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Associations of serotonergic genes with poststroke emotional incontinence
Kim, Jae‐,Min,Stewart, Robert,Kang, Hee‐,Ju,Bae, Kyung‐,Yeol,Kim, Sung‐,Wan,Shin, Il‐,Seon,Kim, Joon‐,Tae,Park, Man‐,Seok,Cho, Ki‐,Hyun,Yoon, Jin‐ John Wiley Sons, Ltd 2012 INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY Vol.27 No.8
<P><B>Objectives</B></P><P>Poststroke emotional incontinence (PSEI) has been associated with serotonergic dysfunction. Polymorphisms of serotonin transporter (5‐HTT) and serotonin 2a receptor (5‐HTR2a) genes may regulate serotonergic signaling at brain synapses, and this study was to investigate associations with PSEI in an East Asian population.</P><P><B>Methods</B></P><P>In 276 stroke cases, PSEI was diagnosed by Kim's criteria. Covariates included age, gender, education, history of depression or stroke, current depression, and stroke severity and location. Genotypes were ascertained for 5‐HTT gene‐linked promoter region (5‐HTTLPR), serotonin transporter intron 2 variable number tandem repeat, 5‐HTR2a 1438A/G, and 5‐HTR2a 102 T/C. Associations with PSEI were estimated by using logistic regression models, and gene–gene interactions were investigated by using the generalized multifactor dimensionality reduction method.</P><P><B>Results</B></P><P>PSEI was present in 37 (13.4%) patients. The 5‐HTT gene‐linked promoter region <I>s</I>/<I>s</I> genotype was independently associated with PSEI. No associations with STin2 VNTR and 5‐HTR2a genes were found, and no significant gene–gene interactions were identified.</P><P><B>Conclusions</B></P><P>Stroke patients with 5‐HTTLPR <I>s</I> allele had higher susceptibility to PSEI, which underlines the potential role of serotonergic pathways in its etiology. Copyright © 2011 John Wiley & Sons, Ltd.</P>
서병성,김준연,김정만,김용규,정갑열,김성환,김인식,김병권 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3
This experiment was carried out to compare the efficacy of 2,3-dimercaptosuccinic acid(DMSA) and calcium ethylenediamine tetraacetate(CaEDTA) as chelating agents for lead poisoning. The rats had been fed water containing 0.5% lead acetate for 3 months and randomly divided into three groups. We administered DMSA only for group I(n=5), CaEDTA only for group II(n=5), and both DMSA and CaEDTA for group III(n=10), for 4 days. We evaluated urinary lead(PbU) level, blood lead(PbB) level and blood zinc protoporphyrin(ZPP) level before and after administration of the chelating agents. The results obtained were as follows; 1. After administration of chelating agents, the mean PbU levels, which were 248.2㎍/dl, 252.6㎍/dl and 270.0㎍/dl in group I, II and III before administration, were increased to 484.6㎍/dl, 479.9㎍/dl and 1,792.1㎍/dl in group I, II and III, respectively(p<0.05). 2. After administration of chelating agents, the mean PbB levels, which were 67.4㎍/dl, 59.9㎍/dl and 62.5㎍/dl in group I, II and III before administration, were decreased to 38.1㎍/dl, 36.3㎍/dl and 31.3㎍/dl in group I, II and III, respectively(p<0.05), but there were no different changes of ZPP level among groups. 3. The blood lead clearances, which were calculated by PbB level before and after administration of chelating agents, were 49.8%, 43.5% and 39.5% in group III, I and II, respectively.
야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로
조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6
Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.
김상열,박성태,신상욱,이명철 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4
보리후작 벼 부분경운직파기의 포장성능 평가와 벼 생육 및 수량영향을 조사하기 위해 실시한 연구결과는 다음과 같다. 1.부분경운직파 시작기의 파종시 종자 떨어짐 및 복토상태는 양호하나 배수골 넓이 및 깊이가 각각 17㎝, 10㎝로 좁고 배수골 양쪽벽이 무너져 배수골 안에 흙이 쌓이는 경향이었다. 2. 출아일수는 부분경운직파는 12일로 요철골직파보다 2일 늦었고, 입모수 및 파종 25일후 초장 변이계수는 부분경운직파가 요철골직파보다 큰 경향이었다. 3. 출수기는 부분경운직파는 8월 26일로 요철골직파보다 3일 늦었으나, ㎡당 수수, 수량구성요소 및 10a당 쌀수량은 요철골직파 및 부분경운직파에서 비슷하였다. 4.부분경운직파는 요철골직파에 비해 줄기매몰심이 깊고 도복지수가 낮아 요철골직파보다 도복이 적었다. Performance of minimum-tillage direct seeder and effect of the minimum-tillage direct seeding method on growth and yield of rice under barley-rice double cropping system was investigated. Seeding status of the minimum-tillage direct seeder was acceptable except for narrow irrigation canal formation and demolish of the seeding row in the barley straw added plot. In the minimum-tillage direct seeding, rice seedling emerged at 13 days after seed sowing, 2 days late compared with the corrugated dry furrow seeding method. The high variation in the seedling stand and seedling height at 25 days after seeding was occurred in the minimum-tillage direct seeding as compared with that of the corrugated dry furrow seeding. However, occurrence of the field lodging in the minimum-tillage direct seeding was lower than the corrugated dry furrow seeding method due to deep culm burial depth. Based on the milled rice yield, the two direct seeding methods showed similar with 432 ㎏ per 10a.
土壤水分別 播種期와 窒素施肥方法이 율무의 光合成과 生育 및 엽고병에 미치는 影響
金容撤,李忠烈,崔仁洙,朴賢哲,金成萬,林銖三 밀양대학교 농업기술개발연구소 2000 農業技術開發硏究所報 Vol.4 No.1
In order to establish optimal seeding date and nitrogen fertilization of adlay in barley-dlay cropping system of south-eastern part of Korea, yield and its components of adlay grown under at 3 different seeding dates and 2 nitrogen fertilizations were compared and analyzed. In addition, edible nutriants of adlay grain were compared with rice and woheat, between upland and paddy cultivation, and among three cultivars. The results obtained are summarized as follow: 1.Heading date and maturity date was fasted later seeding date than early seeding. Days to heading was decreased as the seeding date was delayed. 2.Stem leagth, stem diameter and No. of tiller were increased irrigation than control(non-irrigation), and was decreased as the seeding date was delayed. 3.Top and root dry weight were increased moisture were decreased irrigation than control(non-irrigation), and was decreased as the seeding date was delayed. 4.Net photosynthetic rate was increased at treatment of irrigation. Key word : adlay, seeding daye, soil water content, photosynthesis, growth.
근골격계 질환 예방을 위한 재생타이어 트레드 버핑머신 개발
김재열,한재호,이연신,김항우,오성민 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-
As a part of environmental pollution prevention and resources recycling, the regeneration of waste tire has been largely contributed to national industry. But, the worker has been evaded this regeneration process by reason of the best mischievous process condition among 3D industries.So, the first, the process condition of regeneratingwaste tire was analyzed. The second, the equipment or system was developed for the improvement of working strength and environment. The last, researchers intend to solve these problems
근골격계 질환 예방을 위한 재생타이어 트레드 버핑작업 개선에 관한 연구
김재열,한재호,이연신,김항우,오성민,송경석 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-
As a part of environmental pollution prevention and resources recycling, the regeneration of waste tire has been largely contributed to national industry. But, the worker has been evaded this regeneration process by reason of the best mischievous process condition among 3D industries.So, the first, the process condition of regeneratingwaste tire was analyzed. The second, the equipment or system was developed for the improvement of working strength and environment. The last, researchers intend to solve these problems