우수논문소개 : 뉴런 생존 단백질 B23/nucleophosmin (NPM)의 뉴런사멸 단백질 GAPDH/SIAH complex 억제 기전 연구

안지인,이상배 생화학분자생물학회(구 한국생화학분자생물학회) 2013 생화학분자생물학회 소식 Vol.33 No.1

한국인 영어학습자들의 발음오류 분석

안지인,정현성 대구대학교 사범대학 부설 교육연구소 2005 敎育硏究 Vol.1 No.1

This paper examines the patterns of Korean EFL learners' English pronunciation difficulties in terms of segmental and suprasegmental features. It also aims to present effective English pronunciation teaching techniques to improve communicative competence of Korean EFL learners. The paper presents the importance and theoretical justification for English pronunciation teaching. General properties and theoretical backgrounds of English pronunciation teaching are presented. It overviews the history of English pronunciation teaching from the audio-lingual method to community language learning. The paper examines how these methods were applied to Korean English education curriculum, specifically to English pronunciation teaching. This paper concludes that it is necessary to provide teachers with English pronunciation teaching training program to improve their teaching skills in Communicative Language Learning. A wide variety of teaching materials also need to be developed for more effective pronunciation teaching. 본 논문에서는 발음교육의 측면에서 한국인 영어학습자들이 가지는 영어발음의 문제점들을 고찰하고, 의사소통기능을 원활하게 하기 위하여 한국인 영어학습자들이 학습해야 할 언어자질들에 대하여 제시하였다. 언어자질의 내용적 측면을 제시하기 위해, 영어의 분절자질과 초분절자질에 대해 분석하고, 이러한 자질들이 의사소통중심 영어발음교육에 어떻게 적용될 수 있을지 모색해 보았다. 또한 청화식 교수법에서 의사소통중심 영어발음교육에 이르기까지의 영어발음교육의 이론을 고찰하여, 이러한 영어발음교육의 이론들이 한국의 영어교육 과정에는 어떻게 적용되어 왔는지 분석하고, 이러한 분석을 바탕으로 효과적인 영어발음 지도방안을 모색하고, 영어발음교육이 지향해야 할 방향을 제시하였다.

코로나 시대의 헤어미용 소비가치와 서비스 품질이 점포 선택 특성에 미치는 영향

안지인,진용미 한국미용학회 2022 한국미용학회지 Vol.28 No.6

The purpose is to provide basic data necessary for marketing strategies for the beauty industry, which has rapidly shrunk since COVID19, by investigating the impact of beauty consumption value and service quality on store selection characteristics that have changed in the COVID-19 era. As for the effect of consumption value on store selection characteristics, the visible value of receiving discriminatory services or feeling special was the highest, and the response and empathy were the highest in the effect of service quality on store selection characteristics. In order to improve service quality in beauty services through contact with customers, it is considered most important to increase expertise through employee education, and if a service experience is provided beyond recognition and expectation through personalized services or products, it can provide services suitable for changed consumption value. In future follow-up studies, it is expected that in-depth research will be continuously conducted by expanding the size of the sample and further subdividing it.

성인의 원하지 않는 성행동 응낙과 애착이 이성관계만족에 미치는 영향

안지인,고영건 한국여성심리학회 2014 한국심리학회지 여성 Vol.19 No.3

This study is to explore the effects of consensual unwanted sex and attachment on satisfaction with romantic relationship. A survey was conducted on 69 adult couples (138 persons) who are aged 20 and over and currently in a relationship, and the data from 62 couples (62 men, 62 women) who completed the self-report scales was utilized. The subjects were asked to answer questionnaires including the Experience of Close Relationship Scales (ECRS), the Scale of Satisfaction with Romantic Relationship, and the Consensual Unwanted Sex Scale. The result are as follows; First, women's consensual unwanted sex is negatively correlated with their relationship satisfaction. Second, women are more likely to consent to unwanted sex as their attachment anxiety increases. Third, women's consensual unwanted sex has a direct effect on satisfaction with relationship and their attachment anxiety has an indirect influence on satisfaction through the consent of unwanted sex. Fourth, women's consensual unwanted sex shows a significant effect on women's relationship satisfaction whereas it does not exhibit a significant effect on the relationship satisfaction of their partners. The implications and the limitations of this study and the future research directions are discussed.

Neuroprotection Signaling of Nuclear Akt in Neuronal Cells

안지인 한국뇌신경과학회 2014 Experimental Neurobiology Vol.23 No.3

Akt is one of the central kinases that perform a pivotal function in mediating survival signaling in a wide range of neuronal cell typesin response to growth factor stimulation. The recent findings of a number of targets for Akt suggest that it prohibits neuronal deathby both impinging on the cytoplasmic cell death machinery and by regulating nuclear proteins. The presence of active Akt in thenuclei of mammalian cells is no longer debatable, and this has been corroborated by the finding of multiple targets in the nucleus ofPC12 cells. However, it is also clear that the nuclear Akt signaling exists independent of the cytosolic Akt signaling, thereby showinga distinctive feature of nuclear Akt signaling as opposed to its cytosolic counterpart. The principal objective of this review is tosummarize our current state of knowledge regarding nuclear Akt signaling in neuronal survival, and to introduce current theoriesregarding the roles of nuclear Akt in neuron.

내재된 편향성과 차별을 완화한 한국어 인공지능 동화 생성 모델 〈프랭클린〉

안지인(Jiin An),이육샛별(Saetbyeol Leeyouk),장예원(Yewon Jang),정다샘(Dasaem Jeong) 한국HCI학회 2023 한국HCI학회 학술대회 Vol.2023 No.2

〈프랭클린〉은 언어 생성 인공지능 모델을 통해 아이들이 동화 속 주인공이자 작가가 되어 AI 모델과 동화를 공동 창작하는 인터렉티브 웹서비스이다. 기존 한국어 언어 모델이 사회의 차별과 혐오를 그대로 반영한 데이터셋으로 학습한 것과 달리 비윤리적이고 편향적인 표현을 생성하지 않도록 방지하는 개발 과정을 거쳤다. 평등한 동화를 생성하는 인공지능 모델〈프랭클린〉은 아이들에게 보다 다양한 사회상을 반영한 동화를 제공하는 플랫폼으로서 활용된다.

내재된 편향성과 차별을 완화한 한국어 인공지능 동화 생성기 구축

안지인(Jiin An),이육샛별(Saetbyeol Leeyouk),장예원(Yewon Jang),정다샘(Dasaem Jeong) 한국디지털콘텐츠학회 2023 한국디지털콘텐츠학회논문지 Vol.24 No.7

〈Franklin〉is an interactive service that enables children to become the protagonists and authors of fairy tales in collaboration with an AI language generation model. Considering the inclusion of social prejudices and outdated social norms in existing fairy tales and the fact that Korean language models are trained on datasets that reflect discrimination and hatred in society, 〈Franklin〉 was designed to prevent the generation of unethical and biased expressions. During the process of building a Korean fairy tale dataset, explicit expressions of hatred and profanity were deleted, unnecessary data were removed by detecting cruel or unethical parts included in some classic fairy tales, and grammatical errors were minimized to increase the effectiveness of the small training dataset. Based on the constructed dataset, the model was fine-tuned to implement the tone of the fairy tales, and the word embedding values of the model were adjusted to mitigate the inherent gender bias. Experiments were conducted to complement contextuality and generate coherent stories, and the model was fine-tuned based on the results. A web service was designed to enable children to create fairy tales using the trained model, which serves as a platform for providing fairy tales that reflect more diverse social norms to children.

NCS 기반 교육과정의 효율적 운영을 위한 교수・학습 및 평가 방법 요구 분석

이민욱,김대영,안지인 한국직업교육학회 2017 職業 敎育 硏究 Vol.36 No.3

The purpose of this study was to analyze the need for teaching-learning and assessment methods suitable for the National Competency Standards (NCS) based curriculum at the high school level, and to draw policy support measures. In order to do so, the teaching-learning and assessment methods of the NCS-based curriculum — which is to be applied to all specialized high schools from 2018 — were analyzed, and the requirements and priority for each teaching-learning and assessment method suitable for the NCS-based curriculum were drawn from questionnaire results. Results demonstrated that for the NCS-based curriculum, simulation, project method, and modular instruction were found to be the most suitable teaching-learning methods, and observation, self-evaluation and peer evaluation were considered the most appropriate evaluation methods. Based upon these findings, policy suggestions were made regarding these issues: 1) To operate a training program for NCS teaching-learning and assessment capacity building, 2) to disseminate the NCS teaching-learning and assessment methods management manual and well-practiced exemplary cases, 3) to reinforce on-job NCS teaching-learning and assessment methods consulting, 4) to vitalize studies on NCS-based teaching-learning and assessment methods, 5) to develop and distribute online education contents, and 6) to set up an online community for NCS education officials. 이 연구에서는 고교 단계의 NCS 기반 교육과정에 적합한 교수・학습 및 평가 방법에 대한 요구도를 분석하고 정책적 지원 방안을 도출하고자 하였다. 이를 위해 2018년부터 모든 특성화고에 적용되는 NCS 기반 교육과정의 교수・학습 및 평가 방법 분석, 설문조사를 통한 NCS 기반 교육과정에 적합한 교수・학습 및 평가 방법별 요구도, 우선순위등을 도출하였는데, 교수·학습 방법은 시뮬레이션, 프로젝트법, 모듈식 수업이, 평가 방법으로는 관찰과 자기 평가 및동료 평가가 최우선 순위로 나타났다. 이를 토대로 1) NCS 교수・학습 및 평가 역량 강화 연수 운영, 2) NCS 교수・학습 및 평가 방법 운영 매뉴얼 및 우수사례 보급, 3) NCS 교수・학습 및 평가 방법 현장 컨설팅 기능 강화, 4) NCS 기반 교수・학습 및 평가 방법 연구 활성화, 5) 온라인 교육 콘텐츠 개발 및 보급, 6) NCS 교육 관계자 온라인 커뮤니티 구축 등을 정책 제언으로 제시하였다.

Identification of a Peptide of the Guanosine Triphosphate Binding Site within Brain Glutamate Dehydrogenase Isoproteins Using 8 - Azidoguanosine Triphosphate

조성우,이종원,안지인,최수영 한국생화학분자생물학회 (구 한국생화학회) 1996 생화학분자생물학회 소식 Vol.16 No.4

The roles of multifunctional protein ErbB3 binding protein 1 (EBP1) isoforms from development to disease

황인우,고효림,안지인 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

The roles of the two isoforms of ErbB3-binding protein 1 (Ebp1) in cellular function and its regulation in disease and development is a stimulating area in current fields of biology, such as neuroscience, cancer biology, and structural biology. Over the last two decades, a growing body of studies suggests have suggested different functions for the EBP1 isoforms in various cancers, along with their specific binding partners in the ubiquitin-proteasome system. Owing to the specific cellular context or spatial/temporal expression of the EBP1 isoforms, either transcriptional repression or the activation function of EBP1 has been proposed, and epigenetic regulation by p48 EBP1 has also been observed during in the embryo development, including in brain development and neurologic disorders, such as schizophrenia, in using an Ebp1 knockout mouse model. Here, we review recent findings that have shaped our current understanding of the emerging function of EBP1 isoforms in cellular events and gene expression, from development to disease.