일반연제 발표 : 부인종양 ; 자궁경부암의 생존분석

서자영,김원규 대한산부인과학회 2001 대한산부인과학회 학술대회 Vol.87 No.-

A Case of Disseminated Penicillium marneffei Infection in a Liver Transplant Recipient

서자영,마영은,이장호,이승태,기창석,이남용 대한진단검사의학회 2010 Annals of Laboratory Medicine Vol.30 No.4

Penicillium marneffei is the only dimorphic fungus among Penicillium spp. that can cause a fatal infection in immunocompromised patients. P. marneffei is endemic in Southeast Asia and eastern China. P. marneffei infection is an AIDS-defining illness and the third most common opportunistic infection in the endemic regions. Here, the authors report a case of disseminated P. marneffei infection in a patient who underwent liver transplantation in China. During the hospital stay, the mold form of the fungus that produced a red wine-colored pigment on the agar plate was isolated from the patient’s urine, transtracheal aspirate, and blood. The fungus was identified as P. marneffei by direct sequencing of the D1-D2 and ITS regions. Thermal dimorphism was also confirmed by subculturing the colony at 37℃. To the best of our knowledge, this is the first Korean case of disseminated P. marneffei infection in a liver transplant recipient. (Korean J Lab Med 2010;30:400-5)

침윤성 자궁경부암에서 편평상피세포암 항원의 유용성

서자영,남영일,이인철,오영림,이태화,박은동,김흥열,윤성도 고신대학교(의대) 고신대학교 의과대학 학술지 2003 고신대학교 의과대학 학술지 Vol.18 No.1

Background : SCC Ag (Squamous cell carcinoma antigen) is a tumor marker for patients with squamous cell carcinoma of uterine cervix and is related with the response of cancer therapy and course of cervical cancer. We investigated the significance of preoperative serum squamous cell carcinoma antigen(SCC Ag) level in invasive cervical carcinoma in relation to stage, cell type, invasion depth, pelvic lymph node metastasis, and parametrium involvement. Materials and Methods : From January 1994 to December 1998, 173 patients were analyzed for the measurement of pretreatment SCC Ag level to clinicopathologic characteristics using chi-square test. Results : Increased pretreatment SCC Ag levels were correlated strongly with unfavorable clinicopathologic characteristics. Chi-square analysis showed that increased stage, deep invasion depth and pelvic lymph node metastasis were associated with significantly higher serum SCC Ag levels. Conclusion : The determination of pretreatment serum SCC Ag level provides a useful prognostic factor in invasive cervical carcinoma.

중앙은행 디지털화폐(CBDC)와 금융거래정보 보호

서자영 한국법학원 2022 저스티스 Vol.- No.189

Central Bank Digital Currency (hereinafter referred to as 'CBDC') is a digital currency issued by the central bank. The issuance and transaction records of CBDC are implemented in CBDC ledgers or electronic devices. It is necessary to protect personal information that can be collected and used in the process of operating the CBDC system. On the other hand, it is necessary to comply with Anti-Money Laundering regulations. In this respect, CBDC cannot be designed to maintain the same level of complete anonymity as cash. Determining the appropriate level of anonymity or personal information protection of the CBDC system is a matter of technology design that sentences various legal principles such as Anti-Money Laundering. Each intermediary institution can acquire personal information when opening a CBDC electronic wallet, and when accessing the electronic wallet after opening. Next, CBDC transaction records such as electronic wallet address, transaction amount, and usage time recorded in the ledger during CBDC transactions can be hash encrypted based on distributed ledger technology and privacy-enhancing technologies. However, in exceptional cases such as financial supervision or law enforcement, it can be designed to identify individuals through decryption procedures. Therefore, CBDC transaction information is not anonymous information under the Personal Information Protection Act, but pseudonym information, in that the possibility of identifying individuals through additional information is open. Information obtained before CBDC issuance and when accessing the CBDC system needs to be stored separately by individual intermediaries on a distinct server from the CBDC transaction ledger. Furthermore, transaction information recorded in the ledger during CBDC transactions should be minimized and pseudonymized as essential information for transactions. This is because it is difficult to change or delete information recorded in the ledger when using distributed ledger technology, and information is continuously accumulated. Transaction transparency should not be guaranteed enough for state agencies to know transaction details without any separate measures. It is necessary to design it to receive transaction information from CBDC ledger nodes for financial supervision or law enforcement. In addition, it is desirable to guarantee the right to choose a payment method by continuing to issue cash and to guarantee the right to use or move CBDC users' transaction records. 중앙은행 디지털화폐(Central Bank Digital Currency, 이하 ‘CBDC’)는 중앙은행이 전자적 형태로 발행하는 화폐이다. 전자적 형태의 속성상 CBDC 원장이나 전자적 기기에 발행 및 거래기록이 담긴다. 설계에 따라서는 전 국민이 사용하는 CBDC 거래이력이 중앙은행 등 특정 기관에 집적될 수 있다. 이에 제도 운영 과정에서 수집·이용 가능한 개인정보에 대한 보호가 필요하다. 한편 CBDC는 금전이고, CBDC 거래는 금전거래로서 자금세탁방지 관련 규정을 준수할 필요가 있다. 이러한 측면에서 CBDC에 대하여 현금과 동등한 수준의 완전한 익명성을 유지하도록 설계할 수는 없다. CBDC 시스템의 개인정보 보호에 대한 적절한 수위를 결정하는 것은 자금세탁방지 등 여러 법익을 형량한 제도 설계의 문제이다. CBDC 발행과 유통 시 중앙은행이나 상업은행 등 중개기관이 취득하는 금융거래정보는 살아 있는 개인에 관한 정보와 그렇지 않은 정보로 나눌 수 있다. CBDC 발행과 유통의 시간적 순서에 따라 취득 가능한 개인정보를 살펴보면, 개별 중개기관은 발행 전 전자지갑 개설 시, 개설 이후 전자지갑 접속 시 본인확인을 위하여 그 자체로 개인을 식별할 수 있는 정보를 취득한다. 다음으로 CBDC 거래 시 원장에 기록되는 전자지갑 주소, 거래금액 및 이용시간 등 거래내역은 분산원장기술과 개인정보 보호 강화 기술을 기반으로 해시화(암호화)하여 개인을 식별할 수 없도록 설계할 수 있다. 그런데 금융감독이나 법 집행과 같은 예외적 경우 암호 해제 절차 등을 통해 다시 개인을 식별할 수 있는 설계가 가능하다. 이처럼 암호화 절차를 거친 거래정보는 원래의 상태로 복원하기 위한 추가 정보의 사용·결합을 통해 개인을 식별할 가능성이 열려 있다는 점에서 개인정보보호법상 익명정보라기 보다는 가명처리를 거친 가명정보에 해당한다. CBDC 발행 전과 시스템 접속 시 취득하는 신원 확인을 위한 정보는 개별 중개기관이 CBDC 거래원장과 분리된 서버에 별도로 저장하여 개인정보 유출 시 파급효과를 최소한도로 할 필요가 있다. 나아가 CBDC 거래 시 원장에 기록되는 거래정보는 거래에 필수적인 정보로 최소화하고 가명처리해야 한다. 분산원장기술을 사용하는 경우 원장에 기록된 정보의 변경이나 삭제가 어렵고 계속하여 정보가 집적된다는 점에서 더욱 그러하다. 한편 중앙은행이 개인의 소액결제기록을 취득하지 아니하고 상업은행 등 중개기관별 거래정보의 총액을 수집하는 방식으로 구현하는 경우, 중앙집중식 정보수집 주체가 등장하는 것을 방지하는 측면에서 유리하다. 나아가 국가기관이 별도의 조치 없이도 거래 내역을 알 수 있을 정도로 거래 투명성을 보장할 수는 없고, 예외적 경우에 금융감독 내지 법 집행을 위하여 분산원장 참여기관으로부터 거래정보를 제공받도록 설계할 필요가 있다. 그리고 현금 발행을 병용하여 지급수단 선택권을 보장하고, CBDC 이용자의 거래기록에 관한 이동권 등을 보장하는 것이 바람직하다.

침윤성 자궁경부암에서 편평상피세포암 항원의 유용성

서자영,남영일,이인철,오영림,이태화,박은동,김흥열,윤성도 고신대학교 의학부 2003 高神大學校 醫學部 論文集 Vol.18 No.1

Background : SCC Ag (Squamous cell carcinoma antigen) is a tumor marker for patients with squamous cell carcinoma of uterine cervix and is related with the response of cancer therapy and course of cervical cancer. We investigated the significance of preoperative serum squamous cell carcinoma antigen(SCC Ag) level in invasive cervical carcinoma in relation to stage, cell type, invasion depth, pelvic lymph node metastasis, and parametrium involvement. Materials and Methods : From January 1994 to December 1998, 173 patients were analyzed for the measurement of pretreatment SCC Ag level to clinicopathologic characteristics using chi-square test. Results : Increased pretreatment SCC Ag levels were correlated strongly with unfavorable clinicopathologic characteristics. Chi-square analysis showed that increased stage, deep invasion depth and pelvic lymph node metastasis were associated with significantly higher serum SCC Ag levels. Conclusion : The determination of pretreatment serum SCC Ag level provides a useful prognostic factor in invasive cervical carcinoma.

근적외투과분석법에 의한 현미의 Acid value 정량분석

서자영,이수정,신명곤 우송대학교 산업연구소 2000 산업연구 Vol.2 No.1

Infratec 1229 analyzer in determining acid value of whole grain brown rice was applied. The standard error of calibration(SEC) and R2 of acid value were 2.571 and 0.649 respectively. The results showed that acid value of brown rice could be partly analyzed by Near-infrared transmittance spectroscopy.

요추의 퇴행성 변화가 이중에너지 방사선 흡수계측기를 이용한 요추의 측면 골밀도 측정에 미치는 영향 : 앙와위 측면 측정의 유용성

서자영 대한영상의학회 1998 대한영상의학회지 Vol.39 No.5

Purpose : To evaluate the usefulness of supine lateral bone mineral density (BMD) measurement using DXA by comparing AP and lateral spine BMD in patients with degenerative change. Materials and Methods : Six hundred and seventy-two women underwent AP and lateral BMD measurement of L-spine, using DXA. Spur changes and end-plate sclerosis were considered as degenerative change, and osteoporosis was defined according to WHO criteria. The ratio of mid-lateral BMD to AP BMD was calculated and the differences in ratio were analyzed in the degenerative group and controls, according to aging and osteoporosis, using the t test and ANOVA. The correlation coefficiency between aging and AP BMD and lateral BMD, respectively, was calculated. Result : The mLat/AP ratio in the control and degenerative group was 0.710(0.005 / 0.622(0.028 (p=0.003) in the 40-49-year-old group, 0.663(0.006 /0.612(0.016 (p=0.002) in the 50-59-year-old group, 0.626(0.015 / 0.552(0.023 (p=0.007) in the 60-69 year-old group, and 0.717(0.028 / 0.600(0.045 (p=0.076) in those aged over 70. The ratio was 0.656(0.015 / 0.598(0.038(p=0.099) in osteoporosis, 0.684(0.008 / 0.596(0.016 (p=0.000) in osteopenia, and 0.688(0.005 / 0.583(0.019(p=0.000) in normal subjects, showing that lateral BMD is more sensitive than AP BMD, especially in the degenerative group. There was negative correlation between aging and AP BMD(r= -0.545), lateral BMD(r= -0.571), and mid-lateral BMD(r=-0.583). Conclusion : In a selective group of patients with degenerative change, supine lateral BMD measurement of L-spine is useful.

한외여과 시스템을 이용한 전통주의 고품질화

서자영,강현아,이종혁,장규섭 한국식품과학회 1999 한국식품과학회 학술대회 Vol.1999 No.1

A Multi-institutional Study of Prevalence and Clinicopathologic Features of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP) in Korea

서자영,박지현,표주연,차윤진,정찬권,송동은,곽정자,박소연,나희영,김장희,석재연,김희성,홍순원 대한병리학회 2019 Journal of Pathology and Translational Medicine Vol.53 No.6

Background: In the present multi-institutional study, the prevalence and clinicopathologic characteristics of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) were evaluated among Korean patients who underwent thyroidectomy for papillary thyroid carcinoma (PTC). Methods: Data from 18,819 patients with PTC from eight university hospitals between January 2012 and February 2018 were retrospectively evaluated. Pathology reports of all PTCs and slides of potential NIFTP cases were reviewed. The strict criterion of no papillae was applied for the diagnosis of NIFTP. Due to assumptions regarding misclassification of NIFTP as non-PTC tumors, the lower boundary of NIFTP prevalence among PTCs was estimated. Mutational analysis for BRAF and three RAS isoforms was performed in 27 randomly selected NIFTP cases. Results: The prevalence of NIFTP was 1.3% (238/18,819) of all PTCs when the same histologic criteria were applied for NIFTP regardless of the tumor size but decreased to 0.8% (152/18,819) when tumors ≥ 1 cm in size were included. The mean follow-up was 37.7 months and no patient with NIFTP had evidence of lymph node metastasis, distant metastasis, or disease recurrence during the follow-up period. A difference in prevalence of NIFTP before and after NIFTP introduction was not observed. BRAFV600E mutation was not found in NIFTP. The mutation rate for the three RAS genes was 55.6% (15/27). Conclusions: The low prevalence and indolent clinical outcome of NIFTP in Korea was confirmed using the largest number of cases to date. The introduction of NIFTP may have a small overall impact in Korean practice.

디지털자산과 화폐법 - CBDC 동향과 과제 -

서자영 서울대학교 금융법센터 2022 BFL Vol.115 No.-