세퍼드에서 ethylene glycol 독성에 관한 연구

박현종,이오형,임채웅,Park Hyun-Jong,Lee Oh-Hyung,Lim Chae Woong 한국동물위생학회 2005 韓國家畜衛生學會誌 Vol.28 No.1

Ethylene glycol (EG) intoxication in dogs can pose a diagnostic challenge. We investigated the effect of a lethal dose of EG to the Shepherd on blood, urine test, and histopathologic observation. Shepherds were treated orally with EG at $10\;m{\ell}/kg$ body weight. Clinically, EG caused the vomition, depression of central brain. Anion gap was increased, which was decreased pH of blood, The blood osmorality was increased at 3 hours, and BUN and creatinine was increased at 24 hour significantly. The pH of urine decreased. The crystal of calcium oxalate appeared at 6 hours. The amount of crystals increased at 12 and 24 hours. Microscopically, the degeneration of proximal tubules were shown at 1 hour and finally progressed as acute tubular nephrosis at 24 hours. These results suggest that the blood and urine test accompanied with histopathological examination be helpful to investigate the EG intoxication.

K-ε 난류 모델을 적용한 다차원적 수치해석에 의한 실린더 내의 유동에 관한 연구

박현종,김양술,김종억 대한기계학회 1989 대한기계학회 춘추학술대회 Vol.- No.-

무기체계 구성품 신뢰도 검증 시험 설계를 위한 가속수명모델 데이터 베이스 구축 및 의사결정 방법론 연구

박현종,성시일 한국신뢰성학회 2023 한국신뢰성학회 학술대회논문집 Vol.2023 No.6

Pap smear screening for small cell carcinoma of the uterine cervix: a case series and review of the literature

박현종,최영미,정찬경,이산희,임가원,김상운,남은지,김영태 대한부인종양학회 2011 Journal of Gynecologic Oncology Vol.22 No.1

Objective: Small cell carcinoma of the uterine cervix (SMCC) is extremely rare, and an aggressive disease that proliferates rapidly. It was often reported that the diagnostic accuracy of cytologic smears in diagnosing SMCC was low. This is a report of the Severance Hospital experience with the patients suffering from SMCC. Methods: Twenty-seven patients with small cell carcinoma of the uterine cervix were diagnosed and treated at the Severance Hospital from November 1991 to January 2010. The data were analyzed retrospectively, based on the available charts and pathology reports. Various fields, such as chief complaints and symptoms present at first clinic visit, age, International Federation of Obstetrics and Gynecology (FIGO) clinical stage, treatment modality, the 5-year overall survival rate, and recurrence rate were investigated. Results: Among the 27 patients diagnosed with small cell carcinoma of the uterine cervix, 18 of them (66.7%) presented with symptoms, including vaginal bleeding, at the first clinic visit, and the remaining 9 patients (33.3%) showed abnormal Pap smear screening in the process of their routine health check-up. The median age of the patients was 54 years (range, 24 to 77 years). FIGO stage IIB was the most common stage (11 of 27 patients). The 5-year overall survival rate of 21 patients, who could be followed up, was 57.2%. Six patients showed recurrence after remission, and the mean disease free interval of them was 9.2 months (range, 6 to 11 months). Abnormal Pap smear screening results of 9 patients was investigated, and the diagnostic accuracy of the cytologic findings was 22.2%. Conclusion: Our study was consistent with the concept that Pap smear screening might not be helpful in early diagnosis of SMCC considering its low diagnostic accuracy. Further large-scale multicenter prospective studies are definitely needed in order to produce abundant information about optimal therapy and diagnosis.

올바른 애견문화

박현종 로얄에이알씨 주식회사 2003 로얄동물임상의학 Vol.- No.-

Could surgical management improve the IVF outcomes in infertile women with endometrioma?: a review

박현종,김한나,이근호,윤태기,이우식 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.1

Endometriosis is a chronic inflammatory condition that affects fertility and could be toxic to the ovary. Endometriomaper se and surgical interventions for endometrioma significantly reduce the ovarian reserve. Therefore, to preparefor surgical intervention for endometrioma, the high-risk group with decreased ovarian reserve must be considered. There is no evidence to support the use of surgical intervention before in vitro fertilization (IVF) to improve thereproductive outcomes of subsequent IVF in infertile women with advanced-stage endometriosis or endometrioma. As surgical treatment has few benefits, IVF could be recommended immediately for aiding conception in thesewomen. However, the reproductive prognosis of IVF may be worse in the more advanced stages of endometriosis. When dysmenorrhea is severe or when cancer is suspected, surgery prior to IVF may be necessary and justified. Whenthe size of the endometrioma is very large, surgery could be required prior to IVF to facilitate access to folliclesduring oocyte retrieval or to improve the ovarian response to controlled ovarian stimulation. Prolonged pituitarydownregulation in women with surgically diagnosed endometriosis may be helpful to increase the clinical pregnancyrate in subsequent IVF cycles. The purpose of this paper was to review the efficiency and clinical application of thesurgical intervention and IVF for infertile women with advanced-stage endometriosis or endometrioma.

한국의 반격!

박현종 로얄에이알씨 주식회사 2003 로얄동물임상의학 Vol.- No.-

스월 유동이 직분식 디젤 엔진내의 Soot 분포에 미치는 영향에 과한 연구

박현종,정재우,이기형,이창식 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.3

Earth-Rockfill Dam사면파괴에 대한 신뢰도 연구(I)

박현종,이인모 한국지반공학회 1991 지반 : 한국지반공학회지 Vol.7 No.3

본 연구에서는 복합 zone을 가진 rockfill dam성토 재료의 강도정수들과 core zone에서의 간극 수압의 불확정성을 고려할 수 있도록, 성토 재료의 공간적인 변화의 불확실성, 시료수의 제한에 의 한 불확정성에 실험실 결과와 현장 결과와의 차이에 따른 model 오차의 영향을 고려한 종합적인 설계변수들의 불확정성을 규명하였으며 core zone의 간극수압과 rockfill zone의 내부 마찰각을 bayeg 이론을 이용하여 불확정성을 Updating할 수 있는 방법을 제시하였다. 사면 안정 해석에서 시공직후 상, 하류, 만수위 상, 하류 수위, 급강하 시의 2차원 사면안정해석 과 end effect 영향을 고려한 3차원사면 안정해석을 하였다. 본 목적을 위하여 복합 zone을 가진 rockfill dam의 사면 안정해석에서 end effect의 영향을 고려한 3차원 사면안정해석 Program인 "ESTABL"을 개발하였으며, 파괴 사면의 강도정수와 간극수압의 변동계수를 구하는 프로그램 "COV", 복합 zone사면 안전율의 변동계수를 구하는 프로그램 "PCOV"을 개발하였다. 사면안정해석 결과 3차원안전율이 2차원안전율보다 약 200A정도 크게 나타나므로 end restraint 효과가 상당히 큼을 알 수 있다. 3차원사면안정은 근본적으로 system reliability 문제이 므로 안전율의 평균간보다 그 불확정성이 더 큰 영향을 미침을 보여준다. 또한 기초설계 치로 설계 를 마친후 시공중 혹은 추가로 각종 계측치가 있을 때 updating 이론을 이용하여 신뢰도를 증가시 킬 수 있음을 보여주며 강도계수의 변화에 의한 파괴확률의 변화는 점착력의 불확정성이 내부마찰 각의 불확정성보다 민감하게 영향을 미침을 보여준다.찰 각의 불확정성보다 민감하게 영향을 미침을 보여준다. The purpose of this paper is to develop a reliability model for slope stability of Earth-rockfill dams which accounts for all uncertainties encountered. The uncertain factors of the design variables include the cohesion, the angle of internal friction, and the porewater Pressure in each zone. More specifically, the model errors in estimating those variables are studied in depth. To reduce the uncertainties due to model errors, updated design variables are obtained using Bayesian Theory. For stability analysis, both the two-dimesional stability analysis and the three-dimensional stability analysis where the end effects and the system reliability concept are considered are used for the reliability calculations. The deterministic safety factor by the three-dimensional analysis is lager than that by the two-dimensional anlysis. However, the probability of failure by the three-dimensional analysis is about 3.5 times larger that by the two-dimensional analysis. It is because the system reliability concept is used in the three-dimensional analysis. The sensitivity analysis shows that the probability of failure is more sensitive to the uncertainty of the cohesion than that of the angle of internal friction.

가속모델의 가속계수 조사

박현종,김성준,박범식,박소미,성시일 한국품질경영학회 2024 품질경영학회지 Vol.52 No.1

Purpose: This study is to investigate the literature on accelerated tests based on the acceleration model and to provide a compilation of results on the parameters applied in the acceleration model and the test conditions. Methods: This research is conducts a literature review on accelerated tests using the acceleration model, with a focus on test targets, test conditions, and parameter values. The study is organizing the results of this literature review to facilitate their application in the design of reliability tests. Results: A literature review investigated a variety of test targets, test conditions, and parameter values. Conclusion: The results of the literature research conducted revealed various acceleration model parameter. Such literature research on accelerated tests can establish the foundation for reliability test design and contribute to future product development and quality improvement