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안구적출에 따른 위둔덕의 칼슘결합단백질의 재구축 및 상호 연관성
안병수,고길석,안명수,김경주,권안성,정명섭,박춘매,조병옥,김진우,Samudra Acharya,Parmeshwar Narayan Amatya,장인엽 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1
Background: Superior colliculus is a part of midbrain, and participates in the visual reflexes, It receives afferent fibers from optic nerve, visual cortex, and spinotectal tract. After optic deprivation, the microscopic structure of the superior colliculus changed. Calcium-binding proteins (CBPs) Play an important role in the neuronal protection, differentiation and reorganization of the central nervous system, Objectives and Methods: The effects of neonatal retinal deafferentation on a CBPs, calbindm D-28k (CB), Parvalbumin (PB) and calretimn (CR), and the existence of colocalization between the CBPs were examined immunohistochemically in the rat superior colliculus. Results: On the experimental (contralateral to enucleation) side of superior colliculus, the number of CB-immunoreactive (IR) cells was reduced (77.4% compared to control), but not fibers. The number of PB-IR neurons and fibers was also reduced on the experimental side (88.5% compared to control), In the other hand, the CR-IR cells were dramatically increased (642% compared to control), but CR-IR fibers were markedly decreased on the experimental side. The colocalization between CB-CR and PV-CR was rarely observed in the superior colliculus Conclusion: These results suggest that the changes of retinotectal projection may alter the expressional pattern of CBPs in different manners; relatively stable in CB- and PV-IR neurons and plastic in CR-IR neurons.
IMPROVED ALGORITHM BASED ON AEKF FOR STATE OF CHARGE ESTIMATION OF LITHIUM-ION BATTERY
Yu-Zhen Jin,Chenglong Su,Shichang Luo 한국자동차공학회 2022 International journal of automotive technology Vol.23 No.4
State of charge (SOC) is one of the most significant parameters in the battery management system (BMS). Accurate estimate of the SOC can prevent the battery overcharge and over-discharge, which can effectively increase the life of the Lithium-ion battery and improve the safety of electric vehicle. In this paper, an improved second-order equivalent model is established. The improved model distinguishes the direction of charge and discharge for the resistance and capacitance parameters. To improve the estimation accuracy of SOC, this paper proposes an improved Adaptive Extended Kalman Filter by introducing an iterative method into the AEKF algorithm. The improved algorithm mainly uses the measured voltage data to adjust the covariance matrix P multiple times in one calculation step to reduce the error in the linearization process. The dynamic stress test (DST) and urban dynamometer driving schedule (UDDS) are applied to verify the validity and accuracy of the improved algorithm. The experimental results show that the algorithm proposed in this paper has faster convergence and more accurate compared with AEKF algorithms.
Effect of Sub-Structure and Precipitation Behavior on Mechanical Properties of Al–xCu–Li Alloys
Yu‑zhuo Li,Guang‑jun Zeng,Ding‑ding Lu,Zhen‑zhen Liu,San‑xi Deng,Peng‑cheng Ma,Yong‑lai Chen,Rui‑feng Zhang,Jin‑feng Li 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.11
The tensile properties and microstructure of extruded and cold rolled 2A55 Al–Li alloys with different Cu content werestudied. After solution treatment, the strength of extruded sheets is slightly higher than that of cold rolled sheets due to strongdeformation texture and high density of substructure. However, the strength change order is different with the increase of Cucontent with T6-24 h. The extruded sample with higher Cu content have higher strength due to many dense T1precipitates. The δ′/θ′/δ′ composite precipitates and θ′ precipitates suppress the formation of T1precipitates, which cause cold rolled samplewith higher Cu content shows lower strength. Additionally, many fine T1precipitates nucleate at the sub-grain boundariesformed in the extrusion process, which have a significant effect on the mechanical property.
Morphological Variation of Cultivated and Weedy Types in Perilla Crop Collected from South Korea
Zhen Yu Fu,사규진,이수경,이주경 한국약용작물학회 2023 한국약용작물학회지 Vol.31 No.1
Background: Perilla (Perilla frutescens L.) has been widely cultivated and used for medicinal use, aromatic, functional food, and ornamental plant in South Korea. To understand the morphological variation in the cultivated and weedy types of Perilla (CWTP) collected from South Korea, 52 accessions collected from different areas were evlauated using one quantitative and 10 qualitative characteristics. Methods and Results: Principal component analysis (PCA) was performed using the NTSYS-pc V2.1 program to detect the differences among the accessions of the CWTP. Multivariate analysis was performed using Microsoft Excel Statistical Analysis System. The cultivated P. frutescens var. frutescens and two weedy types of Perilla crop were accurately distinguished based on he 11 morphological characteristics, paricularly seed related traits, used in the study. PCA results showed that, most morphological characteristics such as weight per 100 seeds (QN1), color of leaf adaxial side (QL1), color of leaf abaxial side (QL2), stem color (QL4), flower color (QL5), seed size (QL9), and seed hardness (QL10) provided a significant contribution in the positive or negative direction on the first axis. These characteristics are considered useful for distinguishing between accessions of the CWTP collected from South Korea. Conclusions: The accessions of weedy P. frutescens var. frutescens are located between the accessions of cultivated P. frutescens var. frutescens and the those of weedy P. frutescens var. crispa on the first axis. Although the cultivated and weedy types of P. frutescens var. frutescens and the two weedy types of P. frutescens var. frutescens and P. frutescens var. crispa cannot be completely distinguished, the results provide useful information for future studies on the identification and classification of CWTP germplasm accessions collected from different areas in South Korea
Yu-Xiang Yang,Zhen-Hua Xu,Yu-Qian Zhang,Jing Tian,Li-Xing Weng,Lian-Hui Wang 한국미생물학회 2012 The journal of microbiology Vol.50 No.6
Quorum sensing (QS) has been a novel target for the treatment of infectious diseases. Here structural analogs of Pseudomonas aeruginosa autoinducer N-acyl homoserine lactone (AHL) were investigated for QS inhibitor (QSI) activity and a novel QSI was discovered, N-decanoyl-L-homoserine benzyl ester (C2). Virulence assays showed that C2 downregulated total protease and elastase activities, as well as the production of rhamnolipid, that are controlled by QS in P.aeruginosa wild-type strain PAO1 without affecting growth. C2 was also shown to inhibit swarming motility of PAO1. Using a microdilution checkerboard method, we identified synergistic interactions between C2 and several antibiotics, tobramycin, gentamycin, cefepime, and meropenem. Data from real-time RT-PCR suggested that C2 inhibited the expression of lasR (29.67%), lasI (21.57%), rhlR (28.20%), and rhlI (29.03%).
Zhen-Yu Wu,이영주,신영일,최수정,백수연,천정환,Loai Saleh Albinsaad,최우정,김남국,고범석 한국유방암학회 2021 Journal of breast cancer Vol.24 No.3
Tumor localization is challenging in the context of ductal carcinoma in situ (DCIS) treated with breast-conserving surgery. Conventional localization methods are generally performed under the guidance of ultrasonography or mammography and are rarely performed with magnetic resonance imaging (MRI), which is more sensitive than the aforementioned modalities in detecting DCIS. Here, we report the application of MRI-based individualized 3-dimensional (3D)-printed breast surgical guides (BSGs) for patients with breast cancer. We successfully resected indeterminate and suspicious lesions that were only detected using preoperative MRI, and the final histopathologic results confirmed DCIS with clear resection margins. MRI guidance combined with 3D-printed BSGs can be used for DCIS localization, especially for lesions easily detectable using MRI only.