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      • KCI등재

        Isolation and characterization of antimicrobial-resistant Escherichia coli from national horse racetracks and private horse-riding courses in Korea

        정연수,Jae Won Song,Dae Ho Kim,Sook Shin,박영경,Soo Jin Yang,임숙경,Kun Taek Park,Yong Ho Park 대한수의학회 2016 Journal of Veterinary Science Vol.17 No.2

        Limited information is available regarding horse-associated antimicrobial resistant (AR) Escherichia (E.) coli. This study was designed to evaluate the frequency and characterize the pattern of AR E. coli from healthy horse-associated samples. A total of 143 E. coli (4.6%) were isolated from 3,078 samples collected from three national racetracks and 14 private horse-riding courses in Korea. Thirty of the E. coli isolates (21%) showed antimicrobial resistance to at least one antimicrobial agent, and four of the AR E. coli (13.3%) were defined as multi-drug resistance. Most of the AR E. coli harbored AR genes corresponding to their antimicrobial resistance phenotypes. Four of the AR E. coli carried class 1 integrase gene (intI1), a gene associated with multi-drug resistance. Pulsed-field gel electrophoretic analysis showed no genetic relatedness among AR E. coli isolated from different facilities; however, cross-transmissions between horses or horses and environments were detected in two facilities. Although cross-transmission of AR E. coli in horses and their environments was generally low, our study suggests a risk of transmission of AR bacteria between horses and humans. Further studies are needed to evaluate the risk of possible transmission of horse-associated AR bacteria to human communities through horse riders and horse-care workers.

      • KCI등재

        Mechanisms of quinolone resistance in Escherichia coli isolated from companion animals, pet-owners, and non-pet-owners

        정연수,허윤성,신숙,임숙경,양수진,박용호,박건택 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.4

        The present study investigated the prevalence and mechanisms of fluoroquinolone (FQ)/quinolone (Q) resistance in Escherichia (E.) coli isolates from companion animals, pet-owners, and non-pet-owners. A total of 63 E. coli isolates were collected from 104 anal swab samples, and 27 nalidixic acid (NA)-resistant isolates were identified. Of those, 10 showed ciprofloxacin (CIP) resistance. A plasmid-mediated Q resistance gene was detected in one isolate. Increased efflux pump activity, as measured by organic solvent tolerance assay, was detected in 18 NA-resistant isolates (66.7%), but was not correlated with an increase in minimum inhibitory concentration (MIC). Target gene mutations in Q resistance-determining regions (QRDRs) were the main cause of (FQ)Q resistance in E. coli. Point mutations in QRDRs were detected in all NA-resistant isolates, and the number of mutations was strongly correlated with increased MIC (R = 0.878 for NA and 0.954 for CIP). All CIP-resistant isolates (n = 10) had double mutations in the gyrA gene, with additional mutations in parC and parE. Interestingly, (FQ)Q resistance mechanisms in isolates from companion animals were the same as those in humans. Therefore, prudent use of (FQ)Q in veterinary medicine is warranted to prevent the dissemination of (FQ)Q-resistant bacteria from animals to humans.

      • KCI등재

        시군구 실업자 총계 추정을 위한 설계기반 간접추정법

        정연수,이계오,이우일 한국통계학회 2003 응용통계연구 Vol.16 No.1

        본 연구에서는 현행 경제활동인구조사 체계에 근거하여 대영역 내의 시군구 단위 행정자치구역들에 대한 실업통계들을 생산할 수 있는 소지역 추정법이 제안된다. 고려된 소지역 추정량들은 합성 추정량, 복합추정량과 같은 설계기반 간접 추정량들이며 이러한 추정량들에 대한 평균제곱오차 추정식이 경제활동인구조사 체계 하에서 산정되어 시군구 단위 소지역 추정값들에 대한 정확도의 측도로써 활용된다. 2000년 12월 충북지역의 경제활동인구조사 자료로부터 이 지역 내의 10개 시군구 단위 행정자치구역들에 대한 실업자 총계 및 잭나이프 평균제곱오차가 본 연구에서 제시된 추정절차에 의해 추정된다. 시군구 단위 실업자 총계 추정값들의 신뢰성은 이들 추정값들의 상대편향(Relative Bias)과 상대오차제곱근(Relative Root Mean Square Error)에 의해 평가된다. 현행 한국 경제활동인구조사체계 하에서 복합추정량이 다른 추정량들에 비해 매우 안정적임을 밝힌다. In this study, we suggest the method of small area estimation based on the Economically Active Population Survey (EAPS) data in producing unemployment statistics for the local self-government areas (LSGAs) within large areas. The small area estimators considered are design-based indirect estimators such as the synthetic and composite estimators. The jackknife mean square error was used as a measure of accuracy of such small area estimators. The total unemployed and jackknife mean square errors of the 10 LSGAs within the large area of ChoongBuk region are derived from the estimation procedure suggested in this study, using EAPS data of December 2000. The reliability of small area estimators was assessed using the relative bias values and relative root mean square errors of these estimators. We find that under the current Korean EAPS system, the composite estimator turns out to be much more stable than other estimators.

      • KCI등재

        지역마케팅 콘텐츠 품질이 방문의도에 미치는 영향: 페이스북을 대상으로

        정연수,정대율 한국인터넷전자상거래학회 2017 인터넷전자상거래연구 Vol.17 No.6

        In recent years, the advancements of social networking services have caused the spread of information and contents. Therefore many local governments are actively using SNS for regional marketing, trying to promote their local brands in order to reinvigorate local economies. This study proposed a structural model in order to verify the relationship between the characteristics of regional marketing contents and it's performance. The analysis was conducted based on the data obtained from the contents analysis of the expert panels in order to verify the effect of regional marketing contents. The results are as follows. All the contents quality factors are influence on visiting intention through the mediating variables such as empathy and communication effectiveness. As a result of the direct and indirect effect analysis, information sufficiency and contents reality were more influential than other variables. The results say that the quality of contents is critical factor to the decision of destination selection and visiting intention.

      • KCI등재

        Validity of the Buttoning Test in Hand Disability Evaluation of Patients With Stroke

        정연수,김애령,박은희,양원종,허재원,오현민,민유선,김철현,정태두,이양수 대한재활의학회 2018 Annals of Rehabilitation Medicine Vol.42 No.1

        Objective To investigate the relationship between the buttoning test and Jebsen-Taylor Hand Function Test (JTHFT), and to determine the validity of using the buttoning test as a tool to evaluate hand disability in patients with stroke. Methods This was a retrospective study of the medical records of 151 ischemic stroke patients affecting the dominant hand. Patients underwent the buttoning test and JTHFT for their affected hand. All patients were divided into three groups depending on how quickly they fastened a button (group A, not completed; group B, slowly completed over 18 seconds; and group C, completed within 18 seconds). Results The button fastening time was negatively correlated with the total score and subtest scores of the JTHFT. Patients who experienced difficulty during the buttoning test had lower mean scores in the JTHFT (group A, 28.0±23.9; group B, 62.9±21.7; group C, 75.4±13.3; p<0.0001, Jonckheere-Terpstra test). We observed significant differences in JTHFT scores among the three groups (p<0.017, Mann-Whitney U-test), although there were considerable overlaps in JTHFT scores between the groups. Significant differences were also found in the subtest scores of the JTHFT, which include fine hand motor function (writing letters, p=0.009; moving small objects, p=0.003; stacking checkers, p=0.001 between groups B and C), among the three groups. Conclusion Considering its relationship with the JTHFT and validity, the buttoning test can be considered appropriate for evaluation of hand disability in patients with stroke.

      • KCI등재

        기술창업기업에서 기업가의 비즈니스모델 인식과 경영성과 간의 관계 연구

        정연수,윤동주,조성의 사단법인 인문사회과학기술융합학회 2019 예술인문사회융합멀티미디어논문지 Vol.9 No.6

        In recent years, “start-ups” have become a key issue for economic revival and sustainable growth around the world. Development of innovative business models and technology-based start-ups are being emphasized in many countries. In this research, the relationship between entrepreneur’s perceived business model characteristics and managerial performance in technology-based start-ups was analyzed based Data was collected from entrepreneurs and managers in start-up companies. As a result of the research, the characteristics associated with customer segments, revenue sources, key activities, and key partnerships among characteristics of business models have a significant effect on the qualitative performance of the technology-based start-up. and customer segment, value proposition, customer relationship, key resource, and cost structure had impact on the quantitative performance. Customer segmentation and value proposition differentiating from other companies affect significantly managerial performance. In addition, key activities and cost structures among business model components need to be focused to improve quantitative performances in technology-based start-ups. 최근 ‘창업’은 세계 여러 국가들에서 경제의 활력 회복과 지속적 성장을 위한 핵심 이슈가 되고 있다. 특히 신산업 창출, 아이디어 및 지식기반 창업과 관련된 기술창업과 혁신적 비즈니스모델의 개발이 강조되고 있으며 이에 대한 각국 정부의 정책적 지원과 관심도 늘어나는 추세다. 본 연구에서는 기술창업기업에서 기업가의 비즈니스모델 특성 인식과 경영성과 간에는 어떤 관계가 있는지 파악해 보았다. 연구결과를 보면 비즈니스 모델 특성 중 고객세그먼트, 수익원, 핵심활동, 핵심파트너쉽과 관련된 특성이 기술창업기업의 질적 성과에 유의한 영향을 주는 것으로 나타났으며 고객세그먼트, 가치제안, 고객관계, 핵심자원, 비용구조의 요소가 재무적 성과를 포함한 양적 성과에 유의한 영향을 주는 것으로 확인되었다. 기술창업기업에서 목표고객 세분화, 그리고 타 기업과 차별화할 수 있는 가치제안에 대한 기업가의 인식이 경영성과 창출에 있어 무엇보다도 중요한 요인이 되고 있다. 또한 재무적 성과의 창출과 관련해서는 비즈니스모델 구성요소 중 핵심활동과 비용구조에 대한 기업가의 인식이 중요한 영향요인이 되고 있음을 본 연구결과가 설명해 준다.

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