http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박서용,김정준,김태헌,임수현,한덕현,박병관,김찬교,권기영,최한용,이현무 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.5
Purpose: We aimed to assess the clinical value of endorectal magnetic resonance imaging (MRI) in predicting extraprostatic extension and seminal vesicle invasion in patients with clinically localized prostate cancer. Materials and Methods: A total of 54 patients who underwent radical prostatectomy for clinically localized prostate cancer were retrospectively analyzed. The findings of endorectal MRI, performed at least 3 weeks after biopsy, were compared with the pathological results of radical prostatectomy specimens. The sensitivity, specificity, and accuracy of the detection of extraprostatic extension and seminal vesicle invasion were calculated. Results: The sensitivity, specificity, and accuracy of the endorectal MRI findings were 50.0%, 82.6%, and 77.8% for the detection of extraprostatic extension, respectively, and 75.0%, 92.0%, and 90.7% for the detection of seminal vesicle invasion, respectively. The sensitivity of endorectal MRI in the detection of extraprostatic extension improved as the Gleason score increased. Conclusions: Endorectal MRI findings demonstrated modest sensitivity for predicting extraprostatic extension, whereas specificity was relatively high. In addition, endorectal MRI showed better sensitivity for detecting high-grade tumors.
박서용,전성수,이서연,정병창,서성일,이현무,최한용 대한의학회 2011 Journal of Korean medical science Vol.26 No.3
The present study was performed to determine the incidence and predictive factors of benign renal lesions in Korean patients undergoing nephrectomy for presumed renal cell carcinoma on preoperative imaging. We analyzed the pathologic reports and medical records of 1,598 eligible patients with unilateral, nonmetastatic, and nonfamilial renal masses. Of the 1,598 renal masses, 114 (7.1%) were benign lesions, including angiomyolipoma in 47 (2.9%), oncocytoma in 23 (1.4%), and complicated cysts in 18(1.1%) patients. On univariate analysis, the proportion of benign lesions was significantly higher in female patients, and in patients with smaller tumors, cystic renal masses, and without gross hematuria as a presenting symptom. When renal lesions were stratified by tumor size, the proportion of benign as opposed to malignant lesions decreased significantly as tumor size increased. On multivariate analysis, female gender, smaller tumor size, and cystic lesions were significantly associated with benign histological features. The findings in this large cohort of Korean patients show a lower incidence (7.1%) of benign renal lesions than those of previous Western reports. Female gender, cystic renal lesions, and smaller tumor size are independent predictors of benign histological features.
박서용,이현무 대한의사협회 2010 대한의사협회지 Vol.53 No.2
The purpose of this article is to summarize up-to-date changes and policies in the diagnosis of prostate cancer. The triads of DRE (digital rectal examination), serum PSA (prostate specific antigen), and TRUS (transrectal ultrasound) that directed prostatic biopsy have been considered a gold standard in the early detection of prostate cancer. Even though PSA is a very useful test,its low specificity has made some controversy until now. Moreover, it is not verified whether PSA screening would contribute to the decline in prostate cancer mortality. TRUS directed prostate biopsy also has some criticisms. For example, appropriate number of biopsy core, determination of whether a patient should undergo a repeat biopsy and its timing remain controversial. This article presents guidelines on prostate cancer diagnosis with partial results of randomized controlled trials to verify aforementioned criticisms Since recently published trials show different results regarding the impact of prostate cancer screening on mortality, further analyses are needed to determine the specific parameters for optimal screening (i.e. the age at which screening should begin, re-screening intervals, the age at which screening should be discontinued, and novel screening biomarkers). Unless a new and effective screening biomarker is discovered, PSA will maintain a superlative position for screening of prostate cancer. Hence,we have to find an optimal cut-off value of PSA derivatives for Korean people. With respect to prostate biopsy, current literatures support the use of more extensive biopsy techniques to increase the likelihood of prostate cancer detection.
웨이브렛 패킷 변환을 이용한 적응알고리듬의 수렴속도 향상
박서용,김대성 한국정보기술전략혁신학회 1999 情報學硏究 Vol.2 No.2
최근 들어 신호처리 분야에서 웨이브렛 변환을 이용한 연구가 활발히 진행되고 있다. 본 논문에서는 웨이브렛 변환 영역에서의 적응 알고리듬을 구현하고 비 정제적 신호에 대한 성능을 평가하였다. 입력 신호를 웨이브렛 패킷 변환하여 다해상도 분해하고 NLMS알고리듬을 이용하여 부 밴드에서의 적응 알고리듬을 구현하였다. 제안한 방법을 화이트 가우시안 잡음이 섞인 도플러 신호의 잡음 제거에 적용하여 그 성능을 평가하였다. The wavelet transform is widely used in signal processing application. In this paper, a wavelet domain adaptive algorithm(WPTNLMS) is derived and its performances are evaluated in non-stationary environment. Where the input signals are decomposed by the wavelet packet transform for the multi-resolution adaptive processing. And the NLMS is used as an adaptive algorithm in wavelet domain. The proposed technique is applied to noise cancellation of the Doppler signal which is added with white Gaussian noise.
박서용(Seo Young Park),임수현(Soo Hyun Lim),이건석(Geonseok Lee),서성일(Seongil Seo),전성수(Seongsoo Jeon),이현무(Hyun Moo Lee),최한용(Han Yong Choi),정병창(Byong Chang Jeong) 대한비뇨기종양학회 2011 대한비뇨기종양학회지 Vol.9 No.2
Purpose: To present the therapeutic strategies and long-term follow-up results of testicular germ cell tumors (GCT) based on an 11-year single center experience. Materials and Methods: The medical records of testis cancer cases diagnosed between January 1996 and November 2006 were reviewed. Patient demographics, cancer histopathology and stage, adjuvant therapy, survival data are reviewed and analyzed. Results: A total of 51 testicular GCT, including seminoma in 31, and non-seminomatous GCT (NSGCT) in 20 were enrolled in the present study. Mean patient age at diagnosis was 35.6 years (range 18-69), with a median follow-up of 53 months (range 5-163). There were no cases with bilateral testicular GCT in this study cohort. Among 51patients, 30 (58.8%) were stage I, 10 (19.6%) were stage IIA/IIB, and 11 (21.6%) were IIC/III. Of the 30 patients with stage I testicular GCT, two patients who had been under surveillance showed relapse at retroperitoneal lymph nodes, and both patients cured with salvage chemotherapy. Meanwhile, there was no recurrence in 14 patients who received adjuvant chemo or radiotherapy after radical orchiectomy. The overall 5-year cancer specific survival was 95.9%. Conclusions: Our long-term follow-up results confirm the excellent prognosis for patients with testicular GCT, and indicate that surveillance does not compromise survival. In stage I testicular germ cell tumor, active surveillance could minimize treatment-related morbidity. Before deciding surveillance, however, psychological impacts on patients, economic and social costs in addition to patients’ compliance should also be considered.