모델축약: 프로그램다이어트

이용제,Lee, Yong-Je 한국전산구조공학회 2016 전산구조공학 Vol.29 No.1

The Grand Prize of The Functionality,The Finalist of The Portal,Community

이용제 (사)한국인터넷전문가협회 2005 Web Korea Annual Vol.2005 No.-

Photobacterium phosphoreum을 고정화하기 위한 Carboxymethylcellulose Sodium Salt [CMC] 담체의 이용성 연구

이용제,정성제,허문석,전억한 한국생물공학회 2000 KSBB Journal Vol.15 No.1

1.0%(w/v)의 CMC 담체는 고정화를 유지할 수 있는 점도를 가지며 0.1 M 이하의 양이온과 이온가교결합을 할 수 있는 농도이다. Luminometer tube내의 시료에 유동을 최소화함으로써 산소의 공급을 일정하게 하여 P. phosphoreum을 고정화 30분 후 bioluminescence intensity가 안정되어 바로 측정할 수 있는 장점을 가지고 있었다. 1.0%(w/v) CMC담체는 pH 6.92로 최적조건인 pH 7.0에 근접했으며, 발광기작에 필요한 산소전달(oxygen transfer)이 1.5%(w/v)~3.0%(w/v) CMC 담체보다 뛰어나 Bioluminescence intensity의 안정성을 부여하였다. Cr-화합물인 $Na_{2}CrO_{4}$, $K_{2}CrO_{4}$, $CrO_{3}$, CrK$(SO_4)_{2}$ 및 $CrCl_{3}$의 CMC담체에 대한 민감도는 $\gamma$값을 이용해서 $EC_{50}$값으로 나타내었을 때 $Na_{2}CrO_{4}$, $K_{2}CrO_{4}$, CrK$(SO_4)_{2}$ 및 $CrCl_{3}$ 의 $EC_{50}$값이 1.0%(w/v)CMC에서는 5.4~16.3 g/L으로 1.5%(w/v)~3.0%(w/v) CMC에서는 6.2~555.9 g/L의 범위로 나타났다. 이것은 1.0%(w/v) CMC가 낮은 독성 농도에서 bioluminescence intensity가 50% 감소함을 알 수 있고, 상관계수($R^2$)가 0.911~0.990 으로 높게 산출되었다. 따라서 1.0%(w/v) CMC 담체가 P. phosphoreum의 biolumincsene에 안정성을 주었으며, 독성물질에 가장 민감하다는 것을 알 수 있었다. Bioluminescence of Photobacterium phosphoreum has been used for the detection of pollutants in the environment. Immobilization method was used to maintain the stability of bioluminescence of P. phosphoreum. The carboxymethylcellulose was investigated to find out whether it was suitable for the immobilization of P. phosphoreum as a matrix without disturbing the bioluminescence emission. A maintenance of bioluminescence was determined from the P. phosphoreum immobilized on the various concentrations of carboxymethylcellulose. A relatively high bioluminescence intensity was shown with immobilized cells on 1%(w/v) carboxymethylcellulose. The effect of carboxymethylcellulose concentrations on the sensitivity of Crcompounds including $Na_{2}CrO_{4}$, $K_{2}CrO_{4}$, $CrO_{3}$, CrK$(SO_4)_{2}$ and $CrCl_{3}$ to the bioluminescence intensity. The calculated $EC_{50}$ showed that the linear relations between such substances and bioluminesence intensity were established.

청원군 일개 면에서 산발적으로 신고한 세균성이질 집단 발병 역학조사

이용제,황의경,김종숙,김준영,이복권,구자설,강종원,Lee, Yong-Jae,Hwang, Ue-Kyoung,Kim, Jong-Suk,Kim, Jun-Young,Lee, Bok-Kwon,Koo, Ja-Seol,Kang, Jong-Won 대한예방의학회 2005 예방의학회지 Vol.38 No.2

Objectives: This study was undertaken to investigate the source of infection and mode of transmission of shigellosis, which occurred sporadically among residents and students in a subcounty of Cheongwon county, Chungbuk province, Korea, from June 4 to July 3 2003. Methods: 692 subjects completed a questionnaire and provided a swab for microbiological examinations,and 7 environmental specimens were examined for bacterial organisms. PFGE (pulsed-field gel electrophoresis) and fingerprinting were performed to find the genetic relationship among the temporally associated sporadic isolates. Results: A total of 29 patients had symptoms consistent with the case definition, with 13 confirmed and 16 suspected cases. The frequency of diarrhea was 6 times or more a day (80.8%), with a duration of 1 to 4 days (88.5%) in most cases. The most common symptoms accompanying the diarrhea were fever (80.9%) followed by abdominal pain (76.9%), headache (65.4%), chill (61.5%), vomiting (46.2%) and tenesmus (15.4%). The epidemic curve was characteristic of a person-to-person transmission. The PFGE and fingerprinting demonstrated identical or similar DNA patterns among the 3 Shigella sonnei isolates (A51, A53 and A61 types) found in this outbreak. Conclusion: A genetically identical strain of S. sonnei was estimated to be the cause of this outbreak, and the mode of transmission was most likely person-to-person.

지반-구조물 상호작용을 고려한 기초모델링

이용제,김태진,마리아 펭 한국지진공학회 2012 한국지진공학회논문집 Vol.16 No.3

지반-구조물의 상호작용은 구조물의 동적 해석 및 기초 설계에 있어 지대한 영향을 미침에도 불구하고 그 중요성이 간과되어 왔다. 이는 모델링 과정의 복잡성으로 인해 실무자를 위한 적절한 절차가 미비 하다는 점에서 상당부분 그 이유를 찾을 수 있을것이다. 본 연구에서는 먼저 구조물의 동적 해석이 필수적으로 요구되는 강진지역인 미국 캘리포니아에 위치한 Cal(IT)2 건물을 대상으로지반 경계조건을 달리했을 시 해석상의 차이가 어느 정도 나는지를 검토해 보았다. 기초 모델링 기법의 하나인 Beam on NonlinearWinkler Foundation Model을 Linear Matrix Inequalities Model Reduction 기법을 활용하여 보다 간략하게 사용할 수 있도록 하였다.이렇게 하여 만들어진 대상 건물의 유한요소 모델과 실재 얻어진 가속도 데이터를 비교하여 제시된 방식을 통해 매우 우수한 해석 결과를얻을 수 있음을 보였다. Even with its significant influence on the dynamic analysis and foundation design of structures, sometimes the soil-structure interaction has been ignored during the design process. One of the reasons is due to the fact that the modeling procedures are too complicated to meet the requirements in practice. In this study, using the Cali(IT)2 building in California with high and frequent seismic activities, the analysis differences for different boundary conditions are reviewed. The Beam on Nonlinear Winkler Foundation Model, one of the foundation modeling methods, is modified for easy use by the Linear Matrix Inequalities Model Reduction Technique. The product of the proposed process is applied to create the Finite Element Model. The results show fairly good agreement with the real data acquired from the Cal(IT)2 building.

외래에서 시행하는 어깨 통증의 평가

이용제 대한가정의학회 2021 Korean Journal of Family Practice Vol.11 No.5

Shoulder pain is a common musculoskeletal complaint in primary care practice. Approximately, 20% of the general adult population experience at leastone episode of shoulder pain in their lifetime. To understand the condition, it is important to understand the shoulder anatomy. The causes ofshoulder pain primarily include, impingement syndrome-rotator cuff disease (impingement syndrome), glenohumeral joint disease (adhesivecapsulitis or frozen shoulder), acromioclavicular joint disease, and referred pain. Shoulder pain can be easily diagnosed through analysis of medicalhistory, physical examination, and radiological findings in clinical settings. 어깨 통증은 일차진료 의사가 접하는 매우 흔한 근골격계 문제로일반 성인 인구의 약 20%가 일생에 적어도 한 번은 어깨 통증을 경험한다고 알려져 있다. 어깨 통증의 원인은 크게 충돌증후군-회전근개 질환(충돌 증후군), 견갑상완 관절 질환(유착 관절낭염 또는오십견), 견봉 쇄골 관절 질환 및 관련 통증으로 구분할 수 있으며,병력, 신체검사, 영상의학적 소견을 통해 임상 현장에서 쉽게 진단할 수 있다

예술의 실천적 지혜로서의 디자인과 디자인의 공공성

이용제 한국동양예술학회 2003 동양예술 Vol.7 No.-

Application of Model Reduction Techniques to Jacket Structures

이용제,서빛나,이은택 한국강구조학회 2015 International Journal of Steel Structures Vol.15 No.1

Offshore structures like jackets are exposed to various kinds of external loading conditions and examination of broader rangeof modes and natural frequencies are required for their dynamic analysis. In this study, four model reduction techniques - twomodal truncation methods and two balanced truncation methods - are introduced and applied to a jacket structure. The reductionresults are compared with those of the conventional Paz condensation methods. Four new methods show better fidelity,especially in high frequency ranges than the conventional methods.

Effects of Coenzyme Q10 on Arterial Stiffness, Metabolic Parameters, and Fatigue in Obese Subjects: A Double-Blind Randomized Controlled Study

이용제,Wan-Je Cho,Jong-Koo Kim,이덕철 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.4

This study investigated the effects of coenzyme Q10 supplementation on metabolic parameters, inflammatory markers, arterial stiffness, and fatigue in obese subjects. We performed a randomized, double-blind, placebo-controlled, single-center study on 51 obese subjects with a body mass index (BMI) of ≥25 kg/m2. Subjects were randomized into either a coenzyme Q10 (200 mg/day) group (n = 26, BMI = 27.9 ± 2.3 kg/m2, age = 42.7 ± 11.3 years) or a placebo group (n = 25, BMI = 26.8 ± 2.8 kg/m2, age = 41.3 ± 11.2 years) for a 12-week study. We collected anthropometric measurements, blood for laboratory testing, brachial–ankle pulse wave velocity (baPWV) as an indicator of arterial stiffness, and responses to a fatigue severity scale (FSS) questionnaire at the initial (0 week) and final (12 weeks) visits. A total of 36 subjects successfully completed the study protocol. Serum coenzyme Q10 levels increased significantly from 0.65 ± 0.27 μg/mL to 1.20 ± 0.38 μg/mL in the coenzyme Q10 group (P < .001). Oral administration of coenzyme Q10 did not significantly affect lipid profiles, oxidative and inflammatory markers [including lipoprotein (a), oxidized low-density lipoprotein level, C-reactive protein, and white blood cell count], or baPWV. The mean FSS score decreased significantly from 40.1 to 33.1 in the coenzyme Q10 group (P = .017), but no significant change was seen in the placebo group (P = .464). However, the extents of the change in mean FSS score between the placebo and coenzyme Q10 groups were not significantly different (P = .287). In conclusion, we found no evidence that coenzyme Q10 affects fatigue index, arterial stiffness, metabolic parameters, or inflammatory markers.

Photobacterium phosphoreum을 고정화하기 위한 최적 Carboxymethylcellulose(CMC) 담체의 농도결정

이용제,전억한 경희대학교 생명자원과학연구원 1999 硏究論文集 Vol.20 No.-

CMC 담체는 점도가 큰 물질로 luminometer tube내의 사료에 유동을 최소화함으로써 산소의 공급을 일정하게 하여 bioluminecsence의 intensity를 일정하게 측정 할 수 있고, P phosphoreum을 고정하여 30분 후에 bioluminescence의 안정성을 가지므로 바로 측정할 수 있는 장점을 가지고 있다 독성에 민감하고 bioluminescence에 영향을 주지 않는 CMC의 농도(w/v)의 결정은 중요하며 1%(w/v) CMC 담체에 고정했을 때 bioluminescence의 유지가 가장 안정했으며, Cr 화합물에 대한 민감하게 반응하는 CMC 담체의 EC_50값ㅇ르 г값을 이용하여 산출했을 때 1% CMC 담체에 고정하였을 때 적은 독성 농도에서 민감한 bioluminescence의 감소를 볼 수 있었다. 그러므로 독성모니터용 P phosphoreun의 고정화 담체로 CMC의 1%(w/v)가 최적 농도이다. Bioluminescence of Photobacterium phosphoreum has been used for the detection of pollutants in the environment. Immobilization method was used to maintain the stability of bioluminescence of P. phosphoreum. Carboxymethylcellulose was investigated for immobilization of P. phosphoreum as a matrix without disturbance in bioluminescence emission. Maintenance of bioluminescence was determined from the P. phosphoreum immobilized on the various concentrations of carboxymethylcellulose. Relatively high bioluminescence intensity was observed with cells immobilized on 1%(w/v) carboxymethylcellulose. The effect of carboxymethylcellulose concentrations on the sensitivity of Cr-compounds including Na_(2)CrO_(4), K_(2)CrO_(4), CrO_(3), CrK(SO_(4))_(2) and CrCl_(3) to the bioluminescence intensity was investigated. The calculated EC_(50) showed that the linear relationship between such substances and bioluminescence.