Impacts and Countermeasures of Climate Change on Food Supply

Kim Chang-gil,Jeong Hak-kyun,Han Suk-ho,Kim Jeong-seung,Moon Dong-hyun 한국농촌경제연구원 2013 한국농촌경제연구원 기본연구보고서 Vol.- No.-

Climate change has become a megatrend that will lead to significant changes in future society. Korean and overseas agencies specializing in climate forecasts predict that average global temperatures will continue to rise. While climate change may potentially have certain positive impacts for crop yields, the overall impact is predicted to be negative for environment and food security. In this context, our study aims to suggest a plan for systematically establishing a stable food supply system in Korea in respose to climate change. Various analytical models were employed, including: a response analysis based on questionnaire for farmers, panel-based analysis of the causes of pests and diseases in rice production, a random-effects model for panel data of extreme weather impact, and an analysis of food supply effects using the Simulation Model for Climate-Agriculture Relations (SIMCAR) integrated model in conjunction with the Crop Estimation through Resource and Environment Synthesis (CERES) model of the Korea Agricultural Simulation Model (KASMO). An analysis was made of major grain yields by means of the KREI-KASMO. This revealed reduced yields and area in comparison with the baseline in 2050, resulting in a reduction of rice production by 17.8%p in the RCP8.5 scenario, and reduction of soybean by 21.2%p and reduction of barley by 13.7%p in the A2 scenario. Self-sufficiency ratio of major grains in 2050 drawn from the SIMCAR revealed that the climate change scenario for rice showed 55.0% to be reduced by 18.3% in comparison with the baseline. It is predicted that selfsufficiency ratio in rice will drop to 50% which means a half of consumed rice should be imported. Key tasks for building a stable food supply system to cope with climate change were developed based on the domestic production capacity, the buffering capacity to climate change, import capacity from other countries, and policy performance capacity with reference to the empirical analysis. First, the suggested key tasks for improving the domestic production capacity include developing and disseminating adaptation technology, conserving farmland and expanding arable land, practicing climate-smart agriculture by using fusion technology, and modernizing infrastructure for agriculture. Second, key tasks for improving buffering capacity to climate change are improving resilience and biodiversity, building a risk management system, and further improving storage of food in Korea and other countries. Third, major tasks for improving the import capacity from other countries are constructing overseas food bases, effectively using the international grain market, and enhancing international cooperation with relevant countries. Finally, key tasks for improving policy performance capacity are refining and applying the climate change impact analysis model with respect to policies, expanding investments in research and development, building a vulnerability assessment system, enhancing education and training, and installing Climate Change Response Center for Agriculture (tentative). In this study, several key challenges were presented in the four different areas related to building a stable food supply system which can help overcome the challenges of climate change. It is expected that the nature of the policies that need to be prioritized and promoted, given the constraints of budget, organization and information will be addressed in future research. Also, in order for the solutions for key challenges to work properly in the field such that policy outcomes will be maximized, a consortium of research bodies in the related fields of agriculture, agricultural meteorology and agricultural economics should be created. As preparation for specific action programs. Furthermore, follow-up studies should be conducted to verify the expenses required for developing reliable climate change impact assessment models and the effectiveness of the enforced policies. Such fie

白鼠 肝障碍에 對한 補肝湯 瀉肝湯의 效果에 關한 實驗的 硏究

洪茂昌,李學仁,金完熙 慶熙大學校韓醫科大學韓醫學硏究所 1983 慶熙韓醫大論文集 Vol.6 No.-

Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

TRANSIENT ISCHEMIA-INDUCED EXPRESSION AND CHANGES OF TYROSINE KINASE A IN THE HIPPOCAMPAL DENTATE GYRUS OF THE GERBIL

HWANG, IN,LEE, HYEON,YOO, KI-YEON,KIM, DAE,KIM, JUNG,KIM, CHANG,LIM, BEONG,KANG, TAE-CHEON,BANG, KYUNG,SEONG, NAK,LEE, HAK,KIM, JONG,WON, MOO Taylor Francis 2006 International journal of neuroscience Vol.116 No.8

<P>The present study examined ischemia-related changes in tyrosine kinase A (trkA) immunoreactivity and its protein content in the dentate gyrus after 5 min of transient forebrain ischemia in gerbils. One day after ischemic insult, cresyl violet-positive polymorphic cells showed ischemic degeneration. The ischemia-induced changes in trkA immunoreactivity were found in the polymorphic layer (PL) and granule cell layer (GCL) of the dentate gyrus. In the sham-operated group, trkA immunoreactivity in the dentate gyrus was very weak. From 30 min after ischemia, trkA immunoreactivity was increased in the dentate gyrus and peaked in the dentate gyrus at 12 h after ischemia-reperfusion. Thereafter, trkA immunoreactivity was decreased time-dependently after ischemia-reperfusion. Four days after ischemic insult, trkA immunoreactivity was similar to that of the sham-operated group. In addition, it was found that ischemia-related changes in trkA protein content were similar to the immunohistochemical changes. These results suggest that the chronological changes of trkA in the dentate gyrus after transient forebrain ischemia may be associated with ischemic damage in polymorphic cells of the dentate gyrus.</P>

Uncoupler를 투여한 흰쥐의 뇌와 간조직의 Superoxide Dismutase에 관한 연구

오창학,이동욱,이희성 중앙대학교 의과대학 의과학연구소 1985 中央醫大誌 Vol.10 No.3

The activities of superoxide dismutases, and the variation of superoxide radicals and hydrogen peroxide contents in the brain and liver tissues, and some of the classic signs of rats administered with either 2, 4-dinitrophenol or arsenate has been investigated. Superoxide dismutase activities were determined either by the method of McCord and Fridovich(1969) or by the method of Crapo et al, (1978). The contents of hydrogen peroxide was determined according to the method of Thruman et al, (1972). The experimental results were summarized as follows; 1. Body weights of animals administered with 2, 4-dinitrophenol and/or arsenate were decreased, but the rectal temperatures of animals treated rose above the normal when compared with those of control group. 2. Formation of superoxide radicals in the tissues of brain and liver of 2, 4-dinitrophenol treated animals was increased to each 1.5 and 1.3 times those of the control group. However, formation of superoxide radicals in the tissues of animals administered with arsenate was not changed in the brain tissues, but significantly decreased in the liver tissues. 3. The contents of hydrogen peroxide was slightly increased in both brain and liver tissues of animals administered with 2, 4-dinitrophenol, but no changes occured in those tissues of animals administered with arsenate. 4. The specific activity of total superoxide dismutase in the brain tissues of animals administered with 2,4-dinitrophenol was enhanced up to 1.7 times that of the control group, but when treated with arsenate, the specific activity was closed to that of the control group. 5. The specific activities of total superoxide dismutase in the liver tissues of animals treated with 2,4-dinitrophenol and/or arsenate were 4.68 and 3.77, respectively. 6. The activities of Mn-superoxide dismutase in the brain and liver tissues of animals treated with 2,4-dinitrophenol was increased to 2.2 and 2.0 times as higher as that of the control group, but no significant change in the activity of Cu,Zn-superoxide dismutase was observed, whereas in the case of arsenate treated animals, no changes in the specific activities of Cu,Zn- and Mn-superoxide dismutase was observed. These results indicated that an uncoupler 2,4-dinitrophenol which may act on all the sites of oxidative phosphorylation caused to increase the superoxide radicals in the cells, and this might occur at State 4. A parallel increment of the formation of superoxide radicals and Mn-superoxide dismutase activities would suggest that the enzyme, especially Mn-superoxide dismutase, must be an important factor to protect the mitochondria from the toxicity by superoxide radicals.

출산에 따른 그레이브스병의 재발 및 관련이자

임창훈,최현아,한승석,김해성,이창욱,정호연,한기옥,장학철,박원근,윤현구,한인권 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.2

Background: Pregnancy affects the course of Graves' Disease (GD), and patients who initially maintain euthyroid function into their middle trimester with minimum doses of antithyroid drugs become exacerbated after delivery. Even patients who are completely cured, requiring no treatment during pregnancy, can relapse after delivery. In this study, we examined the postpartum changes in the thyroid functions of patients with GD, and attempted to determine the factors contributing to these changes. Methods: The study subjects were recruited from pregnant women visiting our outpatient clinic for routine prenatal evaluations. 45 women previously diagnosed with GD, who had been treated and cured with hyperthyroidism, and were no longer taking any thyroid medications, were evaluated for 1 year post delivery. Results: Among 45 patients, 20 (44.4%) developed thyroid disorders following delivery. Postpartum thyroiditis (PPT) developed in 8 patients (17.8%), and GD developed in 12 (26.0%). The onset of the PPT disease 3.1 ± 1.4 months following delivery, which was significantly earlier than the 6.7 ± 2.7 months required for the post delivery onset of GD (p=0.003). The TBII values, measured during the thyrotoxic state in each womaen, were negative in women with PPT and positive in 71.4% of women with GD (p=0.030). The duration of treatment for hyperthyroidism prior or pregnancy, the number of recurrences, and the time interval without treatment, were not associated with the development of postpartum thyroid disorders. Whereas, the mean number of past pregnancies for women who developed PPT was 3.9 ± 2.1, and was significantly higher than the 2.2 ± 1.7 for women developing no thyroid dysfunctions (p=0.044). In 13 women their initial onset of GD occurred within one year postpartum, 7 (53.8%) having had a recurrence, which was significantly higher than in women whose disease onset occurred unrelated to delivery (5 of 32 women: 15.6%). Conclusion: Women with GD developed postpartum thyroid dysfunctions in 44.4% of cases. Women whose initial disease onset occurred within one year postpartum had higher recurrences of GD, and women who developed PPT had a history of higher gravidity compared to the euthyroid women postpartum. Therefore, if women with GD develop postpartum thyroid dysfunctions, the diagnosis should be made, and a treatment modality planned, following careful considerations of the patients' past obstetric history, changes in clinical manifestations and the TBII values

Ischemia-Related Changes in Galanin Expression in the Dentate Hilar Region after Transient Forebrain Ischemia in Gerbils

LEE, Hyeon Yong,HWANG, In Koo,KIM, Dae Ho,KIM, Jung Hwa,KIM, Chang Ho,LIM, Beong Ou,KANG, Tae-Cheon,BANG, Kyung Hwan,SEONG, Nak Sul,LEE, Hak Ju,KIM, Jong Dai,WON, Moo Ho Japanese Association for Laboratory Animal Science 2005 EXPERIMENTAL ANIMALS Vol.54 No.1

<P>Although galanin (GAL) protects hippocampal neurons from ischemic damage, no study has examined ischemia-related changes in endogenous GAL in the hippocampal dentate gyrus. We investigated the chronological changes of GAL, well-known as the potassium channel opener, expression in the dentate gyrus at various times after 5 min of transient forebrain ischemia in gerbils. A few GAL-immunoreactive (IR) neurons were found in the polymorphic layer of the sham-operated group. Three hours after ischemia-reperfusion, the pattern of GAL immunoreactivity was similar to that of the sham-operated group and the number of GAL-IR neurons and immunoreactivity were highest 12 h after ischemic insult. At this time, GAL-IR neurons in the polymorphic layer showed strong GAL immunoreactivity. Thereafter, GAL-IR neurons and immunoreactivity significantly decreased in the dentate hilar region. Four days after ischemic insult, GAL-IR neurons were not detectable. In addition, the results of a Western blot study showed a pattern of GAL expression similar to the immunohistochemical changes. GAL protein content also was highest 12 h after ischemia. In conclusion, the increased expression of endogenous GAL in the dentate gyrus after ischemia is related to response to the ischemic damage.</P>

Study on the Fire Hazard and Risk Analysis Derived from the Plant Configuration Change During the Shutdown Period at Nuclear Power Plants

Jee Moon-Hak,Hong Sung-Yull,Sung Chang-Kyung,Jung Hyun-Jong Korean Nuclear Society 2003 Nuclear Engineering and Technology Vol.35 No.6

Fire hazard and risk analysis at Nuclear Power Plants is implemented on the basis of the normal operational configuration. This steady configuration, however, can be changed due to the temporary displacement of equipment, electric cable and irregular movement of workers through the fire compartments when the on-line maintenance is processed during the power operation mode or the scheduled outage mode for the refueling. With the consequence of this configuration change, the fire analysis condition and the evaluation result will be different from those that were analyzed based on the steady configuration. In this context, at this paper, the general items for the reassessment are categorized when the configuration has changed. The contemporary zone models for the detail fire analysis are also illustrated for their application for each classified condition.

Calculation of GHGs Emission from LULUCF-Cropland Sector in South Korea

Seong-Jin Park,Chang-Hoon Lee,Myung-Sook Kim,Sun-Gang Yun,Yoo-Hak Kim,Byong-Gu Ko 한국토양비료학회 2016 한국토양비료학회지 Vol.49 No.6

The land use, land-use change, and forestry (LULUCF) is one of the greenhouse gas inventory sectors that cover emission and removals of greenhouse gases resulting from land use such as agricultural activities and land use change. Particularly, LULUCF-Cropland sector consists of carbon stock changes in soil, N₂O emissions from disturbance associated with land use conversion to cropland, and CO₂ emission from agricultural lime application. In this paper, we conducted the study to calculate the greenhouse gases emission of LULUCFCropland sector in South Korea from 1990 to 2014. The emission by carbon stock changes, conversion to cropland and lime application in 2014 was 4424, 32, and 125 Gg CO₂-eq, respectively. Total emission from the LULUCF- Cropland sector in 2014 was 4,582 Gg CO₂-eq, increased by 508% since 1990 and decreased by 0.7% compared to the previous year. Total emission from this sector showed that the largest sink was the soil carbon and its increase trend in total emission in recent years was largely due to loss of cropland area.

악안면 성장예측 모형개발에 관한 연구 : 6세 어린이의 1년간 악안면성장에 관한 연구

김종배,문혁수,장영일,배광학 대한구강보건학회 1999 大韓口腔保健學會誌 Vol.23 No.2

The purpose of this study was to obtain the data on the maxillofacial growth changes of the Korean six-year-old children in a year to establish the maxillofacial growth prediction model. Dental arch stone models of the 682 students in 1995 and of the same students in 1996 were analysed. The maxillofacial growth changes of the students during one year were found by the analysing the dental arch stone models. The dental arch growth changes in a year were analysed by student t-test and the qunantity of growth per a year of dental arch lengths and widths by paired t-test. The obtained results were as follows: 1. It was found that all dental arch lengths and widths had grown during one year. 2. There is no difference between male and female students in maxillofacial growth changes. 3. Maxilla had grown a little more than Mandible during one year. 4. Dental arch lengths had grown a little more than dental arch widths during one year.