고등학생의 인터넷 사용정도와 학교적응, 친구관계에 대한 연구

이현주,김미연,이희재,권소영,김민정,김민주,방은혜,이경희,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38

Today, almost all families are quipped with computers. At the same time, we can find lots of side-effects because of computers. If young students, who tend to be unable to control their impulses once they are immersed in internet, the problem will be more serious. It could be happened that the young students can't distinguish the real from the image. Therefore, it is important to grasp the actual condition of juvenile Internet addicts and their practical life, and to come up with basic materials necessary for working out countermeasures. This study surveyed 339 high school students from three high schools in the area of Seoul. Data collection were collected from 22nd of December, 2003 to 27th of December 2003. The collected data were analyzed by SPSS program using T-test, ANAVA and Pearson correlation coefficient. The results were as follows: First, of the 333 respondents 9.61% of them were high-risk internet using group, 15.02% of them were potential-risk internet using group. 25% of then were identified as addicted group. Second, the more addicted the subjects are, the lower their level of school adjustment becomes. For the addicted group, it is difficult to adjust their school and to have a good relationship with friend. Third, the more addicted the subjects are, the lower their level of friendship becomes. The subordinate areas of friendship have same results as the level of Internet addiction and the extent of friendship. If students are addicted to Internet, it is difficult to find friends who can give them encouragement in practical life. Firth, there was a negative relationship between Internet addiction and school adjustment, and, there was a negative relationship between Internet addiction and friendship. Through this study we have seized the relationship between Internet addiction and school adjustment and friendship. As a result, the more addicted, the more difficult to adjust to school. And for the students who were addicted, it is difficult to make a friend.

미세혈관 협심증 환자의 임상상 및 지표에 관한 연구

박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.

Poster Session 2 : Developmental Biology ; Effects of hair follicle dermal sheath cells in the reconstruction of skin equivalents

( Hyun Joo Cho ),( In Hwa Bae ),( Hyun Joo Chung ),( Dong Seok Kim ),( Sun Bang Kwon ),( Young Joon Cho ),( Sang Woong Youn ),( Kyoung Chan Park ) 한국생화학분자생물학회 (구 한국생화학회) 2004 생화학분자생물학회 춘계학술발표논문집 Vol.2004 No.-

Effects of Dermal Fibroblasts and Dermal Sheath Cells in the Reconstruction of Skin Equivalents

( Hyun Joo Cho ),( In Hwa Bae ),( Hyun Joo Chung ),( Sun Bang Kwon ),( Kyoung Chan Park ) 대한피부과학회 2003 초록집 Vol.41 No.20

Development and Validation of a Novel Difficulty Scoring System for Liver Re-resection for Hepatocellular Carcinoma with Previous Hepatectomy

Joo Hyun Bang,Jai Young Cho,Ho-Seong Han,Yoo-Seok Yoon,Hae won Lee,Boram Lee,Yeshong Park,Jinju Kim,MeeYoung Kang,Eunhye Lee 대한외과학회 2023 대한외과학회 학술대회 초록집 Vol.2023 No.5

The Synergism between Belotecan and Cisplatin in Gastric Cancer

Joo Young Jung,Sang Hyun Song,Tae-Young Kim,Jung Hyun Park,Hyun-Soon Jong,Seock-Ah Im,Tae-You Kim,Yung-Jue Bang,Noe Kyoung Kim 대한암학회 2006 Cancer Research and Treatment Vol.38 No.3

Purpose: We wanted to demonstrate the anti-cancer effect and interaction between belotecan and cisplatin on gastric cancer cell line and we evaluated the mechanisms of this synergistic effect in vitro. Materials and Methods: The growth inhibitory effect of belotocan and cisplatin against several gastric cancer cell lines (SNU-5, SNU-16 and SNU-601) was estimated by tetrazolium dye assay. The effect of a combination treatment was evaluated by the isobologram method. The biochemical mechanisms for the interaction between the drugs were analyzed by measuring the formation of DNA interstrand cross-links (ICLs) and DNA topo-I activity.Results: Belotecan showed synergism with cisplatin for growth inhibitory effect on the gastric cancer cell lines SNU-5, and SNU-16, but this was subadditive on the SNU- 601 cell line. The formation of DNA ICLs in SNU-16 cells by cisplatin was increased by combination with belotecan, but this was not affected in SNU-601 cells. The topo-I inhibition by belotecan was enhanced at high concentrations of cisplatin in SNU-16, but not in SNU-601 cells.Conclusion: Belotecan and cisplatin show various combination effect against gastric cancer cells. The synergism between cisplatin and belotecan could be the result of one of the following mechanisms: the modulating effect of belotecan on the repair of cisplatin-induced DNA adducts and the enhancing effect of cisplatin on the belotecan-induced topo-I inhibitory effect. (Cancer Res Treat. 2006;38:159-167)

The Reconstruction of Skin Equivalents with Hair Follicle Dermal Sheath Cells

( Hyun Joo Cho ),( Hye Ryung Choi ),( In Hwa Bae ),( Hyun Joo Chung ),( Dong Seok Kim ),( Sun Bang Kwon ),( Jung Im Na ),( Sang Woong Youn ),( Kyoung Chan Park ) 한국조직공학과 재생의학회 2004 조직공학과 재생의학 Vol.1 No.2

The skin consists of two main layers, the epidermis and dermis, which are separated by the basement membrane. Epidermal-dermal communication is important for skin homeostasis, and dermal factors play a key role in regulating the growth and differentiation of the epidermis. Several studies have demonstrated that hair follicle dermal sheath cells (DSCs) synthesize more soluble factors than dermal fibroblasts. The aim of this study is to investigate the effects of DSCs upon the evolution of skin equivalents (SEs). In this study, human keratinocytes were seeded on two different dermal substitutes. In addition, the effects of ascorbic acid were evaluated. Histologically, thick epidermis was observed in DSC-derived models. Immunohistochemical staining showed similar pattern of involucrin in both DSC- and fibroblast-derived models, but filaggrin was expressed much stronger in DSC models. The number of PCNA positive cells was lower in the DSC model than in the fibroblast model especially in the presence of ascorbic acid. However, integrin a6 was strongly expressed in DSC models and in the presence of ascorbic acid supplementation. These findings suggest that DSCs secrete or synthesize factors, which affect the epidermalization of the skin, and that ascorbic acid is an important supplement in the reconstruction of human epidermis. In addition, transmission electron microscopy of SEs was performed and a well-developed intercellular junction was observed in the DSC models. Our results suggest that dermal compartment-related epidermis modifications are important in the processes of differentiation and proliferation in SEs.

Frontal Sinus Osteoplastic Flap Surgery Using a Surgical Navigation System

Bang, Yu Jin,Lim, Byeong Woo,Ha, Ryun,Woo, Joo Hyun,Kim, Seon Tae,Jung, Joo Hyun,Cha, Heung Eog,Chang, Jin Soon,Han, Ji Hye,Choi, Ji Yun,Kang, Il Gyu by Mutaz B. Habal, MD. 2018 JOURNAL OF CRANIOFACIAL SURGERY - Vol.29 No.7

OBJECTIVE:: To report the case of a 38-year-old woman who underwent osteoplastic flap surgery for recurrent frontal sinus mucocele. During surgery, the exact shape of the frontal sinus was duplicated using a surgical navigation system. METHODS:: In this case report, the authors suggest intraoperative surgical navigation systems are useful for accurately determining the dimensions of the frontal sinus for osteoplastic flap surgery. RESULTS:: The patient underwent successful and safe osteoplastic flap surgery using a surgical navigation system. CONCLUSION:: Surgical navigation is useful and safe for frontal sinus osteoplastic flap surgery.

Geriatric functional assessment for decisionmaking on adjuvant chemotherapy in older colon cancer patients

Hyun Jin Bang,Hyun Jeong Shim,Ga Ram Kim,Jun Eul Hwang,Woo Kyun Bae,Ik Joo Chung,Sang Hee Cho 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.3

Background/Aims: Despite the increasing need for geriatric assessment prior to chemotherapy, the method for this assessment remains inadequate for older cancer patients. We aimed to propose a simple assessment method to predict the performance of adjuvant chemotherapy in older patients after colon cancer surgery. Methods: This prospective study included patients over 65 years of age who were scheduled for adjuvant chemotherapy after colon cancer surgery. Before initiating chemotherapy, their functional status was assessed on the basis of activities of daily living (ADL)/instrumental activities of daily living (IADL). These parameters were analyzed with clinical characteristics and the patterns of adjuvant chemotherapy. The focus was on the completion rate of adjuvant chemotherapy. Results: A total of 89 patients with a median age of 72 years were analyzed. Among them, 54 (61%) were non-impaired and 35 (39%) were impaired regarding their ADL/IADL classification. Low body mass index and impairment of ADL/IADLs were significantly associated with chemotherapy interruption. Among toxicities, fatigue and hand-foot syndrome were independent prognostic factors for chemotherapy interruption. Impairments of ADL/IADL were significantly associated with fatigue regardless of age. Based on age and ADL/IADL stratification, younger patients (≤ 72 years) and/or those who were ADL/IADL non-impaired were significantly more likely to complete adjuvant chemotherapy than older patients (> 72 years) and ADL/IADL impaired patients (p = 0.038). This was regardless of the chemotherapy regimen. Conclusions: Functional assessment using ADL/IADL is a convenient method to predict chemotherapy toxicity and performance. These results suggested that routine screening for ADL/IADLs could guide appropriate patient selection for the completion of adjuvant chemotherapy and predict expected outcomes.

한국철학 : 「천명도天命圖」의 판본문제 고찰- 사칠논변의 발단이 된 「천명도」에 대하여

방현주 ( Hyun Joo Bang ) 한국철학사연구회 2014 한국 철학논집 Vol.0 No.40

사단칠정논변四端七情論辨은 이황李滉과 기대승奇大升사이에 벌어진 논쟁으로, 사단四端과 칠정七情 그리고 이기심성론理氣心性論에 대하여 심도 있는 이해를 공유하였던 조선의 대표적인 철학논쟁 중 하나이다. 일반적으로 사칠논변은 정지운鄭之雲이 그린 「천명도天命圖」의 “四端發於理, 七情發於氣”라는 사칠설四七說을 이황이 “四端理之發, 七情氣之發”로 수정하였고, 이 수정된 사칠설이 적힌 「천명신도天命新圖」에 대해 기대승이 의문을 제기한 데서 시작되었다고 알려져 있다. 그러나 정지운과 이황이 「천명도」를 수정한 과정과 사칠논변 제1서~제4서의 내용에 의하면, 기대승이 문제를 제기한 「천명도」는 기존의 이해와는 달리 「천명신도」가 아니라 「천명구도天命舊圖」일 가능성이 높다. 본 논문은 1996년에 이에 대한 문제를 제기한 김용헌의 「고봉 기대승의 사칠논변과 천명도」의 논거를 바탕으로 그의 주장을 검토하고, 마지막으로 「천명도설후서天命圖說後서」와 「천명도설天命圖說」의 내용을 근거로 사칠논변의 발단이 된 천명도가 「천명구도」임을 확인하고자 한다. The Four-Seven Debate(四端七情論辨), this is the debate between Yi Hwang(李滉) and Ki Dae-seung(奇大升), in-depth understanding about the Four Beginnings(四端) and Seven Emotions(七情), theory of Li-Ki and Mind-Nature(理氣心性論), also is one of the Joseon Dynasty period`s major philosophical debate. Typically, the Four-Seven Debate(四端七情論辨) is known to have begun with Jung Ji-woon(鄭之雲)`s Chunmyongdo(天命圖) has been modified by Yi Hwang(李滉), that is from “四端發於理, 七情發於氣” to “四端理之發, 七情氣之發”. However, according to the process of modifying Chunmyongdo(天命圖) and the contents of the Four-Seven Debate(四端七情論辨)`s the first to forth letter, Chunmyongdo(天命圖), Ki Dae-seung(奇大升) raised the issue, is probably not Chunmyongsindo(天命新圖) but Chunmyonggudo(天命舊圖). This paper attempted to analyze this problems through different editions of Chunmyongdo(天命圖), the first to forth letter of the Four-Seven Debate(四端七情論辨), Chunmyongdoseol(天命圖說) and Chunmyongdoseo lhuseo(天命圖說後서), finally try to prove that the Chunmyongdo(天命圖), cause a dispute of the Four-Seven Debate(四端七情論辨), is Chunmyonggudo(天命舊圖) not Chunmyongsindo(天命新圖).