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최원석,Choi, Won-Seok 한국정보통신기술협회 2011 TTA저널 Vol.133 No.-
영화 속에 등장하는 방사선은 평범한 파충류를 거대한 괴물 고질라로 만들거나 사람을 녹색 괴물 헐크로 만들어 버린다. 또한 언론에 비친 방사선은 마치 '살인 광선'처럼 우리 주변에서 가장 멀리해야할 것으로 비춰지고 있다. 최근의 한 드라마에서는 국익을 위해 신형 원자로 전문가를 서로 납치하기 위해 정보기관들 끼리 치열한 첩보전을 벌이는 내용이 나오기는 했지만 여전히 방사선에 대한 이미지는 부정적이다. 하지만 알려진 것과 달리 방사선은 수많은 사람의 목숨을 살리는 '생명의 빛'이기도 하다. 그렇다면 방사선이 어떻게 생명을 살리는데 도움을 줄 수 있는 것일까?
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클러스터 초상자성체 산화철 나노입자를 이용한 색채학적 해석 기반 당 측정
최원석,기재홍 대한의용생체공학회 2020 의공학회지 Vol.41 No.6
Superparamagnetic iron oxide nanoparticles (SPIONs) are approved by the Food and Drug Administration (FDA) in the United States. SPIONs are used in magnetic resonance imaging (MRI) as contrast agents and targeted delivery in nanomedicine using external magnet sources. SPIONs act as an artificial peroxidase (i.e., nanozyme), and these reactions were highly stable in various pH conditions and temperatures. In this study, we report a nanozyme ability of the clustered SPIONs (CSPIONs) synthesized by the oil-in-water (O/W) method and coated with biocompatible poly(lactic-co-glycolic acid) (PLGA). We hypothesize that the CSPIONs can have high sensitivity toward H2O2 derived from the reaction between a fixed amount of glucose and glucose oxidase (GOX). As a result, CSPIONs oxidized a 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS) commonly used as a substrate for hydrogen peroxidase in the presence of H2O2, leading to a change in the color of the substrate. We also utilized a colorimetric assay at 417 nm using various glucose concentrations from 5 mM to 1.25 μM to validate β-D-glucose detection. This study demonstrated that the absorbance value increases along with increasing the glucose level. The results were highly repeated at concentrations below 5 mM (all standard deviations < 0.03). Moreover, the sensitivity and limit of detection were 1.50 and 5.44 μM, respectively, in which CSPIONs are more responsive to glucose than SPIONs. In conclusion, this study suggests that CSPIONs have the potential to be used for glucose detection in diabetic patients using a physiological fluid such as ocular, saliva, and urine.
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최원석,홍석윤,송지훈,권현웅,박일룡,설한신,김민재 대한조선학회 2021 International Journal of Naval Architecture and Oc Vol.13 No.1
The broadband noise can be dominant or important for total characteristics for marine propeller noise representing the minimum base of self-noise. Accurate prediction of such noise is crucial for survivability of underwater military vessels. While the FW-H Formulation 1B can be used to predict broadband trailing edge noise, the method required experiment measurements of surface pressure correlations, showing its limitations in generality. Therefore, in this study, the methods are developed to utilize wall pressure spectrum models to overcome those limitations. Chase model is adopted to represent surface pressure along with the developed formulations to reproduce pressure statistics. Newly developed method is validated with the experiments of airfoils at different velocities. Thereafter, with its feasibility and generality, the procedure incorporating computational fluid dynamics is established and performed for a propeller behind submarine hull. The results are compared with the experiments conducted at Large Cavitation Tunnel, thus showing its usability and robustness.
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최원석,신영주,김하경,이가영,Won Seok Choi,MD,Young Joo Shin,MD,PhD,Ha Kyoung Kim,MD,PhD,Kayoung Yi,MD,PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.12
Purpose: In the present study we compared the intraocular pressure (IOP) after cataract surgery according to incisional techniques. <br /> Methods: Patients who underwent phacoemulsification with intraocular lens implantation were divided into 2 groups: clear corneal incision group (CC group), and scleral tunnel incision group (ST group). All complicated cases were excluded. IOP was measured preoperatively and at 1 week, 1, 3, 6, 12, 18 and 24 months after surgery.<br /> Results: Seventy-seven patients (100 eyes) were enrolled in the present study; CC group (28 patients, 33 eyes), ST group (49 patients 67 eyes). Preoperative IOPs in both groups were not significantly different (p = 0.908, student’s t-test). IOP in the CC group at 1 week after surgery significantly decreased 2.22 ± 2.57 mm Hg compared to preoperative IOP (p < 0.001, repeated-measures ANOVA with post hoc analysis), and the IOP of the ST group decreased 2.11 ± 2.50 mm Hg (p < 0.001, repeated-measures ANOVA with post hoc analysis). The lowered IOP was maintained for 24 months postoperatively. There was no significant difference in IOP change after surgery depending on incisional techniques (p = 0.848, repeated measures ANOVA).<br /> Conclusions: There may be no difference in IOP lowering effect after surgery depending on incisional techniques. <br /> J Korean Ophthalmol Soc 2013;54(12):1856-1861
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조선후기 고지도에 재현된 지역경관 - 남해안 및 진주를 사례로 -
최원석 경상국립대학교 경남문화연구원 2016 남명학연구 Vol.49 No.-
Maps of the Joseon Dynasty period are landscape texts represented the culture, economic condition, regional cognition, geographical information, political administration, national defense and place names. This paper studied on the Southern coastal area and Jinju landscapes of old maps ; landform, Eupchi, transport, education, religion and cultural landscape from the perspective of the historical geography. Maps of the Joseon Dynasty period representing the southern coastal area were differently reflected according to the geopolitical importance and socioeconomic priority at that times. The reason why maps expression being accurate after Japanese Invasion of Korea in 1592 was changed the condition of military strategic location and economy of the southern coastal area in the late Joseon period. Old maps of Jinju were made in 18C and 19C, especially maps of Jinju Castle and county maps reflecting the historical, geographical, cultural information can be used as the historical geographical restoration materials of jinju landscape. Also, they are useful to know the regional circumstances of historical landscape change from the cross section comparison method. 조선시대의 고지도는 당시의 자연인식, 문화와 경제, 정치‧행정과 국방, 지명및 지리정보 등을 총체적으로 재현하고 있는 경관텍스트이다. 이 글은 남해안및 진주를 사례로 조선후기의 지도상에 재현된 지역경관에 관해 역사지리적인관점으로 살펴보았다. 본 연구는 고지도를 지리정보의 사실적 표현 및 시간단면의 누적이라는 차원을 넘어 사회관계의 재현물이자 해석적 텍스트로 까지 포괄적인 스케일로 접근했다는 점에서 의의가 있다. 관이 주도하여 제작한 조선시대의 고지도는 왕조의 권위와 권력을 표현하는 것으로서, 왕조의 정치사회적통치 질서를 구현, 강화하는 목적과 기능을 띠고 있다. 조선시대의 남해안 지도에는 지정학적인 중요성과 사회경제적인 비중이 시대적으로 달리 반영되어 있다. 임진왜란을 겪은 후 남해안이 갖는 군사요충지로서의 중요성과 경제적인 비중의 증대로 지도 표현이 정밀해지는 변화가 일어난 것은 국토공간적 중요성에 대한 조선왕조의 정치사회적인 인식이 달라진데 연유한 것이다. 조선후기의 진주 지도에는 위계적 산수체계의 인식, 중앙집권적 통치체계의 구현, 행정중심지적 도로체계의 형태, 이데올로기적 교육종교경관이 재현되어 있다. 현존하는 진주의 고지도는 대체로 18세기와 19세기에 제작되었는데, 특히 진주성도및 군현지도첩의 지도는 지역경관의 복원 자료로 충분히 활용할 수 있다.
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