이하선에 발생한 상피-근상피암종 1예

도남용,박성용,임태승 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2

Epithelial-myoepithelial carcinoma (EMC) is a uncommon disease of salivary gland, occurring predominantly in the parotid gland and shown as painless mass. EMC is a tumor composed of variable proportions of two cell types that typically form ducHike structures, It has a mixture of trabecular structure with doubleUlayered arrangement of inner ductal cells and outer myoepithelial cells. We experienced a epithelialUmyoepithelial carcinoma of the left parotid gland treated with total parotidectomy and report it with the review of the literature.

자궁선근증의 고찰

조환성,이해혁,정성윤,김성욱,이순곤,남계현,이임순,이권해 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Objective: This study was designed to estimate the frequency and risk factor for edenomyosis Methods: The clinical records of 623 women undergoing hysterectomy were retrieved in the Department of Obstetrics and Gynecology, Soonchunhyang University Hospital, during 5 years, from Jan. 1995 to Dec. 1999. Results: The following result were obtained. 1. Adenomyosis was found in 247 of 623 patients(39.6%) 2. The highest incidence was 40-49 years of age group, an incidence of 46.6% and mean age was 44.7 years. 3. Adenomyosis was more frequently observed in parous women than non-parous women, such as 93.1% and 6.9%, respectively. 4. Dysmenorrhea, metrorrhagia, pelvic pain and vaginal bleeding were common symptom of adenomyosis, an incidence of 28.7%, 19.0%, 18.2% and 16.2%, respectively. 5. Myoma was the most combined disease in adenomyosis, showing the incidence of 54.7%. 6. Grossly, the size of uterus was enlarged more than 10 weeks gestational size in adenomyosis, an incidence of 61.9%. 7. Preoperative diagnostic accuracy of adenomyosis was 6.9%. Conclusion: The results show that deeply understanding of the common symptoms and epidemiology of adenomyosis improve the preoperative diagnostic accuracy.

한국 여성스포츠 활성화를 위한 연구

윤상화,남동현,조임형 龍仁大學校 1997 용인대학교 논문집 Vol.13 No.-

Historically women have been discriminated not only in sports but also in another fields of social life according to the social cultural backgrounds and customes. This sex discrimination is due to the lack of the opportunity to participate sports, the ideological prejudice of male diversionism and the systematic inequality uttered in the nomological, institutional, environmental aspects of society. And the social conception on male adventage and female dependence enforces the present discrimination in the women sports. Theoletically, discussion on women sports has been focused on the dogma that man governs woman in the sense of sex inequility in sports, limitation of female opportunity in sports, inequility of conservative system and the relative deprival of employment opportunity from the point of liberal, marxist, radical, socialist view. The sex discrimination is due to the social, cultural circumstance of a specific society and prejudicial cultural tradition. The cultural tradition form the idea that woman can play the role only through the family and companion because of her biological and depentent character and enforce such a sex role and social training. The social-role prejudice which began in the family and companion would be enforced and magnified through the discrimitive management of the curriculum and phisical education program at school. The sex discrimination has such a tendency of aggravation and perpetuity because of male-prejudicial news and scarcity of role-model, which have been discussed in many researches. But woman's sports were advanced quite much in accordance with feminism movements and the change of social/cultural definition on woman. In spite of all of these, there still appears to be some prejudice in the psyological, social-psychological, institutional realms. To sum up the factors which prevent woman's sports activate, Firstly, negative cognition of common people on woman's sports. Secondly, the prejudice that women are not adquite for sports activity. Thirdly, women themselves have the prejudice that sports activity makes their body manly. And to sum up the important theoletical factors concerned with the woman's sports activation, Firstly, woman has psychologically the stronger emotional intentionality than man. Secondly, woman has the weaker motivation for sports psychologically, which is due to her parents' indifference and the incorrect belief of 'womanlikehood' or 'out to be womanlike' and so on. Thirdly, because woman's participating the sports activity is influenced by intermediate group like family, the opportunity-situation became the important variable. Some conclusion for activation of Women's Sports Activation acquired in the study is as shown in the followings. Firstly, We must change the ineffective sports activities in the whole society, including the system, which places the importance in the examination at the existing school, and the physical education program which lays stress on the sudents to comply with the characteristics and interests of women in the scope of life-time sports, and the education on the leader who controls these programs effectively is urgent. Secondly,Mass Media must be interested in the sports, physical education activities of women, and show the positiveness on the program related to the women's own improvement and culture and on the public-information related to the concrete practical method.

자기 효능의 개념 분석

서순림,이은남,박송자,양영희,이동숙,최은옥,구미옥,김인자,이인숙,김성재,박영임,이은옥 서울대학교 간호대학 간호과학연구소 1997 간호학 논문집 Vol.11 No.1

Today human needs for health promotion and maintenance are increasing. The nursing progression has a great responsibility for helping clients to practice good health behavior. self efficacy was found to be potent predictor in initiating and maintaining the health-related behavior. Therefore, the concept is important in nursig intervention for change of health behavior. The purpose of this paper was to analyze and clarify the meaning of the concept, self efficacy. This study used Walder & Avant's process of concept analysis. Critical attributes of self efficacy were : 1) positive perception of his won capability; 2) intrapersonal strength; 3) possibility of being learned; 4) individuality; 5) specificity; 6) generalizability. Antecedents of self efficacy consist of those facts that 1) new situation occurs; 2) individuals have needs to change the new situation; 3) there are some required actions in new situation. Consequences occurring as a result of self efficacy consist of those facts that 1) individual initiates the of failure; 5) cope with the situation; 6) controls the situation; 7) the level of self efficacy is enhanced; 8) the level of self-esteem is enhanced.

사회환경교육의 교육과정 표준화 모형 및 통합프로그램 개발연구

박석순,최돈형,성효현,허명,강명희,이숙임,남상준 이화여자대학교 환경문제연구소 1998 이화환경연구 Vol.2 No.-

This paper presents the development of standardized modules and an integrated program which will be used for social environmental education. The study objectives are to develop modules which are based on various environmental topics, to relate the regional environmental topics to the educational modules and program, and to include the demand of students in the modules and program. Literature and questionary surveys, as well as, module development method were utilized as research tools. The titles of developed modules are "The Green Plant Earth," "Unexpected Resources: Save Resources and Recycle", "Water as the Mother of All Lives", "The Blue Sky with Clean Air", and "Soil as the Home of All Living and Non-living Things". It is hoped that the developed modules and program are utilized as course materials and curriculum for social environmental education in various educational institutes. The study results will be materialized as multimedia in near futher.

일반인의 환경문제 의식과 사회환경교육의 필요성에 관한 연구

허명,최돈형,박소현,성효현,박석순,남상준,이숙임 이화여자대학교 환경문제연구소 1998 이화환경연구 Vol.2 No.-

Today, the gobal community is confront serious environmental crisis derived from related problems energy and resources. To deal this crisis, people must take action in order to preserve current environment with ecological understanding of the relationship between human and environment. The principle of this thesis is to observe public endeavor toward environmental education program, environmental perception and environmental preservation behavior, and the influential factors to those conducts. First of all, we will look into the perception toward environmental deterioration, environmental perception, environmental preservation behavior which thought to be a ground solution to lesson the problems, and then the environmental education program. In accordance with those research, it will be presented the feasible directions of environmental education program for general public. This research consists of 10 topics. The topics are the interests of public about environmental problem, perceived pollution level, general knowledge about environment, perception related to environmental problem, opinions about the environmental education program, attitude towards environmental organization, suggestions for future environmental education program, and campaign for environmental preservation. Through the research, we have reached some analytical conclusions are followed: First, the level of public concerns about environmental problems is high regardless its age and sex, and the level has been growing compared to the past one. The result also shows that people in urban and industrial areas feel much more seriously pollution problems than those in rural and coastal areas. In addition, according to the survey result, household and industrial sewage are regarded as the primary causes for water pollution. Secondly, the results show general public's understanding on environment have been universalized and thus the level of common knowledge on global environment has been increased, as environmental problems have been raised by newspapers and mass medias and various movements have been accomplished by environmental protection organizations. Thirdly, although the necessity of environmental education was emphasized the purpose of environmental education was unclearly appeared. Furthermore, actual participation to the environmental education program and taking courses by joining environmental organizations were rarely shown. Although some cases have the experience of taking education courses, the negative reactions came out in the opinion of education content and methodologies. Fourthly, the analysis on curriculum of future environmental education show various opinions. The attentions have drawn on the dealings of waste industrial and chemical waste which will cause environmental problem artificially, as well as on global environment, or natural environment such as resources, land, water, atmosphere. The results show many people recognized administration extent such as environmental policy, law and ethics as environmental categories. This implies the curriculum of those areas have not been properly founded and further researches should be followed. From above results, environmental problems should not be regarded as simple problems and it should bring out new recognition for general public in everyday life. In addition, environmental education courses, with practical environmental preservation should be developed and programs and organization which will utilize those educational materials should be more activated.

2형 당뇨 환자에 있어서 C형 간염의 유병률에 관한 연구

김구영,서광섭,유광렬,임병욱,채선애,강남훈,김창훈,권영우,김희수,류성태,이정환,박성우,오웅식,김정한 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.1

Background: We have doubt about the truth that Type 2 DM is associated with chronic hepatitis C infection. The aim of our study was to prove a close relationship between chronic HCV infection and type 2 DM in korean patients. Methods: We reviewed the out-patient's medical records of 466 patients with type 2 DM who visit the Sung-ae hospital from March 2000 to August 2001. Diabetic patients were analyzed for the following variables: age, sex, waist circumference, weight, waist/hip ratio, using of self monitoring of blood glucose, method of therapy, duration of disease, experience of previous transfusion, major surgical procedure, accompanied disease, liver function tests (LFT), HbA1 c. We ruled out patients with liver cirrhosis. Results: Hepatitis C virus infection was observed more frequently in patient with Type 2 DM. Of 466 Type 2 DM patients, 13 patients were infected with Hepatitis C virus (2.79%). Compared with mean prevalence of Korean population (1.3~1.6%), it's value is very high. the other hand, 21 patients were infected with Hepatitis B virus (4.5%). Such results are similar to mean prevalence of the general public (4~5%). Conclusions: Prevalence of hepatitis C was closely associated in korean patients with type 2 DM. And an increased prevalence is independent of cirrhosis.

Medicinal Chemistry : Spatholobus suberectus Inhibits Osteoclastogenesis and Stimulates Chondrogenesis

( Nam Kyung Im ),( Sung Gyu Lee ),( Dong Sung Lee ),( Pil Hoon Park ),( In Seon Lee ),( Gil Saeng Jeong ) 영남대학교 약품개발연구소 2015 영남대학교 약품개발연구소 연구업적집 Vol.25 No.-

THis study was carried out to investigate the effect of Spathololbus suberectus Dunn(SS)on the protection of chondral defect and inhibition of osteiclastogenesis. To examine these effecte,we measured the matrix metalloproteinase(MMP)levels in SW1353 chon-drosarcoma cells and performed tartrate-resistant acid phossohatase (TRAP) staining in bone marrow macrophage(BMM)-derived osteoclasts.To investigate the anti-osteoarthritis(OA)effects,we assessed TNF-α-induced MMP-1,-3,-9 and tissue inhibitors of matrix metal- loproteinase(TIMP)expression levels in SW 1353 cells.Also,SS extract inhibiteb the receptpr activator of unclear factor-kB ligand(RANKL)-induced osteoclast differentia- tion. These results suggest that SS extract may have a potential in the treatment of bone loss and chondral defectby suppressing osteoclast differentiation and decreasing the expression of OA factors. Therefore, clarification of the mechanism of the action of SS extract and its active components is needed.

Spatholobus suberectus inhibits osteoclastogenesis and stimulates chondrogenesis.

Im, Nam-Kyung,Lee, Sung-Gyu,Lee, Dong-Sung,Park, Pil-Hoon,Lee, In-Seon,Jeong, Gil-Saeng Institute for Advanced Research in Asian Science a 2014 The American journal of Chinese medicine Vol.42 No.5

<P>This study was carried out to investigate the effect of Spatholobus suberectus Dunn (SS) on the protection of chondral defect and inhibition of osteoclastogenesis. To examine these effects, we measured the matrix metalloproteinase (MMP) levels in SW1353 chondrosarcoma cells and performed tartrate-resistant acid phosphatase (TRAP) staining in bone marrow macrophage (BMM)-derived osteoclasts. To investigate the anti-osteoarthritis (OA) effects, we assessed TNF-α-induced MMP-1, -3, -9 and tissue inhibitors of matrix metalloproteinase (TIMP) expression levels in SW1353 cells. We observed that SS extract significantly inhibited MMP and TIMP expression in SW1353 cells. Also, SS extract inhibited the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast differentiation. These results suggest that SS extract may have a potential in the treatment of bone loss and chondral defect by suppressing osteoclast differentiation and decreasing the expression of OA factors. Therefore, clarification of the mechanism of the action of SS extract and its active components is needed.</P>

Prediction of Hepatocellular Carcinoma by On-Therapy Response of Non-Invasive Fibrosis Markers In Chronic Hepatitis B

( Heechul Nam ),( Sung Won Lee ),( Jung Hyun Kwon ),( Hae Lim Lee ),( Sun Hong Yoo ),( Hee Yeon Kim ),( Do Seon Song ),( Pil Soo Sung ),( U Im Chang ),( Chang Wook Kim ),( Soon Woo Nam ),( Si Hyun Bae 대한간학회 2021 춘·추계 학술대회 (KASL) Vol.2021 No.1