Flangeless Esser PET Phantom 영상 자동 분석 프로그램의 유용성 평가

남궁창경,남기표,김경식,김정선,임기천,신상기,조시만,동경래,NamGung, Chang-Kyeong,Nam, Ki-Pyo,Kim, Kyeong-Sik,Kim, Jeong-Seon,Lim, Ki-Cheon,Shin, Sang-Ki,Cho, Shee-Man,Dong, Kyung-Rae 대한핵의학기술학회 2009 핵의학 기술 Vol.13 No.1

Purpose: ACR (American College of Radiology) offers variable parameters to PET/CT quality control by using ACR Phantom. ACR Phantom was made to evaluate parameters which are uniformity, attenuation, scatter, contrast and resolution. Manual analysis method wasn't good for the use of QC because values of parameter were changed as it may user and it takes long time to analysis. Ki-Chun Lim, a nuclear scientist in AMC, developed program that automatically analysis values of parameter by using ACR Phantom to overcome above problems. In this study, we evaluated automatic analysis program's usability, through the comparing SUV of each method, reproducibility of SUV when repeated analysis and the time required. Materials and Methods: Using Flangeless Esser PET Phantom, the ideal ratio of 4 : 1 hot cylinder and BKG but it actually showed a ratio of 3.89 to 1 hot cylinder and BKG. SIEMENS Biograph True Point 40 was used in this study. We obtained images using ACR phantom at Fusion WB PET Scan condition (2 min/bed) and 120 kV, 100 mAs CT condition. Using True X method, 3 iterations, 14 subsets, Gaussian filter, FWHM 4 mm and Zoom Factor 1.0, $168{\times}168$ image size. We obtained Max. & Min. SUV and SUV Mean values at Cylinder (8, 12, 16, 25 mm, Air, Bone, Water, BKG) by automatic program and obtained SUV by manual method. After that, we compared manual and automatic method. we estimate the time required from opened the image data to final work sheet was completed. Results: Automatic program always showed same result and same the time required. At 8, 12, 16 and 25 m cylinder, manual method showed 6.69, 3.46, 2.59, 1.24 CV values. The larger cylinder size became, the smaller CV became. In manual method, bone, air, water's CV were over 9.9 except BKG (2.32). Obtained CV of Mean SUV showed BKG was low (0.85) and bone was high (7.52). The time required was 45 second, 882 second respectably. Conclusions: As a result of difference automatic method and manual method, automatic method showed always same result, manual method showed that the smaller hot cylinders became, the lager CV became. Hot cylinders mean region size, the smaller hot cylinder size becomes we had some trouble in doing ROI poison setting. And it means increase in variation of SUV. The Study showed the time required of automatic method was shorten then manual method.

후두암의 보존적 수술에 대한 임상적 고찰

정경호,정상술,홍기환 釜算慶南耳鼻咽喉科學會 1994 임상이비인후과 Vol.5 No.1

5세 된 유전성 구상 적혈구증 환아에서 폐쇄성 황달을 동반한 다발성 담석증 1례

민택기,이인규,박경배,박준수 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Hereditary spherocytosis is a common cause of hemolysis and hemolytic anemia. Some children remain asymptomatic into adulthood but others may have severe anemia with pallor, jaundice and fatigue. After infancy, the spleen is usually enlarged, and pigmentary gallstones may form as early as age 4~5 year. But it increases abruptly after age 10 year. At least 50% of unsplenectomized patients ultimately form gallstones, although for the most part they remain asymptomatic. We report herewith a case of multiple gallstone with obstructive jaundice in 5 years old patient with hereditary spherocytosis.

음악적성검사 개발을 위한 기초연구

임충기,박경자 서원대학교 교육대학원 2000 교육논총 Vol.4 No.-

This was done to find optimal conditions of musical aptitude test as a preliminary study for developing such test. In this study. five considerations might be suggested as follows. First. an united concept about musical aptitude needs to be established through professional musician's theoretical judgements and empirical studies such as factor analysis. Second, test materials need to be adopted from musical context itself rather than from simple mechanical sounds. Also, it is necessary that test contents should include musical sensitivity and musical preferences Third. in developing musical aptitude tests, a paradigm needs to be changed from indirect measurement to direct measurement. Fourth, considerations on measurement characteristics such as reliability, validity, standardization should be emphasized. Fifth, it is necessary to develop our own musical aptitude test which is appropriate to our cultural background.

원위 전대뇌동맥류의 외과적 치료

성경훈,도종웅,강재규,김기욱 대한신경외과학회 1990 Journal of Korean neurosurgical society Vol.19 No.6

The authors described a more different type of aneurysms in the distal anterior cerebral artery (DACA), which is difficult to approach surgically. There are anomalies of distal anterior cerebral artery in about one fourth and narrow space, which made more careful surgical dissection. We experienced 7 cases of DACA aneurysm, 6 cases of which were treated surgically through the interhemispheric approach via the unilateral frontal paramedian craniotomy on the non-dominant side. Surgical results were anatomical complexities, modem microsurgical technique aided by microscope make the approach more exactly and safely.

석산폐석을 활용한 쇄석골재의 물리적 및 화학적 특성 연구

송기범,김경수 大田産業大學校 1996 한밭대학교 논문집 Vol.13 No.0201

골재의 수요는 매년 크게 중가하고 있으나 천연 골재는 점차 고갈되어 가고 있다. 따라서 기존석산들에서 발생되는 폐석자원을 쇄석골재로 활용하면 일거양득의 효과가 있다. 본 연구는 국내에서 가장 대규모 석산단지인 포천 및 익산지역 기존석산에서 발생되는 석산폐석에 대한 물리적, 화학적 및 광물학적 시험·분석을 실시하여, 쇄석골재로서 석산폐석의 특성규명과 활용가능성을 평가하였다. 연구결과, 포천과 익산지역에서 발생되는 석산폐석을 쇄석골재로 활용할 수 있을것으로 판단되었으며, 폐석자원을 쇄석골재로 활용함으로써 골재의 수요에 보충하고, 산림 및 자연경관의 훼손과 환경오염을 야기할 수 있는 석산골재 신규개발 의 억제에도 효과가 기대된다. The natural aggregate have been enormously consumed and eventually scarce due to the gradual growth of urbanization during the last several decades, a replacement of the conventional material being necessary. Such a replacement can be achieved by the utilization of quarry wastes. The annual quantity of the wastes produced in the Pocheon and Igsan areas, which are known as the biggest quarry sites in this country, was estimated and their quality was investigated as well, The quarry wastes collected from both of the areas were tested for their physical properties, chemistry and mineralogy in order to appraise their utilization potential as crushed aggregate. Based on all the test results, the wastes of the quarries in the Pocheon and Igsan areas May be utilized as crushed aggregate. It is expected that the quarry wastes will control the future development of quarry only for the production of aggregate which may give rise to the damage and pollution of natural environment.

학부모기로의 전환에 관한 연구

윤기영,이미경,박민자 서원대학교 교육연구소 2003 敎育發展 Vol.22 No.1

Parents experience a qualitative change in terms of relationship with their hildren when they start to attend the first educational institute. Parents' role as a 'Hakbumo', whose children are attending school, could be quite different from parents' general role at home. Therefore, it might be needed to investigate the 'Hakbumohood' transition process for appropriate parents development and home-institute relationship After the investigation of literature, in-depth interview and discussion was conducted with 7 early childhood education center 'hakbumo', 2 kindergarten teachers, 1 professor. The result of this study, 1) Most parents take they become a 'Hakbumo' as a matter of course. 2) They feel anxiety about their children's adaptation to new circumstances. 3) They feel variety feelings during the 'Hakbumohood' transition. 4) Their feelings and concern are different between pre attending institute and post attending 5) They were influenced wholeness environment So, it might be concluded that developing a individualized guidance and support program for each new ‘Hakbumo’

항 Vancomycin 내성균성 항생물질을 생산하는 Streptomyces sp.AMLK-335의 배양조건

이기형,임대석,최경희,이경호,김창한,김정환 건국대학교 동물자원연구센터 2000 動物資源硏究誌 Vol.21 No.-

본 연구는 새로운 항 vancomycin 내성균성 항생물질을 개발하기 위하여 실시되었으며, 전국 각지의 토양 시료로부터 분리한 방선균 중 vancomycin 내성균주인 K-98 Enterococcus faecium 642, K-98 Enterococcus faecium 637 균주에 대하여 항생물질을 생산하는 분리균주 AMLK-335를 선정하여 이 균주의 항생물질 생산에 대한 최적 발효 조건을 검토한 결과, 탄소원 첨가로는 glycerol(0.5%), 질소원 첨가로는 yeast extract(0.5%)가 가장 효과적으로 항생물질 생산에 이용되었고, 비타민을 첨가에 따른 항생물질 생산성의 차이는 크게 나타나지 않았으나, calcium pantothenate 첨가시 항균활성이 비교적 높아졌으며, 금속이온의 첨가는 K+, Pb+, Ba²+, NA²+ , Ca²+를 첨가하였을 때는 항생물질의 생산성이 비교적 높아졌으며, 그중 Ca²+ 첨가구가 가장 생산성이 높았으며, Fe²+ , Hg+의 금속이온을 첨가하였을 때는 항생물질 생산성이 감소하였으며, CaCO₃첨가는 비첨가구보다 높은 항생물질 생산성을 보였으나, 첨가량에 따른 영향은 대체적으로 없었다. pH의 변화에 따른 생산성은 전반적으로 pH가 항생 물질 생산에 영향을 미치지 못하였으나, pH 4.5∼6.0 부근에서는 비교적 높은 항생물질 생산성을보였으며, 통기량에 따른 항생물질 생산성은 통기량이 많을수록 항생물질 생산이 좋았다. 한편 배양기간에 따라 항생물질 생산성을 조사한 결과, 5일째에 가장 높은 항생물질 생산성을 나타내었으며, pH의 변화는 배양 초기에 하강하였다가 점차 상승하는 경향을 보였다. This study was carried out for examining antibiotic productivity of the strain Streptomyces sp. AMLK-335 producing anti-VRE antibiotic. According to different condition, the strain was cultured for 4 days at 27℃ and determined cell growth, pH value and antibiotic productivity using disk diffusion method. In the experiment, the strain Streptomyces sp. AMLK-335 was examined various culture conditions which was added 8 carbon sources, 12 nitrogen sources, 8 vitamins and 11 metal ions in each time and controlled concentration of CaCO₃, initial pH and aeration. From the studies of conditions for antibiotic production, antibiotic productivity was the best to use 0.5% glycerol as carbon source and 0.5% yeast extract as nitrogen source. When several vitamins were added to medium, there was little difference in antibiotic productivity. But the addition of calcium pantothenate slightly increased antimicrobial activity. The addition of metal ion, such as K+, Pb+, Ba²+, NA²+ and Ca²+ slightly increased antibiotic productivity except Fe²+ and Hg+. The addition of CaCo₃showed higher than non-addition experiment in antibiotic production, but there wasn't generally influenced at addition concentration. According to pH change, antibiotic productivity was increased at pH 4.5∼6.0, and when there was a lot of aeration, antibiotic productivity was increased.

논토양중 카드뮴 유효도와 수도의 흡수이행에 미치는 석회 및 Humic acid 사용효과

김민경,김원일,정구복,박광래,윤순강,엄기철 한국환경농학회 2004 한국환경농학회지 Vol.23 No.1

토양중 중금속이 식물에 흡수 및 이행되는 것을 경감시켜 여기에서 생산된 농산물의 안전성 향상을 위한 기초자료를 확보하고 논토양의 카드뮴 유효도와 흡수이행에 미치는 석회와 humic acid 처리 효과를 구명하기 위하여 실내경험과 포트실험을 수행하였다. 실내실험에서 공시토양에 2.5와 5.0 ton/ha의 석회와 1%와 2% humic acid를 처리한 후 토양중 가용성 카드뮴 함량 변화를 조사한 결과, 두 처리 모두 14일까지는 담수상태에서 처리효과로 인하여 가용성 카드뮴 함량이 감소하다가 그 이후에는 토양의 완충능에 의해 다시 증가하는 경향이었다. 이때, 토양의 가용성 카드뮴 함량은 토양 pH 및 양이온치환용량과 부의 상관이 있었다. 2.5 ton/ha의 석회와 1% 의 humic acid를 처리한 후 담수시켜 안정화된 다음 벼를 재배하여 조사한 결과, 석회와 humic acid 처리에 비해 분얼기와 수확기의 치화태 및 수용태 카드뮴 함량이 낮아졌으나, 분얼기에 비해 수확기에 토양중 이동이 어려운 산화물 및 탄산염태와 황화물 및 잔류태의 함량이 증가하였다. 식물에 흡수가 용이한 형태로 알려진 치환태와 수용태는 모두 토양 pH와 고도의 부의 상관이 있었다. 수확기의 줄기, 잎 및 현미 건물중은 석회 및 humic acide 처리구에서 대조구에 비해 모두 높았고, 특히 석회 처리구의 건물중이 현저하게 높았다. 석회 처리구에서 줄기와 잎의 카드뮴 함량은 각각 1.01과 0.37㎎/㎏으로 대조구와 비슷하였으나, 뿌리나 현미의 카드뮴 ?량은 각각 2.11과 0.09㎎/㎏으로 대조구에 비해 낮았다. 지상부와 뿌리의 카드뮴 함량은 humic acid 처리에 의해 현저히 낮아졌으며, 특히 현미로의 카드뮴 이행도 월등히 낮게 나타난다. This study was conducted to know the effect of lime and humic acid on cadmium availability and its uptake by plant grown in contaminated paddy soils with heavy metal. The treatment levels of lime were 2.5 and 5.0 ton/ha and that of humic acid were 1 and 2%. The contents of 0.1 N HCl extractable Cd were reduced with lime and humic acid and were negatively correlated with CEC as well as soil pH. The sequential extraction procedure was used to fractionate the heavy metals in soil into the designated from exchangeable (0.5 M KNO₃), water soluble (H₂O), organically bound (0.5 M NaOH), carbonate (0.05 M Na₂-EDTA) and sulfide/residual (4 M HNO₃). In soil amended with 2.5 ton/ha lime and 1% humic acid, chemical forms of Cd at tillering stage were predominant exchangeable+water soluble extractable Cd, whereas that at harvesting stage were predominant carbonate+sulfide/residual extractable Cd. The exchangeable forms of Cd in soil with lime and humic acid were negatively correlated with soil pH during the harvesting period. Total absorbed Cd of paddy rice tended to occur in the order of root > stem > leaf > brown rice. Cd con- tents of brown rice with lime and humic acid treatment were 0.09 and 0.08 mg/kg, respectively. That were lower than control, 0.20 ㎎/㎏. It could be that treatment of lime and humic acid in polluted soil by heavy metals would reduce the uptake of heavy metals by plants and be a temporary method of reclamation at the highly heavy metal contaminated soils.

어지러움의 이해

성기범,박선아,이태경 대한평형의학회 2002 Research in Vestibular Science Vol.1 No.2