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Jaehyeon Seo,Jaeman Son,조연아,Noh-Won Park,김동욱,김진성,Myonggeun Yoon 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.4
Radiotherapy for the treatment of cancer in companion animals is currently administered by using megavoltage X-ray machines. Because these machines are expensive, most animal hospitals do not perform radiotherapy. This study evaluated the ability of relatively inexpensive kilovoltage X-ray machines to treat companion animals. A simulation study based on a commercial treatment-planning system was performed for tumors of the brain (non-infectious meningoencephalitis), nasal cavity (malignant nasal tumors), forefoot (malignant muscular tumors), and abdomen (malignant intestinal tumors). The results of kilovoltage (300 kV and 450 kV) and megavoltage (6 MV) X-ray beams were compared. Whereas the 300 kV and 6 MV X-ray beams provided optimal radiation dose homogeneity and conformity, respectively, for brain tumors, the 6 MV X-rays provided optimal homogeneity and radiation conformity for nasal cavity, forefoot, and abdominal tumors. Although megavoltage X-ray beams provided better radiation dose distribution in most treated animals, the differences between megavoltage and kilovoltage X-ray beams were relatively small. The similar therapeutic effects of the kilovoltage and 6 MV X-ray beams suggest that kilovoltage X-ray beams may be effective alternatives to megavoltage X-ray beams in treating cancers in companion animals.
Feasibility Study of Beam Angle Optimization for Proton Treatment Planning Using a Genetic Algorithm
Seo Jaehyeon,Jo Yunhui,Moon Sunyoung,Yoon Myonggeun,안성환,Lee Boram,Chung Kwangzoo,Jeong Seonghoon 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.77 No.4
This study describes a method that uses a genetic algorithm to select optimal beam angles in proton therapy and evaluates the effectiveness of the proposed algorithm in actual patients. In the use of the genetic algorithm to select the optimal angle, a gene represents the angle of each field and a chromosome represents the combination of beam angles. The fitness of the genetic algorithm, which represents the suitability of the chromosome to the solution, was quantified by using the dose distribution. The weighting factors of the organs used for fitness were obtained from clinical data through logistic regression, reflecting the dose characteristics of actual patients. Genetic operations, such as selection, crossover, mutation, and replacement, were used to modify the population and were repeated until an evaluation based on fitness reached the termination criterion. The proposed genetic algorithm was tested by assessing its ability to select optimal beam angles in three patients with liver cancer. The optimal results for fitness, planning target volume (PTV), normal liver, and skin in the population were compared with the clinical treatment plans, a process that took an average of 36.8 minutes. The dose-volume histograms (DVHs) and the fitness of the genetic algorithm plans did not differ significantly from the actual treatment plans. These findings indicate that the proposed genetic algorithm can automatically generate proton treatment plans with the same quality as actual clinical treatment plans.
배기열 재순환 시스템을 이용한 엔진 및 ATF의 급속 웜업에 따른 연비향상에 관한 연구
이재현(Jaehyeon Lee),이헌균(Heonkyun Lee),서영호(Yeongho Seo),김태진(Taejin Kim) 한국자동차공학회 2011 한국자동차공학회 부문종합 학술대회 Vol.2011 No.5
The reality is that fuel efficiency regulations to strengthen regulations and restrictions on green house gas emissions in the transportation sector worldwide. In response policies that enhance fuel efficiency, powertrain technology and temperature control of cooling water in cooling efficiency technologies fast Warm-up technology that improves fuel economy simultaneously at low temperature. Technology for rapid warm-up, the hot exhaust recirculation system (EHRS: Exhaust Heat Recirculation System) technology offers. In this study, utilizing engine exhaust heat to be abandoned EHRS use the system, Coolant and ATF’s Warm-up to evaluate the performance of the vehicle fuel consumption and emissions by reducing the time.
영남육괴 남서부 안의도폭 지역 초기 쥬라기 변형 화강암류의 SHRIMP U-Pb 연대
서재현,송용선,박계헌,Seo, Jaehyeon,Song, Yong-Sun,Park, Kye-Hun 대한자원환경지질학회 2016 자원환경지질 Vol.49 No.2
남서부 영남육괴 안의도폭 지역의 변형 화강암류에 대한 SHRIMP U-Pb 연대측정을 수행하였다. 선캠브리아 편마암으로 알려진, 현저하게 변형된 호상구조를 보이는 압쇄조직의 화강암과 비교적 약하게 변형된 반상 내지 안구상의 화강암 각각 한 개씩의 시료에서 분리된 저어콘에 대한 연대측정 결과는 약 195 Ma로 연대가 동일하였다. 이 연구 결과와 기존의 연대자료에 의해 안의도폭 주변부 지역에서의 중생대 초-중기 화성활동은 다음과 같이 해석되었다: 트라이아스 중기(약 225-219 Ma)에 섭입관련 화강암질 마그마작용이 주로 서부지역에서 함양 화강암의 관입으로 시작되었고 트라이아스 말기(약 220-210 Ma)에 섬장암질 관입으로 끝났다. 비교적 짧은 휴지기 후에, 쥬라기 초기인 약 195 Ma에 이번 연구에서 연대가 측정된 변형 화강암류를 생성한 마그마의 관입으로 화강암질 마그마작용이 다시 시작되어 약 189 Ma까지 계속되었으며, 화강암질 마그마작용의 말기에는 섬록암류의 관입이 수반되었다. SHRIMP U-Pb age determination was carried out for deformed granites in the Aneui quadrangle, SW Yeongnam Massif. Dating of zircons from a highly deformed mylonitic granite with banded structure and a relatively less deformed porphyritic to augenic granites, that were known as Precambrian gneisses, yielded the same age of ca. 195 Ma. On the basis of this result and previous age data, Early to Middle Mesozoic igneous activity around the Aneui area was interpreted as follows; Subduction-related granitic magmatism started with the intrusion of the Hamyang Granite in the middle Triassic (ca. 225-219 Ma) mainly in the west of the area and ended with syenitic intrusion at the end of Triassic period (ca, 220-210 Ma). After a relatively short period of quiescency, granitic magmatism restarted with the intrusion of magma forming deformed granites dated in this study at the Early Jurassic of ca. 195 Ma and continued to ca. 189 Ma and dioritic intrusion was associated around the late stage of granitic magmatism.