암의 치료 및 전이 억제를 위한 케모카인의 응용

장미라,성인옥,강광일,이혜영,백상기,김영상 충남대학교 생물공학연구소 2003 생물공학연구지 Vol.9 No.1

Chemokines take part in the migration of developmental embryonic cells, lymphocytes, eosinophils and dendritic cells. Chemokines are also related to the angiogenesis and function as a coreceptor during the infection of HIV(human immunodeficiency virus) to T lymphocytes. Recently, tumor metastasis was found to mimic the migration of lymphoid cells into inflammatory sites by chemoattraction. Several chemokines have potential therapeutic applications, mainly in cancer through their ability to attract subpopulations of lymphoid ce1ls and also through their angiostatic effects. The nature of their receptors, which are seven-transmembrane G-protein-coupled receptors, also makes them compelling candidates as therapeutic targets in many areas where chemokines are involved. Metastasis is a nonrandom process, that is, certain types of cancer preferentially metastasize to particular sites. The preferential target organs for metastasis are highly correlated with their chemokine profiles. Chemokines are eagerly waiting for therapeutic applications to selectively induce, modulate, or prevent cellular interactions in the immune response.

미술과 학습지도 내용에 대한 고찰 : 5차 교육과정 교과서를 중심으로

장미라 韓國美術敎科敎育學會 1994 師鄕美術敎育論叢 Vol.2 No.-

한국어 의문․부정 관형사의 사용 양상과 교육 내용 선정에 관한 연구 -‘어느’, ‘어떤’, ‘무슨’을 중심으로-

장미라 한국어문학회 2018 語文學 Vol.0 No.142

This study aims to examine the aspect of use and educational contents selection of Korean interrogative indefinite prenouns such as ‘어느’, ‘어떤’, ‘무슨’. To do this, this paper first examines all the semantic function of question and indefinite, and then it organizes the aspect of use of by Korean speakers. The Korean prenouns, ‘어느’, ‘어떤’, ‘무슨’ have been used as an interrogative sentence for ‘choice, explanation, judgment’, indefinite sentence of ‘vague object, target being unrestricted’, or ironical sentence. In Korean textbooks, the interrogative is especially used, and Korean learners show a lot of errors when using the indefinite. Therefore, it's necessary to gift interrogative, indefinite, and ironical use as academic content and confirmed that it may be controlled in basic and intermediate, advanced levels. 이 연구는 의문·부정 관형사 ‘어느, 어떤, 무슨’의 사용 양상을 바탕으로 한국어 학습자를 위한 교육 내용 선정과 제시 방안을 살펴보는 데 목적을 두었다. 이를 위해 먼저 의문과 부정의 의미기능에 대해 알아보고, 다음으로 한국어 화자의 사용 양상을 정리하였다. ‘어느, 어떤, 무슨’은 선택의문, 설명의문, 판정의문, 막연한 대상을 가리키는 부정, 대상이 제한되지 않음을 가리키는 부정, 반어적 용법으로 사용되었다. 한국어교재에서는 주로 의문의 쓰임을 제시하였고 한국어 학습자에게서는 부정의 쓰임에서 오류가 많이 나타났다. 이에 의문뿐 아니라 부정과 반어적 쓰임이 교육 내용으로 제시될 필요가 있으며 초급과 중고급에서 다루어질 수 있음을 확인하였다.

보조자극분자를 이용한 암치료

장미라,윤희령,성인옥,정상원,김용찬,손정희,이혜영,강광일,백상기,김영상 충남대학교 생물공학연구소 2002 생물공학연구지 Vol.8 No.1

Tumor cells express tumor-associated antigen which can be target to the cytotoxic Tlymphocytes. CTL precursor activation requires antigen recognition and cytokine help from Th cells. In this pathway, the cross-presentation mechanism, professional antigen presenting cells first pick up tumor antigen and present the antigen to Th cells. Another pathway is to activate CTL precursor by the direct priming. The tumor cells, however, lack costimulatory signal, which is required for full activation. The lymphocytes recognized specific antigen without costimulatory signal resulted in anergy. Tumor cells engineered to express the costimulatory molecules are better immunogen and induce antitumor immunity. We will discuss the recent progress in tumor therapy using the costimulatory molecules on the basis of the direct priming mechanism.

서울지역 음식점 메뉴의 나트륨 및 칼륨 함량 비교

장미라,홍미선,최부철,한성희,이경아,김리라,이집호,김정헌,정권 한국식품위생안전성학회 2015 한국식품위생안전성학회지 Vol.30 No.2

To determine the contents of sodium (Na) and potassium (K) for restaurant dishes, 194 cases classified 26 kinds of restaurant dishes were collected from restaurants in Seoul and were analysed using the atomic absorption spectroscopy. Average contents of Na and K in Kimchi among restaurant dishes were highest as 554.9±155.5 mg/100g, 225.1±69.1 mg/100g, while average contents of Na and K were lowest in Seolleongtang as 24.2±5.8 mg/100g, 12.7±3.9 mg/100g respectively. The contents between Na and K in restaurant dishes had a strong correlation of positive linear judging from 0.782 (p-value<0.01) of the correlation coefficient. The Na/K ratio of Bulgogi was appropriate as 1.17±0.44, while those of Udon, banquet noodles, Kalguksu were very high as shown more than 10. The contents of Na and K were examined 5 dish groups as Gook/Tang, Jjigae/Jeongol, stir-fried dish, noodle and Kimchi. Average contents of Na and K classified by dish groups were significantly difference (p-value<0.001). Average content of Na among dish groups was highest in Kimchi as 554.9±155.5 mg/100g followed by Jjigae/Jeongol, Gook/Tang, stir-fried dish and noodle. Similar to Na content, average content of K was highest in Kimchi as 225.1±69.1 mg/100g followed by stir-fried dish, Jjigae/Jeongol, Gook/Tang and noodle. The ratio of Na/K by classified groups of dishes was shown as significantly difference (p-value<0.001). Stir-fried dish was 1.18±0.44 close to 1 followed by Kimchi, Jjigae/Jeongol, Gook/Tang, and noodle.

옥동 3층석탑을 다녀와서

장미라 안동대학 안동사연구회 1989 安東史硏究 Vol.3 No.1

대학에 들어와서 처음으로 가는 답사여서 떨리는 마음을 안고 출발했다. 오늘은 신입생을 위해서 시내답사를 가기로 했다고 한다. 옥동3층석탑, 동부동5층전탑, 신세동7층전탑을 보았다. 그 중 신세동7층전탑은 여러 번 보았지만 나머지 두 가지는 그러한 것이 안동에 있다는 사실조차 몰랐었다. 너무나 부끄러운 일이라 생각된다.

비대면 한국어 교실에서 교사의 역할 수행 경험에 대한 질적 사례 연구

장미라 국제한국언어문화학회 2021 국제한국언어문화학회 학술대회 Vol.2021 No.10

사업체 단체급식소의 유형에 따른 급식운영실태 평가

장미라,곽동경 대한영양사협회 1997 대한영양사협회 학술지 Vol.3 No.1

This study was conducted to evaluate the industry foodservice management practices and to suggest guidelines for the effective foodservice management. The survey for the analysis was conducted through the questionaires to dietitians. They were divided into two groups: the white color worker and the blue color worker. The questionnaires were received for a response rate of 73.2%. Statistical data analysis was completed using the SAS programs for descriptive analysis, X^2 test, T-test, F-test, and Fisher's LSD. The results of the study can be summarized as follows: 1) The level of education of dietitians and food cost in the employee feeding operations for the blue color worker was lower than the employee feeding operations for the white color worker. 2) The labor productivity indices were not significantly different according to types of workers. But in the employee feeding operations for the blue color worker, full-time foodservice employees worked more than 10.7 hour per week than their counterpart. This indicates the full-time foodservice employees in the employee feeding operations for the blue color worker performed more loaded work compared to the employee feeding operations for the white color worker. 3) Equipped rate of facilities in the employee feeding operations for the blue color worker was low especially in the food preparation and cooking processes.

국어 소유 상태 구문의 실현 양상 : 있다, 가지다'구문을 대상으로

장미라 국어국문학회 2002 국어국문학 Vol.- No.130

개화기 국어 인용구문 연구 : 독립신문 전산 자료를 중심으로

장미라 경희대학교 인문학연구소 1999 인문학연구 Vol.3 No.-

This paper investigates Korean citation phraseology during the period of Korea's history commonly known as the Age of Enlightenment. The language of this period exhibits a remarkable variety of unique characteristics and expressions. To this end I conduct a statistical and chronological analysis of the Dongnip-Shinmun newspaper (1896-1897). The Dongnip-Shinmun has been chosen for several reasons: it showcases a diversity of linguistic features and idioms; it was widely diffused and highly regarded in its day; and its language, unlike other period texts, reflects contemporary oral usages. To date, scholars have conducted diachronic research on the citation phraseology of Korea's Middle Age as well as that of modern times. The citation phraseology of Korea's Age of Enlightenment, however, has remain by and large unexplored. Hence the inspiration and imperative of the present study.