경사진 트레드밀에서 후방보행운동을 통한 넙다리네갈래근 강화와 요통의 관계

박주완,김경,김형욱,김재우,배솔희,서정표,이정구,정하영 대구대학교 특수교육재활과학연구소 2010 再活科學硏究 Vol.28 No.1

목적: 본 연구에서는 경사진 트레드밀에서의 후방 보행 훈련을 통한 넙다리네갈래근의 강화가 요통 환자의 치료에 미치는 영향을 알아보고자 하였다. 대상: 만성 요통을 호소하는 16명의 환자를 대상으로 연구를 실시 하였다. 방법: 트레드밀을 10° 경사로 맞춰놓은 상태에서 대상자들은 하루 20분, 일주일에 3회의 빈도로 2주 동안 훈련을 하였다. 표면 근전도를 가지고 넓다리 곧은근, 안쪽 넓은근, 가쪽 넓은근, 척추 세움근의 %MVIC를 측정하였고, KODI와 VAS를 통해 대상자들의 통증정도를 측정하였다. 결과: 넓다리 곧은근은 훈련전에 비해 훈련을 하고 난 후 상대적으로 높은 근전도를 보였고, 통계적으로 유의하였다(p<.05). 안쪽 넓은근과 가쪽 넓은근 또한 높은 근전도율을 보였지만 통계적으로 유의하지는 않았다. 척추 세움근은 훈련전에 비해 훈련을 하고 난 후 높은 근전도율을 보여주었고, 통계적으로 유의하였다(p<.05). VAS와 KODI의 평균값은 명백하게 감소되었고, 통계적으로 유의하였다(p<.05). 결론: 이상의 결론을 종합하면, 후방보행을 통한 넙다리네갈래근의 강화는 요통의 감소에 효과적이라고 사료되며, 더불어 넙다리네갈래근으로 접근하여 요통을 경감하는 중재방법이 효과적인 치료 방법이 될 수 있다는 것을 의미한다. Purpose: This study was to investigate the influence of strengthening the Quadriceps femoris through backward walking treadmill training in the patients who have lower back pain. Subjects: Sixteen subjects with chronic lower back pain were included. Method: In the training, the treadmill was set to have a inclination of 10 degrees, and the subjects were trained for 20 minutes a day, 3 times a week, for 2 weeks. %MVIC(muscle power) of rectus femoris, vastus medialis oblique, vastus lateralis and erctor spinae were measured with surface EMG, and KODI and VAS were used to measure the subject's level of pain. Results: Quadriceps femoris showed relatively higher average electromyogram rates than that before training(p<.05). Vastus medialis oblique and vastus lateralis also showed higher average electromyogram rates, but no significant change in them was noted. Erector spinae showed higher average electromyogram rates than that before training(p<.05). The average points of VAS and KODI clearly decreased(p<.05). Conclusion: Strengthening Quadriceps femoris seems to be efficient for relieving lower back pain in this study.

양파(Allium cepa L.)의 항고지혈 및 항산화 활성에 관한 연구

정명현,이병주,김경완 朝鮮大學校 1998 藥學硏究誌 Vol.19 No.2

This Study was attempted to investigate the effect of Mum cepa L. (onion) on the activities of GOT and GPT. the levels of total lipids. triglyceride. total cholesterol. phospholipid and β-lipoprotein in the serum and the increase ratio of body and liver weight in the experimentally induced hyperlipemic rats. The activities of S-GOT and S-GPT were significantly decreased in dose of onion juice 3 ml and 5 head as compared to the high lipid-diet control group. The levels of total lipids, triglyceride. total cholesterol and phospholipids were significantly decreased in dose of onion juice 3 ml and 5 ml/head as compared to the control group. respectively However. the level of β-lipoprotein was significantly decreased in dose of onion juice 3 ml/head. The levels of triglyceride and total cholesterol m the Liver were significantly decreased in dose of onion juice 3 ml/head. Increase ratio of the body and liver weight were significantly decreased in dose of onion juice 3ml/head. Anti-fatigue activity of onion juice were studied in mice using the swimming performance method. The potencies of anti-fatigue activities was significantly found in 1.2 ml/head. p.o. of onion juice. The methanol extract and juice extract of onion was significantly found to be an antioxidative activity on the air oxidation of linoleic acid as compared to the 3-butyl 4-hydroxyanisole and α-tocopherol.

고지방식을 섭취한 랫드에서 김치유산균의 콜레스테롤 저하효과

조미선, 노정미, 임형준, 한선경, 신명수, 이완규 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

충수염의 임상적 고찰과 초음파의 유용성

박정배,양혁준,김형수,황성연,박철완,이근 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Appendicitis is the most common acute abdomen in Emergency Medical Center & outpatient department. But sometimes, it is difficult for us to diagnose because of clinically variable symptoms. We reviewed the ultrasonographic findings and analyse 521 cases of appendectomy patients about its distribution of sex and age, seasonal prevalence, clinical symptom and signs, laboratory findings, duration from onset of symptom to arrival at hospital, duration from arrival at hospital to operation, vital signs, operative results, and associated diseases, which were treated at the department of General Surgery & Emergency Medical Center in Chung Ang Gil Hospital from July, 1994 to June, 1995. The results were as follows : 1. The most common age group was second decade. And male to female ratio was 1.43:1. Seasonal variation was not significant. 2. Of 521 cases, 141 cases(27.1%) visited the hospital within 24 hours from the onset of symptom, and 259 cases(49.7%) visited between 24 to 48 hours. 3. In duration from arrival to operation, the cases within 6 hours were 263 (50.5%), the cases between 6 and 12 hours were 131(25..1%). 4. In systolic blood pressure, cases below 90mmHg were 19(3.6%), cases above 160mmHg were 23(4.4%). Below 60mmHg diastolic pressure were 55 cases(10.6%), cases above 110mmHg were 9(1.7%). In pulse rate, above 90 rate/min were 171(32.8%). 5. On admission leukocytosis was found in 413 cases(79.3%) and 342 cases of them were pathologic appendicitis. 6. Ultrasoundgraphy was performed in the 87 cases, but 23 cases were suggested appendicitis. Among 23 cases, 22(95.7%) revealed pathologic appendicitis at ooperation and labortatory examination. Of the 64 cases which were normal on ultrasonography, only 2 cases(3.1%) were proved to be appendicitis. 7. The results of 496 operations without ultrasonography were appendicitis in 390 cases(78.6%), mesenteric lymphadenopathy 36(7.3%), pelvic inflammatory disease 28(5.6%), fecalith 15(3.0%), terminal ileitis 8(1.6%), diverticulitis 7(1.4%), urinary tract stones 5(1.0%), cecal cancer 2 cases, right ovarian tumor 2 cases, tubo-ovarian abscess 2 cases, grater omentum internal hernia 1 case. Our results showed that the sensitivity of ultrasonohraphy was 95.8% and the specificity 98.4% in the diagnosis of appendicitis, It suggests that the ultrasonography is very helpful in the diagnosis & differential diagnosis of acute appeendiditis.

비유기중의 소유방염에 대한 항균펩타이드(Buforin Ⅱb)의 효능실험

김인송,권성균,임형준,이완규 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.3

Recently, a novel antimicrobial peptide including Buforin II has been emphasized to kill multi-drug resistant bacteria and avoid promoting multi-drug resistance. This study evaluated the efficacy of an antimicrobial peptide (Buforin IIb) on bovine mastitis. Based on the Minimum inhibitory concentration(MIC, 4 g/ml) of Buforin IIb, syringes were made five concentration(MIC×10, ×50, ×100, ×300, and ×500). Thirty three cows(38 quarters) with bovine mastitis were selected using California mastitis test and grouped in dependant on drug concentration and treatment duration. Each group treated by intramammary infusion twice a day for 3 5 days. The milk samples of 5 groups were aseptically collected from quarters at 0, 3, 7 and 14 days, and 2 groups were collected at 0, 5, 9 and 14 days after first treatment. Collected samples were used for bacterial culture and somatic cell count. Bacterial number(log_(10) mean CFU/ml) was decreased in dependant on drug concentration and extending treatment duration. In group D(MIC×300), bacterial number was decreased from 4.59±0.10(day 0) to 2.89±1.37(day 3), 4.04±0.33(day 7), and 4.19 ± 0.10(day 14), respectively(p 0.05). Bacterial number of B2(MIC×50, 5 days treated) is decreased, approximately 10%, than group B1(MIC×50, 3 days treated). Somatic cell count of group D was slightly decreased from 11,100(×10³)(day 0), to 7,386(×10³)(3 day), 6,886(×10³)(day 7), and 9,661(×10³)(day 14). Staphylococcus spp., was the most common isolate, was bacteriologically cured 100% by Buforin IIb treatment. Overall results indicate that Buforin IIb could have possibility to cure bovine mastitis, if higher concentration over experimental concentration were treated with extending treatment duration.

Evaluation of internal fit of interim crown fabricated with CAD/CAM milling and 3D printing system

Wan-Sun Lee,Du-Hyeong Lee,Kyu-Bok Lee 대한치과보철학회 2017 The Journal of Advanced Prosthodontics Vol.9 No.4

PURPOSE. This study is to evaluate the internal fit of the crown manufactured by CAD/CAM milling method and 3D printing method. MATERIALS AND METHODS. The master model was fabricated with stainless steel by using CNC machine and the work model was created from the vinyl-polysiloxane impression. After scanning the working model, the design software is used to design the crown. The saved STL file is used on the CAD/CAM milling method and two types of 3D printing method to produce 10 interim crowns per group. Internal discrepancy measurement uses the silicon replica method and the measured data are analyzed with One-way ANOVA to verify the statistic significance. RESULTS. The discrepancy means (standard deviation) of the 3 groups are 171.6 (97.4) μm for the crown manufactured by the milling system and 149.1 (65.9) and 91.1 (36.4) μm, respectively, for the crowns manufactured with the two types of 3D printing system. There was a statistically significant difference and the 3D printing system group showed more outstanding value than the milling system group. CONCLUSION. The marginal and internal fit of the interim restoration has more outstanding 3D printing method than the CAD/CAM milling method. Therefore, the 3D printing method is considered as applicable for not only the interim restoration production, but also in the dental prosthesis production with a higher level of completion.

Disorders of Small and Large Intestine : Expression Pattern Of E-And N-Cadherin In Colorectal Adenocarcinoma With Liver Metastasis

( Hyeong Cheon Park ),( Wan Sik Lee ),( Chang Hwan Park ),( Hyun Soo Kim ),( Sung Kyu Choi ),( Jong Sun Rew ),( Jae Hyuk Lee ),( Seok Lee ),( Sang Min Yum ),( Ho In Whang ),( Kyoung Won Yoon ),( Suck 대한소화기학회 2007 SIDDS Vol.9 No.-

Background Aims: Colorectal carcinoma (CRC) is known to be metastasized to the liver frequently and is the major cause of cancer-related death. Recent studies have identified several biomolecular alterations that influence prognosis after resection of liver matastases, including treatment-related and clinicopathologic factors. However, the relationship between the expression pattern of E- & N-cadherin and liver metastasis of CRC is poorly understood. Methods: The present study included 45 patients who underwent hepatic resection for colorectal hepatic metastasis. Immunohistochemical analysis of the expression of E- & N-cadherin protein was carried out for evaluating the metastatic potential of CRC. The methylation status of the E- & N-cadherin promoter was investigated by utilizing the methylation-specific polymerase chain reaction (MSP) assay in 45 patients. The correlation between E- & N-cadherin expression and clinicopathologic parameters was also analysed. Results: Abnormal E-cadherin expressions observed 42.2% (19/45) in primary cancers and 46.7% (21/45) in metastatic tumors. Abnormal N-cadherin expressions were noted 71.1% (32/45) in primary cancers and 82.2% (37/45) in metastatic tumors. Methylated alleles for E-cadherin presented 73.3% (33/45) in primary cancers and 64.4% (29/45) in metastatic tumors. Methylated alleles for N-cadherin presented 11.1%(5/45) in primary cancers and 8.9% (4/45) in metastatic tumors. Abnormal E-cadherin expression was significantly associated with hypermethylation of E-cadherin in primary CRC (P=0.036). Recurrence rate was significantly associated with liver mass size (>3 cm) and abnormal E-cadherin expression in liver (p=0.02). Survival rate was significantly associated with liver metastasis number (multiple)(p=0.01). Conclusions: Abnormal expression of E-cadherin was significantly associated with E-cadherin promoter methylation in CRC. Liver metastatic mass size and metastasis number were significantly associated with survival rate but E-cadherin, N-cadherin and methylation state in liver were not significantly associated with survival rate.

CAPS markers using mitochondrial consensus primers for molecular identification of Panax species and Korean ginseng cultivars (Panax ginseng C. A. Meyer)

Lee, Jei-Wan,Bang, Kyong-Hwan,Kim, Young-Chang,Seo, A-Yeon,Jo, Ick-Hyun,Lee, Jeong-Hoon,Kim, Ok-Tae,Hyun, Dong-Yun,Cha, Seon-Woo,Cho, Joon-Hyeong Springer-Verlag 2012 Molecular biology reports Vol.39 No.1

Evaluation of internal fit of interim crown fabricated with CAD/CAM milling and 3D printing system

Lee, Wan-Sun,Lee, Du-Hyeong,Lee, Kyu-Bok The Korean Academy of Prosthodonitics 2017 The Journal of Advanced Prosthodontics Vol.9 No.4

PURPOSE. This study is to evaluate the internal fit of the crown manufactured by CAD/CAM milling method and 3D printing method. MATERIALS AND METHODS. The master model was fabricated with stainless steel by using CNC machine and the work model was created from the vinyl-polysiloxane impression. After scanning the working model, the design software is used to design the crown. The saved STL file is used on the CAD/CAM milling method and two types of 3D printing method to produce 10 interim crowns per group. Internal discrepancy measurement uses the silicon replica method and the measured data are analyzed with One-way ANOVA to verify the statistic significance. RESULTS. The discrepancy means (standard deviation) of the 3 groups are $171.6\;(97.4){\mu}m$ for the crown manufactured by the milling system and 149.1 (65.9) and $91.1\;(36.4){\mu}m$, respectively, for the crowns manufactured with the two types of 3D printing system. There was a statistically significant difference and the 3D printing system group showed more outstanding value than the milling system group. CONCLUSION. The marginal and internal fit of the interim restoration has more outstanding 3D printing method than the CAD/CAM milling method. Therefore, the 3D printing method is considered as applicable for not only the interim restoration production, but also in the dental prosthesis production with a higher level of completion.

Development of an ISSR-Derived SCAR Marker in Korean Ginseng Cultivars (Panax ginseng C. A. Meyer)

Lee, Jei-Wan,Kim, Young-Chang,Jo, Ick-Hyun,Seo, A-Yeon,Lee, Jeong-Hoon,Kim, Ok-Tae,Hyun, Dong-Yun,Cha, Seon-Woo,Bang, Kyong-Hwan,Cho, Joon-Hyeong The Korean Society of Ginseng 2011 Journal of Ginseng Research Vol.35 No.1

Recently, new ginseng cultivars having superior agricultural traits have been developed in Korea. For newly developed plant cultivars, the identification of distinctiveness is very important factors not only in plant cultivar management but also in breeding programs. Thus, eighty-five inter simple sequence repeat (ISSR) primers were applied to detect polymorphisms among six major Korean ginseng cultivars and two foreign ginsengs. A total of 197 polymorphic bands with an average 5.8 polymorphic bands and 2.9 banding patterns per assay unit across six Korean ginseng cultivars and foreign ginsengs from 236 amplified ISSR loci with an average 6.9 loci per assay unit were generated by 34 out of 85 ISSR primers. Three species of Panax ginseng including the Korean ginseng cultivars, P. quinquefolius, and P. notoginseng, could be readily discriminated using most tested primers. UBC-821, UBC-868, and UBC-878 generated polymorphic bands among the six Korean ginseng cultivars, and could distinguish them from foreign ginsengs. Sequence characterized amplified region (SCAR) marker system was introduced in order to increase the reproducibility of the polymorphism. One SCAR marker, PgI821C650, was successfully converted from the randomly amplified polymorphism by UBC-821. It showed the expected dominant polymorphism among ginseng samples. In addition, the specific polymorphism for Sunwon was generated by treating Taq I restriction enzyme to polymerase chain reaction products of PgI821C650. These results will serve as useful DNA markers for identification of Korean ginseng, especially Sunwon cultivar, seed management, and molecular breeding program supplemented with marker-assisted selection.