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      • 조기진통의 진단과 처치

        성문수,김현찬 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Prematurity and intra-uterine growth retardation(IUGR) and two main cause of low birth weight(LBW), a major contributor to infant mortality. The majority of LBW infants in developing countries is due to IUGR, while most LBW infants in industrialized countries are due to preform birth. The preform birth rate of almost 10% of birth has remained little changed for several decades, despite in changes in clinical practice and technology. Between 75~80% of those deliveries are due to either preform labor or preform prematurity of membranes. There is not yet complete understanding of the cause of preform labor. Preventive and treatment efforts aimed at single etiology have been unsuccessful to date, since the cause are multifactorial. Accurate diagnosis of preform labor remains a problematic issue. New techniques such as transvaginal cervical sonography and fetal fibronectin are increasingly important in diagnosis and intervention planning. Neither test can, at present, recommended for screening of general population since there is no effective intervention for a positive test. Future directions in research include development of new tocolytic agents and clarification of the best use of adjunctive therapies for lung maturity.

      • KCI등재
      • KCI등재

        임플란트의 collar design이 변연골과 연조직에 미치는 영향

        유현상,강선녀,정창모,윤미정,허중보,전영찬 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

        연구 목적: 임플란트 경부가 잘 설계된 경우 양호한 연조직 반응을 통해 변연골을 보존하는데 도움이 된다. 본 실험에서는 연, 경조직 경계부에 가장 가까이 위치하는 임플란트의 collar design이 변연골 변화와 연조직 반응에 미치는 영향을 동물실험을 통해 알아보고자 하였다. 연구 재료 및 방법: 2마리의 건강한 Beagle dog에 임플란트 collar design만 다른 두 종류의 임플란트(Neobiotech Co. Seoul, Korea)를 식립하였다. Collar에 bevel 을 부여한 군(Bevel 군)과 "S"자 형태를 부여한 군(Bioseal 군)으로 나누어 마리 당 7개, 군당 7개, 총 14개의 임플란트를 무작위로 식립한 후 Healing abutment를 즉시 체결하였다. 디지털 표준구내 방사선사진을 이용해 4주 간격으로 총 12주간 근원심 변연골 변화를 관찰하였고, 12주에 희생하여 조직학적 분석을 통해 협설 변연골 흡수 및 임플란트 주변 연조직 반응을 평가하였다. Mann-Whitney test를 통해 동일한 방사선 사진 촬영 시점에서 근원심 변연골 변화량 및 조직계측치를 군 간 비교하였고, Kruskal-Wallis test를 통해 방사선 사진상 근원심 변연골 변화량이 시간에 따른 차이가 있는지 군 내 분석 한 후 Duncan test를 통해 사후 검증하였다(α=.05). 결과: 방사선학적 분석 결과 각 촬영 시점에서 두 군간 근원심 변연골 변화량의 차이를 보이지 않았다(P>.05). 군 내에서 시간에 따른 근원심 변연골의 흡수량을 분석한 결과 Bevel 군에서는 시간에 따른 차이를 보이지 않았으나 (P>.05), Bioseal 군에서는 시간에 따른 차이를 보였으며, 4주및8주와 비교했을 때 12주에서 변연골의 증가를 보였다(P<.05). 조직학적 분석 결과 협설측 변연골 흡수량에서 두 군간 차이를 보이지 않았으나 (P>.05), Bevel 군에 비해 Bioseal 군에서 더 견고한 결합조직부착을 관찰할 수 있었으며, 생물학적 폭경의 값은 두 집단 간 차이를 보이지 않은 반면에 (P>.05), 접합상피부착은 Bevel 군에서 유의하게 길었고, 결합조직부착은 Bioseal 군에서 더 길게 나타났다(P<.05). 결론: Bevel 군에 비해 Bioseal 군에서 결합조직부착은 길게 형성된 반면에 접합상피부착은 더 짧게 나타났으며, 생물학적 폭경과 초기 변연골 흡수에는 차이가 없음을 알 수 있었다. 연조직 반응의 차이가 실제 기능하중 하에서 변연골 변화에 미치는 영향에 대해서 향후 연구가 필요할 것으로 생각된다. PURPOSE. The purpose of this study was to investigate the effects of implant collar design on marginal bone change and soft tissue response by an animal test. MATERIALS AND METHODS. Two types of Implant (Neobiotech Co. Seoul, Korea) that only differs in collar design were planted on two healthy Beagle dogs. The implants were divided into two groups, the first group with a beveled collar (Bevel Group) and the second group with "S" shaped collar (Bioseal group). Standardized intraoral radiographs were used to investigate the mesio-distal change of the marginal bone. Histological analysis was done to evaluate the bucco-lingual marginal bone resorption and the soft tissue response adjacent to the implant. Mann-Whitney test was done to compare the mesio-distal marginal bone change at equivalent time for taking the radiographs and the tissue measurements between the groups. RESULTS. Radiographic and histological analysis showed that there was no difference in marginal bone change between the two groups (P>.05). Histological analysis showed Bioseal group had more rigid connective tissue attachment than the Bevel group. There was no difference in biological width (P>.05). Bevel group showed significantly longer junctional epithelium attachment and Bioseal group showed longer connective tissue attachment (P<.05). CONCLUSION. For three months there were no differences in marginal bone change between the Bevel group and the Bioseal group. As for the soft tissue adjacent to the implant, Bioseal group showed longer connective tissue attachment while showing shorter junctional epithelium attachment. There were no differences in biologic width.

      • 해수중 화학원소의 거동과 생물활동

        현상민,최영찬 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-

        The concordant variation between chemical elements and biological activity in seawater is reviewed in this paper. The flux of the biogenic components in seawater is highly linked up with the flux of the lithogenic materials or vise versa. indicating that suspended clays. fine fractions and chemical elements are efficiently scavenged through the water column by sinking organic aggregates. Most of chemical elements in seawater are formed as complexation. suggesting that the biological activity in seawater plays an important role in becoming a complex form of chemical elements. Therefore, it is necessary to study the form of chemical elements and their behavior with respect to biological activity. Understanding the linkage between the biological activity and the behavior of chemical elements in seawater is the first step to explore oceanic environmental change including material cycles in sea water.

      • 각막굴절수술(라식) 환자에 대한 경향성 분석

        성아영,김찬수,이석주,조수현 대불대학교 2002 論文集 Vol.8 No.1

        Now a days, LASIK(laser in situ keratomileusis) surgical operation is enforced widely by method that is used to correct ametropia such as near-sightedness, far-sightedness, astigmatism etc. This wishes to solve troublesome matter for glasses and contact lens wearer that reform a part of corneal stroma by laser after using microkeratome in which make corneal flap. This experiment present that refraction by auto-refractometer in point of time before and after a week to those who undergone LASIK surgical operation 30 patients. 60 eyes that become full corrected(spherical power : +0.50D∼-0.50D). By this research method, in point of time that examination has a week after operation because of refraction power changed by passage of time and classified by sex, age, occupation, and degree of myopia(low:-1.0D∼-3.0D, moderate: -3.0D∼-6.0D, high :more than -6.0D). As a result of this study LASIK surgery can solve uncomfortableness by wearing glasses or contact lens, but the result objectively doesn't meet satisfaction level though full correction had made.

      • 위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

        김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

      • KCI등재

        분뇨처리장의 공정개선에 의한 처리효율 향상에 관한 연구

        이찬원,김승현,김창수,문성원,전홍표,윤종섭 한국환경과학회 2004 한국환경과학회지 Vol.13 No.6

        There is a need to improve the efficiency of the existing sanitary treatment facilities, because the effluent standard becomes more stricter and septic sludge increased. Thus, operating processes of sanitary treatment system in M city changed with installation of additional facilities. Process modifications were as follows: Dilution water was added to the next process after primary aeration tank. Some secondary sedimentation sludge was recycled to primary aerator so that most of the organics were stabilized in primary aeration tank under automatic control of dissolved oxygen. The line of effluent from dewatering process flowing to the activated sludge tank was changed to the primary aerator. The primary sedimentation sludge line was linked to a thickener. Polymer was added to the activated sludge tank. The effluent of primary aerator and aerobic digester was recycled from the 5th to the 1st sector. As consequencies of above process modifications, the improvement of removal efficiency was achieved as BOD 54%, COD 42%, SS 61%, T-N 39%, and T-P 12%, respectively.

      • TDMA 셀룰라 시스템에서 개별-탭 계수를 이용한 적응 등화기에 관한 연구

        홍성수,박래수,한현택,김학춘,정찬주,나상동 조선대학교 동력자원연구소 1995 動力資源硏究所誌 Vol.17 No.1

        Demodulation wants to adaptive equalizer to minimize interference of intersymbol which generate in multipath fading channel results from signal time and variety multi propagation through channel in digital radio network systems. Therefore using transition ratio of transfer and receiver system and the number of forward and backward using existing individual taps, we study improvement algorithms which generated bit error ratio by signal in frequence select fading. We analysis and compare linear equalizer and decision feedback nonlinear equalizer. Proposed algorithm is more efficent in fading environment when compared of step size by channel character which estimated existing least square and ITLMS algorithm. In this paper, using ITLMS algorithm by decision feedback BER is reduced for intersymbol interference by narrowband TDMA multipath fading in invironment without individual tap weight overlay.

      • 위발성 위장관 악성림프종 환자에서 항암치료의 효과

        김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

        Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

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