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이주희,김제민,이상규,최수연,이주희,이영인,김지희 연세대학교의과대학 2023 Yonsei medical journal Vol.64 No.12
Purpose: Fractional microneedle radiofrequency (FMR) systems are used to treat inflammatory acne and scarring. Nonetheless, few controlled studies have combined this treatment with the traditional ablative fractional laser (AFL). We aimed to assess the safety and efficacy of the combination of FMR and AFL versus AFL alone in treating acne and acne scars. Materials and Methods: In this 20-week, randomized, split-face study, 23 Korean patients with facial acne and acne scars under went FMR and AFL treatments. One half of each patient’s face was randomly assigned to receive FMR+AFL, whereas the other half received AFL alone. Treatments were administered in three consecutive sessions at 4-week intervals. This study investigated the severity of inflammatory acne, acne scars, individual lesion counts, depressed scar volumes, as well as patient and physician satisfaction. In addition, five patients underwent skin biopsy, and sebum output was measured. Results: The FMR+AFL treatment demonstrated superior efficacy compared to AFL alone in terms of inflammatory acne and acne scar grading, lesion counts, and subjective satisfaction. The side effects were minimal and well-tolerated in both groups. Immuno histochemical findings from skin biopsy samples revealed that the application of FMR+AFL could induce an inhibitory effect on sebum secretion at the molecular level. Conclusion: FMR combined with AFL is a well-tolerated and effective treatment modality for inflammatory acne and acne scarring.
구순열 수술 후 흉터를 가진 영유아 환자에서 흉터 복합 레이저요법의 효과 및 안전성에 대한 단일 기관, 후향적 연구
이주희,최수연,김제민,이영인,이주희 대한피부과학회 2022 대한피부과학회지 Vol.60 No.7
Background: Postoperative scars following cleft lip surgery are frequently accompanied by cosmetic and functional problems; therefore, patients with cleft lip scars usually undergo various long-term scar treatment courses. Currently, only a limited number of fractional laser treatment cases of cleft lip scars have been reported. Objective: This study aimed to evaluate the safety and efficacy of the combination laser treatment for hypertrophic scar management following cleft lip surgery. Methods: This single-center retrospective study included 27 patients who underwent cleft lip surgery before 12 months of age. The control group comprising 13 patients received only a silicone gel or sheet for the scars, while the treatment group comprising 14 patients underwent laser treatment with a 1,550 nm non-ablative fractional erbium-glass laser, followed by a 10,600 nm ablative fractional carbon dioxide laser. Intralesional triamcinolone injection (5∼10 mg/mL) was administered immediately after laser treatment. Scar improvement was assessed at 1, 3, and 6 months after surgery using the Vancouver Scar Scale. Results: The mean total Vancouver scar scale showed a statistically significant improvement in the treatment group compared to that in the control group. In the sub-analysis of pigmentation, the vascularity, pliability, and height significantly improved in the treatment group. No differences in the patients’ baseline characteristics between the two groups were noted. No significant adverse effects were observed during the follow-up. Conclusion: Combination laser therapy using fractional lasers and intralesional triamcinolone injection is safe and effective for managing cleft lip surgery scars in infantile patients.
이주희,김창일,백종후,조정호,전명표,정영훈,이영진,이정배,이승대,Lee, Joo-Hee,Kim, Chang-Il,Paik, Jong-Hoo,Cho, Jeong-Ho,Chun, Myoung-Pyo,Jeong, Young-Hun,Lee, Young-Jin,Lee, Jeong-Bae,Lee, Seung-Dae 한국전기전자재료학회 2011 전기전자재료학회논문지 Vol.24 No.3
The osseointegration of dental implant is influenced by many factors such as surface geometry, loading and the amount of bone. Thus, stability of the dental implant should be checked periodically. In order to test the stability of dental implant by using resonance frequency analysis, we designed a structure of transducers and fabricated a piezoelectric devices. Using finite element analysis, the thickness and length of piezoelectric device and transducers were tailorized and the optimized frequency of 10 kHz was obtained. The resonance frequency from simulation analysis and evaluation was estimated to be similar as 10 kHz. The osseointegration was further enhanced with increasing frequency from the evaluation result of the finite element analysis.
이주희,오정민,홍연우,김세기,백종후,이영진,이정배,이승대,Lee, Joo-Hee,Oh, Jung-Min,Hong, Younwoo,Kim, Seiki,Paik, Jonghoo,Lee, Young-Jin,Lee, Jeong-Bae,Lee, Seung-Dae 한국전기전자재료학회 2012 전기전자재료학회논문지 Vol.25 No.12
A piezoelectric ultrasonic bone surgical instrument, usually used to remove the tartar out of teeth or to cut the dentine of the tooth, is a recently popular instrument for dental treatment due to its several merits such as small size, low-electric power and precision control of surgical operation. It has typically two parts of a tip and vibration system which is also composed of head, piezoelectric elements and tail-mass. In order to improve the performance of the instrument, it is important to standardize the size of the vibration system without tip for high performance. In this study, a Finite Element Analysis (FEA) was utilized to optimize the structure of ultrasonic instrument in vibration system. Consequently, this study revealed that influence of several tips on property were minimized and it showed good property at the frequency range of 22~32 kHz.
이주희,권영진,김동은,Lee, J.H.,Kwon, Y.J.,Kim, D.E. Korean Tunnelling and Underground Space Associatio 2014 한국터널지하공간학회논문집 Vol.16 No.1
터널내의 연기거동 및 대피안전성을 평가하기 위하여 수치해석을 수행하였다. 본 연구의 목적은 최근 더욱 길어지고 있는 장대터널의 화재로 인한 연기 및 온도 분포와 안전성을 평가할 수 있는 수치적 방법을 구현하는데 있다. 계산에 사용되는 컴퓨터자원을 최소화하기 위하여 모델로 선정한 터널의 전체길이인 3 km을 사용하는 대신 여러 개의 대피터널이 포함되는 1.5 km만을 해석영역으로 사용하였다. 터널내의 연기거동에 의한 대피자의 안전성을 평가하기 위하여 연기의 밀도에 의한 기시도와 바닥으로부터의 높이를 고려한 SE (smoke environment)값을 사용하였다. 공기 중에 포함된 연기의 밀도는 3차원 전산유체역학을 통하여 구하였다. 이러한 연기 거동에 영향을 미치는 온도분포를 정확하게 모사하기 위하여 터널 벽면을 단열 혹은 일정한 열유속(heat flux) 가정을 사용하는 대신 1차원 열전도(heat conduction)방정식을 이용하여 터널벽면의 온도를 계산하였다. 대피터널간의 거리가 가까울수록 대피자의 안전성은 높아지겠지만 상대적으로 건설비용이 증가하게 된다. 본 연구에서 대피터널의 길이는 250 m로 하였으며 화재 시 제연팬의 운전 조건을 3가지 (팬이 가동되지 않는 조건, 임계풍속이하조건, 임계풍속이상조건)로 나누어 연기의 거동과 온도분포를 고찰하였다. 그리고 화재가 발생한 시간부터 플래쉬오버가 발생한 시간까지의 연기의 거동과 대피자의 상황을 SE를 이용하여 고찰하였다. A numerical analysis on the smoke behavior and evacuee safety has been performed with computational fluid dynamics. The purpose of this study is to build computational processes for an evacuation and prevention of a fire disaster of a 3 km-length tunnel in Korea. To save computational cost, 1.5 km of the tunnel that can include a few cross-passing tunnels is considered. We are going to assess the fire safety in a road tunnel according to the smoke level, which consists of the smoke density and the height from the floor. The smoke density is obtained in detail from three-dimensional unsteady CFD analysis. To obtain proper temperature distributions on the tunnel wall, one-dimensional conduction equation is considered instead of an adiabatic wall boundary or a constant heat flux. The tunnel considered in this study equips the cross passing tunnels for evacuees every 250 m. The distance is critical in both safety and economy. The more cross passing tunnels, the more safe but the more expensive. Three different jet fan operations can be considered in this study; under- and over-critical velocities for normal traffic condition and 0-velocoty operation for the traffic congestion. The SE (smoke environment) level maps show a smoke environment and an evacuating behavior every moment.