a work breakdown structure, a project schedule, a progress s-curve, a risk register, and a performance report.

생존 여부에 따른 주산기 가사의 위험요인

민택기,이우령,서은숙 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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議會의 委員會制度와 議事法

閔澤基 全北大學校 法政大學 法政學會 1968 法政學報 Vol.4 No.-

Emerging Therapies in Chronic Spontaneous Urticaria

민택기,Sarbjit S. Saini 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.4

Chronic spontaneous urticaria (CSU) is characterized by typically short-lived and fleeting wheals, angioedema or both, which occur spontaneously and persist for longer than 6 weeks. This term is applied to the most common subtype of chronic urticaria. The underlying pathophysiology for CSU involves mast cell and basophil degranulation with release of histamine, leukotrienes, prostaglandins and other inflammatory mediators. Although a variety of treatments exist, many patients do not tolerate or benefit from the existing therapies and even require more effective treatments. Omalizumab is currently the only licensed biologic for antihistamine-refractory CSU, and novel drugs are under development. This article reviews its current status regarding pathogenesis and approach to treatment as well as therapeutic agents that are under development for the treatment of CSU.

제품개발 프로젝트관리 프로세스 개발

민택기 한국산업경영시스템학회 2010 한국산업경영시스템학회 학술대회 Vol.1 No.-

Regarding project management, many organizations have developed and distributed general project management knowledge systems, and application fields use the knowledge systems to apply the process suitable for characteristics of a project. This study suggests project management process models to apply to product development projects and introduces the application cases. This product development project management process model is composed of five top processes of initiation and preparation, planning, implementation management, control, and termination and transfer. The five processes are re-divided into 18 bottom processes. These processes are expressed as input, control, output, and mechanism by using the IDEF0 model. This model is applied to the new car development project of a Korean automobile company and introduces the cases, which shows a project charter, a work breakdown structure, a project schedule, a progress s-curve, a risk register, and a performance report.

조기이유와 자돈의 대용유

민택기,Min, Taek-Gi 대한양돈협회 1990 養豚 Vol.12 No.2

STS304와 6000계열 알루미늄 합금의 마찰용접성

강성보,윤병수,홍일표,민택기 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1

This study deals with the friction weldability of STS304 Austenitic stainless steel to 6000 series aluminium alloys, those are A6061-T6, A6063, A6351. The total upset the biggest in case of STS304-A6063 and depend on strength of aluminium alloy. All welded specimen in the condition of upset pressure 75MPa exceeded the tensile strength of base metal. As a result of analyzing the tensile fracture surfaces, it showed ductility in case of both STS304-A6063 and STS304-A6351, while it showed poor ductility in case of STS304-A6061-T6. The results of bending test coincide with characteristic of tensile fracture surfaces. In the case of STS304-A6063 and STS304-A6351, any crack did not appear in welded joint, even in bending up to 90o. As a result of EDAX analysis of welded joint, it has been confirmed that Ni, Cr and Fe in STS304 were diffused toward aluminium alloy side. Consequently, friction weldability of STS304-aluminium alloys is determineded by combination of micro deformation and diffusion.