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정건식 대한영상의학회 1993 대한영상의학회지 Vol.29 No.1
To evaluate criterial for detecting corpus callosum (CC) abnormality, measurements of GG were done in 100 Korean adults on midline sagittal T1 weighted images using the spin echo technique with a 2.0 Tesla MR unit. The mean($\pm$ SD) anteroposterior diameter of CC, and the mean ($\pm$SD) thicknesses of genu, body, transition, and splenium were 71.1$\pm$5.0, 11.2$\pm$1.6, 5.7$\pm$1.0, 3.6$\pm$1.o, and 11.6$\pm$1.6mm, respectively. The outlines of CC were traced directly from the scans, and the maximal anteroposterior length of the CC was divided into quartiles. Area measurements of the anterior quartile, body, splenium, and whole CC were made with a digitizer pad and computer, and the mean ($\pm$SD) areas of these were 2.11$\pm$36, 194$\pm$36, 205$\pm$34, and 610 $\pm$90mm, repectively. The following ratios were calculated ; Maximum anteroposterior diameter of CC/length of brain, area of anterior quartile/area of whole CC, area of body /area of whole CC, and area of splenium/area of whole CC. There was a statistically significant increase of maximum anteroposterior diameter of CC/ length of braing by age, and a statistically significant decrease of the area of the body by age. However, there were no statistically significant differences of all measurements between males and females.
전신성 홍반성 낭창에서 폐 및 늑막 병변의 고해상 전산화단층촬영 소견
정건식 대한영상의학회 1993 대한영상의학회지 Vol.29 No.5
To evaluate the high-resolution computed tomography (HRCT) findings of pleuropulmonary invement in systemic lupus erythemato년 (SLE), we analyzed HRCT findings of 12 patients of clinically confirmed SLE with respiratory symptoms. In four patients, HRCT findings before and after chemotherapy were compared. The common HRCT findings were ground-glass opactiy (100%), bronchial wall thickening (66%), patchy parenchymal opacity (58%), septal or intralobular line thickening (58%) micronodule (58%), central core prominence (41%), small pleural effusion (91%) and pericardial effusion (33%). Follow-up HRCT obtained after treatment showed significant improvement of pleural effusion (4/4), pericardial effusion (3/3), pericardial thickening (1/1) patchy opacity (2/2), and ground glass opacity (2/4). But bronchial wall thickening (2/2) and micronodule (2/2) were not improved. Although there are no pathognomonic HRCT findings in SLE, bilateral small pleural effusion, ground glass opacity, subpleural patchy opacity, and micronodule are common and suggertive findings in the pleuropulmonary involvement of SLE.
양현경,박미숙,한경화,엄건식,정용은,최진영,방승민,강창무,성진실,김명진 대한암학회 2024 Cancer Research and Treatment Vol.56 No.1
Purpose Clinical prognostic criteria using preoperative factors were not developed for post–neoadjuvant therapy (NAT) surgery of pancreatic ductal adenocarcinoma (PDAC). We aimed to identify preoperative factors associated with overall survival (OS) in PDAC patients who underwent post-NAT curative-intent surgery and develop risk stratification criteria.Materials and Methods Consecutive PDAC patients who underwent post-NAT curative-intent surgeries between 2007 and 2020 were retrospectively analyzed. Demographic, laboratory, surgical, and histopathologic variables were collected. Baseline, preoperative, and interval changes of computed tomography (CT) findings proposed by the Society of Abdominal Radiology and the American Pancreatic Association were analyzed. Cox proportional hazard analysis was used to select preoperative variables associated with OS. We developed risk stratification criteria composed of the significant preoperative variables, i.e., post-NAT response criteria. We compared the discrimination performance of post-NAT response criteria with that of post-NAT pathological (yp) American Joint Cancer Committee TNM staging system.Results One hundred forty-five PDAC patients were included. Stable or increased tumor size on CT (hazard ratio [HR], 2.58; 95% confidence interval [CI], 1.58 to 4.21; p < 0.001) and elevated preoperative carbohydrate antigen 19-9 (CA19-9) level (HR, 1.98; 95% CI, 1.11 to 3.55; p=0.021) were independent factors of OS. The OS of the patient groups stratified by post-NAT response criteria which combined changes in tumor size and CA19-9 showed significant difference (p < 0.001). Such stratification was comparable to ypTNM staging in discrimination performance (difference of C-index, 0.068; 95% CI, –0.012 to 0.142).Conclusion “Any degree of decrease in tumor size on CT” and CA19-9 normalization or staying normal were independent favorable factors of OS. The combination of the two factors discriminated OS comparably to ypTNM staging.