상위음운 중재가 취학 전 조음음운장애 아동의 음운 능력에 미치는 효과

신주영,석동일,박희정,Shin, Ju-Young,Seok, Dong-Il,Park, Hee-Jung 한국음성학회 2006 음성과학 Vol.13 No.3

The purpose of this study was to find an effect of Metaphon Intervention on the improvement of speech intelligibility of preschool children with articulation-phonological disorders. Subjects were 4 preschool children with articulation-phonological disorders. A multiple baseline design across subjects was used to examine the effect of the program. The program consisted of 2 steps. The first step was composed of concept level, sound level, phoneme level, and word level. The second step was on sentence level. Results were as follows: First, metaphon ability of all subjects was improved after the Metaphon Intervention. Second, speech intelligibility of all subjects was improved after Metaphon Intervention. From the results above, Metaphon Intervention can be effective to improve not only phonological awareness and metaphon but also overall speech intelligibility of preschool children with articulation-phonological disorders.

이온성 액체를 이용한 메탄 하이드레이트 생성 촉진효과 연구

신주영 ( Ju Young Shin ),김기섭 ( Ki Sub Kim ),강성필 ( Seong Pil Kang ),문성용 ( Sung Yong Mun ) 한국화학공학회 2013 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.51 No.4

본 연구에서는 가스 하이드레이트 생성 시 첨가된 이온성 액체가 미치는 생성속도의 향상효과를 조사하였다. 이온성 액체로는 Hydroxyethyl-methyl-morpholinium chloride (HEMM-Cl)을 사용하였다. 메탄 하이드레이트의 상평형 곡선을 구하고 생성유도시간과 메탄가스의 소모량을 측정하였다. 20∼20,000 ppm의 HEMM-Cl을 준비하여 하이드레이트가 생성될 수 있는 70 bar, 274.15 K 조건에서 실험을 수행하였다. 하이드레이트 생성 속도에 대한 비교를 위해 순수한 물과 대표적인 촉진제인 sodium dodecyl sulfate를 같은 조건에서 실험하였다. 실험 결과, 이온성 액체인 HEMMCl은 상평형 곡선을 더 높은 압력과 낮은 온도 쪽으로 이동시켰다. 이온성 액체의 첨가 시에는 메탄 하이드레이트의 생성유도시간이 거의 나타나지 않는 것을 알 수 있었다. 메탄가스의 소모량은 모든 농도에서 향상되었고 1,000 ppm에서 가장 많은 양의 가스를 흡수하는 것으로 나타났다. 이온성 액체는 가스 하이드레이트 생성 촉진을 유도하는 것으로 나타났으며 가스저장, 수송 등의 응용기술 개발에 적용이 기대된다. In this study, we investigated the kinetics of gas hydrate formation in the presence of ionic liquid (IL). Hydroxyethyl-methyl-morpholinium chloride (HEMM-Cl) was chosen as a material for the promotion effect test. Phase equilibrium curve for CH4 hydrate with aqueous IL solution was obtained and its induction time and consumed amount of CH4 gas were also measured. Aqueous solutions containing 20∼20,000 ppm of HEMM-Cl was prepared and studied at 70 bar and 274.15 K. To compare the measured results to those of the conventional promoter, sodium dodecyl sulfate was also tested at the same condition. Result showed that the hydrate equilibrium curve was shifted toward higher pressure and lower temperature region. In addition, the induction time on CH4 hydrate formation in the presence of IL was not shown. The amount of consumed CH4 was increased with the whole range of tested concentration of IL and the highest consumption of CH4 happened at 1,000 ppm of HEMM-Cl. HEMM-Cl induced and enhanced the CH4 hydrate formation with a small amount of addition. Obtained result is expected to be applied for the development of technologies such as gas storage and transport using gas hydrates.

여성들의 비만관리 실태 및 만족도에 관한 연구

신주영(Ju-Young Shin),윤미숙(Mi-Sook Yoon) 한국화장품미용학회 2014 한국화장품미용학회지 Vol.4 No.1

As there are growing needs for health and beauty, a slim body shape is viewed as an ideal somatotype. The purpose of this study was to examine the state of obesity management and satisfaction level among women in their 20s to 50s and up and residing in Seoul and Gyeonggi Province by conducting a survey in an attempt to provide accurate information on obesity management and obesity management methods. Concerning the womens awareness of their own obesity, many considered themselves neither obese nor slim. As to the self- perceived obese part of the body, the biggest group found themselves to be obese in every part of the body. 60.5 percent had experience of obesity management, and the biggest change brought by obesity management was having more confidence about appearance. When the state of obesity management was analyzed, exercise therapy was most utilized(33.7%), followed by diet therapy(31.6%), use of obesity management clinics(23.8%) and self-care(10.7%). They considered it necessary to add exercise therapy to what they currently did for the purpose of obesity management. In regard to satisfaction level with obesity management, many answered they were more satisfied when exercise therapy and another therapy were both utilized. 45.9 percent answered diet therapy was effective. Obesity management clinics were also considered effective, and 47.0 percent wanted to receive massage service in the future. As to the effect of self-care, 15.5 percent answered it was effective. Whether they had an intention to take care of obesity or used any related services was analyzed, and 73.6 percent replied they did. Thus, the women were highly concerned about obesity, but their obesity management was done just on a short-term basis.

식이 Vitamin E가 Streptozotocin 유발 당뇨쥐 신장조직에서의 Microsomal Mixed Function Oxidase System에 미치는 영향

신주영(Shin Ju Young),이순재(Rhee Soon Jae) 韓國營養學會 2000 Journal of Nutrition and Health Vol.33 No.6

PVsyst를 이용한 컬러 BIPV 시스템 발전 성능 분석

신주영(Ju Young Shin),임종록(Jong Rok Lim),신우균(Woo Gyun Shin),고석환(Suk Whan Ko),강기환(Gi Hwan Kang),주영철(Young Chul Ju),장효식(Hyo Sik Chang),황혜미(Hye Mi Hwang) 한국태양에너지학회 2021 한국태양에너지학회 학술대회논문집 Vol.2021 No.5

한국 장노년층 소비자의 여가조절요인 연구

신주영(Ju Young Shin),정연국(Yeon Kook Jeong) 한국호텔외식관광경영학회 2004 호텔경영학연구 Vol.13 No.2

The number of senior consumers who have a good knowledge, health and financial power have increased in our society. They are concern about quality of life, and also the recognition of leisure have been changed greatly, they`d like to use the leisure as a tool which can realize their desire that pursue high quality of life. This study researched and analyzed into the leisure moderate factors and influence on leisure participation on consumers on the basis of consumer behavior theory and provide some suggestions for the marketing strategies that can be utilized effectivity in the senior leisure industry. This study used theoretical and empirical approaches and data collected using selecting 429 valid samples for 50-69 aged consumers in Seoul and Kyoungki-do. The result of this study were as follows 1) The relationship between leisure attitude and participation of leisure activity turned out to be moderated by health factor, time factor, financial factor, leisure facility factor, social relationship factor, leisure experience factor. 2) The most moderate factor was leisure experience. 3) The senior consumers who have more health, more time, more good financial status and more facility for leisure more participated in leisure activities than the senior consumers who have not.

전신홍반루푸스 환자에서 발생한 자발성 두개내 저혈압 증후군

신주영 ( Ju Young Shin ),박윤정 ( Yun Jung Park ),김선영 ( Sun Young Kim ),정의성 ( Eui Sung Chung ),고선희 ( Sun Hee Ko ),박정화 ( Chung Hwa Park ),김찬준 ( Chan Joon Kim ),김정호 ( Jeong Ho Kim ),조철수 ( Chul Soo Cho ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.3

Headaches are not only one of the 19 different neuropsychiatric syndromes in SLE but also the most common chief complaint of patients with neuropsychiatric lupus. Approximately 50% of patients with SLE are presumed to have neuropsychiatric phenomena during their illness. There`re no specific serological, radiological or histological biomarkers to confirm the clinical diagnosis of neuropsychiatric lupus. Therefore, physicians tend to try controlling lupus activity especially when the origins of the headache in patients with lupus are difficult to define. However, neuropsychiatric lupus can only be diagnosed after excluding other causes which is the point. A 47-year-old woman with lupus presented to the emergency department with the sudden onset of postural headache with nausea and vomiting. Through CSF tapping and CT myelography, intracranial hypotension with spontaneous CSF leakage was revealed. Her symptoms promptly improved after therapy using an epidural blood patch. Intracranial hypotension with spontaneous CSF leakage is rare disease, and it has never been reported in patients with SLE before. This case emphasizes the importance of finding out the origin of a headache in patients with lupus.

제네릭 의약품 가격이 점유율에 미치는 효과분석

신주영 ( Ju Young Shin ),최상은 ( Sang Eun Choi ) 한국보건경제정책학회(구 한국보건경제학회) 2008 보건경제와 정책연구 Vol.14 No.1

오리지널 의약품과 같은 효능을 가지면서 값이 싼 제네릭 의약품을 처방, 사용하는 것은 소비자의 약제비 부담을 줄여주고, 국가의 건강보험지출을 합리적으로 하는 수단이 될 수 있다. 제네릭 의약품에 대한 연구가 중요함에도 불구하고, 오리지널과 제네릭을 분류할 수 있는 객관적인 기준과 자료가 없었기 때문에, 우리나라에서는 이에 대한 연구가 활발히 이루어지지 않았다. 본 연구는 청구금액 상위 10대 성분에 한정시켜, 오리지널과 제네릭 의약품의 분류를 위한 객관적 기준을 마련코자 하였으며, 제네릭 의약품의 가격과 사용량 수준을 파악하였다. 연구 결과, 단가가 높은 의약품이 오리지널 의약품이 아닌 경우가 많았으며, 제네릭 의약품의 가격 역전 현상이 빈번하게 발생하는 것을 알 수 있었다. 제네릭 의약품들간의 가격 편차가 크고, 고가 제네릭 의약품의 사용량이 많은 것으로 나타났으며, 제네릭 의약품과 오리지널 의약품간의 가격 차이가 작아질수록 점유율이 커지는 것으로 나타났다. 유럽 11개국에서 제네릭 의약품 대체로 얻을 수 있는 연간 절감금액을 추정한 Simone(2006)의 연구결과와 비교하였을 때, 폴란드를 제외한 10개 국가 모두가 우리나라보다 연간절감비율이 높을 수 있는 것으로 나타났다. 즉 우리나라의 제네릭 사용량은 40%이상으로 성숙시장(Generic Mature Market)으로 분류되지만, 제네릭 의약품 사용으로 인한 이익이 국가의 약제비 절감과 소비자의 본인부담감소로는 연결되고 있지 못하다는 것을 알 수 있었다. 따라서 현재의 제네릭 시장의 크기를 유지 또는 더욱 활성화 시키면서, 제네릭 의약품의 가격인하를 유도할 수 있는 정책의 개발이 필요함을 알 수 있었다. Korea National Health Insurance (KNHI) has spent almost 30% of total expenditure on the prescription drugs since 2000. Encouraging generic drug consumption is known as one way to save the drug cost. This paper aims to explore the volume and price of generic drug consumption in Korea prescription drug market and to investigate the determinants of generic market share. We identified the top 10 high-expenditure chemical entities of the prescription drug market during the period of 2001/01/01~2005/12/31. The rate of generic drug`s expenditure among top 10 sales drugs is consistently 50~60 % from 2001 to 2004, and over 70% on 2005. The volume to value ratio was 0.9~1.1 consistently, that meant the difference of generic price and original drug price was small. To analyze the determinants of generic market share, data on 857 drug products spanning twelve chemical entities were collected for the period of 01/01/2005 to 12/31/2005 from KNHI`s drug benefit database. Generic market share was positively correlated with product price (0.088, p<0.01) and negatively correlated with price difference (-.0.140, p<0.01). On the multivariable regression model, it was found that the product approval year was the most significant factor to affect generic market share: the early-approval product tended to be used more. Price difference was also significant factor to affect the generic market share. In conclusion, we found that Korea had mature generic market that meant the rate of generic usage is very high, comparing those of European countries. Nevertheless the usage of generics was not connected to cost-containment of pharmaceutical expenditure in KNHI due to the high price of generics.

컬러 BIPV 시스템 발전량 추정 방법 제안

신주영(Ju Young Shin),고석환(Suk Whan Ko),신우균(Woo Gyun Shin),황혜미(Hye Mi Hwang),주영철(Young Chul Ju),장효식(Hyo Sik Chang),강기환(Gi Hwan Kang) 한국태양에너지학회 2021 한국태양에너지학회 학술대회논문집 Vol.2021 No.11

의약품사용평가(Drug Utilization Review)에 대한 설문조사: 고양시 의사 및 약사 대상 병용 및 연령금기 약물 처방경험

신주영 ( Ju Young Shin ),이애영 ( Ai Young Lee ),손성욱 ( Seong Wook Shon ),최남경 ( Nam Kyong Choi ),신선미 ( Sun Mi Shin ),박효주 ( Hyo Ju Park ),박병주 ( Byung Joo Park ) 대한보건협회 2014 대한보건연구 Vol.40 No.4

연구목적 : 의약전문가를 대상으로 Drug Utilization Review(DUR) 금기 의약품 사용경험과 DUR정보에 대한 인식도 및 금기 약물 사용 배경을 조사하고자 하였다. 연구방법 : 병용금기 및 연령금기 약물에 대한 의약품사용평가 현황 조사를 위한 설문지를 개발하였으며, 경기도 고양시의 대한의사협회 또는 대한약사회 회원으로 등록되어 있는 의사 612명과 약사 342명를 대상으로 2008년 2월 15일부터 21일까지 방문조사를 실시하였다. 연구결과 : 전체 응답자는 의사 219명, 약사 90명으로 총 309명이 응답하였다. 이중, 병용금기 약물을 한번 이상 처방 또는 조제한 적이 있다고 응답한 사람은 90명(29.1%)이었으며, 병용금기 약물 중 HMG CoA 환원효소 억제제와 triazole계 항진균제 또는 macrolides 계열 약물간의 병용(26.8%)과 ketorolac과 NSAIDs의 병용(26.2%)이 가장 다빈도로 나타났다. 한편, 연령금기 약물을 한번 이상 처방 또는 조제한 적이 있다고 응답한 사람은 82명(26.5%)이었으며, 가장 다빈도 성분은 12세 미만에서 처방 또는 조제한 acetaminophen 서방형 제제(65.0%)인 것으로 나타났다. 금기약물의 처방 또는 조제에 대한 주요 이유로는 과거 처방하였을 때 문제가 없었기 때문인 경우가 34건(25%), 금기약물인줄 몰랐던 경우가 32건(23.5) 으로 꼽혔다. 결론 : DUR 발전을 위해서는 의사, 약사가 처방 또는 조제시 참고할 수 있도록 신뢰도 높은 DUR정보 개발이 필요하며, 더불어 임상 현장에 도움을 줄 수 있는 풍부한 정보 제공과 이와 관련된 교육 및 홍보를 활성화해야 할 것이다. Objective : To evaluate the attitudes and awareness of healthcare professionals (physicians and pharmacists) toward Drug Utilization Review (DUR) and their experiences of prescribing drugs with drug-drug interactions and agecontraindications in Goyangsi, Korea. Methods : Face-to-face interview was conducted using a structured questionnaire for 612 physicians and 342 pharmacists, who were registered with Korean Medical Association or Korean Pharmaceutical Association in Goyangsi between February 15th, 2008 and February 21st, 2008. Results : The total number of respondent was 309, which included 219 physicians and 90 pharmacists. The total number of prescribing or dispensing of drug combinations with drug-drug interactions was 90 (29.1%). The most frequently prescribed drug combination was HMG-CoA reductase inhibitors and triazole antifungals or macrolides (26.8%), which was followed by ketorolac and NSAIDs (26.2%). And the total number of respondents who reported experiences with prescribing or dispensing drugs with age contraindications was 82 (26.5%). The frequency of using extended-release acetaminophen under 12 years of age was the highest. The main reason for prescribing or dispensing contraindicated drugs was that no adverse events were observed with previous use (34 of 118 cases (25.0%)). And 32 cases (23.5%) were due to unawareness of the contraindications by the physicians and pharmacists. Conclusion : A substantial number of physicians and pharmacists had experiences of prescribing or dispensing contraindicated drugs. Continuous education with the development of credible DUR information is necessary for a successful DUR system in Korea.