유아 로타바이러스 설사증에 대한 IgY 난황 항체의 효과시험

정동혁, 박효선, 김경미, 정규항, 김강영, 정후길, 윤숭섭, 전호남, 강신영 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

위의 유암종과 선종의 병발 1례

장재식,강혁주,이중현,서영범,윤병구,김용섭,이구,서정일,양창헌,이창우,김정란,윤환중 東國大學校醫學硏究所 2000 東國醫學 Vol.7 No.-

유암종은 전신에 퍼져 잇는 장크롬친화성 세포에서 기원하는데 위의 유암종은 비교적 드문 질환으로 모든 유암종의 1.9~2.2%에 해당하며 위에 발생하는 종양의 1% 미만에서 보고되고 있다. 유암종은 일반적으로 증상이 비특이적이고 면역조직화학검사에 의해서 진단되기 때문에 과거에는 드물게 발견되었으나 최근 내시경 기기 및 술기의 발전과 검사 빈도의 증가 및 면역조직화학검사의 발달로 진단율이 증가 추세에 있으며, 드물지만 유암종에서 선암과 공존하는 예들이 보고되고 있다. 저자들은 심와부 동통을 주소로 내원한 70세 남자 환자의 상부위장관내시경 검사에서 위체상부의 대만곡에서 0.4×0.4 cm 크기의 중간 함몰을 가진 Yamada 1형의 용종과 함께 전정부의 전벽에서 0.8×0.5 cm 크기의 융기된 점막 소견을 보여 조직학적으로 각각 위유암종 및 위선종임을 확진한 후 내시경적 용종 절제술로 치료한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Carcinoid tumors are arisen from enterochromaffin cells, which are scattered throughout the body. These tumors are composed of variable numbers of cells that contain endocrine granules in their cytoplasm, which can be identified by immunohistochemistry and electron microscopy. Gastric carcinoid tumors are relatively rare tumor, the reported incidence being 1.9~2.2% of all carcinoid tumors and less than 1% of all gastric tumors. Sometimes, composite carcinoid tumors and adenocarcinoma is reported. We experienced a case of the coincidence of carcinoid tumor and adenoma at the other site of the stomach in a 70 year old male patient. Gastrofiberscope showed 0.4×0.4 cm sized Yamada type I polyp with central depression on the greater curvature of the proximal body and 0.8×0.5 cm sized focal slightly elevated mucosa on the anterior wall of the antrum. The endoscopic biopsy specimens revealed carcinoid tumor and tubular adenoma with moderate atypism, respectively. The carcinoid tumor and adenoma were removed by endoscopic polypectomy. According to the follow-up gastrofiberoscopy after 7 month later, both lesions were nearly normal mucosa except whitish atrophic change after polypectomy.

전문비서직에 대한 이대 비서학과 학부학생들의 의식구

구효선,김경화,윤혜정,이지연,정은희,강은정,김윤희,신해정 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

논문 : Top-Down 공법이 적용된 흙막이벽의 역해석을 이용한 거동분석

홍원표 ( Won Pyo Hong ),강철중 ( Chul Joong Kang ),윤중만 ( Jung Mann Yun ) 대한지질공학회 2012 지질공학 Vol.22 No.1

본 연구에서는 흙막이벽 설계시 널리 사용되고 있는 SUNEX 프로그램을 이용하여 Top-Down 공법이 적용된 지중연 속벽, 주열식 흙막이벽 (CIP벽, SCW벽)의 변형거동을 분석하였다. 해석프로그램에 Rankine의 토압(l857), Terzaghi and Peck의 토압(1967), Tschebotarioff의 토압(1973), 홍원표·윤중만의 토압(1995a)을 적용하여 흙막이벽의 수평변위를 예측하였다. 프로그램 해석결과, 흙막이벽의 수평변위량은 토압의 종류에 따라 큰 차이를 나타내고 있다. 홍원표·윤중만의 토압(I995a)을 적용하여 얻은 흙막이벽의 예측수평변위량이 실측수평변위량과 가장 유사하게 나타났다. 따라서 프로 그램 해석시 홍원표·윤중만의 경험토압(l995a)을 적용하면, Top-Down 공법이 적용된 흙막이벽의 변형거동을 비교적 정확히 예측할 수 있다. Abstract: The behaviors of a diaphragm wall and a contiguous pile wall such as CIP (Case-in-place pile) and SCW (Soil-cement wall), applied to the top-down construction method, were analyzed using the SUNEX program, which is widely used to design earth retaining walls. Four types of earth pressures, as described by Rankine (1857), Terzaghi and Peck (1967), Tchbotarioff (1973), and Hong and Yun (1995a), were applied to the analysis program to predict the lateral displacement of walls, The results show that the displacements of an earth retaining walls vary with the applied earth pressure. The predicted lateral displacement based on Hong & Yun`s (1995a) earth pressure is similar to the measured displacement. Therefore, the actual lateral displacement of an earth retaining wall, as applied to top-down construction method, can be accurately predicted by using an analysis program considering Hong and Yun`s (1995a) earth pressure.

Top-Down 공법이 적용된 지중연속벽의 설계시 측방토압의 적합성 평가

홍원표(Hong Won-Pyo),강철중(Kang Chul-Joong),윤중만(Yun Jung-Mann) 한국토목섬유학회 2012 한국지반신소재학회 논문집 Vol.11 No.1

본 연구에서는 지중연속벽 설계시 사용되는 범용 해석프로그램에 Rankin(1857)의 이론토압과 홍원표와 윤중만(1995a)의 경험 토압을 각각 적용하여 Top-Down 공법에 적용된 지중연속벽의 수평변위를 분석하였다. 그리고 이들 해석 프로그램에서 산정된 예측변위량과 지중경사계로 측정된 실측변위량을 비교 검토하였다. 현재 지중연속벽 설계에 적용되는 해석프로그램에는 Rankine의 토압이 주로 적용되고 있다. 검토결과, 지중연속벽의 예측수평변위는 적용되는 토압에 따라 상당히 큰 차이를 나타내고 있다. Rankine의 토압을 적용하여 산정된 예측수평변위 형상은 실측결과와 큰 차이를 보이고 있으며 벽체의 하부에서 예측치가 실측치보다 과다하게 산정되었다. 반면, 홍원표·윤중만의 토압을 적용하여 얻은 예측수평변위 형상과 최대수평변위 량은 실측결과와 유사하게 나타났다. 따라서 Top-Down 공법이 적용된 지중연속벽의 설계시 Rankine의 토압보다는 홍원표·윤중만의 경험토압을 적용하는 것이 적합함을 알 수 있다. The Rankine(1857)'s earth pressure and the Hong and Yun(1995a)'s earth pressure was applied to analyze the lateral displacement of diaphragm wall applied to the Top-Down construction method using the computer program, which is a common design program for diaphragm wall. The lateral displacement estimated by the computer program was compared with the lateral displacement measured by inclinometer. The Rankine's earth pressure has been widely used to design the diaphragm wall in the analysis of computer program. As the result of comparison, the lateral displacement of diaphragm wall was predicted differently according to the applied earth pressures. The behavior of lateral displacement predicted by the Rankine's earth pressure was different with displacement measured by inclinometer and the lateral displacement at the bottom part was overestimated. However, the lateral displacement predicted by the Hong and Yun's earth pressure is similar to the behavior and maximum value of real displacement. Therefore, the Hong and Yun's earth pressure is more suitable than the Rankine' earth pressure to design the diaphragm walls applied to the Top-Down Construction Method.

6-(3,4-디클로로페닐)아미노-7-클로로-5,8-퀴놀린디온의 항진균작용 및 안전성 평가

윤여표,김동현,이병무,허문영,정해문,강혜영,최정아,김도희,유충규 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

6-(3.4-Dichlorophenyl)amino-7-chloro-5.8-quinolinedione (RCK50) was tested for antifungal activities in mice systemically infected with Candida albicans. The therapeutic potential of RCK50 was also assessed in comparison with ketoconazole. RCK50 had ED_50 0.22±0.01 ㎎/㎏. Ketoconazole as a positive control had ED_50 6.00±1.70 ㎎/㎏. Intraperitoneally administered RCK50 at the ED_50 for 7 days and 14 days reduced Candida albicans colony count in the kidneys and liver. And administered RCK50 at the ED_50 for 14 days improved survival rates. The genotoxicities of RCK50 had been evaluated. RCK50 was negative in Ames test with Salmonella typhimurium and chromosomal aberration test in CHL cells. RCK50 did not show any clastogenic effect in mouse peripheral blood and was negative in mouse micronucleus assay. These results indicate that RCK50 has no genotoxic potential under these experimental conditions. Acute oral toxicity studies of RCK50 were carried out in ICR mice of both sexes. RCK50 did not show acute oral toxicities and LD_50 values were over 2.850 ㎎/㎏ in ICR mice.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

중독한 추체로 증상을 보인 cyclosporine에 의한 뇌증 1예

강정현,곽승근,신현영,김성은,이정호,이정찬,곽상혁,윤환중,조덕연,김삼용,김제,송창준 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

The use of cyclosporine(CsA), a potent immunosuppressive agent, is associated with numerous side effects. Neurotoxicity was earlier less well known, but with growing experience central nervous system side effects are now reported up to 40% of patients. Among various CsA-induced neurotoxicities, tremor is most common and posterior leukoencephalopathy is well characterized. An encephalopathy presenting with pyramidal weakness, however, seems to be rare and poorly documented. We report here a case of encephalopathy presenting with multiple generalized seizures followed by fluctuating quadriparesis developed a few days after starting CsA and resolved spontaneously after withdrawal of the drug . A 48-year-old woman with aplastic anemia was placed upon immmunosuppressive treatment consisting of antithymocyte globulin(ATG), CsA, and methylprednisolone. Two days after starting the therapy, she developed a generalized seizure. The next day she developed 2 more episodes of seizure and the therapy was stopped. Computed tomogram of the brain was normal. Six days after starting therapy, she developed mild motor weakness and paresthesia of both lower extremities, which progressed to a definite quariparesis confining her to a bed in 3 days. Magnetic resonance imaging(MRI) of the brain revealed asymmetric, bilateral high-signal abnormalites in the subcortical white matter of fronto-temporal areas. After reaching to a maximum with some fluactuation(14 days after starting the therapy) the motor weakness started to be resolved. She was discharged with a almost complete resolution of the weakness 45 days after starting the therapy. Five months later she did well and brain MRI was negative.

法醫剖檢과 誤診 : 1990년 국립과학수사연구소 부검예를 중심으로

尹重鎭,姜信夢 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Misdiagnosis is frequently confronted in clinical medicine as a cause of medical dispute. However, misdiagnosis itself is not medical malpractice. The decision of medical error or fault has to be performed through careful investigation about violation of due care. There were 54 cases of misdiagnosis, clarified by medicolegal autopsy in National Institute of Scientific Investigation at 1990, among 118 deaths associated with medical part (internal medicine and pediatrics) occupied 57.4%, and surical part (surgery and ObGy), 31.5%, and remaining minor parts, 11.1%. The rate of misdiagnosis were more remarkable in medical part than surgical part. It showed characteristic differences between medical and surgical cases in subtypes of misdiagnosis. Wrong and under diagnosis were main subtypes in medical cases and skipped diagnosis in surgical cases. Unfortunately, this report does not include comments on error of the cases due to shortage of materials. but the status and patterns of misdiagnosis could be appreciated through this report.

대학생의 사회도덕적 경험과 도덕성 발달

강윤정 德成女子大學校 1996 德成女大論文集 Vol.25 No.-

This article describes studies on sociomoral experiences promoting the college student's moral development. According to Kohlberg(1969), the special kinds of social experiences that are particularly conducive to development in moral thinking come from "role-taking" experiences. Moral developmentalist have had to be more concrete in operationalizing what particular experiences promote development. One of the strongest and most consistent correlates of development in moral judgement has been years of formal education, even more so than chronological age per se. Several waves of studies have been undertaken to better understanding the relation between formal education and moral judgement development, and more generally to understand what life experiences foster moral judgement development: study on activities, interests and life styles, on moral reasoning experiences, on characterization of life experiences, on a wide range of sociomoral experiences.