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Performance of Dual Polarized MIMO System using Six-Port Receiver for Cognitive Radio
이상엽,양완철,이정석,김학선,Lee Sang-Yub,Yang Wan-Cheol,Lee Jeong-Suk,Kim Hak-Sun The Korean Institute of Broadcast and Media Engine 2006 방송과 미디어 Vol.11 No.1
Cognitive radio is a paradigm for wireless communication in which either network of wireless node itself changes particular transmission or reception parameters to execute its tasks efficiently without interfering with the licensed users. This paper represents a performance of the cognitive radio technology on dual polarized MIMO system using six-port receiver. Six-port technology is well known direct conversion receiver. In this paper, a six-port phase discriminator based polarization signal separation is shown. That is, the SER(Symbol Error Rate) performance is improved using polarization separator and simple receiver architecture is proposed applying six-port receiver. The six-port technology has priority to adapt changeable frequency system and variable environments for cognitive radio. In general, dual polarized MIMO system has good capacity and quality using polarization separator [1].
Systems-Level Analysis of Genome-Scale In Silico Metabolic Models Using MetaFluxNet
이상엽,Han Min Woo,Dong-Yup Lee,Hyung Seok Choi,Tae Yong Kim,윤홍석 한국생물공학회 2005 Biotechnology and Bioprocess Engineering Vol.10 No.5
The systems-level analysis of microbes with myriad of heterologous data generated by omics technologies has been applied to improve our understanding of cellular function and physiology and con-sequently to enhance production of various bioproducts. At the heart of this revolution resides in silico genome-scale metabolic model. In order to fully exploit the power of genome-scale model, a systematic approach employing user-friendly software is required. Metabolic flux analysis of genome-scale meta-bolic network is becoming widely employed to quantify the flux distribution and validate model-driven hypotheses. Here we describe the development of an upgraded MetaFluxNet which allows (1) construc-tion of metabolic models connected to metabolic databases, (2) calculation of fluxes by metabolic flux analysis, (3) comparative flux analysis with flux-profile visualization, (4) the use of metabolic flux analy-sis markup language to enable models to be exchanged efficiently, and (5) the exporting of data from con-straints-based flux analysis into various formats. MetaFluxNet also allows cellular physiology to be pre-dicted and strategies for strain improvement to be developed from genome-based information on flux dis-tributions. This integrated software environment promises to enhance our understanding on metabolic network at a whole organism level and to establish novel strategies for improving the properties of organ-isms for various biotechnological applications.
두개골 봉합부의 초기 형태발생과정에서 Msx 유전자들의 발현양상
이상엽,박미현,유현모,남순현,김영진,김현정,Lee, Sang-Youp,Park, Mi-Hyun,Ryoo, Hyun-Mo,Nam, Soon-Hyeun,Kim, Young-Jin,Kim, Hyun-Jung 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.1
두개골의 성장은 뇌의 발달과 밀접하게 연관되어 있으며, 두개봉합부 주위 여러 조직들사이의 조화로운 상호작용을 필요로 한다. 두개골의 조기융합으로 알려진 craniosynostosis는 이러한 상호작용의 불균형으로 인해 야기될 수 있으며, craniosynostosis의 원인 유전자의 하나로 Msx2가 알려져 있다. Msx1, Msx2, Msx3로 구성되어 있는 Msx 유전자는 homeobox를 포함하고 있는 전사조절인자로, 초파리의 muscle segment homeobox 유전자의 homologue이다. Msx1과 Msx2 유전자들은 척추동물의 발생과정에서 조직 상호작용하는 여러 부위에 서로 겹치는 양상으로 발현되며 기관형성동안 상피-간엽조직 상호작용과 연관되어 나타나고, BMP와 FGF signaling의 표적 유전자들이다. Mouse 두개골의 시상봉합부와 관상봉합부의 초기 형태발생과정에서의 Msx 유전자들의 기능을 알아보기위해, 태생 15일에서 태생 18일까지의 mouse의 두개골을 이용하여 in vivo 실험을, 태생 15.5일 mouse 두개골을 이용하여 in vitro 실험을 시행하였다. 시상두개봉합부에서는, Msx1은 봉합부의 간엽조직과 dura mater에 발현하였으며 Msx2는 두개봉합부와 dura mater에 강하게 발현되었다. 관상두개봉합부에서는 Msx1, Msx2 유전자 모두 강하게 발현되었으며, 골막에서도 관찰할 수 있었고, Msx1이 Msx2보다 좀더 광범위하게 발현되었다. In vitro 실험결과, BMP2 bead 주위로 Msx1 mRNA와 Msx2 mRNA 모두 발현되었으나, FGF2 bead 주위로는 Msx1만 발현되고 Msx2는 관찰되지 않았다. 이 결과들을 종합해 볼 때, Msx1, Msx2 유전자들은 태생기 두개봉합부의 형태발생 및 유지를 조절하는데 중요하며, Msx 유전자들은 거의 유사한 발현양상을 나타내고 있으나 이들 유전자들을 조절하는 상위 siganling에 의해 서로 보완적으로 혹은 독립적으로 기능을 나타내고 있음을 시사해 주고 있다. The development of calvarial bones is tighly co-ordinated with the growth of the brain and needs of harmonious interactions between different tissues within the calvarial sutures. Premature fusion of cranial sutures, known as craniosynostosis, presumably involves disturbance of these interactions. Mutations in the homeobox-containg gene Msx2 cause human craniosynostosis syndrome. Msx genes, which are consist of Msx1, Msx2 and Msx3, are homeobox-containg transcripton factors, and were originally identified as homologue of Drosophila msh(muscle segment homeobox) gene. Msx1 and Msx2 genes, expressed mostly in overlapping patterns at multiple site of tissue interactions during vertebrate development, are associated with epithelial-mesenchymal interactions during organogenesis, targets of BMP and FGF signaling. To elucidate the function of Msx genes in the early morphogenesis of mouse cranial suture, we analyzed the expression of them by in situ hybridization during embryonic(E15-E18) stage, and did vivo experiments in E15.5 mouse using rhBMP-2, rhFGF-2 protein soaked bead. In the sagittal suture, Msx1 was expressed in the mesenchyme of suture and the dura mater, Msx2 was intensely expressed in the sutural mesenchyme and the dura mater. In the coronal suture both of Msx genes were expressed intensely in the sutural mesenchyme and expressed in the periosteum also. Msx1 had a broader expression pattern than Msx2. BMP2 beads induced expression of both Msx1 and Msx2, FGF2 beads induced expression of Msx1, but not Msx2. Taken together, these data suggest that Msx1 and Msx2 genes have important role in regulating the morphogenesis and maintenance of embryonic cranial suture. Both of Msx genes are expressed similarly but because of their upstream signaling, they function dependently or cooperatively according to change of signaling molecule.
전문(全文) DB 구축(構築)에 의한 한국통신연구정보관리(韓國通信硏究情報管理) 시스템 개발(開發)
이상엽,안현수,이양옥,Lee, Sang-Yeob,Ahn, Hyun-Soo,Lee, Yang-Ok 한국과학기술정보연구원 과학기술정보센터 1993 Journal of Information Science Theory and Practice Vol.24 No.1
한국통신(韓國通信) 연구개발단(硏究開發團)에서는 사내(社內) 각 연구부서(硏究部署)에서 발생하는 각종 최신 연구정보(硏究情報)의 원문(原文)을 축적(蓄積) 공동활용(共同活用)하기 위하여 한국통신연구정보관리(韓國通信硏究情報管理) 시스템(KTRIMS)을 개발(開發)하였으며, 본(本) 고(稿)에서는 KTRIMS의 구성(構成)과 특징(特徵)을 중심(中心)으로 기술(記述)하였다. KTRC(Korea Telecom Research Center) has developed the KTRIMS(Korea Telecom Research Information Management System) to keep and share the full text of the various up-to-date research information which many research institutes in KT have produced. This paper has presented the structure and the features of the KTRIMS.