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      • KCI등재

        DBS(Deep Brain Stimulation)를 시행한 Essential Tremor 환자의 진전 간정격 치험 1례

        양동호,이경윤,신현승,조송현,임창선,임준혁,윤석훈,이한 대한침구의학회 2010 대한침구의학회지 Vol.27 No.6

        Objectives : The purpose of these case is to observe the effect of prescription of liver supplementation on essential tremor patient who was operated DBS. Methods : The patient was treated by prescription of liver supplementation. The improvement of patient was judged by tremor scale and VAS(visual analog scale). Results : After treatment patient’s tremor scale grade and VAS score were generally decreased. Conclusions : The prescription of liver supplementation might be an effective method to treat the essential tremor patient who was operated DBS.

      • KCI등재후보

        Paraquat 중독환자에서 Free Radical Scavenger 를 이용한 치료경험

        양동호,홍세용,김영통 대한내과학회 1996 대한내과학회지 Vol.51 No.1

        The purpose of this paper is to report three cases of severe paraquat intoxication treated successfully with multiple antioxidants combination therapy of superoxide dismutase inhalation by nebulizer, intravenous administration of aminoacids, vitamin C and E. Three cases of the patients with paraquat intoxication were treated with Superoxide dismutase inhalation by nebulizer, packed RBC transfusion, intravenous injection of aminoacids, Vitamin C and Vitamin E. Case-1 was a 35 year old woman, swallowed 6 mouthfuls of 20% paraquat for the purpose of suicide. The plasma paraquat concentrations were 2133 ng/ml at 2 hours retrospectively. Case-2 was a 50 year old woman, swallowed two mouthful of 20ra paraquat. The plasma paraquat concentrations were 3522 ng/ml at 6 hours, 1358 ng/ml at 12 hours, 85 ng at 18 hours, and 8 ng/ml at 24 hours retrospectively. Case-3 was a 55 year old man who drank 2 mouthfuls of 20% paraquat. The plasma paraquat concentrations were 1172 ng/ml at 10 hours, 189 ng/ml at 16 hours, and 16 ng/ml at 22 hours retrospectively. All of the three cases were treated successfully and discharged without specific complication except exertional dyspnea in case. We found that the mortality of paraquat intoxication could he decreased by various efforts to improve free radical scavenger which are easily available in clinic. Further controlled study is necessary to prove it.

      • KCI등재후보
      • SCOPUSKCI등재

        말기 신부전 환자에서 신 이식후 혈중 Homocysteine 농도의 변동

        양동호,전진호,홍세용 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.3

        A prospective study of vitamin B6, B12, folate, and homocysteine levels was carried out in 7 kidney transplant(KT) recipients. The first sample for the basal level was drawn on the morning of the KT day before the start of cyclosporine injection. Thereafter, serial blood samples were taken every day until the serum creatinine level decreased below 1.5 mg/dl and then every 2 or 3days until discharge. The serum creatinine level decreased to below 1.5 mg/dl within 3days except for cases 4 and 6. The homocysteine levels decreased markedly in synchronisation with serum creatinine levels increased during the first 7days and then declined together with serum creatinine levels but went up again after a few days. The levels of B6, and vitamin B12 do not continue to decrease after the levels of serum creatinine have decreased to 1.5mg/dl, while homocysteine levels go up progressively. In conclusion, contrary to our expectation, the level of homocysteine rebounds a few days after KT following a transient decline. A deficiency of folic acid, vitamin B6 and vitamin B12 does not seem to cause hyperhomocysteinemia in KT recipients. It is necessary to pay attention to hyperhomocysteinemia in KT recipients, especially when the recipients have an atherosclerosis-related complication.

      • KCI등재

        FC200 소재의 평면연삭 가공특성에 관한 연구

        양동호,이상협,차승환,이종찬,Yang, Dong-Ho,Lee, Sang-Hyeop,Cha, Seung-Hwan,Lee, Jong-Chan 한국기계가공학회 2022 한국기계가공학회지 Vol.21 No.6

        Automobile brake discs are a major part of automobiles that are directly related to driver safety, and prevention of judder and squall noise is very important. This phenomenon occurs for complex reasons such as the precision and assembly of the brake module, and the material of the brake disc. The purpose of this study is to analyze the effect of the grinding wheel's grain size on the grinding conditions when machining cast iron, the material of the brake disc, and to derive the optimal grinding conditions through this.

      • KCI등재

        당뇨병성 신증: 일곱 가지 궁금증

        양동호,이소영 대한의사협회 2020 대한의사협회지 Vol.63 No.1

        Diabetic kidney disease is a microvascular complication of diabetes mellitus and the leading cause of end-stage renal disease resulting in renal replacement therapy. Approximately 30% to 40% of diabetic patients have diabetic kidney disease, which contributes to a significant increase in morbidity and mortality. Microalbuminuria is considered the gold standard for diabetic kidney disease diagnosis; however, its predictive value is restricted. Although blood glucose control, blood pressure control, and angiotensin converting enzyme inhibitors have been the primary treatment strategies, there are no definitive treatment modalities capable of inhibiting the progression of kidney dysfunction in these patients. This study was undertaken to answer seven questions regarding the various aspects of diabetic kidney disease. Why does it develop? what kind of factors affect its development? How is it diagnosed? What are its possible biomarkers? When is a kidney biopsy necessary? What are the preventive and therapeutic options? And what are the novel treatments?

      • 인간 대뇌피질에서 고칼륨에 의한 [^3H] Norepinephrine 유리의 특성

        양동호,조규박,김형근 의과학연구소 1998 全北醫大論文集 Vol.22 No.2

        It has been reported that norepinephrine(NE) and Υ-aminobutyric acid(GABA) play important roles in epileptic seizure. IN human central nervous system, however, characteristics of NE release and the influe-nce of GABA have not been elucidated yet. In this study, the mechanism of autoregulation [^3H]NE release evoked by high-potassium and the influence of GABAergic drugs were investigated in epileptic human ce-rebral cortex slices. Potassium stimulated [^3H]NE release in a dose-dependent manner. High potassium(15mM)-evoked release of [^3H]NE was abolished by removal of calcium from incubation media. Tetrodotoxin(TTX), also, profoundly inhibited [^3H]NE release. Clonidine and oxymetazoline, agonists for α_2-adrenocep-tor, inhibited the potassium-evoked release of [^3H]NE in a dose-dependent manner, respectively. Yohim-bine, an antagonist for α_2-adrenoceptor, potentiated [^3H]NE release in a dose-dependent manner. The inhi-bitory effect of clonidine on [^3H]NE release was antagonized by 0.1 μM of yohimibine. however, phenyle-phrine and methoxamine, agonists for α_1-adrenoceptor, did not inhibit the potassium-stmulaed release of [^3H]NE Desipramine, a NE transporter blocker, potentiated [^3H]NE release in a dose-dependent manner. Baclofen, a GABA_B agonist, inhibited the potassium-stimulated [^3H]NE release. The inhibitory effect of bac-lofen was antagonized by 5-aminovaleric acid(5-AV), a GABA_B antagonist. Neither, muscimol, a GABA_A ago-nist, nor bicuculline, a GABA_A antagonist, influenced on the potassium-stimulaed [^3H]NE release. These results suggest that high potassium-stimulated release of NE is autoregulated by α_2-adrenoceptor, and released NE is removed by Ne transporter from synaptic cleft, that the potassium-stimulated release of NE can be regulated by GABA receptors, not GABA_A but GABA_B, in human cerebral cortex. (KEy words : Human Cerebral cortex, norepinephrine release, opioid receptor)

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