CHARACTERISTIC POLYNOMIALS OF SOME WEIGHTED GRAPH BUNDLES AND ITS APPLICATION TO LINKS

Sohn, Moo-Young,Lee, Ja-Eun 國立 昌原大學校 基礎科學硏究所 1994 基礎科學硏究所論文集 Vol.6 No.-

In this paper, we introduce weighted graph bundles and study their characteristic polynomial. In particular, we show that the characteristic polynomial of a weighted K_(2) (??_(2)) bundles over a weighted graph Γ_(ω) can be expressed as a product of characteristic polynomials two weighted graphs whose underlying graphs are Γ As an application, we compute the signature of a link whose corresponding weighted graph is a double covering of that of a given link.

갑상선 유두암이 병발된 가족성 대장 용종증 1예

백종현,소창배,이은영,이지숙,신은경,박은호,서정아,양재홍,송준영,박선자,박요한,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome, typically characterized by multiple colorectal adenomas and increased incidence of colorectal carcinomas if it is not treated. Moreover, a variety of extracolonic manifestation are seen. The prevalence of thyroid tumors developing in patients with FAP is about 1∼2%. Generally, papillary thyroid cancer indicates low mortality but ,however, as people get older, the cancer becomes more aggressive. So, the operation is required. Recently we experienced a case of FAP, presenting with papillary thyroid carcinoma, and reported with a brief review of literatures.

일측 시상경색 후 발생한 기억장애 2예

순은희,이애영,김선국 대한치매학회 2002 Dementia and Neurocognitive Disorders Vol.1 No.1

Lesions of the anterior and medial parts of the thalamus are often accompanied by memory dysfunction Bilateral lesions may produce major memory deficits that have sometimes been reported to last for several years Unilateral lesion may also be associated with memory dysfunction which is usually less severe and persistent and may be linked to a selective field of memory We report two amnesic patients with isolated infarct in the polar territory of the left thalamus. This cases demonstrate that unilateral left thalamic infarction in the polar territory can be presented with isolated verbal amnesia with relatively preserved visuospatial memory function and lateralization of memory dysfunction after thalamic infarction which is not always present.

일차성 식도이완불능증의 풍선확장술후 치료효과의 객관적 평가지표

손영해,나호영,조성범,주영은,김현수,최성규,유종선,김세종 全南大醫大 2001 전남의대학술지 Vol.37 No.2

서울 북부지역의 생활폐기물 발생량 및 조성 분석

손종렬,배은상,김영환,문경환 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

This study was carried out to investigate on the generation and composition of municipal waste in north area of Seoul. The results was as follows: 1. The generation and composition of municipal waste was investigated foods> papers> glasses> plastics> metals(cans)> textiles> leaches> woods> ashes> rubbers> ceramics> leathers in residential area, that was investigated papers> foods> plastics> glasses(bottles)> textiles> metals> ashes> leaches> rubbers> ceramics> leathers in nonresidential area. 2. The recycling generation of municipal waste was investigated papers> glasses> plastics> metals> textiles> woods in residential and nonresidential areas. 3. The three components(water, combustion & ash) was analysed in each composition of municipal waste for the deciding treatment methods of waste in residential and nonresidential areas. The water component of each composition was analysed foods> papers> woods> textiles> rubbers > ashes in residential area, which analysed foods> papers> ashes> woods> textiles> rubbers in nonresidential area. The combustible component was analysed plastics> textiles> woods> rubbers>papers in residential and nonresidential area. The ash component was analysed nonferrous metals> ferrous metals> ceramics> ashes in residential area, that was analysed ceramics> ferrous metals> nonferrous metals> ashes in nonresidential area. Conclusively, in order to treat municipal waste the separated collection system should be systematically performed, the next improvable proposal of the detailed methods should be prepared.

알쯔하이머병 환자의 혈소판 아밀로이드 전구단백질 이상

이애영,조은경,김건익,김선국,손은희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Background:Although Alzheimer's disease (AD) is a progressive neurodegenerative disorder without any truly effective pharmacological treatment at present, early accurate diagnosis is important for the delaying of disease progression and proper management It would be desirable to have a peripheral biological marker to identify patients affected by AD Amyloid β-peptide originates from a larger precursor, the amyloid precursor protein (APP). which can be seen in the platelet of its equivalent to those found in brain. To investigate if there is a correlation between level of platelet APP isoform and AD, we evaluate a cohort of subjects including patients affected by sporadic AD, vascular dementia, and controls Subjects & Methods :Thirty-five patients with sporadic AD diagnosed according to the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Relatec Disorders criteria (NINCDS-ADRDA) and 26 vascular dementia patients diagnosed by the Diagnosis and Statistical Manual of Mental Disorders, Fouth Edition (DSM-Ⅳ) criteria and 12 controls were included Blood sample were drawn from fasting state and collected into 3 mL of 3.8% sodium citrate. Platelets were collected by centrifugation at 500 g for 20 minutes and washed. and the platelet pellet was stored at -80℃ until used APP was assessed by western blot analysis and quantified by densitometry using Image Analyzer Results:In platelets densitometer as well as the result of Western blot was higher compared with those of patients with non-Alzheimer dementia and controls We observed statistically significant reductions in the ratio of 120 kDa to 130 kDa APP to 110 kDa APP (APPr) for patients with probable AD compared with control subjects and patients with vascular dementia APPr levels in AD correlated with the severity of dementia measured by CDR. Accuracy levels measured by Receiver Operating Curve analysis showed that a cut-off level of 0.45 resulted in a sensitivity of 71% and a specificity of 74%, with an area under the curve of 0 793 Conclusion:Platelet APPr allowed to differentiate AD from normal aging and vascular dementia with high sensitivity and specificity These findings suggest that platelet APPr may be a helpful peripheral marker for diagnosis and clinical progression of Alzheimer disease.

Naltrexone으로 전처치된 사회적 음주자에서 음주 유발 후 음주 갈망과 혈장 β-endorphin의 변화

김은희,손인기,이영식,나철 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: Opioid 길항제인 날트렉손은 알코올리즘 환자와 정상인의 음주행위에 영향을 준다는 보고가 있다. 그러나 날트렉손의 임상효과에 대한 기전은 아직 명확하지 않다. 이에 저자들은 사회적 음주자에서 날트렉 손의 임상효과 여부와 그 작용기전을 규명하고자 하였다. 방법: 사회적 음주자 15명을 대상으로 날트렉손을 이중맹검, 교차, 위약대조법으로 1주일간 전처치한 후, 음주 유발 검사를 통하여 알코올의 정신신테반응, 음주에 대한 갈망욕구와 혈장 β-endorphin과 ACTH, 혈청 cortisol 농도의 변화를 비교하였다. 결과: 1) NTX 전처치시 위약 전처치시보다 두통, 어지러움, 예민해짐, 피곤함, 주간 중 졸리움, 오심, 식욕감소 등의 부작용을 더 많이 경험하였으며(p<0.05), 혈청 GOT/GPT에 대한 영향은 차이가 없었다. 2) NTX 전처치시 음주갈망은 위약 전처치시와 비교하여 음주 전에는 차이가 없었으나, 음주 후 20분과 60분에서는 NTX 전처치시 음주갈망이 위약 전처치시 음주갈망 보다 유의하게 낮았다(p<0.05). 3) NTX 전처치시 어지러움증은 음주후 20분 뒤에는 두드러지지 않지만, 음주후 60분이 경과시에는 유의하게 높았고(p<0.05), NTX 전처치시에 음주 후 기타 신체적 불편감을 더 많이 호소하였으나 통계적인 의미는 없었다. 위약 전처치시 NTX 전처치시보다 기분이 상승되는 경향을 보였지만 통계적 의의는 없었다. 4) 음주 직전을 기준으로 한 음주 후 20분에서 혈장 β-endorphin 농도 변화율은 NTX 전처치시에 위약 전처치시보다 유의하게 증가하였다(p<0.05). 그러나 음주 직적을 기준으로 한 음주 후 60분에서 혈장 β-endorphin 농도변화율은 차이를 보이지 않았다. 5) 음주 직전을 기준으로 한 음주 후 20분에서 혈장 ACTH 농도 변화율은 NTX 전처치시에 위약 전처치시보다 유의하게 적은 감소율을 보였다(p<0.05). 그러나 음주 직전을 기준으로 한 음주 후 60분에서 혈장 β-endorphin 농도변화율은 차이를 보이지 않았다. 6) 음주 직전을 기준으로 한 음주 후 결정 cortisol 농도 변화율은 NTX 전처치시와 cortisol 전처치시에 차이가 없었다. 결론: NTX는 사회적 음주자에서 음주갈망의 감소를 야기하며, 이는 NTX의 신체적, 심리적 불편감 등의 간접적 결과하기 보다는 NTX의 opioid 긍정 강화체계에 대한 차단작용과 NTX의 알코올 유사효과라 여겨진다. Objectives: The present study was performed to evaluate whether naltrexone treatment are effectively lowering the urge of alcohol drinking, and to investigate the its mechanism of action. Methods: 15 healthy mals social drinkers were voluntarily participated. The experimental method was double-blind placebo-controlled cross over design. Subjects ingested a naltrexone (50mg)/day or placebo for 1 week. Plasma β-endorphin, plasma ACTH and serum cortisol levels were measured before, at 20 minutes and at 60 minutes after alcohol exposure. Subjects completed self-report questionnaires such as the visual analog scales of drink urge and the alcohol sensation scales at regular intervals. Results: 1) During naltrexone pretreatment period, subjects reported more headache, dizziness, nere-ousness, fatigue, day somnolence, nausea, and decreased appetite than placebo pretreatment period. But serum GOT/GPT levels were not significantly different between two pretreatment periods. 2) In case of naltrexone pretreatment, subjects reported significantly less urge to alcohol drink on the self-reporting urge scales, especially at post-drinking 20 minutes and 60 minutes than placebo pretreatment. 3) After alcohol challenge, subjects reported significantly more dizziness on the alcohol sensation scales in case of naltrexone pretreatment, and reported less mood elevation trend though it was not statistically significant. Other scores were not significantly different between two pretreatments. 4) Plasma β-endorphin levels were significantly different when treated with naltrexone. In case of naltrexone-pretreatment, the increasing degree of plasma β-endorphin during 20 minutes after alcohol challenge was significantly higher than placebo pretreatment. 5) Basal plasma ACTH level and basal serum cortiso level were not significantly different between two pretreatments. After alcohol challenge, only the decreasing degree of plasma ACTh levels during 20 minutes was significantly lowered in the naltrexone pretreatment than placebo pretreatment. Conclusion: Naltrexone reduced urge to alcohol drinking in social drinker. The action mechanism of naltrexone may be partially blocking opioid positive reward system and partally alcohol mimicking its property.

高果糖 誘導 고지혈증 흰쥐에 대한 薏苡仁의 효과

이영종,손영종,임덕빈,이은섭,박중수,김성기 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1

Objective : In order to examine the effects of Coicis Semen on the hyperlipidemia, the extracts of Job's Tears were given to hyperlipidemic rats induced by fructose-rich chow. Method : The hyperlipidea was induced by fructose-rich chow during five weeks in rats. And the rats were administered with the extracts prepared from husk layer, bran layer, polished rice, unpolished rice or unhulled grain of Job's Tears each others during three weeks. And then, the effects of the extracts on body weight gain, total cholesterol, triglyceride and blood glucose were examined. Results and Conclusion : The extracts prepared from polished rice, unpolished rice or unhulled grain of Job's Tears had no effects on the body weight gains of the corpulent rats induced by a high fructose diet. Meanwhile, the extracts prepared from the unhulled grain (Coicis Semen), unpolished rice, and bran layer of Job's Tears decreased the levels of blood total cholesterol. and triglyceride, each others. And the effect of unhulled grain was more stronger than those of the others. The results suggested that unhulled grain had some materials useful for alleviating the hyperlipidemia, and the effective molecule is existed in the surface of unhulled grain.

노년여성의 브래지어 착용실태 조사연구

박은미,김영숙,손희순 服飾文化學會 1996 服飾文化硏究 Vol.4 No.2

The purpose of this study is to suggest fundamental information about wearing method and production of brassiere, which is suitable for physiological hygiene and efficient action for elderly women. The subject is 418 elderly women aged 50~69 years old. Data is processed by a computer(SAS) and is analyzed by using frequency, percentage, χ²-test. The main results of this study are as follows: 1. Elderly women' weight and breast size are higher than their younger counterparts' in their 20's. but the older and poorer women with more children have smaller weight and breast. Most of the elderly women feel that their breasts are drooped or falling apart. In fact, those elderly women who gave birth to more children have more drooped and wider breasts. the major type of elderly women' breasts is the drooped breast' featured by those elderly women who have more children. 2. Most of the elderly women began to wear the brassiere for the first time in their 20's. the older women with more children began to were the brassiere earlier, while those less educated and poorer began to protect their breasts with brassiere later. Many elderly women were the brassiere to be protected from dirt, noise or look more neat, but day tend to wear the brassiere not all day around but at certain times, older, less educated and poorer women with more children tend to use the brassiere for etiquette and less often. This group of elderly women feel tedious, strange or uncomfortable for the brassiere. 3. Most of the elderly women know about their brassiere size. Such variables as age, education and income are correlated positively with the interest in and conscious ness of the brassiere size. All in all, the statistical distribution of elderly women's brassiere size is very wide, while most of them use 90A, 85A and 95A sizes. On the other hand, the most popular size for the under bust circumference is 85~90cm, while their primary cup size is A.

FET형 CO₂센서의 제조 및 감응특성

이은숙,이영철,정지영,윤종훈,김창수,손병기,이흥락 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

A FET type micro CO_(2) sensor based on a Severinghaus type arrangement has been prepared and its response characteristics were examined. The sensor was fabricated by formation of hydrogel layer containing bicarbonate/chloride ions on the PH-ISFET and the Ag/AgCl reference electrode prepared by the thermal evaporation and chemical chloridation methods. And then gas-permeable membrane was dip-coated on the hydrogel layer of the sensor. Gas-permeable membranes were fabricated with silicon rubber and polyurethane dissolved in toluene and THF, respectively. The CO_(2) sensor with the silicon rubber membrane showed better sensitivity and lower detection limit than the CO_(2) sensor with the polyurethane membrane for dissolved CO_(2). The sensor with silicon rubber membrane at optimal conditions showed a good response: linear range of 1.60X10^(-4) ~ 4.40X10^(-2) M CO_(2), sensitivity of 57.30 mV/decade, and detection limit of 7.50x10^(-4) M.