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      • KCI등재

        중년후기 성인의 배움 활동에 나타난 의미와 진로적응에 관한 질적 탐구

        임도영,원종숙,김성길 한국성인교육학회 2019 Andragogy Today : International Journal of Adult & Vol.22 No.4

        The purpose of this study was to understand the meaning of erudition activities of late-midlife and to understand their career adaptation. For this purpose, we interviewed 7 male and female in terms of their career stories, applied qualitative research method based on the career construction theory. This paper especially focused on meaning of erudition activities in terms of career adaptation, and therefore we interpreted how erudition activities effected on future career adaptation for adults in late mid-life. First, the main purpose of erudition is to explore their career path and improve work ability. Second, erudition activities is instrumental in developing work ability and exploring career path especially those who are in late-midlife. Third, erudition activities and career adjustment have correlation to each other. Erudition activity helps map out one’s career path like as a ‘compass’. This study imply that erudition activities to adults in late mid-life is not only important to prepare their future career path but also find out values and meaning of life time for adults in late mid-life. This study is expected to be useful as a basic data for self–discovery and career adaptation of late-midlife. 본 연구는 중년후기 성인들이 경험한 배움 활동의 의미를 탐색하고 그 속에서 나타난 진로적응을 이해하는 데 목적이 있다. 이를 위해 구성주의 진로발달이론을 바탕으로 7명 남녀의 배움 경험과 진로 이야기를 인터뷰하였으며, 이들이 인식하는 배움 활동의 의미와 이를 통한 진로적응에 관한 기대를 해석하였다. 연구결과는 다음과 같다. 첫째, 참여자들의 배움 활동은 공통적으로 직무․진로 탐색을 위한 배움이라는 특성이 있었다. 둘째, ‘성공 경험’과 ‘사회적 지지’가 사회 환원의 실천적 쓰임새를 위한 추동 요인이었으며, 중년후기 성인들에게 있어서 학습자의 역할은 소홀히 할 수 없는 진로발달과업임을 확인하였다. 셋째, 배움 활동은 진로를 찾아가게 하는 ‘나침반’으로서 배움 활동과 진로적응이 상호 관련됨을 함축하였다. 종합하면, 중년후기 성인들에게 있어서 배움 활동은 각자 삶의 가치와 의미를 추구할 뿐만 아니라 미래의 진로를 준비할 수 있는 디딤돌임을 알 수 있었다. 향후 본 연구가 중년후기 성인의 자아 탐색과 진로적응을 지원할 수 있는 성인학습 연구의 기초자료로 활용될 수 있기를 기대한다.

      • KCI등재후보

        대장암 동물 모델에 대한 이해

        임도영,Lim, Do Young 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.2

        Colorectal cancer (CRC) is a third leading cause of cancer-related death in cancer patients. Sporadic and inflammation-related colon carcinogenesis are major mechanism of colorectal cancer. In vivo CRC models have been developed and implicated to understand their mechanisms upon a different type of CRC. Moreover, recently animal models have played important roles in chemopreventive and preclinical trials over the years. In this mini-review, the aim is to introduce various animal models of CRC and help the understanding to establish in vivo experimental plans according to the cancer type of CRC.

      • KCI등재

        Luteolin이 인간의 대장암세포인 HT-29 세포의 ErbB3 Signaling Pathway에 미치는 영향

        임도영,조한진,박소영,이기원,윤정한 대한암예방학회 2011 Journal of cancer prevention Vol.16 No.2

        Luteolin is 3’,4’,5,7-tetrahydroxyflavone found in various kind of fruits and vegetables. We have previously shown that luteolin decreased HT-29 cell growth by inducing apoptosis and cell cycle arrest. The present study examined whether luteolin downregulates ErbB3 signaling pathway in HT-29 cells. Cells were cultured with or without 60μmol/L of luteolin and/or heregulin (HRG)-β. HRG-β induced proliferation of HT-29 cells and luteolin abrogated this induction. Luteolin decreased both protein and mRNA levels of EGFR, ErbB3 and ErbB2 in HT-29 cells. Immunoprecipitation/Western blot analyses revealed that luteolin decreased HRG-β-induced tyrosine phosphorylation of ErbB3, recruitment of the p85 subunit of PI3K to ErbB3, and ErbB3-associated PI3K activity. Furthermore luteolin decreased HRG-β-stimulated phosphorylation of Akt. Luteolin also decreased extracellular signal-regulated kinase (ERK)1/2. The present results demonstrate that luteolin down-regulates the ErbB3 signaling pathway,which may one of the mechanisms responsible for the growth inhibitory effect on HT-29 cells. (Cancer Prev Res 16, 134-140, 2011)

      • KCI등재

        인간의 전립선암세포주인 DU145 세포와 단핵구인 THP-1 세포의 상호작용이 종양 증식에 미치는 영향

        임도영,조한진,김종대,윤정한 대한암예방학회 2011 Journal of cancer prevention Vol.16 No.3

        Tumor and tumor-microenvironment are most important aspects in recent years. Tumor associated macrophages (TAM) play key roles in tumor-microenvironment. Macrophages are originated from blood monocytes. In this study, we examined whether DU145 androgen-independent prostate cancer cells and THP-1 human monocytes interact each other in vivo and in vitro. In vivo xenograft model, DU145 cells and/or THP-1 cells were inoculated subcutaneously in Balb/c nude mice. Tumor growth was accelerated in a group of co-inoculation of DU145 cells with THP-1 cells compared to only DU145 or THP-1cell-injected group. Immunohistochemistry assay in tumors revealed that Ki67, CD31, and vascular endothelial growth factor (VEGF) expressions were increased by the co-inoculation group. Secretion of IL-6, IL-8 or VEGF were induced when DU145 cells incubated with THP-1 cells. In the present study,we demonstrated that increase of IL-6, IL-8 and VEGF secretion in co-culture of DU145 and THP-1cells may one of the key inducers of promotion in tumor growth of co-inoculation with DU145 human prostate cancer cells and THP-1 human monocytes. (Cancer Prev Res 16, 194-199, 2011)

      • KCI등재

        국내 가축분뇨 자원화 특성을 고려한 OECD 질소수지 산정법의 지역단위 적용 연구

        임도영,류홍덕,정유진,김용석,이재관,Lim, Do Young,Ryu, Hong-Duck,Chung, Eu Gene,Kim, Yongseok,Lee, Jae Kwan 한국물환경학회 2017 한국물환경학회지 Vol.33 No.5

        The Nutrient budget is one of the agricultural-environment indicators of OECD. A nutrient budget measures the surplus as the differential between the inputs and the outputs of within a certain boundary and within a specified period of time (i.e. one year). According to OECD, the annual nitrogen budget for Korea was $245kg\;N\;ha^{-1}$ in 2014, which corresponds to the first position among OECD countries. In Korea in 2014, about 90 % of livestock excreta was composted as solid and liquid manure, which are usually and customarily spread on agricultural land. The objectives of this study are intended to suggest methodology of the regional nitrogen budget as a nitrogen management tool, which considers conversion from raw excreta to composted manures based on the methodology of OECD/Eurostat, and application of the new method in an agricultural region of Korea. As a result, the calculated excess rate of hydrospheric nitrogen surplus was $251kg\;N\;ha^{-1}$ (in the region in 2014), which indicates the presence of potential risks emanating from excessive nitrogen, with regard to both export water and soil environments. The findings also assert that this was shown to be one of the most important elements in the nitrogen budget, which translates to the actual amounts of nitrogen lost during the solid composting process. To better understand the process and the reliability of the method, it is necessary to analyze the sensitivity of the relevant co-efficients used in the method in the near future.

      • KCI등재

        여성 마을활동가의 진로적응 경험에 나타난 평생학습 실천 탐색

        임도영,김성길 한국성인교육학회 2022 Andragogy Today : International Journal of Adult & Vol.25 No.2

        The aim for the study is to explore the career adaptation experiences of ‘female community activists’ in terms of their life-long education. For the research method, based on Mandelbaum(1973)’s concept of life history analysis, there are three categories for analyzing: ‘life dimensions’, ‘turnings’ and ‘adaptation’. As a result of interview, first, in terms of ‘life-long education', the common factor which is impacted on female community activists’ are ‘family environment ties with career', ‘social environment: communication and a sense of independence', ‘Life of a community of practical learning: Discovery of intersection with career path', ‘Life of community activities: community experiences'. Second, the common factor in ‘turnings’ are ‘Footstep to the community: Experience in the community', ‘Career transition: Recognizing role identity'. Third, the common factor in ‘adaptation' are ‘Human and hardware resource expansion: Various survival strategies', ‘Career vocation: Expanding the role of community activists', ‘Career Vision: Realizing a community of practice'. In the study, It found out that there is high possibility of gathering human sources among female community activists. Furthermore, female community activists became the leading subject that they brought understanding of adult learners as social practitioners who positively drive changes in the community. 이 연구의 목적은 여성 마을활동가의 진로적응 경험에 나타나는 평생학습 실천을 탐색하는 데 있다. 연구방법으로는 Mandelbaum(1973)의 생애사 분석관점에 근거하여 ‘삶의 영역’, ‘전환점’, ‘적응’의 영역으로 분석하였다. 연구결과는 다음과 같다. 첫째, ‘삶의 영역’에서의 공통주제는 ‘가족적 조건의 삶: 진로에 반영’, ‘사회적 조건의 삶: 공동체 감수성과 주체의식 형성’, ‘실천학습 공동체의 삶: 진로와 교집합 발견’, ‘마을 활동 실천의 삶: 마을 경험들’로 도출되었다. 둘째, ‘전환점’에서의 공통주제는 ‘마을로의 발디딤: 마을공동체 경험’, ‘진로전환: 역할 정체성 인식’, ‘진로도약: 경험학습을 통한 역할수용’으로 도출되었다. 셋째, ‘적응’에서 통합된 적응방식에서의 공통주제는 ‘인적․물적 자원확장: 다양한 생존전략’, ‘진로 소명: 마을활동가 역할 확장하기’, ‘진로 비전: 실천공동체 실현하기’로 도출되었다. 본 연구는 여성 마을활동가의 진로적응 경험을 탐색하는 가운데 이들의 진로․직업적 역할확장에 대한 다양성과 여성들이 마을공동체 활동을 통하여 인적자본을 구축하는 가능성으로 해석되었다는 점에서 의의가 있다. 또한, 여성 마을활동가들이 마을 변화를 긍정적으로 추동하는 사회적 실천자로서의 성인 학습자에 대한 이해를 제공하였다.

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