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      • 위암 환자에서 위절제술후 나타나는 담도확장의 임상적 의의: 추적 CT 소견을 중심으로

        윤구섭,백승연,이문규,김영환,오용호 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.1

        A retrospective review of consecutive 35 patients'pre and post operative abdominal computed tomography was performed to determine frequency and degree of bile duct dilatation following Billroth Ⅱ operation for stomach cancer and it's clinical significance. Degree of intrahepatic biliary dilatation was classified as mild, moderate, marked according to the extension into central, middle and peripheral zone of liver, respectively. Three specialists on the abdominal image participated in analysis of those findings without prior information of the patients. Intrahepatic biliary dilatation was seen in 22 patients(63%) analysed by at least one radiologist, in 13 patients(37%) by at least two radiologists. Bile duct dilatation on CT was common finding and not necessarily meant tumor recurrence. Vagotomy and afferent loop resulted form Billroth Ⅱ were one of possible causes of bile duct dilatation. This study showed in the cases of bile duct dilatation without clinical and other radiological evidence of recurrence, no further study are needed and only enough to follow up study.

      • 급성골수백혈병에 대한 관해유도화학요법 후의 Granulocyte Colony-stimulating Factor의 효과

        윤환중,최지영,전의건,길준영,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Granulocyte colony-stimulating factor(G-CSF) have been shown to hasten the recovery of neutropenia following anti-cancer chemotherapy. There are controversial opinions on the use of G-CSF in acute myelogenous leukemia(AML) because clonogenic studies have shown that G-CSF stimulates leukemic colonies as well as granulocyte colonies. In this study, we evaluated the effectiveness and safety of recombinant human G-CSF after induction chemotherapy with DAV regimen(Ara-C 100mg/㎡ day 1-8, Doxorubicin 45mg/㎡ day 3-5, VP-16 100mg/㎡ day 6-8) in 9 patients with AML. G-CSF therapy(200 ㎍/㎡/day) was begun 2 days after the end of chemotherapy and continued for 10 days. 17 AML patients who recieved the same chemotherapy before the onset of this study were used as historical control. G-CSF shortened the duration of granulocytopenia (less than 500/㎣) significantly (13 vs 23 days, p<0.001), but it had no effect on platelet recovery. Although the incidence of febrile episodes was almost the same, the duration of febrile episodes was shorter in the group treated with G-CSF( 5 vs 12 days, p=0.03). There was no evidence that G-CSF accelerated the regrowth of leukemic cells and the complete remission rates between the 2 groups were not different. These results show that G-CSF accelerates the recovery of granulocytopenia and shortens the febrile days after chemotherpy in patients with AML, without affecting the regrowth of leukemic cells.

      • SCOPUSKCI등재

        몇가지 植物의 棲息地 造成에 關한 硏究

        윤종선,김익환,신세균,심우경,이철희,신영철 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.2

        종의 棲息密度가 낮아지고 있는 하늘나리, 섬초롱, 자란 3종의 식물을 인위적으로 棲息地를 造成하기 위하여 국립공원 속리산 등산로변 標高 200m, 400m, 600m 지점에 150주식 종당 450주를 조직배양 및 분주에 의하여 육묘 된 묘를 이식하여 생존상태 및 棲息地 造成의 가능성을 2년에 걸쳐 검토한 결과는 다음과 같다. 1. 造成 棲息地의 토양의 理化學的 造成은 pH 5.2∼5.6, 유기물 함량 29∼54g/㎏, CEC 9.4∼11.5㎝ mol(+)/㎏으로 산성을 띠고 있었으며, 유기물 함량은 높은 편이었고, 염기치환용량은 낮았으나 비교적 우리나라 典型的 山地土壤의 理化學的 造成과 유사하였다. 2. 棲息地內 생장기간의 投光率은 標高 200m 지역은 10.8∼11.6%, 400m lw역은 10.8∼11.4%, 600m 지역은 11.0∼12.8%로 식재식물의 生長環境에 부족한 상태였다. 3. 식재 식물 수는 식재 후 활착율은 3종 모두 양호하였으나, 점차 감소되었으며, 특히 자란의 감소율이 높았다. 감소의 원인을 분석한 결과 하늘나리, 섬초롱, 자란 모두 굴취나 절취의 피해가 많았으며, 특히 자란은 凍害에 의한 枯死가 1년차 72∼86주, 2년 차에서 19∼35주로 조사도어 자연상태에서의 越冬은 어려운 것으로 나타났으며, 집중호우에 의한 流失도 감소의 한 원인이었다. 4. 식재식물의 생장상태는 불량하였는데 이는 投光量 부족으로 판단되어 棲息地造成時에는 錄陰期 投光量에 대한 사전 검토가 중요한 요인으로 나타났다. 5. 개화율은 섬초롱과 자란에서 높았으며 標高가 높을수록 개화기는 2∼4일 늦어지고 휴면기는 빨라지는 경향이었다. 식물 棲息地 造成時에는 造成 식물의 생장에 적합한 토양, 光環境 등을 고려한 위치 선정이 중요하며, 上層林에 의한 遮光으로 下層 초본식물 遷移速度가 빨라짐으로써 光環境 개선을 위한 上層林의 間伐, 周邊樹種의 更新이 요구된다. In order to make the artificial habitats of Lillium concolor, Campanula takesimana and Bletilla striata that the number of plant became sparse, 150 plants per species were transplanted at the region of 200m, 400m and 600m above sea level. And the growth of plants and the potential as habitats creation were analyzed. In the physical and chemical properties of soils in the there, soil pH was 5.2 to 5.6, organic matter content was 29 to 54g/㎏ and cation exchange capacity(CEC) was 9.4 to 11.5㎝ mol(+)/㎏. The transmittance rates of sunlight of the habitats during the growing periods were 10.8 to 11.6% in the 200m region, 10.8 to 11.4% in the 400m region and 11.0 to 12.8% in the 600m region. These transmittance rates were deficient for normal growth of plants. After the plants were transplanted, the survival rates of three species were high in common but the rates decreased gradually. Especially the decrease rate was high in the Bletilla striata. The causes of decrease were digging and cutting by climbers, sweeping asay by rainfall and freezing damage. Especially, the cold tolerance of Bletilla striata was weak in the natural condition. The growth of planted plants was poor, and it was assumed that the reason was shortage of sunlight transmittance. The flowering rates were high in the Campanula takesimana and Bletilla striata. And as the elevations were high, the flowering was later by 2 to 5 days but the dormancy was earlier. In the artificial making of plant habitats, the growth environment of plants have to be considered to choose the suitable region. And, because the habitats are shaded by the trees and bushes, the thinning of trees and the change of species are needs to improve the light transmission.

      • 로봇 그립퍼의 악력 제어

        윤동우,오성남,김갑일,손영익,임승철,강환일 明知大學校 産業技術硏究所 2007 産業技術硏究所論文集 Vol.26 No.-

        In addition to accurate position and velocity control, force control is necessary for a successful robot operation. In this paper, we have designed a simple robot gripper using a DC motor. For its force control, a current feedback control law is presented without using additional force sensors. Experimental results prove the effectiveness of the proposed control law. A digital controller is also developed with a TMS320LF2406 processor.

      • MOS 構造에서 Annealing 處理가 酸化膜내의 電子 Trapping現象에 미치는 影響

        尹榮均,李憲用,朴寅煥 明知大學校 産業技術硏究所 1991 産業技術硏究所論文集 Vol.10 No.-

        As the thickness of thermally grown oxide films becomes thinner, the electric fields at the gate oxide films are increased and hot electrons are generated which affect the stability of devices. In this paper, we consider the effects on the charges in the oxide and Si-iO₂ interface by postoxide and postmetal annealing processes and the trun around effects compensating negative charges by growth of positive charges when avalanche electron trapping is generated in the oxide films of MOS structures.

      • FCL(5-FU, Carboplatin, Leucovorin) 항암 화학요법에서 Gm-CSF의 효과

        최지영,김현수,김종숙,박상준,윤환중,조덕연,남상륜,김삼용 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

        Background: One of the major side effects of cancer chemotherapy is myelosuppression. Neutropenia and/or thrombocytopenia are dose-limiting factors in chemotherapy. Colony-stimulating factor induces proliferation and functional maturation of hematopoietic progenitor cells. GM-CSF is primarily active on progenitor cells of granulocytic and monocytic lineage. Methods: Fifteen patients with histologically proven malignancy diagnosed at Chungnam National University Hospital from January 1993 to August 1995 were included in this study. We could evaluate the clinical efficacy of GM-CSF in 13 patients undergoing FCL(5-FU, Carboplatin and Leucovorin) chemotherapy; the first cycles involved no GM-CSF while the second cycles involved GM-CSF on day 6 through 15 of chemotherapy. Results: 1) The subjects were fifteen patients in all, there were five patients with head and neck cancer, which was the most common types of maligancy. There were four patients with colon cancer, two patients with stomach cancer, and one patient with breast cancer, gallbladder cancer, cervix cancer and cholangiocarcinoma respectively, two patients, who did not complete two cycles of chemotherapy were excluded. 2) Age distribution was from 38 years to 78 years with a median age of 57. 3) In FCL chemotherapy cycles with GM-CSF, the duration of neutropenia(<500/μL) was 0.5±0.3 day, while FCL chemotherapy cycles without GM-CSF, it was 2.9±0.7 day(P=0.008). 3) There was no significant difference in platelet count between the two chemotherapy cycles(P=0.133). 4) Febrile duration without GM-CSF was 4.9±2.1 day, but with GM-CSF the duration was 1.3±0.7 day, which was significantly different(P=0.003). The duration of antibiotics use with GM-CSF was 1.7±1.2 day and without GM-CSF was 6.8±3.2 day, also significantly different(P=0.002). But hospital stay between the two cycles were not significantly different(P=0.064). Conclusion: GM-CSF was effective in preventing or restoring bone marrow depression after FCL chemotherapy.

      • KCI등재

        최적 금형연마 가공을 위한 센서 정보 통합 전문가 시스템 개발

        안중환,김화영,申云峰,정해도,조규갑 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.1

        This paper presents a polishing expert system integrated with sensor information which can modify the polishing sequence and conditions initially determined by the system depending on the on-site polishing status. A practical system using AE sensor to detect the on-line polishing status is developed for the rotational polishing and the smoothly curved sur-face. Database and knowledge base for polishing processes are established by using the results of experiments and also expert's experience. Evaluations are performed for a die of headlight lamp by using both the sensor integrated expert sys-tem and the expert system without sensor. The test results show that the sensor integrated expert system provides more optimal polishing conditions since the proposed system takes advantage of the on-line sensor information.

      • 입원한 정신분열병 환자의 종합 검사 중 로샤 검사의 대응 손상 지표(Coping Deficit Index) 수준과 다른 검사들 간의 관계 연구

        최윤희,김재환,이영호 가톨릭대학교 사회과학연구소 2005 社會科學硏究 Vol.21 No.-

        본 연구는 정신분열병 집단 내에서 로샤 검사의 대응 손상 지표 수준과 다른 검사들의 수행 간의 관계를 통해 한 검사에서 보이는 지표가 다른 검사에서 어떻게 나타나는지 확인하고자 하였다. 정신과 입원 환자 중 정신분열병으로 진단된 환자들을 로샤 검사의 대응 손상 지표 수준에 따라 집단1(CD1=<3)과 집단2(CDI>3)와 같이 두 집단으로 나누었다. 이들을 대상으로 K-WAIS, MMPI, SCL-90-R 검사와 같이 객관적 채점 및 해석이 가능한 변인을 고찰하였다. 연구 결과, K-WAIS 검사의 상식 소검사, 어휘 소검사, 이해 소검사, 공통성 소검사, 언어성 지능 및 전체 지능에서 두 집단 간에 유의미한 차이를 보였다. 그러나 이를 제외한 K-WAIS의 나머지 소검사들과 동작성 지능에서는 차이가 유의미하지 않았으며, MMPI와 SCL-90-R 검사의 소척도들에서도 집단 간에 유의미한 차이가 나타나지 않았다. 끝으로 본 연구의 제한점 및 향후 연구 방향이 논의되었다. The purpose of this study was to explore how the signs of a psychological test could be manifested in the other test. The subjects groups consisted of following: group 1(CDI=<3), group 2(CDI>3). The results are as follows: First, the group 1 showed greater performance than group 2 in the K-WAIS subtests as information, vocabulary, comprehension, similarities, verbal intelligence quotient and full scale intelligence quotient. But there was no significant results on the other subtests. Second, there were no significant differences in the subtests of the MMPI nor the SCL-90-R between the group 1 and group 2. In conclusion, research implications, limitations of the study and suggestions for future studies were discussed.

      • 純 알루미늄의 旋削特性

        李允景,崔榮煥 慶南大學校 附設 工業技術硏究所 1986 硏究論文集 Vol.4 No.-

        本 實驗에서 純 알루미늄을 族削材로 하고 超破合金工具 SNMA332 및 SNMG332를 使用하였을 때 低速에서 高速으로 多樣한 變化에 대하여 族削의 諸特性을 實驗하였다. In present investigation, all characteristics in turning of pure aluminium with sintered carbide tool, SNMA332 and SNMG332, were carried out in various cutting speed varying from low speed to high speed.

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